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养猪进展 2006年第1期 9-11页

作者： I. corrégé S. Dubroca Institut Technique du Porc La Motte au Vicomte Le Rheu Cedex France

有效的清洁和消毒程序降低了众多疾病的发生及其影响。然而不足的是，这样会耗费大量的时间而且成本较高。本文的研究目标就是为猪场确定清洁和消毒的最优程序。

关键词：消毒过程消毒程序最优程序

Alternative Control of Alternaria Brown Spot in Tangerine

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Agricultural Sciences 2020年第12期11卷 1217-1231页

作者： Antonio Manoel Da Silva Filho Élida Barbosa corrêa Alisson Queiroz Moura Juan Manuel Anda Rocabado Phytopathology Laboratory of the State University from Paraiba (UEPB) Lagoa Seca Brazil Department of Agricultural Engineering Federal University of Campina Grande (DEAG/UFCG) Campina Grande Brazil Center University Araras Dr. Edmundo Ulson Araras Brazil Laboratory of Electronic Microscopy Federal University of the Rec&#244 ncavo of Bahia (UFRB) Cruz das Almas Brazil

Alternaria brown spot is considered the main disease of tangerines in the State of Paraiba. The objective of work was to evaluate vegetal tinctures from bitter melon (Momordica charantia) and guava (Psidium guajava) leaves, as an alternative control for Alternaria brown spot in tangerine. The effects of vegetal tinctures were tested in leaves and fruits (detached) of tangerine “Dancy” inoculated with tangerine pathotype of Alternaria alternata. The effect of tinctures on mycelium growth and spore germination of the pathogen was tested. Tinctures at 20% concentration promoted reduction of disease severity. A reduction of 80% in the diameter of leaf lesions was observed for bitter melon tinctures and 75.3% for guava tinctures. In fruits, the reduction was 48.4% (bitter melon tinctures) and 43.3% (guava tinctures). Guava tinctures, starting at a concentration of 5%, inhibited 100% of mycelium growth of tangerine pathotype of A. alternata, while the use of bitter melon tinctures inhibited 100% of mycelium growth starting at a concentration of 10%. The greater sensitivity to tinctures observed when these were added to the culture medium when compared to inoculation in leaves and fruits may be explained due to the higher exposition of the pathogen to the active principle when the vegetal tinctures were added to the culture medium, than when tinctures were sprayed over the vegetal surface in fruits and leaves. The number of germinated spores decreases 76.7% and 82% when using tinctures from guava and bitter melon (20%). Tinctures from bitter melon and guava are potential tools for alternative management of the Alternaria brown spot in tangerine “Dancy”.

关键词： Alternaria alternata f. sp. citri Momordica charantia Psidium guajava Vegetal Extracts Vegetal Tinctures

Characterization of the Sexual Self- and Cross-Compatibility in Genotypes of Cacao

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American Journal of Plant Sciences 2018年第9期9卷 1794-1806页

作者： Samuel Martins de Jesus Branco Daniela Viana da Silva Uilson Vanderlei Lopes Ronan Xavier corrêa Universidade Estadual de Santa Cruz Ilhéus Brazil Centro de Pesquisas do Cacau (CEPEC/CEPLAC) Ilheus Brazil

Cacao is a tree crop of high economic importance and the subject of several studies aiming the genetic improvement of the species with the incorporation of characteristics that are agronomically important to create superior genotypes. In this context, this study aimed to characterize 22 genotypes of cacao for sexual compatibility, which is a trait that is strongly associated with yield. Additionally, we identify genotypes incompatible with clone TSH-1188 through controlled intercrosses, due to the great importance of this clone in cocoa breeding. Fifteen genotypes were characterized as self-incompatible and other seven as self-compatible, considering the retention index (20%) of self-pollinated flowers. Nine genotypes were characterized for the first time: CCN-16, COCA-3310, COCA-3370/5, EB-1017, IMC-119, IMC-97, LCTEEN-37A, NA-45, and UF-612. Cacao genotypes showed flower retention index ranging from 0.0% to 55.1% after 15 days of self-pollinations. The number of retained flowers varied after self-pollination of cacao genotypes at 1, 5 and 15 days after pollination. CCN-51, Catongo, CCN-10 and P-4B, were the genotypes with minor losses of flowers after 15 days of pollination, while IMC-119 and TSH-516 had 100% of loss of flowers between 1 and 5 days after pollination. Moreover, the flower retention index 15 days after cross-pollination with TSH-1188 ranged from 0.0% to 87.5% among the tested genotypes. The results of cross-pollinations identified two genotypes that are incompatibles, EB-1017 and IMC-119. This result is important for future allelic studies of incompatibility in cacao, because it might indicate that these genotypes share the same self-incompatibility allele(s). We conclude, therefore, that this study enable the characterization of this working collection of cocoa germplasm for sexual compatibility and this information is important for subsequent crosses between cacao genotypes.

