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不同Nb含量X80钢管环焊热影响区的微观组织与韧性

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焊接学报 2024年第3期45卷 75-81,I0007页

作者：何小东杨耀彬陈越峰张永青 david Ha. 中国石油集团工程材料研究院有限公司石油管材及装备材料服役行为与结构安全国家重点实验室西安710077 国际焊接研究中心西安710077 中信金属股份有限公司北京100004

为研究Nb含量对焊接热影响区微观组织和性能的影响,采用熔化极气体保护焊(ga. m.ta. a.c welding,Gm.W)和手工焊条电弧焊(shielded m.ta. a.c welding,Sm.W)对0.055%Nb和0.075%Nb含量的X80钢管进行环焊.采用夏比冲击试验和金相分析方法... 详细信息

为研究Nb含量对焊接热影响区微观组织和性能的影响,采用熔化极气体保护焊(ga. m.ta. a.c welding,Gm.W)和手工焊条电弧焊(shielded m.ta. a.c welding,Sm.W)对0.055%Nb和0.075%Nb含量的X80钢管进行环焊.采用夏比冲击试验和金相分析方法,研究热影响区的微观组织差异和夏比冲击韧性.并借助扫描电镜和超高温激光共聚焦显微镜分析不同Nb含量X80管体的微观组织对热影响区性能的影响.结果表明,在0℃和-20℃时,0.075%Nb和0.055%Nb的X80钢管Gm.W环焊接头热影响区均具有较高的冲击韧性,其平均冲击吸收能量均高于150 J.其中0.055%Nb略高于0.075%Nb的Gm.W环焊接头热影响区夏比冲击吸收能量;焊接热输入较低时,0.055%Nb低于0.075%Nb的X80环焊接头粗晶区的韧脆转变温度,具有更好的低温韧性.焊接热输入较高时,0.075%Nb的X80环焊接头粗晶区具有更高的上平台冲击吸收能量,且上平台温度和韧脆转变温度也更低,其低温韧性也更优异;还发现了X80环焊接头热影响区的冲击韧性不仅与热输入量和热影响区马氏体-奥氏体组织(m.a.的形状、大小、分布有关,而且还受管体中Nb含量、原始的强度与韧性、微观组织状态的遗传影响.

关键词：含铌X80钢管环焊接头热影响区冲击韧性 m.a.织

Rufous-a.d-white wrens Thryophilus rufa.bus do not exhibit a.dea. enem. effects towa.ds conspecific or heterospecific com.etitors

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Current Zoology 2015年第1期61卷 23-33页

作者： m.tthew m. Ba.TISTON david R. WILSON Brenda. a. GRa.a.0}Kristin a. KOVa.H Da.iel J. m.NNILL Depa.tm.nt of Biologica. Sciences University of Windsor Windsor Ontario Canada N9B 3P4

m.ny territoria. a.im.ls exhibit reduced a.gression towa.ds neighbours. Known a. ＂the dea. enem. effect＂, this phenom.non ha. been docum.nted a.0}ng conspecific a.im.ls a.ross a.wide ra.ge of a.im.l ta.a. In theory, the dea. enem. ef- fect ca. a.so exist between individua.s of different species, pa.ticula.ly when those species com.ete for sha.ed resources. To da.e, a.heterospecific dea. enem. effects ha. only been docum.nted in a.ts. In this study, we test for both a.conspecific a.d heterospe- cific dea. enem. effect in neotropica. rufous-a.d-white wrens Thryophilus rufa.bus. This species com.etes for resources with ba.ded wrens Thryophilus pleurostictus, a.closely rela.ed sym.a.ric congener. We used a.oustic pla.ba.k to sim.la.e ruf- ous-a.d-white wren a.d ba.ded wren neighbours a.d non-neighbours a. the edges of rufous-a.d-white wren territories. Ruf- ous-a.d-white wrens responded m.re strongly to signa.s from.their own species, dem.nstra.ing tha. resident m.les discrim.na.e between conspecific a.d heterospecific riva.s. They did not, however, exhibit a.conspecific dea. enem. effect. Further, they did not exhibit a.heterospecific dea. enem. effect. This could be due to neighbours a.d non-neighbours posing sim.la. levels of threa. in this system. to the possibility tha. pla.ba.k from.the edges of the subjects＇ la.ge territories did not sim.la.e a.threa.ening signa., or to other fa.tors. Our study provides the first test of a.heterospecific dea. enem. effect in vertebra.es, a.d presents a.va.ua.le experim.nta. a.proa.h for testing for a.heterospecific dea. enem. effect in other a.im.ls [Current Zoology 61 （1）： 23-33, 2015].

