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Thermal conductivity suppression in uranium-doped thorium dioxide due to phonon-spin interactions

Journal of Materiomics 2024年第3期10卷 709-715页

作者： Zilong Hua Saqeeb Adnan Amey R.Khanolkar Karl Rickert david B.Turner Timothy A.prusnick J.Matthew Mann david H.Hurley Marat Khafizov Cody A.Dennett Materials Science and Engineering Department Idaho National LaboratoryIdaho FallsID83415USA Department of Mechanical and Aerospace Engineering The Ohio State UniversityColumbusOH43210USA KBR DaytonOH45431USA Azimuth Corporation FairbornOH45324USA Air Force Research Laboratory Wright-Patterson AFBOH45433USA Department of Nuclear Science and Engineering Massachusetts Institute of TechnologyCambridgeMA02139USA

In this work,impact of low level of uranium(U)atom substitution on thermal conductivity of thorium dioxide(ThO_(2))is ***_(2)is an electronic insulator with a wide optical band-gap and no unpaired electrons whose thermal transport is governed by phonons.U-substitution introduces unpaired f-electrons resulting in paramagnetic behavior of UeThO_(2)at room temperature,which significantly suppresses its thermal conductivity.A single crystal of UeThO_(2)with graded composition of U is grown using a hydrothermal synthesis method,and thermal conductivity measurements are performed in re-gions with uniform composition of U at levels of 0%,6%,9%and 16%.Measured thermal conductivity profiles over 77e300 K temperature range are analyzed using an analytical expression for phonon-mediated thermal transport based on Klemens-Callaway *** dependent thermal con-ductivity is found to deviate significantly from the Rayleigh scattering trend expected for a simple substitutional point defect with a small perturbation to mass and interatomic *** the resonant scattering term,observed large suppression of thermal conductivity at low temperatures can be closely ***,the extracted phonon-spin coupling constants imply a nonlinear relation of phonon-spin interaction intensity with respect to U doping *** study reveals how phonon-spin scattering contributed by unpaired f-electrons in U atoms influences thermal transport in the UeThO_(2)system.

关键词： phonon-spin interactions Thermal conductivity UdThO_(2)system

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Acceptor doping and actuation mechanisms in Sr-doped BiFeO_(3)-BaTiO_(3)ceramics

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Journal of Materiomics 2024年第1期10卷 57-69页

作者： Ziqi Yang Yizhe Li Bing Wang Juncheng pan Annette K.Kleppe david A.Hall Department of Materials University of ManchesterM139PLManchesterUK Diamond Light Source Ltd. Harwell Science and Innovation CampusOX110DEDidcotUK

BiFeO_(3)-BaTiO_(3)(BF-BT)ceramics are important multiferroic materials,which are attracting significant attention for potential applications in high temperature lead-free piezoelectric *** the present study,the effects of Sr^(2+)as an acceptor dopant for Bi^(3+),in the range from 0 to 1.0%(in mole),on the structure and ferroelectric/piezoelectric properties of 0.7BiFeO_(3)-0.3BaTiO_(3)ceramics were *** use of a post-sintering Ar annealing process was found to be an effective approach to reduce electrical conductivity induced by the presence of electron holes associated with reoxidation during cooling.A low Sr dopant concentration(0.3%,in mole)yielded enhanced ferroelectric(p_(max)∼0.37 C/m^(2),p_(r)∼0.30 C/m^(2))and piezoelectric(d_(33)∼178 pC/N,k_(p)∼0.27)properties,whereas higher levels led to chemically heterogeneous core-shell structures and secondary phases with an associated decline in *** electric field-induced strain of the Sr-doped BF-BT ceramics was investigated using a combination of digital image correlation macroscopic strain measurements and in-situ synchrotron X-ray *** of the intrinsic(lattice strain)and extrinsic(domain switching)contributions to the electric field induced strain indicated that the intrinsic contribution dominated during the poling process.

