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Refining biome labeling for large-scale microbial community samples:Leveraging neural networks and transfer learning

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Environmental science and Ecotechnology 2024年第1期17卷 128-137页

作者： nan Wang Teng Wang Kang Ning Key Laboratory of Molecular Biophysics of the Ministry of Education Hubei Key Laboratory of Bioinformatics and Molecular-imagingCenter of AI BiologyDepartment of Bioinformatics and Systems BiologyCollege of Life Science and TechnologyHuazhong University of Science and TechnologyWuhan430074HubeiChina

Microbiome research has generated an extensive amount of data,resulting in a wealth of publicly accessible *** annotation of these samples is crucial for effectively utilizing microbiome data across scientific ***,a notable challenge arises from the lack of essential annotations,particularly regarding collection location and sample biome information,which significantly hinders environmental microbiome *** this study,we introduce Meta-Sorter,a novel approach utilizing neural networks and transfer learning,to enhance biome labeling for thousands of microbiome samples in the MGnify database that have incomplete *** findings demonstrate that Meta-Sorter achieved a remarkable accuracy rate of 96.7%in classifying samples among the 16,507 lacking detailed biome ***,Meta-Sorter provides precise classifications for representative environmental samples that were previously ambiguously labeled as“Marine”in MGnify,thereby elucidating their specific origins in benthic and water column ***,Meta-Sorter effectively distinguishes samples derived from human-environment interactions,enabling clear differentiation between environmental and human-related *** improving the completeness of biome label information for numerous microbial community samples,our research facilitates more accurate knowledge discovery across diverse disciplines,with particular implications for environmental research.

关键词： Microbial community Transfer learning Sample classification Environmental scientific research Novel knowledge discovery

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High-throughput and simultaneous inertial separation of tumor cells and clusters from malignant effusions using spiral-contraction-expansion channels

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Microsystems & nanoengineering 2024年第2期10卷 91-99页

作者： Zhixian Zhu Hui Ren Dan Wu Zhonghua Ni nan Xiang School of Mechanical Engineering and Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical InstrumentsSoutheast University211189NanjingChina School of Mechanical Technology Wuxi Institute of TechnologyNo.1600 Gaolang West Road214129WuxiChina department of Oncology Jiangyin People’s Hospital214400JiangyinChina

Tumor cell clusters are regarded as critical factors in cancer pathophysiology,and increasing evidence of their higher treatment resistance and metastasis compared to single tumor cells has been ***,existing cell separation methods that are designed for single tumor cells cannot be used to simultaneously purify tumor cell *** address this problem,we demonstrated a microfluidic approach for the high-throughput,continuous-flow ternary separation of single tumor cells,tumor cell clusters,and WBCs from clinical pleural or abdominal effusions by coupling slanted spiral channels and periodic contraction-expansion *** first systematically explored the influence of particle size and flow rate on particle *** separation performance indicated that 94.0%of WBCs were removed and more than 97%of MDA-MB-231 tumor cells were recovered at a high flow rate of 3500µL/***,more than 90%of tumor cell clusters were effectively preserved after ***,we successfully applied our device for the ternary separation of single tumor cells,tumor cell clusters,and WBCs from different malignant effusions collected from patients with metastatic ***,our spiral-contraction-expansion device has potential as a sample pretreatment tool for the cytological diagnosis of malignant effusions.

关键词： separation contraction removed

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Morphology-Tailored Dynamic State Transition in Active-Passive Colloidal Assemblies

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Research 2024年第3期2024卷 751-760页

作者： nan Yu Zameer H.Shah Mingcheng Yang Yongxiang Gao Institute for Advanced Study Shenzhen University518060ShenzhenChina Key Laboratory of Optoelectronic Device and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen University518060ShenzhenChina Beijing National Laboratory for Condensed Matter Physics and Laboratory of Soft Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical sciences University of Chinese Academy of SciencesBeijing 100049China Songshan Lake Materials Laboratory DongguanGuangdong 523808China.