关键词： Breeding System Pollination Retention Index Cocoa Germplasm Theobroma cacao

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用盲肠细菌培养物预防肉鸡沙门氏菌病

国外兽医学（畜禽传染病） 1994年第4期14卷 56-58页

作者： corr.,DE 付刚

用连续流式（ＣＦ）培养系统分离培养成年肉鸡盲肠中的细菌。本文评价了肉鸡口服ＣＦ培养物和乳糖后对鼠伤寒沙门氏菌的保护作用。雏鸡孵出当天用嗉囊管饲法接种ＣＦ培养物。日粮中添加５％的乳糖。３日龄时经口攻击１０＾４个鼠伤寒沙... 详细信息

用连续流式（ＣＦ）培养系统分离培养成年肉鸡盲肠中的细菌。本文评价了肉鸡口服ＣＦ培养物和乳糖后对鼠伤寒沙门氏菌的保护作用。雏鸡孵出当天用嗉囊管饲法接种ＣＦ培养物。日粮中添加５％的乳糖。３日龄时经口攻击１０＾４个鼠伤寒沙门氏菌，攻毒后７天评价沙门氏菌定居情况。本试验用培养４２－１９０天的ＣＦ培养物对刚出壳的雏鸡进行６次重复试验。与对照鸡比较，接种ＣＦ培养物和在日粮中添加乳糖的鸡。

关键词：鸡细菌培养物盲肠沙门氏杆菌病

Cytogenetic Investigation in Patients with Clinical Suspicion of Genetic Syndrome in Manaus, Brazil

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Journal of Pharmacy and Pharmacology 2022年第3期10卷 72-78页

作者： Débora Pinto Denise corrêa Benzaquem Rachel Cardoso Nunes Vânia Mesquita Gadelha Prazeres Cleiton Fantin Hospital Universitário Getúlio Vargas ManausAmazonas 69020-170Brasil Human Genetics Laboratory State University of AmazonasManausAmazonas 69065-001Brazil Federal University of Amazonas.Manaus Amazonas 69067-005Brazil

Chromosomal alterations can cause a number of diseases;therefore,early detection of these alterations is fundamental in the prevention and treatment of various *** this sense,the objective of this study was to perform cytogenetic analysis of patients with phenotypic characteristics not yet clarified in order to determine the frequency of chromosomal alterations in patients treated in the public health system in Manaus,Brazil.A total of 98 patients with clinical suspicion of genetic syndrome were referred to the public health system in Manaus,Amazonas *** analyses were performed from lymphocyte culture and subsequent *** data were obtained through referral files and chromosomal a *** the 98 karyotypes analyzed,65(66.3%)presented normal karyotype,18(18.4%)presented chromosomal alterations and 15(15.3%)were *** the alterations found,11(61.1%)corresponded to alterations of the numerical type and 7(38.9%)of the structural *** the chromosomal alterations identified,the one with the highest frequency was aneuploidy,which was significantly represented by 9 patients with Down’s syndrome,and different karyotypic mechanisms related to this syndrome were *** was also one case of deletion,one case of pericentric inversion,and two involving the sex *** etiological confirmation of congenital anomalies is extremely important for the patient’s prognosis,and it is necessary to invest in cytomolecular tests,such as FISH and microarray in order to increase the rate of diagnosis.

关键词： Karyotype chromosomes banding karyotypic formula Down’s syndrome

The Long Way from Complex Phenotypes to Genes: The Story of Rat Chromosome 4 and Its Behavioral Effects

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World Journal of Neuroscience 2014年第3期4卷 203-215页

作者： Gabriela Ferreira de Medeiros Fernanda Junkes corrêa María Elisa Corvino Geison de Souza Izídio André Ramos Laboratório de Genética do Comportamento Departamento de Biologia Celular Embriologia e Genética Universidade Federal de Santa Catarina Florianópolis Brazil

Quantitative trait loci (QTLs) mapping has been performed during the past decades in an attempt to identify genes, gene products and mechanisms underlying numerous quantitative traits. It’s a strategy based on natural variations in genes and gene products, which facilitates translation from animal models to human clinical conditions. Our team has shown that the inbred rat strains Lewis (LEW) and Spontaneously Hypertensive Rats (SHR) differ with respect to several emotionality- related behaviors, one of which (inner locomotion in the open field) was strongly influenced by a QTL (Anxrr16) on rat chromosome 4. Since then, several other studies not only corroborated the initial description of Anxrr16, but also extrapolated its effects to a broader context (rats from both sexes and regardless of the estrous cycle phase) and suggested that this same region influences other emotionality-related behaviors as well as alcohol intake. Other QTLs affecting neurobiological traits were also found on rat chromosome 4 and several candidate genes have been pointed out as possibly influencing those phenotypes. Altogether, these studies suggest that rat chromosome 4 constitutes an interesting target for the study of the molecular bases of anxiety and other traits related to emotional reactivity.

