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Digestive system involvement and clinical outcomes among COVID-19 patients:A retrospective cohort study from Qatar

World Journal of Gastroenterology 2021年第46期27卷 7995-8009页

作者： Muhammad Umair Khan Kamran Mushtaq deema hussam.alsoub Phool Iqbal Fateen Ata Hammad Shabir Chaudhry Fatima Iqbal Girisha Balaraju Muna A Al Maslamani Betsy Varughese Rajvir Singh Khalid Al Ejji Saad Al Kaabi Yasser Medhat Kamel Adeel Ajwad Butt Department of Gastroenterology and Hepatology Hamad Medical CorporationDoha 3050Qatar ECPEExecutive and Continuing Professional Education Harvard T.H Chan School of Public HealthBostonMA 02115-5810United States Department of Palliative Care National Center for Cancer Care&ResearchHamad Medical CorporationDoha 3050Qatar Department of Medicine Hamad Medical CorporationDoha 3050Qatar Department of Infectious Disease Communicable Disease CenterHamad Medical CorporationDoha 3050Qatar Department of Cardiology Research Heart HospitalHamad Medical CorporationDoha 3050Qatar Department of Medicine Division of Infectious DiseasesWeill Cornell Medical CollegeNew YorkNY 10075United States Department of Medicine Weill Cornell Medical College-QatarDoha 24144Qatar

BACKGROUND Coronavirus disease 2019(COVID-19)caused by the severe acute respiratory syndrome coronavirus 2 virus most commonly presents with respiratory *** gastrointestinal(GI)manifestations either at presentation or during hospitalization are also common,their impact on clinical outcomes is *** studies have described worse outcomes in COVID-19 patients with GI symptoms,while others have shown either no association or a protective *** is a need for consistent standards to describe GI symptoms in COVID-19 patients and to assess their effect on clinical outcomes,including mortality and disease *** To investigate the prevalence of GI symptoms in hospitalized COVID-19 patients and their correlation with disease severity and clinical *** We retrospectively reviewed 601 consecutive adult COVID-19 patients requiring hospitalization between May 1-15,*** symptoms were recorded at admission and during ***,clinical,laboratory,and treatment data were *** outcomes included all-cause mortality,disease severity at presentation,need for intensive care unit(ICU)admission,development of acute respiratory distress syndrome,and need for mechanical *** logistic regression model was used to identify independent predictors of the adverse *** The prevalence of any GI symptom at admission was 27.1%and during hospitalization was 19.8%.The most common symptoms were nausea(98 patients),diarrhea(76 patients),vomiting(73 patients),and epigastric pain or discomfort(69 patients).There was no difference in the mortality between the two groups(6.21%vs 5.5%,P=0.7).Patients with GI symptoms were more likely to have severe disease at presentation(33.13%vs 22.5%,P<0.001)and prolonged hospital stay(15 d vs 14 d,P=0.04).There was no difference in other clinical outcomes,including ICU admission,development of acute respiratory distress syndrome,or need for mechanical ventil

关键词： COVID-19 Gastrointestinal manifestations Mortality Intensive care unit admission Mechanical ventilation Disease severity

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Speckle-interferometric Study of Close Visual Binary System HIP 11253(HD 14874)using Gaia(DR2 and EDR3)

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Research in Astronomy and Astrophysics 2023年第7期23卷 221-228页

作者： hussam Aljboor Ali Taani Department of Basic Scientific Sciences Prince Hussein Bin Abdullah Ⅱ Academy for Civil ProtectionAl Balqa Applied UniversityAmmanJordan Physics Department Faculty of ScienceAl Balqa Applied University19117 SaltJordan

We present a comprehensive set of physical and geometrical parameters for each of the components of the close visual binary system HIP 11253(HD 14874).We present an analysis for the binary and multiple stellar systems with the aim to obtain a match between the overall observational spectral energy distribution of the system and the spectral synthesis created from model atmospheres using Al-Wardat's method for analyzing binary and multiple stellar *** epoch positions are used to determine the orbital parameters and the total *** parameters of both components are derived as:T_(eff)^(a)=6025,T_(eff)^(b)=4710,logg_(a)=4.55,logg_(b)=4.60,R_(a)=1.125 R_(⊙),R_(b)=0.88R_(⊙),L_(a)=1.849 L_(⊙),L_(b)=0.342 L_(⊙).Our analysis shows that the spectral types of the components are F9 and *** combining the orbital solution with the parallax measurements of Gaia DR2 and EDR3,we estimate the individual masses using the H-R diagram as M_(a)=1.09 M_(⊙)and M_(b)=0.59 M_(⊙)for using Gaia DR2 parallax and M_(a)=1.10 M_(⊙)and M_(b)=0.61 M_(⊙)for using Gaia EDR3 ***,the location of both system's components on the stellar evolutionary tracks is presented.