Mixtures of active self-propelled and passive colloidal particles promise rich assembly and dynamic states that are beyond reach via equilibrium ***,controllable transition between different dynamic states remains ***,we reveal a plethora of dynamic behaviors emerging in assemblies of chemically propelled snowman-like active colloids and passive spherical particles as the particle shape,size,and composition are *** example,assembles of one or more active colloids with one passive particle exhibit distinct translating or orbiting states while those composed of one active colloid with 2 passive particles display persistent“8”-like cyclic motion or hopping between circling states around one passive particle in the plane and around the waist of 2 passive ones out of the plane,controlled by the shape of the active colloid and the size of the passive particles,*** morphology-tailored dynamic transitions are in excellent agreement with state diagrams predicted by mesoscale dynamics *** work discloses new dynamic states and corresponding transition strategies,which promise new applications of active systems such as micromachines with functions that are otherwise impossible.

关键词： Transition otherwise transitions

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Epidemic dynamics on complex networks

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Progress in Natural science:Materials International 2006年第5期16卷 452-457页

作者： ZHOU Tao , FU Zhongqian, and WANG Binghong (department of Electronic science and Technology, university of science and Technology of china, Hefei 230026, china department of Modern Physics, university of science and Technology of china, Hefei 230026, china) [a]department of Electronic science and Technology University of Science and Technology of China Hefei China

Recently, motivated by the pioneer work in revealing the small-world effect and scale-free property of various real-life networks, many scientists devote themselves to studying complex networks. One of the ultimate goals is to understand how the topological structures affect the dynamics upon networks. In this paper, we give a brief review on the studies of epidemic dynamics on complex networks, including the description of classical epidemic models, the epidemic spread on small-world and scale-free networks, and network immunization. Finally, perspectives and some interesting problems are proposed.

关键词： epidemic dynamics complex networks critical value immunization small-world effect scale-free property.

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Fabrication of a 25.2 T NMR magnet for an extreme condition user facility in china

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National science Review 2024年第7期11卷 62-64页

作者： Hui Han yun Shang MRI Research Institute Department of RadiologyWeill Medical College of Cornell University

An ultra-high field magnet（>20 T）is desirable for studying the characteristics of new materials under extreme magnetic conditions [1]. Additionally,such field strength will result in resonance frequencies close to or greater than 1 GHz when applied to the study of1H signals from biomolecules by nuclear magnetic resonance（NMR）,which will lead to a higher signal-to-noise ratio, better sensitivity and a higher spectral resolution due to increased chemical shift dispersion [2].

关键词： NMR double pancake high temperature superconducting magnet ultra-high field

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Wave Solutions for the GinzburgLandau-BBM Equations (I)

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Communications in Nonlinear science and Numerical Simulation 1998年第4期3卷 218-221页

作者： Murong JIANG and Yawei TIAN(department of Mathematics, yunnan university, kunming 650091, china)(Graduate School of china Academy of Engineering and Physics, P.O.Box 2010 Beijing100081, china)(Computer department, Shaanxi Normal university, Xi’an 710062, department of Mathematics Yunnan University Kunming 650091 China Graduate School of china Academy of Engineering and Physics P.O.Box 2010 Beijing 100081 China Computer department Shanxi Normal University Xi'an 710062 China

In this paper, the stability of plane wave solutions for the GinzburgLandau-BBM equations are considered. When the coefficients are suitably constrained,these waves are stable.

关键词： stability the Ginzburg- Landau- BBM equations plane wave solutions

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TYPE X MONOTONE SYSTEMS WITH AN ORDER-INCREASING INVARIANT FUNCTION

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Chinese Annals of Mathematics,Series B 1996年第3期17卷 335-342页

作者： JIANG JIFA(department of Mathematics, The university of science and Technology of china, Hefei 230036, china.) department of Mathematics University of Science and Technology of China Hefei 230036 China

The author considers the asymptotic behavior of solutions of a class of ordinary dmerentialequations x = F(x) in the nonnegative orthant R7. Suppose that F(o) = o, Fi(x1,..., xn) isnondecreasing in xk for all k≠ i and that F possesses an order-increasing invarian *** it is shown that every bounded solution to such a system converges to a single equilibrium.

