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Pseudomonas aeruginosa-related effusive-constrictive pericarditis diagnosed with echocardiography:A case report

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World Journal of Clinical Cases 2022年第21期10卷 7577-7584页

作者： Jin-Ling Chen Dan-e Mei Cai-Gui Yu Zhi-Yu Zhao Department of echocardiography Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

BACKGROUND effusive-constrictive pericarditis(eCP)is an uncommon pericardial *** echocardiographic examination may provide helpful information not only for diagnosing but also for managing *** has various etiologies;however,Pseudomonas aeruginosa(***)infection has not been reported as a cause to ***,we present a rare case of eCP caused by *** infection,which was followed up using *** SUMMARY A 30-year-old man was admitted to our hospital with a 2-mo history of cough,dyspnea,bloating,palpitations,and lower-extremity *** patient was initially diagnosed with pericardial effusion by transthoracic *** of pericardial effusion was performed to relieve the clinical symptoms.A follow-up echocardiogram showed that the pericardial effusion had decreased;however,the right atrial pressure continued to increase,and signs of constrictive pericarditis were observed upon a more comprehensive ***,the diagnosis of eCP was established based on the comprehensive pre-and postpericardiocentesis echocardiographic *** urgent pericardectomy was subsequently performed,which significantly relieved the patient's clinical symptoms,and the signs of pericardial constriction on echocardiography *** effusion and pericardial culture showed growth of *** eCP induced by *** infection remains a rare *** presence of echocardiographic features of constrictive pericarditis after pericardiocentesis therapy is highly indicative of eCP.

关键词： effusive-constrictive pericarditis Pseudomonas aeruginosa infection echocardiography Case report

Output feedback control of pantograph–catenary system with adaptive estimation of catenary parameters

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Journal of Modern Transportation 2015年第4期23卷 252-261页

作者： e.Chater D.Ghani F.Giri M.Haloua LAII Lab EMI Med V University UNICAeN GREYC Lab UMR CNRS Normandie Universite'

With the increasing railway vehicle speed, pantograph--catenary （PAC） system has become an important part as its incidents still stand among the prin- cipal causes of railway traffic interruption. Indeed, when a rail vehicle moves, the pantograph should constantly press against the underside of the catenary. Nonetheless, it is difficult to get around the complexity of the physical interaction between the pantograph and the contact wire, which could deteriorate the quality of the electricity transfer. Thus, PAC system performances could dramati- cally be reduced because of bad current collection. Therefore, in this paper, we present an output feedback solution in order to design an active control of PAC system. The proposed solution is based on the backstepping control and an adaptive observer that estimates both the （unknown） catenary parameters and the system state. All synthesis steps are given and the closed-loop analysis shows asymptotic tracking behavior regardless of the time-vary- ing catenary stiffness. Furthermore, a numerical example shows that the PAC contact can be regulated with desired effect.

关键词： Transportation systems Periodic systemsanalysis Control of oscillations

Software Technology for e-Commerce era

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 159-163页

作者： Chen shing Chou e Toyou International Inc.,Taipei 100,China e-Toyou International Inc. Taipei 100 China

The rapid growth of Internet usage and electronic commerce (e commerce) applications will push traditional industries to transform their business models and to re engineer their information systems. This direction will give the software industry either great opportunities for their business growth or crucial challenges to their existence. This article describes two essential challenges the software industry will face and presents relevant new technologies that will be helpful for overcoming those challenges.

关键词： Software technology electronic commerce software industry software development domain knowledge knowledge oriented one to one IPR protection

estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis

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World Journal of Gastroenterology 2017年第37期23卷 6802-6816页

作者： Janaki K Iyer Mamta Kalra Anil Kaul Mark e Payton Rashmi Kaul Department of Biochemistry and Microbiology Oklahoma State University-Center for Health Sciences Department of Natural Sciences Northeastern State University Immatics US Inc Health Care Administration Oklahoma State University-Center for Health Sciences Department of Statistics Oklahoma State University