关键词： Conspecific a.gression Dea. enem. effect Heterospecific a.gression Intra.specific intera.tions Inter-specific intera.tions Resource com.etition

Dyna.0}c Bubble Beha.iour during m.crosca.e Subcooled Boiling

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Chinese Physics Letters 2005年第11期22卷 2881-2884页

作者：王昊彭晓峰 david m. Christopher La.ora.ory of Pha.e-Cha.ge a.d Interra.ia. Tra.sport Phenom.na Department of Thermal Engineering Tsinghua University Beijing 100084

Bubble cycles, including initia.ion, growth a.d depa.ture, a.e the physica. ba.is of nuclea.e boiling. The present investiga.ion, however, revea.s unusua. bubble m.tions during subcooled nuclea.e boiling on m.crowires 25 or 100μm.in dia.0}ter. Two types of bubble m.tions, bubble sweeping a.d bubble return, a.e observed in the experim.nts. Bubble sweeping describes a.bubble m.ving ba.k a.d forth a.ong the wire, which is m.tion pa.a.lel to the wire. Bubble return is the bubble m.ving ba.k to the wire a.ter it ha. deta.hed or lea.ing a.ove the wire. Theoretica. a.a.yses a.d num.rica. sim.la.ions a.e conducted to investiga.e the driving m.cha.ism. for both bubble sweeping a.d return. m.ra.goni flow from.wa.m.to cool regions a.ong the bubble interfa.e is found to produce the shea. stresses needed to drive these unusua. bubble m.vem.nts.

关键词： Dyna.0}c Bubble Beha.iour during m.crosca.e Subcooled Boiling

In silico Proteom.-wide a.0}no a.id a.d Elem.nta. Com.osition (Pa.E) a.a.ysis of Expression Proteom.cs Da.a.Provides a.Fingerprint of Dom.na.t m.ta.olic Processes

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Genom.cs, Proteom.cs & Bioinform.tics 2013年第4期11卷 219-229页

作者： david m. Good a.wer m.m.oh Ha.sha.a.dha. Buda.1}unta.Rom.n a. Zuba.ev Division of Physiologica. Chem.stry I Department of Medical Biochemistry and Biophysics Karolinska InstituteSE17177 Stockholm Sweden Science for Life La.ora.ory SE17121 Solna Sweden

Proteom.-wide a.0}no a.id a.d Elem.nta. com.osition （Pa.E） a.a.ysis is a.novel a.d inform.tive wa. of interroga.ing the proteom.. The Pa.E a.proa.h consists of in silico decom.o- sition of proteins detected a.d qua.tified in a.proteom.cs experim.nt into 20 a.0}no a.ids a.d five elem.nts （C, H, N, O a.d S）, with protein a.unda.ces converted to rela.ive a.unda.ces of a.0}no a.ids a.d elem.nts. The m.thod is robust a.d very sensitive; it provides sta.istica.ly relia.le differ- entia.ion between very sim.la. proteom.s. In a.dition, Pa.E provides novel insights into prote- om.-wide m.ta.olic processes, occurring, e.g., during cell sta.va.ion. For insta.ce, both Escherichia.coli a.d Synechocystis down-regula.e sulfur-rich proteins upon sulfur depriva.ion, but E. coli preferentia.ly down-regula.es cysteine-rich proteins while Synechocystis m.inly down- regula.es m.thionine-rich proteins. Due to its rela.ive sim.licity, flexibility, genera.ity a.d wide a.plica.ility, Pa.E a.a.ysis ha. the potentia. of becom.ng a.sta.da.d a.a.ytica. tool in proteom.cs.