关键词： Rat Chromosome 4 QTL Anxrr16 Emotionality-Related Behaviors Alcohol Consumption Stress-Response

The generation and evolution of the Archean continental crust:The granitoid story in southeastern Brazil

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Geoscience Frontiers 2022年第4期13卷 144-164页

作者： Rodrigo S.Marimon Chris J.Hawkesworth Elton L.Dantas Rudolph A.J.Trouw Wilson Teixeira Peter C.Hackspacher Allen Fetter Ciro A.Ávila Silvia Volante Atlas V.corrêa Neto Everton M.Bongiolo Rodrigo Vinagre Maurício Simon Depto.de Geologia IGEOUniversidade Federal do Rio de JaneiroUFRJRio de JaneiroRJBrazil School of Earth Sciences University of BristolBristolUnited Kingdom Instituto de Geociências Universidade de BrasíliaUnBBrasíliaDFBrazil Instituto de Geociências Universidade de São PauloUSPSão PauloSPBrazil Instituto de Geociências e Ciências Exatas Universidade Estadual PaulistaRio ClaroSPBrazil Institute of Geology Mineralogy and GeophysicsRuhr-Universität BochumUniversitätsstraße 15044801 BochumGermany ISOTOPIA Lab School of EarthAtmosphere and EnvironmentMonash UniversityWellington RdClaytonVIC 3800Australia Programa de Pós-Graduação em Geociências IGUniversidade Federal do Rio Grande do SulUFRGSPorto AlegreRSBrazil

The Archean Eon was a time of geodynamic *** evidence of these transitions come from igneous/metaigneous rocks,which dominate cratonic segments *** data for granitoids from an Archean basement inlier related to the Southern S?o Francisco Craton(SSFC),are integrated with geochronological,isotopic and geochemical data on Archean granitoids from the *** rocks are divided into three main geochemical groups with different ages:(1)TTG(3.02–2.77 Ga);(2)mediumto high-K granitoids(2.85–2.72 Ga);and(3)A-type granites(2.7–2.6 Ga).The juvenile to chondritic(Hf-Nd isotopes)TTG were divided into two sub-groups,TTG 1(low-HREE)and 2(high-HREE),derived from partial melting of metamafic rocks similar to those from adjacent greenstone *** compositional diversity within the TTG is attributed to different pressures during partial melting,supported by a positive correlation of Dy/Yb and Sr/Zr,and batch melting *** proposed TTG sources are geochemically similar to basaltic rocks from modern island-arcs,indicating the presence of subduction processes concomitant with TTG ***~2.85 Ga to 2.70 Ga,the dominant rocks were K-rich *** are modeled as crustal melts of TTG,during regional metamorphism indicative of crustal *** compositional diversity is linked to:(i)differences in source composition;(ii)distinct melt fractions during partial melting;and(iii)different residual mineralogies reflecting varying P–T ***-collisional(~2.7–2.6 Ga)A-type granites reflect rifting in that they were closely followed by extension-related dyke swarms,and they are interpreted as differentiation or partial melting products of magmas derived from subduction-modified *** sequence of granitoid emplacement indicates subduction-related magmatism was followed by crustal thickening,regional metamorphism and crustal melting,and post-collisional extension,similar to that seen in younger Wilson *** is compelling evide

关键词： Granitoid petrogenesis Archean geodynamics Crustal evolution TTGs A-types Batch melting calculations

Polyphenols in Fruits and Vegetables and Its Effect on Human Health

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Food and Nutrition Sciences 2014年第11期5卷 1065-1082页

作者： Giuseppina Pace Pereira Lima Fabio Vianello Camila Renata corrêa Renê Arnoux da Silva Campos Milena Galhardo Borguini Department of Chemistry and Biochemistry Sao Paulo State UniversityUNESPBotucatuSao PauloBrazil Department of Comparative Biomedicine and Food Science University of PadovaPadovaItalia Department of Internal Medicine Botucatu Medical SchoolSao Paulo State UniversityUNESPBotucatuSao PauloBrazil

