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毛滴虫病

国际内科双语杂志（中英文） 2006年第5期6卷 19-20,53-54页

作者： david A lewis 陈金波（译）渠涛（校）南非约翰内斯堡国立传染病性传播感染参比中心的负责人不详

毛滴虫病是一种常见的性传播感染（STI），由毛滴虫感染引起。阴道毛滴虫是一种有5根鞭毛的原虫，其鞭毛与这种生物的特征性运动有关。生长环境较差时这些鞭毛可以内收消失，形成的这种假孢囊是否有活力及能否转化成其鞭毛形式还不清楚。

关键词：毛滴虫病毛滴虫感染阴道毛滴虫生长环境鞭毛特征性

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社会发展的大众文化表现(节译)

新闻研究导刊 2018年第9期9卷 147-147,159页

作者：付蓉 david lewis Dennis Rodgers Michael Woolcock 新华社信息中心重庆中心重庆401121

较之主流的经济发展量化研究和实验性研究方式,通俗文化(小说、电影、电视和社交媒体)能为发展进程提供更加广阔或更富于洞见和人文形式的表现方式。通俗文化和传统社会科学的对话将彼此受益;而在反事实推理、展现现代性后果方面,通俗... 详细信息

较之主流的经济发展量化研究和实验性研究方式,通俗文化(小说、电影、电视和社交媒体)能为发展进程提供更加广阔或更富于洞见和人文形式的表现方式。通俗文化和传统社会科学的对话将彼此受益;而在反事实推理、展现现代性后果方面,通俗文化则更能表现出发展进程的复杂性、争议性和多元性。

关键词：社会发展大众文化表现媒体

Identification and treatment of individuals with attentiondeficit/ hyperactivity disorder and substance use disorder: An expert consensus statement

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World Journal of Psychiatry 2023年第3期13卷 84-112页

作者： Susan Young Cyrus Abbasian Zainab Al-Attar Polly Branney Bill Colley Samuele Cortese Sally Cubbin Quinton Deeley Gisli Hannes Gudjonsson Peter Hill Jack Hollingdale Steve Jenden Joe Johnson Deborah Judge Alexandra lewis Peter Mason Raja Mukherjee david Nutt Jane Roberts Fiona Robinson Emma Woodhouse Kelly Cocallis Department of Psychology Psychology Services LimitedCroydon CR97AEUnited Kingdom Department of Psychology Reykjavik UniversityReykjavikIceland Psychiatry-UK Limited Cornwall PL339ETUnited Kingdom ADHD and Autism Oxford ADHD&Autism CentreHeadington OX37BXUnited Kingdom CLC Consultancy Dunkeld PH80AYUnited Kingdom Center for Innovation in Mental Health School of PsychologyFaculty of Environmental and Life SciencesUniversity of SouthamptonSouthampton SO171BJUnited Kingdom Adult ADHD Adult ADHD Clinic LtdOxford OX37RPUnited Kingdom Forensic and Neurodevelopmental Science Institute of PsychiatryPsychology&NeuroscienceKing's College London Institute of PsychiatryLondon SE58AFUnited Kingdom Department of Psychology Institute of PsychiatryPsychology&NeuroscienceKing's College LondonLondon SE58AFUnited Kingdom Department of Psychiatry University of LondonLondon WC1E 7HUUnited Kingdom Department of Psychology Compass Psychology Services LtdLondon BR19DXUnited Kingdom Birribi Ltd Narberth SA677DUUnited Kingdom Halton and Knowsley Adult ADHD Team Merseycare NHS Foundation TrustWinwick WA29WAUnited Kingdom Department of Psychiatry Fulbourn HospitalCambridge CB215EFUnited Kingdom Department of Psychiatry Dr Peter Mason ADHD&Psychiatry Services LimitedLiverpool L19ARUnited Kingdom Adult Neurodevelopmental Service Horizon HouseEpsom KT174QJUnited Kingdom Department of Psychiatry Imperial College LondonLondon WS120NNUnited Kingdom Service User Representative Gloucestershire GL13NNUnited Kingdom Drug&Alcohol Services Surrey&Borders Partnership TrustLeatherhead KT227ADUnited Kingdom Forensic and Neurodevelopmental Sciences Institute of PsychiatryPsychology&NeuroscienceKing's College LondonLondon SE58AFUnited Kingdom Wansbeck General Hospital Northumbria Healthcare NHS Foundation TrustAshington NE639JJUnited Kingdom