关键词： (stars:)binaries:visual stars:kinematics and dynamics (stars:)binaries(including multiple):close techniques:interferometric techniques:spectroscopic

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Physical and orbital properties of the stellar system HIP 43766

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Research in Astronomy and Astrophysics 2021年第5期21卷 84-90页

作者： Hatem Widyan hussam Aljboor Department of Physics Al al-Bayt UniversityMafraq 25113Jordan

In this paper,we present the analysis of the stellar binary system HIP 43766 to determine its *** rely on dynamical modeling and atmospheric modeling with recent data to determine the orbital solution and the physical properties of the *** is a consistency between observed and synthetic photometry obtained using atmospheric *** calculated dynamical mass sum of the system ranged between 1.691 and 2.609 solar masses,while it ranges between 2.0 and 2.1 as estimated utilizing atmospheric *** could be due to inaccuracy in estimating the orbit,which could be modified with future observations with more relative positional *** parameters of the system and the position of the components on the evolutionary tracks show that the system consists of F5 and G5 subgiant stars,mostly formed by fragmentation.A dynamical mass sum is predicted for the system.

关键词： stars:binaries:close stars:binaries:visual stars:individual:HIP 43766

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Seismic Analysis of Reinforced Concrete Silos under Far-Field and Near-Fault Earthquakes

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Structural Durability & Health Monitoring 2022年第3期16卷 213-233页

作者： Anwer H.Hussein hussam K.Risan Department of Civil Engineering Al-Nahrain UniversityBaghdad10072Iraq

Silos are strategical structures used to stockpile various types of granular *** are highly vulnerable to earthquake excitation and have been frequently reported to fail at a higher rate than any other industrial *** seismic response of silos within the near-fault region will suffer a complex combination of loadings due to the unique characteristics of the near-fault ground motions;which are usually associated with a large amplitude pulse at the beginning of either the velocity or the displacement time *** study aims to numerically evaluate the seismic response of reinforced concrete cylindrical silos under near-fault ground motions(NFGM)and far-field ground motions(FFGM).The assessment investigates the impact of the slenderness ratio and the para-meters’influence on the seismic behavior of reinforced concrete *** validity of the Eurocode provisions in the structural safety of silos will also be *** nonlinear time history analysis is carried out through the finite element approach by examining four silos with different slenderness *** concrete damage plas-ticity model is assigned to the silo wall to simulate the nonlinear behavior of concrete in the plastic zone;while,the behavior of the stored material is represented by the Drucker-Prager plastic *** wall-granular material interaction is considered and defined by coulomb’s friction *** results of the near-fault records reveal a growth up to 72.8%in the hoop stress and 160.4%in the vertical stress compared to the far-field ***,the seismic response of reinforced concrete silos is highly sensitive to the type of ground motion,and slender silos tend to impose greater structural demand under the ***,The Eurocode-8 seismic provisions were adequate in the conventional far-field ground motions and less effective in the near-fault zone.

关键词： Silos seismic analysis near-fault earthquake far-field earthquake

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IoMT-Based Smart Healthcare of Elderly People Using Deep Extreme Learning Machine

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Computers, Materials & Continua 2023年第7期76卷 19-33页

作者： Muath Jarrah hussam Al Hamadi Ahmed Abu-Khadrah Taher M.Ghazal School of Information Technology Skyline University CollegeUniversity City Sharjah1797SharjahUAE College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia Center for Cyber Security Faculty of Information Science and TechnologyUniversity Kebangsaan Malaysia(UKM)43600BangiSelangorMalaysia Center for Cyber-Physical Systems Khalifa University127788Abu DhabiUAE

The Internet of Medical Things(IoMT)enables digital devices to gather,infer,and broadcast health data via the cloud *** phenomenal growth of the IoMT is fueled by many factors,including the widespread and growing availability of wearables and the ever-decreasing cost of sensor-based *** is a growing interest in providing solutions for elderly people living assistance in a world where the population is rising *** IoMT is a novel reality transforming our daily *** can renovate modern healthcare by delivering a more personalized,protective,and collaborative approach to ***,the current healthcare system for outdoor senior citizens faces new *** healthcare systems are inefficient and lack user-friendly technologies and interfaces appropriate for elderly people in an outdoor ***,in this research work,a IoMT based Smart Healthcare of Elderly people using Deep Extreme Learning Machine(SH-EDELM)is proposed to monitor the senior citizens’*** performance of the proposed SH-EDELM technique gives better results in terms of 0.9301 accuracy and 0.0699 miss rate,respectively.

