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油气藏评价与开发 1994年第1期 89-90页

作者： derek j.Woodward

尽管距地面一定距离飞行的航磁勘探所含的地表附近岩石磁化方面的信息比等高程飞行的航磁勘探的信息要多,但地面效应的修改仍是正确解释的关

关键词：反演航磁数据数学航磁勘探数字模型

Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

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World journal of Gastroenterology 2012年第17期18卷 2061-2066页

作者： Ingmar Knigsrainer derek Zieker jrg Glatzle Olivia Lauk julia Klimek stephan symons Bjrn Brücher stefan Beckert Alfred Knigsrainer Department of surgery University of TübingenHoppeSeyler-Strasse 3D-72076 TübingenGermany Center for Bioinformatics Tübingen Sand 14D-72076 TübingenGermany

AIM:To investigate perioperative patient morbidity/mortality and outcome after cytoreductive surgery(CRs) and hyperthermic intraperitoneal chemotherapy(HIPEC).METHODs:Of 150 patients 100 were treated with cytoreductive surgery and HIPEC and retrospectively *** and postoperative follow-up data were *** mass index(BMI),age and peritoneal carcinomatosis index(PCI) were chosen as selection criteria with regard to tumor-free survival and perioperative morbidity for this multimodal ***:CRs with HIPEC was successfully performed in 100 out of 150 *** patients were excluded because of intraoperative *** PCI was 17(1-39).In 89% a radical resection(CC0/CC1) was *** patient died postoperatively due to multiorgan *** PCI,age nor BMI was a risk factor for postoperative complications/outcome according to the DINDO *** 9% Re-CRs with HIPEC was performed during the follow-up ***:Patient selection remains the most important *** PCI,age nor BMI alone should be an exclusion criterion for this multimodal therapy.

关键词： Peritoneal carcinomatosis single-center experience Hyperthermic intraoperative chemotherapy Complications Risk assessment selection criteria

Waste Management Practices and Profile of selected Key Green House Gases at selected Livestock Farms in Ibadan, Nigeria

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journal of Environmental science and Engineering(B) 2016年第12期5卷 581-592页

作者： Ese Freeman Oghaghare Godson Ana derek Garth shendell Department of Environmental Health sciences Faculty of Public Health University of lbadan Nigeria Center for school and Community-Based Research and Education Rutgers School of Public Health (SPH) Piscataway NewJersey (NJ) 08854 USA Department of Environmental and Occupational Health Rutgers SPH Piscataway NJ 08854 USA Exposure Measurement and Assessment Division Environmental and Occupational Health Sciences Institute Rutgers The StateUniversity of N J Piscataway NJ 08854 USA Center for Global Public Health Rutgers SPH Piscataway NJ 08854 USA

Livestock farm waste contributes substantially to annual worldwide emissions of GHG （Greenhouse Gases）, including CH4 （Methane） and CO2 （Carbon Dioxide）. However, despite evidence of global climate change and its adverse health effects, studies on anthropogenic contributions to the increasing levels of GHG, particularly from livestock waste management practices, have not been adequately explored, especially in less developed countries. This study determined waste management practices and outdoor levels of CH4 and CO2 at three selected livestock farms （A-C） in Ibadan, Oyo state, Nigeria. Each study farm consisted of poultry, cattle and pig units. A 30-point observational checklist documented adequacy of solid waste management practices. Ambient concentrations of CH4 and CO2 at farm buildings and at waste disposal sites were monitored every other day, twice each day of monitoring （morning and evening hours）, for eight weeks during months of september-November in 2013. Average scores for the waste management practices for Farms A-C were 29.6%, 33.3% and 18.5%, respectively. Morning and evening CH4 concentrations in parts per million （ppm） at main buildings of Farms A-C were 2,538 ± 773 and 1,916 ± 662, 2,325 ± 773 and 1,180 ± 483, and 2,389 ± 687 and 1,854 ± 571, respectively. Morning and evening CO2 concentrations （ppm） at Farms A-C main buildings were 350 ± 130 and 330 ± 110, 470 ± 100 and 440 ± 100, and 430 ± 80 and 400 ± 70, respectively. Morning and evening CH4 concentrations （ppm） at Farms A-C waste disposal sites were 2,452 ± 495 and 1,614 ± 372, 1,527 ± 390 and 1,736 ± 269, and 2,345 ± 615 and 1,690 ± 387, respectively. Morning and evening CO2 concentrations （ppm） at Farms A-C waste disposal sites were 330 ± 90, 370 ± 60 and 350 ± 30, respectively. Waste management practices were inadequate; solid waste management practices like infrequent evacuation of slurry waste and open burning of waste may have contributed to the production of CH4 and CO2. This study sugg

