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Inhibitor-Based Therapeutics for Treatment of Viral Hepatitis

Journal of Clinical and Translational Hepatology 2016年第3期4卷 248-257页

作者： debajit dey Manidipa Banerjee Kusuma School of Biological Sciences Indian Institute of Technology Delhi Hauz Khas New Delhi India

Viral hepatitis remains a significant worldwide threat,in spite of the availability of several successful therapeutic and vaccination *** associated with acute and chronic infections,such as liver failure,cirrhosis and hepatocellular carcinoma,are the cause of considerable morbidity and *** the significant burden on the healthcare system caused by viral hepatitis,it is essential that novel,more effective therapeutics be *** present review attempts to summarize the current treatments against viral hepatitis,and provides an outline for upcoming,promising new *** of novel therapeutics requires an understanding of the viral life cycles and viral effectors in molecular *** such,this review also discusses virallyencoded effectors,found to be essential for virus survival and replication in the host milieu,which may be utilized as potential candidates for development of alternative therapies in the future.

关键词： viral hepatitis Viroporin Inhibitor

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How Does the Blue C Stock Vary in Restored and Degraded Wetlands Across Land Cover Mosaics? Evidences from Medinipur Coastal Plain, India

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Journal of Resources and Ecology 2024年第4期15卷 898-908页

作者： Mansa dey Mrinmoyee NASKAR Sohini NEOGY debajit DATTA Landscape Ecology Laboratory Department of GeographyJadavpur UniversityKolkata 700032India Department of Geography Baruipur CollegeBaruipur 743610India Department of Geography Banwarilal Bhalotia CollegeAsansol 713303India

Coastal wetlands are of paramount importance as major reservoirs of blue carbon(C),playing a crucial role in providing nature-based solutions to mitigate climatic *** research aimed to analyse the dynamics of total blue C(TBC)and its components;*** organic C(SOC),below ground C,and above ground C;as well how they are influenced by land use/land cover(LULC)categories and wetland ***,study were identified as one restored wetland and another degraded wetland in the Medinipur Coastal Plain,*** LULC categories were analyzed using Pleiades 1A and 1B satellite imagery,corresponding to the restored and degraded wetland,*** quantification of SOC was based on point-specific sample data collected from both wetlands(nr=250;nd=84).Above ground biomass(AGB)was appraised employing allometric relationships involving field-measured dendrometric *** ground biomass values were calculated using indirect allometric equations that take into account the AGB *** all the components,TBC stock of the restored and degraded wetlands were estimated at 246710.91 Mg and 7865.49 Mg,*** the restored wetland,dense mangrove and open mangrove exhibited higher concentrations of blue C components,while other LULC categories demonstrated moderate to low *** the degraded wetland,the open mangrove category rechigh densities of C pools,whereas herbaceous vegetation,bare earth and sand,and waterbody exhibited lower *** results portrayed significant disparities(P<0.05)in blue C pools among different LULC categories in both ***,it was evident that wetland type and LULC category had notable(P<0.001)impacts on TBC dynamics,both individually and in ***,this research may aid in effective management of coastal wetlands as blue C sinks,emphasizing their significance as essential elements of climate mitigation strategies.

关键词： blue C pools coastal wetland dendrometric variable landscape transformation mangrove plantation wetland restoration

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Spatially explicit estimation of soil organic carbon stock of an estuarine mangrove wetland of eastern India using elemental analysis and very-fine resolution satellite data

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Ecological Processes 2022年第1期11卷 411-426页

作者： debajit Datta Madhumita Bairagi Mansa dey Argha Pratim Pal Jibananda Gayen Department of Geography Jadavpur UniversityKolkata 700032India Department of Geography Sree Chaitanya CollegeHabra 743268India

Background:This study estimated the total soil organic C(SOC)stock of the wetland influence zone of Bichitrapur mangroves in eastern India in a spatially explicit *** spatial and vertical distribution of SOC densities with respect to land use/land cover(LULC)pattern were ***,some site-specific management strate-gies were forwarded towards enhancement of C sequestration ***:The changing patterns of LULC within the wetland influence zone of the site were analyzed using Landsat TM(30 m)and Pleiades-1A(2 m)imageries from 1988 to ***-specific SOC measurement was done using samples taken from four core-depth intervals(viz.D1:0–20 cm,D2:20–40 cm,D3:40–70 cm,D4:70–100 cm)at 89 locations belonging to different LULC *** interpolation was applied on this point-based data to produce SOC density and stock models as a whole and at all *** between SOC density,core-depth and present LULC were evaluated through multivariate statistical ***:The LULC transformations during last three decades suggested the gradual growth of mangrove plantations as well as agricultural and aquacultural *** amount of SOC was concentrated in D1(37.17%)followed by D3(26.51%),while D4 had the lowest(10.87%).The highest mean SOC density was observed in the dense mangrove patches(248.92 Mg ha^(−1))and the lowest mean was in the Casuarina plantations(2.78 Mg ha^(−1)).Here,Spline method emerged as the best-fit interpolation technique to model SOC data(R^(2)=0.74)and estimated total SOC stock of the entire wetland influence zone as 169,569.40 Mg and the grand mean as 125.56 Mg ha^(−1).Overall,LULC was inferred as a major determinant of SOC dynamics with a statistically significant effect(p<0.001),whereas no such inference could be drawn for soil ***:The C sequestration potential of sites such as the present one could be increased with appropriate zone-wise plantation strategies,restrict

关键词： Blue C density Core-depth Coastal wetland Dry combustion Land use conversion Wetland influence zone

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