关键词： ICT ML FN DELM SH-EDELM

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Bone mineral density in fracture neck of femur patients:What's the significance?

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World Journal of Orthopedics 2022年第2期13卷 160-170页

作者： hussam Elamin Ahmed Oday Al-Dadah Department of Trauma and Orthopaedic Surgery South Tyneside District HospitalHarton LaneSouth Tyneside NE340PLUnited Kingdom Translational and Clinical Research Institute Faculty of Medical SciencesNewcastle UniversityNewcastle-upon-Tyne NE24HHUnited Kingdom

BACKGROUND The National Institute for Health and Care Excellence(NICE)guidelines have advised further research is required into investigating the added prognostic value of bone mineral density(BMD)in the assessment of fracture risk with the Fracture Risk Assessment Tool(FRAX)*** To investigate the significance of BMD in fracture neck of femur patients and compare it to the outcome of the FRAX *** Inclusion criteria for this study were all patients who underwent dual-energy Xray absorptiometry(DXA)scan following fracture neck of femur between 2015 and *** of BMD,FRAX scores and patient demographic data was *** A total of 69 patients were included in the study,mean age 74.1 *** was no significant difference between mean BMD of the femoral neck in males(0.65)as compared to females(0.61)(P=0.364).Analyses showed no significant correlation between BMD and menopause age(rs=-0.28,P=0.090).A significant difference was seen of the femoral neck BMD between the different fracture pattern types(P=0.026).A stronger correlation was observed between BMD of femoral neck and FRAX major score(rs=-0.64,P<0.001)than with BMD of lumbar spine and FRAX major score(rs=-0.37,P=0.003).CONCLUSION This study demonstrated that BMD of the femoral neck measured by DXA scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system.

关键词： Fracture neck of femur Bone mineral density Fracture Risk Assessment Tool score Fragility fracture Osteoporosis

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L-Carnitine, but not coenzyme Q10, enhances the anti-osteoporotic effect of atorvastatin in ovariectomized rats

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2016年第1期17卷 43-53页

作者： hussam A.S.MURAD Department of Pharmacology Faculty of MedicineRabighKing Abdulaziz University Department of Pharmacology Faculty of MedicineAin Shams University

Objective： Statins＇ therapy in osteoporosis can aggravate muscle damage. This study was designed to assess which agent, L-carnitine or coenzyme Q10, could enhance the anti-osteoporotic effect of atorvastatin while antagonizing myopathy in ovariectomized rats. Methods： Forty-eight female Sprague Dawley rats were used; forty rats were ovariectomized while eight were sham-operated. Eight weeks post-ovariectomy, rats were divided into ovariectomized-untreated group and four ovadectomized-treated groups （n=8） which received by gavage （mg/（kg.d）, for 8 weeks） 17^-estradiol （0.1）, atorvastatin （50）, atorvastatin （50）＋L-carnitine （100）, or atorvastatin （50）＋coenzyme Q10 （20）. At the end of therapy, bone mineral density （BMD）, bone mineral content （BMC）, and serum levels of bone metabolic markers （BMMs） and creatine kinase （CK） were measured. Femurs were used for studying the breaking strength and histopathological changes. Results： Treatment with atorvastatin＋L-carnitine restored BMD, BMC, and bone strength to near normal levels. Estrogen therapy restored BMD and BMC to near normal levels, but failed to increase bone strength. Although atorvastatin and atorvastatin＋coenzyme Q10 improved BMD, BMC, and bone strength, they failed to restore levels to normal. All treatments decreased BMMs and improved histopathological changes maximally with atorvastatin＋L-carnitine which restored levels to near normal. Atorvastatin aggravated the ovariectomy-induced increase in CK level while estrogen, atorvastatin＋L-carnitine, and atorvastatin＋coenzyme Q10 decreased its level mainly with atorvastatin＋L-camitine which restored the level to near normal. Conclusions： Co- administration of L-carnitine, but not coenzyme Q10, enhances the anti-osteoporotic effect of atorvastatin while an- tagonizing myopathy in ovariectomized rats. This could be valuable in treatment of osteoporotic patients. However, further confirmatory studies are needed.