关键词： Livestock farms greenhouse gases waste management.

stem cells, immortality, and the evolution of metastatic properties in breast cancer: telomere maintenance mechanisms and metastatic evolution

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journal of Cancer Metastasis and Treatment 2019年第5期4卷 32-40页

作者： Nathaniel j.Robinson derek j.Taylor William P.schiemann Department of Pathology Case Western Reserve University School of MedicineClevelandOH 44106USA Department of Pharmacology Case Western Reserve University School of MedicineClevelandOH 44106USA Case Comprehensive Cancer Center Case Western Reserve UniversityClevelandOH 44106USA

Breast cancer is the most significant cause of cancer-related death in women around the *** vast majority of breast cancer-associated mortality stems from metastasis,which remains an incurable disease *** results from evolution of clones that possess the insidious properties required for dissemination and colonization of distant *** clonal populations are descended from breast cancer stem cells(CsCs),which are also responsible for their prolonged maintenance and continued *** impose a lifespan on cells that can be extended when they are actively elongated,as occurs in ***,changes in telomere structure serve to promote the survival of CsCs and subsequent metastatic *** selection of telomere maintenance mechanism(TMM)has important consequences not only for CsC survival and evolution,but also for their coordination of various signaling pathways that choreograph the metastatic *** the telomere maintenance machinery may therefore provide a boon to the treatment of metastatic breast *** we review the two major TMMs and the roles they play in the development of stem and metastatic breast cancer *** also highlight current and future approaches to targeting these mechanisms in clinical settings to alleviate metastatic breast cancers.

关键词： Breast cancer cancer evolution cancer stem cells metastasis telomerase

锡、钨、铌和钽矿石重选中技术的、经济的和其它的因素

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国外金属矿选矿 1983年第8期 16-32页

作者： derek j.Ottley 李成村

中国和苏联是主要产锡国,马来西亚的锡产量虽有些下降,但仍是世界最大产锡国。主要的锡消耗国为工业化的国家,消耗较多的是美国、西欧和日本。锡的主要用途为镀锡和贱金属合金。过去几年,钽的需要量急剧增长,主要消耗于固态电容器、电... 详细信息

中国和苏联是主要产锡国,马来西亚的锡产量虽有些下降,但仍是世界最大产锡国。主要的锡消耗国为工业化的国家,消耗较多的是美国、西欧和日本。锡的主要用途为镀锡和贱金属合金。过去几年,钽的需要量急剧增长,主要消耗于固态电容器、电子设备和微型计算机及碳化钽。世界钽的生产来源大约一半来自冶炼厂熔渣,主要在泰国和马来西亚,另一半来自矿石的处理。加拿大是最大的矿石产国,来自钽矿公司的 Ber-nic Lake 矿山。含低达3.5%Ta2O6的熔渣现

关键词：混合精矿混合矿细粒锡石硫化矿物硫化物矿物矿物分析螺旋选矿机选矿机械矿石品位尾矿重选厂磨矿回路砷黄铁矿毒砂矿泥中矿再磨跳汰机重选机磨矿机磨机选矿厂加工厂经济

Transient Expression of Virally Delivered Meganuclease In Planta Generates Inherited Genomic Deletions

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Molecular Plant 2015年第8期8卷 1292-1294页

作者： Honig, Arik arikh@*** Marton, Ira Rosenthal, Michal smith, j. jeff Nicholson, Michael G. jantz, derek Zuker, Amir Vainstein, Alexander Danziger Innovations Ltd. Mishmar Hashiva Village Beit Dagan 50297 Israel Precision Biosciences 302 East Pettigrew Street Dibrell Building Suite A-100 Durham NC 27701 USA Institute of Plant sciences and Genetics in Agriculture Robert H. Smith Faculty of Agriculture Food and Environment Hebrew University of Jerusalem Rehovot 76100 Israel