AIM To investigate gender-specific liver estrogen receptor(eR) expression in normal subjects and patients with hepatitis C virus(HCV)-related cirrhosis and hepatocellular carcinoma(HCC).MeTHODS Liver tissues from normal donors and patients diagnosed with HCV-related cirrhosis and HCV-related HCC were obtained from the NIH Liver Tissue and Cell Distribution System. The expression of eR subtypes, eRα and eRβ, were evaluated by Western blotting and real-time RT-PCR. The subcellular distribution of eRα and eRβ was further determined in nuclear and cytoplasmic tissue lysates along with the expression ofinflammatory [activated NF-κB and IκB-kinase(IKK)] and oncogenic(cyclin D1) markers by Western blotting and immunohistochemistry. The expression of eRα and eRβ was correlated with the expression of activated NF-κB, activated IKK and cyclin D1 by Spearman's correlation. ReSULTS Both eR subtypes were expressed in normal livers but male livers showed significantly higher expression of eRα than females(P e observed significantly higher m RNA expression of eRα in HCV-related HCC liver tissues as compared to normals(P eRβ in livers of HCV-related cirrhosis and HCV-related HCC subjects(P e protein level, there was a significantly higher expression of nuclear eRα in livers of HCV-related HCC patients and nuclear eRβ in HCV-related cirrhosis patients as compared to normals(P ermore, we observed a significantly higher expression of phosphorylated NF-κB and cyclin D1 in diseased livers(P ere was a positive correlation between the expression of nuclear eR subtypes and nuclear cyclin D1 and a negative correlation between cytoplasmic eR subtypes and cytoplasmic phosphorylated IKK in HCV-related HCC livers. These findings suggest that dysregulated expression of eR subtypes following chronic HCVinfection may contribute to the progression of HCVrelated cirrhosis to HCV-related *** Gender differences were observed in eR

关键词： estrogen receptor α estrogen receptor β Hepatitis C virus-related cirrhosis Hepatitis C virusrelated hepatocellular carcinoma Sex and gender Normal liver

Operator Splitting for Three-Phase Flow in Heterogeneous Porous Media

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Communications in Computational Physics 2009年第6期6卷 72-84页

作者： e.Abreu J.Douglas F.Furtado F.Pereira Instituto Nacional de Matematica Pura e Aplicada RJ 22460-320Brazil Department of Mathematics Purdue UniversityWest LafayetteIN 47907-1395USA Department of Mathematics University of WyomingLaramieWY 82071-3036USA Department of Mathematics and School of energy Resources University of WyomingLaramieWY 82071-3036USA

We describe an operator splitting technique based on physics rather than on dimension for the numerical solution of a nonlinear system of partial differential equations which models three-phase flow through heterogeneous porous *** model for three-phase flow considered in this work takes into account capillary forces,general relations for the relative permeability functions and variable porosity and permeability *** our numerical procedure a high resolution,nonoscillatory,second order,conservative central difference scheme is used for the approximation of the nonlinear system of hyperbolic conservation laws modeling the convective transport of the fluid *** scheme is combined with locally conservative mixed finite elements for the numerical solution of the parabolic and elliptic problems associated with the diffusive transport of fluid phases and the pressure-velocity *** numerical procedure has been used to investigate the existence and stability of nonclassical shock waves(called transitional or undercompressive shock waves)in two-dimensional heterogeneous flows,thereby extending previous results for one-dimensional flow *** experiments indicate that the operator splitting technique discussed here leads to computational efficiency and accurate numerical results.

关键词： Operator splitting three-phase flow heterogeneous porous media central differencing schemes mixed finite elements

Surgical management of uveitis-glaucoma-hyphema syndrome

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International Journal of Ophthalmology(english edition) 2020年第6期13卷 935-940页

作者： Abdelrahman M.elhusseiny Richard K.Lee William e.Smiddy Department of Ophthalmology Bascom Palmer Eye InstituteUniversity of Miami Miller School of MedicineMiamiFL 33136USA Department of Ophthalmology Kasr Al-AinySchool of MedicineCairo UniversityCairo 12611Egypt

AIM:To report outcomes of patients after intraocular lens(IOL)repositioning or exchange for the version of the uveitisglaucoma-hyphema(UGH)syndrome that does not include closed loop anterior chamber IOL(nUGH).MeTHODS:Chart review of patients with nUGH who underwent IOL repositioning or exchange by one surgeon were *** main outcome measures were best corrected visual acuity(BCVA)as a decimal fraction preoperatively and postoperatively after IOL repositioning or *** findings evaluated included the presence of uveitis,hyphema,elevated intraocular pressure(IOP),and other complications such as pigment dispersion or vitreous *** number of anti-inflammatory and glaucoma medications were assessed before and after IOL repositioning or ***:The study included 14 pseudophakic *** median time at the onset of contemporary UGH after cataract extraction and IOL implantation(Ce/IOL)was7.5 *** repositioning or exchange was performed at a mean duration of 8.1±4.7 mo(median:4 mo)after onset of *** mean BCVA was improved from 0.45±0.26 preoperatively after onset of UGH syndrome to 0.76±0.22(P=0.016)after IOL repositioning or *** the14 eyes,uveitis,elevated IOP,and hyphema were present preoperatively in 13,13,and 6 eyes,*** and hyphema resolved in all cases after IOL *** mean IOP was reduced from 26.4±4.5 mm Hg preoperatively to 14.7±4.9 postoperatively(P=0.01).The mean number of glaucoma medications used was reduced from 1.7±1.1 medications preoperatively to 0.8±1.08(P=0.04)***:IOL repositioning or exchange is an effective treatment in many cases for medically resistant contemporary UGH syndrome.