关键词： Atorvastatin Coenzyme Q10 L-Carnitine Ovariectomized

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Morphology and Histochemistry of Infralabial Glands of Two Species in the Slug-Eating Family Pareidae(Reptilia:Serpentes)

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Asian Herpetological Research 2022年第3期13卷 180-189页

作者： Dan WANG Jinlong REN Ke JIANG Wei WU Changjun PENG hussam ZAHER Dechun JIANG Jiatang LI CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan ProvinceChengdu Institute of BiologyChinese Academy of SciencesChengdu 610041SichuanChina University of Chinese Academy of Sciences Beijing 100049China Museu de Zoologia Universidade de Sao PauloSao Paulo 04263-000SPBrazil Southeast Asia Biodiversity Research Institute Chinese Academy of SciencesYezinNay Pyi Taw 05282Myanmar

Pareidae and Dipsadidae,two independently evolved taxa in the Serpentes lineage,both feed exclusively on terrestrial mollusks(snails and slugs).Dipsadid snakes developed hypertrophic infralabial glands in their lower jaw,which are thought to be associated with their specialized feeding ***,whether a similar gland exists in pareid snakes is *** this study,we examined the morphological characteristics of the infralabial glands in Pareas berdmorei and Pareas chinensis based on comparative anatomical,histochemical,and histopathological *** results demonstrated that both Pareas species had similar hypertrophied infralabial glands in the lower jaw,which consisted of tubules with mucinous properties and seromucous *** secretory granules of the seromucous cells also showed high electron *** cytoplasm was rich in rough endoplasmic reticulum,mitochondria,and Golgi apparatus,suggesting that these cells may secrete protein substances,and play an important role in digesting *** study provides evidence of morphological convergence between Pareidae and Dipsadidae due to specialized diet adaptation,which will be the foundation for prospective functional research.

关键词： convergent evolution histology Pareas berdmorei pareas chinensis specialized diet

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In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass

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Cardiovascular Innovations and Applications 2020年第4期5卷 139-143页

作者： Nathan Burke Tawanna Charlton hussam Hawamdeh Ki Park Division of Cardiovascular Medicine University of Florida College of MedicineGainesvilleFloridaUSA

In-stent thrombosis(IST)is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization *** is a case of an 81-year-old man who presented with ST-elevation myocardial *** coronary artery(RCA)occlusion was *** angiography and percutaneous coronary intervention were *** left coronary artery disease was subsequently *** cardiothoracic surgeon request,the patient was transitioned from ticagrelor to clopidogrel therapy in preparation for coronary artery bypass *** patient experienced IST the day before surgery while receiving *** examine this case,which highlights the complexity of antiplatelet therapy choice and the role of genetic testing in evaluation of IST risk.

关键词： Acute myocardial infarction/ST-elevation myocardial infarction antiplatelet therapy genetics platelet biology drug-eluting stent drugs/pharmacotherapy

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Catheter ablation using pulsed-field energy:Do we finally have the magic wand to defeat atrial fibrillation?

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World Journal of Cardiology 2024年第12期16卷 677-682页

作者： Ernesto Cristiano hussam Ali Eduardo Celentano Riccardo Cappato Department of Cardiac Electrophysiology Complex Operational Unit Humanitas GavazzeniBergamo 24125LombardyItaly Arrhythmia and Electrophysiology Center IRCCS MultiMedicaSesto San Giovanni 20099MilanItaly Department of Cardiology Erasmus University Medical CenterRotterdam 3090Netherlands

Clinical outcomes of catheter ablation remain suboptimal in patients with atrial fibrillation(AF),particularly in those with persistent AF,despite decades of research,clinical trials,and technological ***,pulsed-field ablation(PFA),a promising non-thermal technology,has been introduced to improve procedural *** unique feature of myocardial selectivity offers safety advantages by avoiding potential harm to vulnerable adjacent structures during AF ***,despite the global enthusiasm within the electro-physiology community,recent data indicate that PFA is still far from being a“magic wand”for addressing such a complex and challenging arrhythmia as *** progress is needed in mapping processes rather than in ablation *** editorial reviews relevant available data and explores future research directions for PFA.

关键词： Atrial fibrillation Pulsed field ablation Radiofrequency ablation Elec-troporation Electroanatomic mapping Catheter ablation Interventional cardiology Cardiac arrhythmias

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