Dear Editor The use of sequence-specific nucleases for plant genomic DNA mutagenesis is an exciting and rapidly developing tech- nology （Voytas and Merchant, 2013; Baltes and Voytas, 2014）. To date, most mutated plants have been recovered from transgenic plants stably expressing nucleases. However, transient nuclease delivery by plant DNA- and RNA-based viral vectors followed by regeneration of plantlets from modi- fied tissues has emerged as an alternative, efficient strategy in some plant species （Marton et al., 2010; Baltes et al., 2014）. Delivery of nucleases by plant RNA viruses is particularly attractive because they typically do not integrate into the plant genome, and therefore the mutated plants are not classified as transgenic （Marton et al., 2013; Voytas and Gao, 2014）.

关键词： DNA 植物 RNA RNA 植物基因组植物接生产科内皮缩血管肽类胰岛素植物

A robust new metric of phenotypic distance to estimate and compare multiple trait differences among populations

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Current Zoology 2012年第3期58卷 426-439页

作者： Rebecca sAFRAN samuel FLAXMAN Michael KOPP Darren E. IRWIN derek BRIGGs Matthew R. EVANs W. Chris FUNK David A. GRAY Eileen A. HEBETs Nathalie sEDDON Elizabeth sCORDATO Laurel B. sYMEs joseph A. TOBIAs David P. L. TOEWs j. Albert C. UY Department of Ecology and Evolutionary Biology University of Colorado Boulder CO 80309 U.S.A. Mathematics and B iosciences Group Faculty of Mathematics University of Vienna A-1090 Vienna Austria Current address Evolutionary Biology and Modeling Group Faculty of Sciences Aix-Marseille University 13331 Marseille France. Department of Zoology University of British Columbia 6270 University Boulevard Vancouver BC Canada V6T 1Z4. Research ＆ Evaluation Methodology School of Education University of Colorado Boulder CO 80309 U.S.A. school of Biological and Chemical sciences Queen Mary University of London London E1 4NS Department of Biology Colorado State University Fort Collins CO 80523 U.S.A. Department of Biology California State University Northridge CA 91330 U.S.A. school of Biological sciences University of Nebraska Lincoln NE 68588 U.S.A. Edward Grey Institute Department of Zoology University of Oxford Oxford OX1 3PS UK Committee on Evolutionary Biology The University of Chicago Chicago IL 60637U.S.A. Department of Biology Dartmouth College Hanover NH 03755 U.S.A. Department of Biology University of Miami Coral Gables FL 33146 U.S.A.

Whereas a rich literature exists for estimating population genetic divergence, metrics of phenotypic trait divergence are lacking, particularly for comparing multiple traits among three or more populations. Here, we review and analyze via simula- tion Hedges＇ g, a widely used parametric estimate of effect size. Our analyses indicate that g is sensitive to a combination of unequal trait variances and unequal sample sizes among populations and to changes in the scale of measurement. We then go on to derive and explain a new, non-parametric distance measure, ＇Aft＇, which is caiculated based upon a joint cumulative distribution function （CDF） from all populations under study. More precisely, distances are measured in terms of the percentiles in this CDF at which each population＇s median lies. Ap combines many desirable features of other distance metrics into a single metric; namely, compared to other metrics, p is relatively insensitive to unequal variances and sample sizes among the populations sam- pied. Furthermore, a key feature of Ap--and our main motivation for developing it--is that it easily accommodates simultaneous comparisons of any number of traits across any number of populations. To exemplify its utility, we employ Ap to address a ques- tion related to the role of sexual selection in speciation： are sexual signals more divergent than ecological traits in closely related taxa？ Using traits of known function in closely related populations, we show that traits predictive of reproductive performance are indeed, more divergent and more sexually dimorphic than traits related to ecological adaptation [Current Zoology 58 （3）： 426-439 2012].