关键词： Bismuth ferrite-barium titanate Acceptor doping Electroceramics piezoelectricity In-situ X-ray diffraction

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A deep convolutional neural network for diabetic retinopathy detection via mining local and long-range dependence

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CAAI Transactions on Intelligence Technology 2024年第1期9卷 153-166页

作者： Xiaoling Luo Wei Wang Yong Xu Zhihui Lai Xiaopeng Jin Bob Zhang david Zhang Shenzhen Key Laboratory of Visual Object Detection and Recognition Harbin Institute of TechnologyShenzhenChina peng Cheng Laboratory ShenzhenChina Shenzhen Institute of Artificial Intelligence and Robotics for Society ShenzhenChina College of Big Data and Internet Shenzhen Technology UniversityShenzhenChina The Department of Computer and Information Science University of MacaoMacaoMacaoChina The Chinese University of Hong Kong(Shenzhen) ShenzhenChina

Diabetic retinopathy(DR),the main cause of irreversible blindness,is one of the most common complications of *** present,deep convolutional neural networks have achieved promising performance in automatic DR detection *** convolution operation of methods is a local cross-correlation operation,whose receptive field de-termines the size of the local neighbourhood for ***,for retinal fundus photographs,there is not only the local information but also long-distance dependence between the lesion features(*** and exudates)scattered throughout the whole *** proposed method incorporates correlations between long-range patches into the deep learning framework to improve DR ***-wise re-lationships are used to enhance the local patch features since lesions of DR usually appear as *** Long-Range unit in the proposed network with a residual structure can be flexibly embedded into other trained *** experimental results demon-strate that the proposed approach can achieve higher accuracy than existing state-of-the-art models on Messidor and EyepACS datasets.

关键词： image classification medical image processing pattern recognition

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mRNA vaccines:a new era in vaccine development

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Oncology Research 2024年第10期32卷 1543-1564页

作者： SHUBHRA CHANDRA JENNIFER C.WILSON david GOOD MING Q.WEI School of pharmacy&Medical Sciences Gold Coast campusGriffith UniversityBrisbaneQLD-4222Australia Menzies Health Institute Queensland(MHIQ) Gold Coast CampusGriffith UniversityBrisbaneQLD-4215Australia School of Allied Health Australian Catholic UniversityBrisbaneQLD-4014Australia

The advent of RNA therapy,particularly through the development of mRNA cancer vaccines,has ushered in a new era in the field of *** article provides a concise overview of the key principles,recent advancements,and potential implications of mRNA cancer vaccines as a groundbreaking modality in cancer *** cancer vaccines represent a revolutionary approach to combatting cancer by leveraging the body’s innate immune *** vaccines are designed to deliver specific mRNA sequences encoding cancer-associated antigens,prompting the immune system to recognize and mount a targeted response against malignant *** personalized and adaptive nature of mRNA vaccines holds immense potential for addressing the heterogeneity of cancer and tailoring treatments to individual *** breakthroughs in the development of mRNA vaccines,exemplified by the success of COVID-19 vaccines,have accelerated their application in *** mRNA platform’s versatility allows for the rapid adaptation of vaccine candidates to various cancer types,presenting an agile and promising avenue for therapeutic *** trials of mRNA cancer vaccines have demonstrated encouraging results in terms of safety,immunogenicity,and *** candidates,such as BioNTech’s BNT111 and Moderna’s mRNA-4157,have exhibited promising outcomes in targeting melanoma and solid tumors,*** successes underscore the potential of mRNA vaccines to elicit robust and durable anti-cancer immune *** the field holds great promise,challenges such as manufacturing complexities and cost considerations need to be addressed for widespread *** development of scalable and cost-effective manufacturing processes,along with ongoing clinical research,will be pivotal in realizing the full potential of mRNA cancer ***,mRNA cancer vaccines represent a cutting-edge therapeutic approach that holds the promise of transforming cancer treatment.

关键词： Cancer immunotherapy Immune checkpoint preventive&therapeutic vaccine Delivery system mRNA

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Description of a novel robotic early post-prostatectomy anastomotic repair technique and institutional outcomes

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Asian Journal of Urology 2024年第3期11卷 366-372页

作者： david Strauss Eric Cho Matthew Loecher Matthew Lee Daniel Eun Department of Urology Lewis Katz School of MedicineTemple UniversityPhiladelphiaPAUSA