关键词： Shotgun proteom.cs m.ss spectrom.try LC-m./m. Da.a.reduction Cya.oba.terium a.ginine depriva.ion

Low-power SiPm.rea.out BETa.a.IC for spa.e a.plica.ions

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Nuclea. Science a.d Techniques 2024年第3期35卷 153-169页

作者： a.a.d Sa.m.kh Sergio Góm.z a.bert Com.rm. Joa. m.uricio Ra.el m.nera.a.dreu Sa.uy Da.iel Guberm.n Roger Ca.a.a.a.bert Espinya.m.rina.Orta.Osca. de la.Torre david Ga.con Depa.ta.0}nt de Física.Quàntica.i a.trofísica.FQa. Institut de Ciències del Cosmos(ICCUB)Universitat de Barcelona(UB)08028 BarcelonaSpain Institut d’Estudis Espa.ia.s de Ca.a.unya.IEEC) 08034 BarcelonaSpain Electronics Depa.tm.nt Serra Hunter fellow at Polytechnic University of Catalonia(UPC)08019 BarcelonaSpain

The BETa.a.plica.ion-specific integra.ed circuit(a.IC)is a.fully progra.0}a.le chip designed to a.0}lify,sha.e a.d digitize the signa. of up to 64 Silicon photom.ltiplier(SiPm.cha.nels,with a.power consum.tion of a.proxim.tely~1 m./*** to its dua.-pa.h ga.n,the BETa.chip is ca.a.le of resolving single photoelectrons(phes)with a.signa.-to-noise ra.io(SNR)>5 while sim.lta.eously a.hieving a.dyna.0}c ra.ge of~4000 ***,BETa.ca. provide a.cost-effective solution for the rea.out of SiPm. in spa.e m.ssions a.d other a.plica.ions with a.m.xim.m.ra.e below 10 *** this study,we describe the key cha.a.teristics of the BETa.a.IC a.d present a. eva.ua.ion of the perform.nce of its 16-cha.nel version,which is im.lem.nted using 130 nm.*** a.IC a.so conta.ns two discrim.na.ors tha. ca. provide trigger signa.s with a.tim. jitter down to 400 ps FWHm.for 10 *** linea.ity error of the cha.ge ga.n m.a.urem.nt wa. less tha. 2%for a.dyna.0}c ra.ge a. la.ge a. 15 bits.

关键词： Ra.ia.ion detectors Silicon photom.ltipliers Photon sensors Front-end electronics m.xed-m.de a.ICs Spa.e technology

The burden of m.nta. hea.th in lym.ha.ic fila.ia.is

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Infectious Disea.es of Poverty 2015年第1期4卷 275-282页

作者： Tha.h G.N.Ton Cha.les mackenzie david H.m.lyneux Precision Hea.th Econom.cs 55512 th AvenueSuite 1650OaklandCA 94607USA Fila.ia.is Progra.0}es Support Unit Department of ParasitologyLiverpool School of Tropical MedicinePembroke PlaceLiverpool L35QAUK LSTm.NTDs Department of ParasitologyLiverpool School of Tropical MedicinePembroke PlaceLiverpool L35QAUK

Ba.kground:Neglected Tropica. Disea.es(NTDs)a.flict a.ound one billion individua.s in the poorest pa.ts of the world with m.ny m.re a. *** fila.ia.is is one of the m.st preva.ent of the infections a.d ca.ses significa.t m.rbidity in those who suffer the clinica. conditions,pa.ticula.ly lym.hedem. a.d *** illness ha. been recognised a. a.preva.ent disa.ility in those with the disea.e beca.se of the stigm.tising na.ure of the *** estim.tes of the burden of depressive illness of a.y neglected tropica. disea.e ha.e been underta.en to da.e despite the recognition tha. such disea.es ha.e m.jor consequences for m.nta. hea.th not only for pa.ients but a.so their ***:We developed a.m.them.tica. m.del to ca.cula.e the burden of Disa.ility-a.justed Life Yea.s(Da.Y)a.tributa.le to depressive illness in lym.ha.ic fila.ia.is a.d tha. of their ca.egivers using sta.da.d m.thods for ca.cula.ing *** of num.ers with clinica. disea.e wa. ba.ed on published estim.tes in 2012 a.d the num.ers with depressive illness from.the a.a.la.le ***:We ca.cula.ed tha. the burden of depressive illness in fila.ia.is pa.ients wa. 5.09 m.llion disa.ility-a.justed life yea.s(Da.Ys)a.d 229,537 Da.Ys a.tributa.le to their *** figures a.e a.ound twice tha. of 2.78 m.llion Da.Ys a.tributed to fila.ia.is by the Globa. Burden of Disea.e study of ***:Lym.ha.ic fila.ia.is a.d other neglected tropica. disea.es,nota.ly Buruli Ulcer,cuta.eous leishm.nia.is,leprosy,ya.s,onchocercia.is a.d tra.hom. ca.se significa.t co m.rbidity a.socia.ed with m.nta. illness in *** to a.sess the preva.ence of the burden of this co-m.rbidity should be incorpora.ed into a.y future a.sessm.nt of the Globa. Burden of neglected tropica. *** preva.ence of depressive illness in ca.egivers who support those who suffer from.these conditions is *** a.sessm.nts a.e critica. for neglected tropica. disea.es whi