关键词： intraocular lens complications secondary glaucoma vitrectomy

emerging artificial intelligence applications in liver magnetic resonance imaging

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World Journal of Gastroenterology 2021年第40期27卷 6825-6843页

作者： Charles e Hill Luca Biasiolli Matthew D Robson Vicente Grau Michael Pavlides Department of engineering Science University of OxfordOxford OX37DQUnited Kingdom Radcliffe Department of Medicine University of OxfordOxford OX39DUUnited Kingdom MR Physics Perspectum LtdOxford OX42LLUnited Kingdom Department of engineering University of OxfordOxford OX37DQUnited Kingdom Oxford Centre for Clinical Magnetic Resonance Research Division of Cardiovascular MedicineRadcliffe Department of MedicineUniversity of OxfordOxford OX39DUUnited Kingdom Translational Gastroenterology Unit University of OxfordOxford OX39DUUnited Kingdom Oxford NIHR Biomedical Research Centre University of OxfordOxford OX39DUUnited Kingdom

Chronic liver diseases(CLDs)are becoming increasingly more prevalent in modern *** use of imaging techniques for early detection,such as magnetic resonance imaging(MRI),is crucial in reducing the impact of these diseases on healthcare *** intelligence(AI)algorithms have been shown over the past decade to excel at image-based analysis tasks such as detection and *** applied to liver MRI,they have the potential to improve clinical decision making,and increase throughput by automating *** Liver diseases becoming more prevalent in society,the need to implement these techniques to utilize liver MRI to its full potential,is *** this review,we report on the current methods and applications of AI methods in liver MRI,with a focus on machine learning and deep learning *** assess four main themes of segmentation,classification,image synthesis and artefact detection,and their respective potential in liver MRI and the wider *** provide a brief explanation of some of the algorithms used and explore the current challenges affecting the *** there are many hurdles to overcome in implementing AI methods in the clinic,we conclude that AI methods have the potential to positively aid healthcare professionals for years to come.

关键词： Liver diseases Magnetic resonance imaging Machine learning Deep learning Artificial intelligence Computer vision

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Kinesiology

Anticoagulation in simultaneous pancreas kidney transplantation - On what basis?

2011年

作者： Joseph e. Muscolino

来源：畅想之星图书光盘版（南... 评论

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World Journal of Transplantation 2020年第7期10卷 206-214页

作者： Jeevan Prakash Gopal Frank JMF Dor Jeremy S Crane Paul e Herbert Vassilios e Papalois Anand SR Muthusamy Imperial College Renal and Transplant Center Imperial College Healthcare NHS TrustHammersmith HospitalLondon W120HSUnited Kingdom Department of Surgery and Cancer Imperial CollegeLondon W120HSUnited Kingdom

BACKGROUND Despite technical refinements,early pancreas graft loss due to thrombosis continues to *** coagulation tests(CCT)do not detect hypercoagulability and hence the hypercoagulable state due to diabetes is left ***(TeG)is an in-vitro diagnostic test which is used in liver transplantation,and in various intensive care settings to guide *** is better than CCT because it is dynamic and provides a global hemostatic profile including *** To compare the outcomes between TeG and CCT(prothrombin time,activated partial thromboplastin time and international normalized ratio)directed anticoagulation in simultaneous pancreas and kidney(SPK)transplant *** A single center retrospective analysis comparing the outcomes between TeG and CCT-directed anticoagulation in SPK recipients,who were matched for donor age and graft type(donors after brainstem death and donors after circulatory death).Anticoagulation consisted of intravenous(IV)heparin titrated up to a maximum of 500 IU/h based on CCT in conjunction with various clinical parameters or directed by TeG *** loss due to thrombosis,anticoagulation related bleeding,radiological incidence of partial thrombi in the pancreas graft,thrombus resolution rate after anticoagulation dose escalation,length of the hospital stays and,1-year pancreas and kidney graft survival between the two groups were *** Seventeen patients who received TeG-directed anticoagulation were compared against 51 contemporaneous SPK recipients(ratio of 1:3)who were anticoagulated based on *** graft losses occurred in the TeG group,whereas 11 grafts(7 pancreases and 4 kidneys)were lost due to thrombosis in the CCT group(P=0.06,Fisher’s exact test).The overall incidence of anticoagulation related bleeding(hematoma/gastrointestinal bleeding/hematuria/nose bleeding/re-exploration for bleeding/post-operative blood transfusion)was 17.65%in the TeG group and 45

关键词： Anticoagulation Pancreas transplantation Thromboelastography Thrombosis Hypercoagulability