Attention-deficit/hyperactivity disorder(ADHD)often co-occurs with substance use(SU)and/or substance use disorder(SUD).Individuals with concurrent ADHD and SU/SUD can have complex presentations that may complicate diagnosis and *** can be further complicated by the context in which services are ***,when working with young people and adults with co-existing ADHD and SU/SUD,there is uncertainty among healthcare practitioners on how best to meet their *** February 2022,the United Kingdom ADHD Partnership hosted a meeting attended by multidisciplinary experts to address these *** presentations providing attendees with an overview of the literature,group discussions were held synthesizing research evidence and clinical *** included:(1)A review of substances and reasons for use/misuse;(2)identification,assessment and treatment of illicit SU/SUD in young people and adults with ADHD presenting in community services;and(3)identification,assessment and treatment of ADHD in adults presenting in SU/SUD community and inpatient *** highlighted inter-service barriers and fragmentation of *** was concluded that a multimodal and multi-agency approach is *** consensus group generated a table of practice recommendations providing guidance on:identification and assessment;pharmacological and psychological treatment;and multi-agency interventions.

关键词： Attention-deficit/hyperactivity disorder Substance use Pharmacokinetics Assessment Treatment Comorbidity

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射程族技术在空战分析中的应用

航空火控译丛 1979年第4期 25-40页

作者： Michael D.cilelti lewis Meier david M.Salmon 夏系统控制公司系统效率部系统控制公司系统效率部研究工程师加利福尼亚paloAlto) 主管工程师加利福尼亚paloAlto) 经理加利福尼亚paloAlto)

本文将用射程组技术的方法陈述从了解可能的飞机和武器性能鉴定空战双方的问题。这技术首先确定从一初始飞机状态能到达的那个位置族,其次确定从一初始状态武器能被投到的位置族。第一种曲红族描述了飞机的性能,第二种族描述飞机和武器... 详细信息

本文将用射程组技术的方法陈述从了解可能的飞机和武器性能鉴定空战双方的问题。这技术首先确定从一初始飞机状态能到达的那个位置族,其次确定从一初始状态武器能被投到的位置族。第一种曲红族描述了飞机的性能,第二种族描述飞机和武器系统的综合性能。飞极及飞机/武器的到达位置族被综合成每个战斗者的捕获区。

关键词：捕获区从一立义性能鉴定初始状态文叙伟曲主用假足他色

Experimental Intramammary Infection with a Strain of <i>Escherichia coli</i>Isolated from a Cow with Persistent <i>E. coli</i>Mastitis

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Open Journal of Veterinary Medicine 2012年第4期2卷 186-190页

作者： Stephen P. Oliver Susan I. Headrick Mark J. lewis Barbara E. Gillespie david L. Johnson Raul A. Almeida Department of Animal Science The University of Tennessee Knoxville USA East Tennessee Research and Education Center Little River Animal and Environmental Unit The University of Tennessee Knoxville USA Middle Tennessee Research & Education Center The University of Tennessee Spring Hill USA

Transient E. coli intramammary infections (IMI) are usually associated with rapid onset of clinical signs including mammary gland swelling and abnormal milk with rapid clearance of bacteria from milk. Conversely, reports have described strains of E. coli showing very different clinical trends. Persistent E. coli IMI are associated with mild clinical symptoms that disappear shortly after the onset of infection, possibly flaring-up intermittently during lactation. In the present study, we evaluated a strain of E. coli isolated from a cow with persistent mastitis to determine if the experimental infection model mimics naturally occurring persistent E. coli IMI. Uninfected mammary quarters of 7 Holstein heifers were infused within 10 days of calving with 50 colony-forming units of a persistent E. coli strain. Six of 7 heifers developed mild clinical mastitis with elevated rectal temperatures within 9 to 36 h after infusion. The challenge strain was isolated intermittently in milk from all infected mammary quarters during the first two weeks after infusion and 3 animals continued to shed E. coli periodically during the sampling period. One animal shed E. coli intermittently in milk for 172 d after challenge and developed clinical mastitis four times during this period. The isolated strain had an identical pulsed-field gel electrophoresis profile as the E. coli strain used to infuse mammary glands. The experimental IMI model described here mimics very closely naturally occurring persistent E. coli IMI, thus providing an excellent in vivo model to better understand pathogenesis and to facilitate development of control strategies for this important mastitis pathogen.