Polyphenols represent a group of chemical substances common in plants, structurally characterized by the presence of one or more phenol units. Polyphenols are the most abundant antioxidants in human diets and the largest and best studied class of polyphenols is flavonoids, which include several thousand compounds. Numerous studies confirm that they exert a protective action on human health and are key components of a healthy and balanced diet. Epidemiological studies correlate flavonoid intake with a reduced incidence of chronic diseases, such as cardiovascular disease, diabetes and cancer. The involvement of reactive oxygen species (ROS) in the etiology of these degenerative conditions has suggested that phytochemicals showing antioxidant activity may contribute to the prevention of these pathologies. The present review deals with phenolic compounds in plants and reports on recent studies. Moreover, the present work includes information on the relationships between the consumption of these compounds, via feeding, and risk of disease occurrence, i.e. the effect on human health. Results obtained on herbs, essential oils, from plants grown in tropical, subtropical and temperate regions, were also reported.

关键词： Fruits Vegetables Consume Effect on Human Phenolic Content Thermal Processing Absorption

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用变压吸附法生产低成本高纯氢

天然气化工(C1化学与化工) 1979年第6期 109-112页

作者： F.corr 曾祥焜

采用多床变压吸附法(PSA)来加工蒸汽转化过程中的高变产品气可以生产出纯度极高的氢气(图1)。这样一套设施比之包括高、低温变换,二氧化碳洗涤和甲烷化在内的习用设施,其建设费和操作费均较低。此外,所得的较高纯度的氢气(99.999%,而习... 详细信息

采用多床变压吸附法(PSA)来加工蒸汽转化过程中的高变产品气可以生产出纯度极高的氢气(图1)。这样一套设施比之包括高、低温变换,二氧化碳洗涤和甲烷化在内的习用设施,其建设费和操作费均较低。此外,所得的较高纯度的氢气(99.999%,而习用法制得的纯度为98%)又可以改进合成和加氢过程的经济效果。这是因为仅有极少量的惰性物质必须清除,有可能采用更大生产规模的装置,并且/或者可以采用低压操作。

关键词：变压吸附法转化炉高温变换

Visual Disorders Outcome after Endoscopic Endonasal Trans-Sphenoidal Surgery of Pituitary Macroadenomas

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International Journal of Otolaryngology and Head & Neck Surgery 2016年第3期5卷 134-140页

作者： Wissame El Bakkouri Picard Hervé Brice Dzidzinyo Abdellaoui Anis Boyeldieu Louise corré Alain Vignal Catherine Boucenna Malika Ayache Denis ENT Department Fondation Ophtalmologique Adolphe de Rothschild Paris France Clinical Research Unit Fondation Ophtalmologique Adolphe de Rothschild Paris France OPH Department Fondation Ophtalmologique Adolphe de Rothschild Paris France Radiological Department Fondation Ophtalmologique Adolphe de Rothschild Paris France

Objective: Describe the outcome of visual disorders after endonasal transsphenoidal (EET) surgery of pituitary macroadenomas with preoperative chiasmal compression. Patients and Methods: From 2009 to 2013, 225 patients underwent EET surgery for sellar tumor. Among them, 168 suffered from visual disorders induced by chiasmatic compression, of which 88 met the inclusion criteria for this study. Average duration of follow up was 1.8 yrs ± 0.4 yrs. All patients had sellar MRI before surgery and yearly postoperatively, visual acuity (VA) and/or visual field (VF) measurements before, 3 months after surgery and yearly postoperatively. Results: All tumors were macroadenomas with a mean preoperative MRI-estimated volume of 10.0 {plus minus} 9.07 cm3. Preoperative VA was impaired with an average of 0.43 ± 0.13 LogMAR (left eye) and 0.36 ± 0.14 LogMAR (right eye) and VF was disturbed in 99% ± 2% of the cases with the most frequent disorder being bitemporal hemianopsia (38 patients). Post-operatively, the mean residual MRI-estimated tumor volume was 3.15 ± 3.71 cm3. Mean tumor volume reduction was 62% ± 9% (p < 0.001). Optic chiasmal compression resolved in 72% ± 10% of the cases. Visual function improved in 86% ± 7% of cases (p < 0.001). Conclusion: Endoscopic endonasal management of pituitary gland neoplasms is effective to reduce tumor volume. This technique achieved significant visual improvement in the majority of cases presenting with chiasmal compression syndrome.

关键词： Pituitary Macroadenoma Visual Disorder Chiasm Compression Endoscopy Transsphenoidal