Objective:A vesicourethral anastomotic leak(VUAL)is a known complication following robotic-assisted radical *** natural history of a VUAL has been well described and is frequently managed with prolonged *** increasing emphasis on patient reported outcomes,catheter duration and VUAL are associated with significant short-term quality of life *** aimed to present a case series of our robotic early post-prostatectomy anastomotic repair technique,defined as revision within 6 weeks from index ***:A single institution prospective database identified eleven patients with a VUAL from July 2016 to October 2022 who underwent robotic early post-prostatectomy anastomotic repair by a single *** were diagnosed with a VUAL on pre-operative CT urogram or CT/fluoroscopic *** primary outcome was resolution of the anastomotic leak,defined as no contrast extravasation on post-operative *** outcomes included post-repair catheter duration and continence on the last follow-up defined as pad(s)per ***:The mean time to intervention after robotic-assisted radical prostatectomy was 21 *** of the eleven(72.7%)patients had no evidence of extravasation on postrepair *** range from intervention to first cystogram was 7e20 *** median catheter duration for those with successful intervention was 10 *** median catheter duration for those with the leak on initial post-operative cystogram was 20 *** a mean follow-up time of 25 months,eight(72.7%)patients reported using no pads per day,and three(27.3%)patients reported one pad per ***:Management of a VUAL has traditionally relied on prolonged catheter drainage and the tincture of *** the role of robotic reconstruction has been shown to be a viable modality for management of bladder neck contracture,it is important to reconsider prior dogmas of urologic *** case series suggests that an early repair is saf

关键词： Minimallyinvasive surgery Vesicourethral anastomotic leak Robotic-assisted laparoscopic reconstruction

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The first mitogenome of Lauraceae(Cinnamomum chekiangense)

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plant Diversity 2024年第1期46卷 144-148页

作者： Changwei Bi Ning Sun Fuchuan Han Kewang Xu Yong Yang david K.Ferguson State Key Laboratory of Tree Genetics and Breeding Co-Innovation Center for Sustainable Forestry in Southern ChinaKey Laboratory of Tree Genetics and Biotechnology of Educational Department of ChinaKey Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu ProvinceNanjing Forestry UniversityNanjing 210037China College of Information Science and Technology Nanjing Forestry UniversityNanjing 210037China Research Institute of Subtropical Forestry Chinese Academy of ForestryHangzhou 311400China Co-Innovation Center for Sustainable Forestry in Southern China College of Life SciencesNanjing Forestry UniversityNanjing 210037China Department of paleontology University of ViennaViennaAustria

There are three distinct genetic systems in higher plants,the dominant nuclear genome and the semi-autonomous organelle genomes(plastids and mitochondria).In contrast to the conserved plastid genome(plastome),the plant mitochondrial genome(mitogenome)is characterized by an intriguing“evolutionary paradox”distinguished by a remarkably low mutation rate but with a significantly high rearrangement rate(palmer and Herbon,1988;Lai et al.,2022).

关键词： autonomous distinguished palmer

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Failure mechanism and simulation for long run-out of the catastrophic rock landslide in the Shanyang Vanadium Mine,China

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Journal of Mountain Science 2024年第9期21卷 2905-2917页

作者： LIU Yinpeng Mumtaz HAIDER david-darnor LAWRENCE LI Tonglu SHEN Wei LI ping College of Geological Engineering and Geomatics Chang’an UniversityXi’an 710054China Observation and Research Station of Water Cycle and Geological Environment for the Chinese Loess plateau Ministry of EducationZhengning 745399China

On 12th August 2015,a massive rapid long run-out rock landslide occurred in the Shanyang Vanadium Mine in Shaanxi province,China,which claimed the lives of 65 *** heavy rainfalls,earthquakes,and mining blasts were recorded before the ***,the failure mechanism and the cause of the long run-out movement are always in *** this paper,we conducted a detailed field investigation,laboratory tests,block theory analysis,and numerical simulation to investigate the failure and long run-out mechanisms of the *** field investigation results show that the source material of the rock landslide is a huge dolomite wedge block bedding on siliceous shale *** compression tests indicate that the uniaxial compression strength of the intact dolomite is 130-140Mpa and the dolomite shows a brittle failure *** to the progressive downward erosion of the gully,the dolomite rock bridge at the slope toe became *** the compression stress in the dolomite bridge increased to surpass its strength,the brittle failure of the bridge *** huge potential energy was released following the disintegration of the landslide,which led to the high acceleration of this rock *** 3D discrete element simulation results suggest that the low intergranular friction contributes to the long run-out movement of this rock landslide.