关键词： Type K monotone system Monotone flow Invariant function Equilibrium Convergence

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Laser-field-induced magnon amplification in a magnetic semiconductor quantum well under an external magnetic field

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Journal of university of science and Technology Beijing 2003年第5期10卷 69-72页

作者： Peng FengPhysics department, university of science and Technology Beijing, Beijing 100083, china Phys. Dept. Univ. of Sci. and Technol. Beijing Beijing 100083 China

The laser-field induced magnon amplification in a magnetic semiconductorquantum well under an external magnetic field was discussed, it is shown that when the laserfrequency is near to the electron cyclotron frequency, no matter how weaker the laser field is, themagnon amplification always occurs. In case of fixed laser frequency, the optical absorption ofmagnons obeys the definite selection rule to the laser field strength. The rate of change of magnonoccupation is calculated, and the amplification condition is given.

关键词： magnon amplification magnetic semiconductor quantum well laser field

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REACTION MECHANISM OF BENZOPHENONE-PHOTOINITIATED CROSSLINKING OF POLYETHYLENE

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Chinese Journal of Polymer science 2002年第4期20卷 291-307页

作者： Bao-jun Qu State Key Laboratory of Fire science and department of Polymer science and Engineering university of science and Technology of china Hefei 230026 china Univ Sci & Technol china State Key Lab Fire Sci Hefei 230026 Peoples R China Univ Sci & Technol china Dept Polymer Sci & Engn Hefei 230026 Peoples R China

The radical intermediates, the crosslink microstructures, and the reaction mechanism of benzophenone (BP)-photoinitiated crosslinking of low-density polyethylene (LDPE) and model compounds (MD) have been reviewed in detail. The spin-trapping electron spin resonance (ESR) spectra obtained from the LDPE/BP systems with spin-trap agents show that two kinds of polymer radical intermediates are mainly formed: tertiary carbon and secondary carbon radicals. The spin-trapping ESR studies of MD/BP systems give further evidence that photocrosslinking reactions of PE predominantly take place a sites of tertiary carbon, secondary carbon, and especially allylic carbon when available. The high resolution C-13-NMR spectra obtained from LDPE and MD systems show that the crosslink microstructures have H- and Y-type links and that their concentrations are of the same order. The fluorescence, ESR, C-13 and H-1-NMR spectra from the PE and MD systems demonstrate that the main photoreduction product of BP (PPB) is benzpinacol formed by the recombination of two diphenylhydroxymethyl (K-.) radical intermediates. Two new PPB products: an isomer of benzpinacol with quinoid structure, 1-phenylhydroxymethylene-4-diphenylhydroxymethyl-2,5-cyclobexadiene and three kinds of alpha-alkyl-benzhydrols have been detected and identified. These results provide new experimental evidence for elucidating the reaction mechanism in the BP-photoinitiated crosslinking of polyethylene.

关键词： photocrosslinking mechanism polymer radical intermediates crosslink microstructures photolytic products of benzophenone polyethylene model compound

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Stability of Plane Wave Solutions for the Ginzburg-Landau-BBM Equations (II)

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Communications in Nonlinear science and Numerical Simulation 1999年第1期4卷 68-71页

作者： Murong JIANG (department of Mathematics, yunnan university, kunming 650091, china) (Graduate School of china Academy of Engineering and Physics, P.O.Box 2101, Beijing, china) E-mail. jiangmr@*** department of Mathematics Yunnan University Kunming 650091 China Graduate School of china Academy of Engineering and Physics P.O.Box 2101 Beijing China

In part (I) of this paper, the stability of plane waves for the GinzburgLandau-BBM equations has been proved. Here, the perturbation decays are obtained by using the Fourier transformation and semigroup estimates.

关键词： decay estimates semigroup the Ginzburg-Landau-BBM equations

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