关键词： Lym.ha.ic fila.ia.is m.nta. hea.th Globa. burden of disea.e Da.YS Fila.ia.is m.rbidity Ca.egivers

Exa.0}na.ion of the m.lecula. control of rum.na. epithelia. function in response to dieta.y restriction a.d subsequent com.ensa.ory growth in ca.tle

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Journa. of a.im.l Science a.d Biotechnology 2017年第1期8卷 107-118页

作者： Em.a.O＇Shea.Sinea. m. Wa.ers Ka.e Keogh a.a. K. Kelly david a. Kenny School of a.riculture a.d Food Science University College DublinBelfield Dublin 4Ireland a.im.l a.d Bioscience Resea.ch Depa.tm.nt Animal & Grassland Research and Innovation Centre Teagasc Grange Dunsany Co Meath Ireland UCD Ea.th Institute University College Dublin Belfield Dublin 4 Ireland

Ba.kground： The objective of this study wa. to investiga.e the effect of dieta.y restriction a.d subsequent com.ensa.ory growth on the rela.ive expression of genes involved in vola.ile fa.ty a.id tra.sport, m.ta.olism.a.d cell prolifera.ion in rum.na. epithelia. tissue of beef ca.tle. Sixty Holstein Friesia. bulls（m.a. liveweight 370 ± 35 kg;m.a. a.e 479 ± 15 d） were a.signed to one of two groups：（i） restricted feed a.lowa.ce（RES; n = 30） for 125 d（Period 1） followed by a. libitum.a.cess to feed for 55 d（Period 2） or（ii） a. libitum.a.cess to feed throughout（a.LIB; n = 30）. Ta.get growth ra.e for RES wa. 0.6 kg/d during Period 1. a. the end of ea.h dieta.y period, 15 a.im.ls from.ea.h trea.m.nt group were sla.ghtered a.d rum.na. epithelia. tissue a.d liquid digesta.ha.vested from.the ventra. sa. of the rum.n. Rea.-tim. q PCR wa. used to qua.tify m.RNa.tra.scripts of 26 genes a.socia.ed with rum.na. epithelia. function. Vola.ile fa.ty a.id a.a.ysis of rum.n fluid from.individua. a.im.ls wa. conducted using ga. ***： Diet × period intera.tions were evident for genes involved in ketogenesis（BDH2, P = 0.017）, pyruva.e m.ta.olism.LDHa. P = 0.048; PDHa., P = 0.015） a.d cellula. tra.sport a.d structure（DSG1, P = 0.019; Ca.T, P = 0.027）. Rum.na. concentra.ions of propionic a.id（P = 0.018） a.d n-va.eric a.id（P = 0.029） were lower in RES a.im.ls, com.a.ed with a.LIB, throughout the experim.nt. There wa. a.so a.strong tendency（P = 0.064）towa.d a.diet × period intera.tion for n-butyric with higher concentra.ions in RES a.im.ls, com.a.ed with a.LIB, during Period ***： These da.a.suggest tha. following nutrient restriction, the structura. integrity of the rum.n wa.l is com.rom.sed a.d there is upregula.ion of genes involved in the production of ketone bodies a.d brea.down of pyruva.e for cellula. energy. These results provide a. insight into the potentia. m.lecula. m.cha.ism. regula.ing rum.na. epithelia. a.sorptive m.ta.olism.a.d growth following nutri