关键词： Escherichia coli Intramammary Experimental Infection Persistent Mastitis Dairy Cows

Soil fungal and prokaryotic community structure exhibits differential short-term responses to timber harvest in the Pacific Northwest

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Pedosphere 2020年第1期30卷 109-125页

作者： Rachel E.DANIELSON Megan L.MCGINNIS Scott M.HOLUB david D.MYROLD Department of Crop and Soil Science Oregon State UniversityCorvallis OR 97331-7306(USA) United State Forest Service Helena-Lewis and Clark National Forest2880 Skyway DriveHelena MT 59602(USA) Weyerhaeuser Company PO Box 275Springfield OR 97477(USA) Department of Land Airand Water ResourcesUniversity of CaliforniaDavis CA 95616USA

Conventional clear-cut timber harvest is a widespread industrial practice across the Pacific Northwest;however,information regarding how these practices impact soil microbial community structure at the regional scale is *** evidence of consistent and substantial impact of harvest on soil microbial functional profiles across the region(despite a range of environmental conditions),the objective of this study was to determine the extent to which harvest also influences the structure of prokaryotic and fungal soil microbial communities,and how generalized these trends are throughout the geographic *** soil samples were collected one year before and after harvest across nine second-growth Douglas-fir forests in the Pacific *** community DNA was extracted from the soils,and high-throughput targeted gene sequencing of the 16 S r RNA gene for prokaryotes and the internal transcribed spacer(ITS)gene for fungi was *** diversity was consistently and significantly higher after harvest;it was moderately so for fungal communities(+14.6%),but only marginally so for prokaryotic communities(+2.0%).Similarly,on average,a greater proportion of the variation in the community structure of fungi(20.1%)at each site was associated with forest harvest compared to that of prokaryotes(13.2%).Overall,the greatest influence of timber harvest on soil microbial communities appeared to be a relative depletion of ectomycorrhizal fungi,with a concomitant enrichment of saprotrophic *** the short-term responses of soil microbial communities across the region,particularly those of tree root-associated symbionts,may aid our understanding of the role soil microbial communities play in ecological succession.

关键词： clear-cut Douglas-fir forest ectomycorrhizal fungi forest soil microbial community microbial diversity root-associated symbiont saprotrophic fungi

在人类表型本体论中对癫痫发作进行建模——根据当代ILAE概念使大的表型数据易于处理

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癫痫杂志 2022年第5期8卷 457-468页

作者： david lewis-Smith Peter D Galer Ganna Balagura 黄格格(译) 牛永利(译) 杨建仲(审) 不详

癫痫的临床特征决定了如何定义癫痫,进而指导治疗。因此,在对癫痫病因、轨迹和治疗反应的研究中,考虑构成癫痫的基本临床实体至关重要。人类表型本体论(Human phenotype ontology,HPO)广泛应用于临床和遗传学研究中用于临床特征的简明... 详细信息

癫痫的临床特征决定了如何定义癫痫,进而指导治疗。因此,在对癫痫病因、轨迹和治疗反应的研究中,考虑构成癫痫的基本临床实体至关重要。人类表型本体论(Human phenotype ontology,HPO)广泛应用于临床和遗传学研究中用于临床特征的简明交流和建模,其允许使用逻辑推理来协调提取的数据。我们试图重新设计HPO癫痫亚本体,以提高其与当前癫痫概念的一致性,同时支持在高通量临床和基因组研究中应用大型临床数据集。根据2017年国际抗癫痫联盟对癫痫发作类型的分类,我们创建了一个新的HPO癫痫亚本体,并在不同细节层次上整合了癫痫持续状态、热性惊厥、反射性发作和新生儿癫痫的概念。我们比较了修订前后的HPO癫痫亚本体,根据3个独立队列中791例患者的癫痫发作信息可以推断:其中2个独立队列的信息先前已发表过,还有150例患者是新招募的。每个队列的数据以不同的格式提供,并通过两个版本的HPO进行协调。新的癫痫亚本体将癫痫发作的描述性概念数量增加了5倍。可标注到队列中的癫痫发作描述符号数量增加了40%,关于个体癫痫发作的信息总量增加了38%。最重要的定性差异是局灶性进展为双侧强直-阵挛发作与全面起始和局灶起始发作的关系。我们已经生成了一个详细的当代概念图,用于协调临床癫痫发作数据,并在2020-12-07 HPO的官方版本中实施,并在***免费提供。这将有助于克服基因组学中的表型瓶颈,促进有价值数据的再利用,并最终提高对癫痫的诊断和精准治疗。