关键词： Effect size Phenotype divergence sexual dimorphism sexual selection speciation

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拼盘·影像志

网球大师 2015年第2期 26-33页

作者： Felix derek

迈阿密，小威廉姆斯参加由自己的基金会主办的极限慈善长跑活动，本来她报名了1／4马拉松，殊不知根本跑不完，最后让保镖背着跑才撞线。60-j布扎比，参加网球邀请赛首轮轮空的纳达尔，忙里偷闲参观了沃尔沃帆船基地。纳达尔生长在西班... 详细信息

迈阿密，小威廉姆斯参加由自己的基金会主办的极限慈善长跑活动，本来她报名了1／4马拉松，殊不知根本跑不完，最后让保镖背着跑才撞线。60-j布扎比，参加网球邀请赛首轮轮空的纳达尔，忙里偷闲参观了沃尔沃帆船基地。纳达尔生长在西班牙海岛马略卡，休赛期也爱驾船出海。

关键词：影像威廉姆斯纳达尔迈阿密基金会马拉松邀请赛沃尔沃

关于“洋脊俯冲作用运动学及其对地幔上涌作用性质指示意义”的讨论

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地质科学译丛 1995年第3期12卷 21-23页

作者： derek j.Thorkelson 张春福 Canada-Yukon Geoscience Office Box 2703. Whitehorsc YI YIA 2C6. Canada

0 引言 ***和***在最近一篇关于“洋脊俯冲作用”论文中,讨论了被淹海底扩张中心的构造、岩浆作用问题。他们的论文汇集了几个洋脊-海沟碰撞带的有用的信息,并且阐明了一种所谓“离析作用”(eduction)的板块作用类型。但是,他们的分析... 详细信息

0 引言 ***和***在最近一篇关于“洋脊俯冲作用”论文中,讨论了被淹海底扩张中心的构造、岩浆作用问题。他们的论文汇集了几个洋脊-海沟碰撞带的有用的信息,并且阐明了一种所谓“离析作用”(eduction)的板块作用类型。但是,他们的分析存在许多缺陷,因为他们:(1)没有考虑俯冲板块和介于其间的板块窗口的几何形状;(2)没有正确表达板块窗口对仰冲板块中的构造、岩浆作用和对地幔流的重要性;(3)不正确地把板块窗口形成的概念和“

关键词：洋脊俯冲作用运动学地幔上涌作用地幔流

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Probability Models of Fire Risk Based on Forest Fire Indices in Contrasting Climates over China

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journal of Resources and Ecology 2012年第2期3卷 105-117页

作者：李晓炜傅国斌 Melanie j. B. ZEPPEL 于秀波赵刚 derek EAMUs 于强中国科学院地理科学与资源研究所陆地水循环及地表过程重点实验室北京100101 中国科学院研究生院北京100049 澳大利亚联邦科学与工业研究组织(CsIRO)土地与水资源处麦考瑞大学生物科学系中国科学院地理科学与资源研究所生态系统网络观测与模拟重点实验室北京100101 悉尼科技大学环境学院

Fire weather indices have been widely applied to predict fire risk in many regions of the world. The objectives of this study were to establish fire risk probability models based on fire indices over different climatic regions in China. We linked the indices adopted in Canadian, Us, and Australia with location, time, altitude, vegetation and fire characteristics during 1998-2007 in four regions using semi- parametric logistic （sPL） regression models. Different combinations of fire risk indices were selected as explanatory variables for specific regional probability model. sPL regression models of probability of fire ignition and large fire events were established to describe the non-linear relationship between fire risk indices and fire risk probabilities in the four regions. Graphs of observed versus estimated probabilities, fire risk maps, graphs of numbers of large fire events were produced from the probability models to assess the skill of these models. Fire ignition in all regions showed a significant link with altitude and NDVI. Indices of fuel moisture are important factors influencing fire occurrence in northern China. The fuel indices of organic material are significant indicators of fire risk in southern China. Besides the well skill of predicting fire risk, the probability models are a useful method to assess the utility of the fire risk indices in estimating fire events. The analysis presents some of the dynamics of climate-fire interactions and their value for management systems.

关键词： climate forest fire meteorological risk fire risk indices semi-parametric logistic regression model

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