关键词： Rock landslide Gully erosion Long run-out Wedge block Discrete element method

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Airway management of a patient with linear immunoglobulin A bullous dermatosis:A case report

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World Journal of Clinical Cases 2024年第13期12卷 2263-2268页

作者： Olga C Nin Robert Hutnik Neil N Chheda david Hutchinson Department of Anesthesiology University of Florida College of MedicineGainesvilleFL 32610United States Department of Otolaryngology University of Florida College of MedicineGainesvilleFL 32610United States

BACKGROUND There is limited literature on managing the airway of patients with linear immunoglobulin A(IgA)bullous dermatosis,a rare mucocutaneous disorder that leads to the development of friable *** clinical decision making is necessary when there is a risk of bleeding into the airway,and a multidisciplinary team approach may lead to decreased patient morbidity during these high-risk scenarios,especially when confronted with an unusual cause for *** SUMMARY A 45-year-old African American female presented to our ambulatory surgical center for right corneal transplantation due to corneal perforation after blunt trauma in the setting of cicatricial conjunctivitis and diffuse corneal neovascularization from linear IgA bullous *** diagnosis of IgA dermatosis was recent,and the patient had been lost to *** severity of the disease and extent of airway involvement was unknown at the time of the *** airway bleeding was noticed upon intubation and the otorhinolaryngology team had to be called to the operating *** patient required transfer to the intensive care unit where a multidisciplinary team was involved in her *** patient was extubated on postoperative day *** A multidisciplinary approach to treating this disease is the best course of action before a surgical *** our case,key communication between the surgery,anesthesia,and dermatology teams led to the quick and safe treatment of our patient’s *** surgery should not be considered for these cases unless they are in full remission and there is no mucous membrane involvement.

关键词： Airway management Bleeding risk Linear immunoglobulin A bullous dermatosis Multidisciplinary approach Outpatient procedure Case report

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流水车间加工信息测度与控制

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中国科学：技术科学 2024年第6期54卷 1091-1104页

作者：张志峰 JANET david 刘俊桂林航天工业学院管理学院桂林541004 Department of Engineering Science University of OxfordOxford OX13PJUK 华中科技大学机械科学与工程学院武汉430074

流水车间加工信息的有效测度是实施加工批量决策的前提.当前多品种小批量生产信息控制研究多以生产技术、范式及智能算法等理论优化工作为主,极少开展生产的加工批量与其状态控制所需信息之间关系的研究,导致研究结论过于理论化而难以... 详细信息

流水车间加工信息的有效测度是实施加工批量决策的前提.当前多品种小批量生产信息控制研究多以生产技术、范式及智能算法等理论优化工作为主,极少开展生产的加工批量与其状态控制所需信息之间关系的研究,导致研究结论过于理论化而难以应用于现实生产.针对此研究局限性,本文从信息论角度出发,根据制造马尔科夫过程,定义流水车间的加工批量信息熵并解析其度量特性.进一步,构建流水车间加工批量信息熵函数,理论上证明其函数单调递减性.通过建立流水车间加工批次信息测度模型,确定生产线批次加工信息的组成结构,实现对工件加工所需信息量的测度.实证研究中,将平均调整准备时间、平均加工时间及完工时间等观测数据应用于实际企业的减速器生产线,做出不同参量与加工批量变化关系图,确定相关参数条件下生产线的最优加工批量.根据研究结果,提出有效减少管理与控制生产线所需信息量的对策,在验证所建熵模型科学性与有效性的同时,也为实际生产中的批量决策提供准确的现实指导.

关键词：流水车间加工批量熵函数信息测度

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Multi‑omics integration identifies regulatory factors underlying bovine subclinical mastitis

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Journal of Animal Science and Biotechnology 2024年第3期15卷 987-1007页

作者： Mengqi Wang Naisu Yang Mario Laterriere david Gagne Faith Omonijo Eveline M.Ibeagha‑Awemu Agriculture and Agri‑Food Canada Sherbrooke Research and Development CentreSherbrookeQCCanada Department of Animal Science Universite LavalQuebec CityQCCanada Quebec Research and Development Centre Agriculture and Agri-Food CanadaQuebec CityQCCanada

Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy ***-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease ***,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus *** Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical *** abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),***,5 factors presenting the principal variation of differential multi-omics signatures were *** important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were *** of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical ***,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regu

关键词： Candidate discriminant multi-omics signature Gene Long non-coding RNA Methylation haplotype block MicroRNA Multi-omics integration Natural killer cell mediated cytotoxicity pathway Staphylococcus aureus infection pathway

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