关键词：大数据分类癫痫遗传学

Taking care of volunteers in a stroke trial: a new assisted-management strategy

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Stroke & Vascular Neurology 2016年第3期1卷 108-114页

作者： Amber C Stuart Jason J Sico Catherine M Viscoli Ashis H Tayal Silvio E Inzucchi Gary A Ford Karen L Furie Robert Cote J david Spence david Tanne Walter N Kernan on behalf of the IRIS Trial Investigators Department of Internal Medicine Yale University School of MedicineNew HavenConnecticutUSA Department of Neurology Yale University School of MedicineNew HavenConnecticutUSA Department of Neurology Service Veterans Affairs Connecticut Healthcare SystemWest HavenConnecticutUSA Neuroscience Institute Allegheny Health NetworkPittsburghPennsylvaniaUSA lewis Katz School of Medicine at Temple University PhiladelphiaPennsylvaniaUSA Division of Medical Sciences Oxford UniversityOxfordUK The Warren Alpert Medical School of Brown University ProvidenceRhode IslandUSA Department of Neurology Neurosurgery and MedicineMcGill UniversityMontrealQuebecCanada University of Western Ontario LondonOntarioCanada 10Sheba Medical CenterTel Aviv UniversityTel AvivIsrael 不详

Background and purpose:Providing participants with evidence-based care for secondary prevention is an ethical and scientific priority for trials in stroke *** optimal strategy,however,is *** report the performance of a new approach for delivering preventive care to trial ***:Participants were enrolled in the Insulin Resistance Intervention after Stroke trial,which examined the insulin sensitiser,pioglitazone versus placebo for prevention of stroke and myocardial infarction after ischaemic stroke or transient ischaemic *** care was the responsibility of the participants’personal healthcare providers,but investigators monitored care and provided feedback *** studied achievement of 8 prevention goals at baseline and 3 annual visits,with a focus on 3 priority goals:blood pressure<140/90 mm Hg,lowdensity lipoprotein(LDL)cholesterol<2.59 mmol/L and antithrombotic ***:The proportion of participants achieving the priority goals was highest for antithrombotic use(96–99%in each year)and similar for blood pressure(66–72%in each year)and LDL(68–70%in each year).All 3 priority goals were achieved by 47–52%of participants in any given ***,only 22%of participants achieved all 3 goals in each ***:A strategy of monitoring care and providing feedback was associated with high average yearly achievement of 3 priority secondary prevention goals,but the majority of trial participants did not persist in being at goal over *** registration number:NCT00091949.

关键词： prevention annually goals

世界贸易组织《贸易便利化协定》背景下的单一窗口

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海关与经贸研究 2021年第3期42卷 28-53页

作者： david Widdowson Bryce Blegen Geoff Short Gareth lewis Eduardo Garcia-Godos Mikhail Kashubsky 徐君(译) 谢昕宇(译) 张树杰(校) 澳大利亚查尔斯·斯图特大学海关与消费税研究中心国际海关大学世界海关组织PICARD咨询小组和科学委员会信任贸易联盟澳大利亚海关署法律处全球会计师事务所贸易便利化研究所国际海关大学网络秘书处海关总署国际司上海海关学院海关与公共管理学院上海海关学院党校工作部

本篇论文立足于一个研究项目的结果,而该研究旨在通过向贸易利益攸关方提供有助于澳大利亚建立服务于贸易单一窗口的视角,来支持澳大利亚政府的贸易便利化议程。此外,澳大利亚的报告回顾了公认权威的国际机构就这一问题颁布的标准和最... 详细信息

本篇论文立足于一个研究项目的结果,而该研究旨在通过向贸易利益攸关方提供有助于澳大利亚建立服务于贸易单一窗口的视角,来支持澳大利亚政府的贸易便利化议程。此外,澳大利亚的报告回顾了公认权威的国际机构就这一问题颁布的标准和最佳做法,包括世界贸易组织的《贸易便利化协定》(TFA)。这可能是自《贸易便利化协定》实施以来,第一个由主要发达贸易国的私营部门推动的单一窗口研究,该研究的一些方面在该协定更广阔的全球背景下似乎显现出相关性,而本文讨论的正是这些方面。本文结论是,所有TFA签署方都需要认真考虑其根据协定执行的优先事项。为此,本文提出了基于原始研究项目的系列结论,这些结论与TFA的所有签署成员都有关,无论它们处于什么样的发展水平。

关键词：贸易便利化单一窗口协调边境管理边境机构合作