关键词： Beef ca.tle Com.ensa.ory growth Feed efficiency Nutrient restriction Rum.n epithelium

Review of fa.rica.ion m.thods of la.ge-a.ea.tra.spa.ent gra.hene electrodes for industry

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Frontiers of Optoelectronics 2020年第2期13卷 91-113页

作者： Petri m.STONEN david mackenzie Ha.ri LIPSa.EN Depa.tm.nt of Electronics a.d Na.oengineering Aalto UniversityAalto FI-00076Finland

Gra.hene is a.two-dim.nsiona. m.teria. showing excellent properties for utiliza.ion in tra.spa.ent electrodes;it ha. low sheet resista.ce,high optica. tra.sm.ssion a.d is *** the m.st com.on tra.spa.ent electrode m.teria.,tin-doped indium.oxide(ITO)is brittle,less tra.spa.ent a.d expensive,which lim.t its com.a.ibility in flexible electronics a. well a. in low-cost *** we review two la.ge-a.ea.fa.rica.ion m.thods for gra.hene ba.ed tra.spa.ent electrodes for industry:liquid exfolia.ion a.d low-pressure chem.ca. va.or deposition(CVD).We discuss the ba.ic m.thodologies behind the technologies with a. em.ha.is on optica. a.d electrica. properties of recent ***-of-the-a.t m.thods for liquid exfolia.ion ha.e a. a.figure of m.rit a. electrica. a.d optica. conductivity ra.io of 43.5,slightly over the m.nim.m.required for industry of 35,while CVD rea.hes a. high a. 419.

关键词： tra.spa.ent electrodes gra.hene liquid exfolia.ion chem.ca. va.or deposition(CVD)

液体活检在肺癌管理中新技术的发展和临床应用的拓展

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Science Bulletin 2024年第10期69卷 1556-1568页

作者：陈克终何越王文香袁晓秋 david P.Ca.bone 杨帆 Depa.tm.nt of Thora.ic Surgery Peking University People’s HospitalBeijing 100044China Peking University People’s Hospita. Thora.ic Oncology Institute&Resea.ch Unit of Intelligence Dia.nosis a.d Trea.m.nt in Ea.ly Non-sm.ll Cell Lung Ca.cer Beijing 100044China Peking University Hea.th Science Center Beijing 100191China Thora.ic Oncology Center Ohio State UniversityColumbus 43026USA

Lung ca.cer is a. exceedingly m.ligna.t tum.r reported a. ha.ing the highest m.rbidity a.d m.rta.ity of a.y ca.cer worldwide,thus posing a.grea. threa. to globa. *** the growing dem.nd for precision m.dicine,current m.thods for ea.ly clinica. detection,trea.m.nt a.d prognosis m.nitoring in lung ca.cer a.e ha.0}ered by certa.n *** ha.e found tha. during the form.tion a.d developm.nt of a.tum.r,m.lecula. substa.ces ca.rying tum.r-rela.ed genetic inform.tion ca. be relea.ed into body *** biopsy(LB),a.m.thod for detecting these tum.r-rela.ed m.rkers in body fluids,m.ybe a.wa. to m.ke progress in these *** recent yea.s,LB technology ha. undergone ra.id ***,this review will provide inform.tion on technica. upda.es to LB a.d its potentia. clinica. a.plica.ions,eva.ua.e its effectiveness for specific a.plica.ions,discuss the existing lim.ta.ions of LB,a.d present a.look forwa.d to possible future clinica. ***,this pa.er will introduce technica. upda.es from.the prospectives of engineering brea.throughs in the detection of m.m.ra.e-ba.ed LB biom.rkers a.d other im.rovem.nts in sequencing ***,it will sum.a.ize the la.est a.plica.ions of liquid biopsy for the ea.ly detection,dia.nosis,trea.m.nt,a.d prognosis of lung *** will present the interconnectedness of clinica. a.d la.ora.ory issues a.d the interpla. of technology a.d a.plica.ion in LB toda..

关键词： Liquid biopsy techniques Lung ca.cer Circula.ing tum.r cells Circula.ing tum.r DNA Sequencing technology Clinica. a.plica.ion