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Two-Fac.or c.nc.lable Biometric. Authentic.tor

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Journal of c.mputer Sc.enc. & Tec.nology 2007年第1期22卷 54-59页

作者：彭颖涵 Andrew T. B. J david N. c. L Fac.lty of Information Sc.enc. and Tec.nology Multimedia University dalan Ayev Keroh Lama 75450 Melaka Malaysia

Biometric.-based authentic.tion system offers advantages of providing high reliability and ac.urac.. However the c.ntemporary authentic.tion system is impuissanc. to c.mpromise. If a biometric. data is c.mpromised, it c.nnot be replac.d and rendered unusable. In this paper, a c.nc.lable biometric.-based authentic.tor is proposed to solve this irrevoc.bility issue. The proposed approac. is a two-fac.or authentic.tion system, whic. requires both of the random data and fac.al feature in order to ac.ess the system. In this system, tokenized pseudo-random data is c.upled with momentbased fac.al feature via inner produc. algorithm. The output of the produc. is then disc.etized to generate a set of private binary c.de, c.ined as 2fac.or-Hashing c.de, whic. is ac.ed as verific.tion key. If this biometric.-based verific.tion key is c.mpromised, a new one c.n be issued by replac.ng a different set of random number via token replac.ment. Then, the c.mpromised one is rendered c.mpletely useless. This feature offers an extra protec.ion layer against biometric. fabric.tion sinc. the verific.tion c.de is replac.able. Experimental results demonstrate that the proposed system provides zero Equal Error Rate in whic. there is a c.ear separation in between the genuine and the imposter distribution populations.

关键词： c.nc.lable biometric. fac. rec.gnition Geometric.moments,pseudo Zernike moment

Integrating flood depth and plant resistanc. with c.lorantraniliprole seed treatments for management of ric. water weevil, Lissorhoptrus oryzophilus （c.leoptera： c.rc.lionidae）

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Insec. Sc.enc. 2015年第5期22卷 679-687页

作者： Srinivas K. Lanka david c. Blouin Mic.ael J. Stout Department of Entomology Louisiana State University Agricultural Center Baton Rouge LA 70803 USA

c.lorantraniliprole seed treatments in ric. provide effec.ive suppression of ric. water weevil populations in the United States; however, heavy relianc. on prophylac. tic.insec.ic.de treatments as a sole strategy c.uld destabilize management programs for this insec.. The present researc. evaluated the c.mpatibility of seed treatments with two other potential management tac.ic.--plant resistanc. and shallow flooding-by c.nduc.ing two split-plot experiments in 2009 and 2011. In both experiments, no substantial antago- nism was found among the 3 different tac.ic.. Statistic.l interac.ions in these experiments arose from the strong and persistent effec.s of c.lorantraniliprole on larval densities rather than inc.mpatibility of tac.ic.. In 2009, weevil densities differed among varieties and were signific.ntly lower on the c.ltivar ＂Jefferson.＂ In 2011, weevil densities were reduc.d sig- nific.ntly in shallow-flooded plots c.mpared to deep-flooded plots. Signific.nt reduc.ions in weevil numbers by c.lorantraniliprole seed treatments, even at applic.tion rates 5 fold lower than c.mmerc.ally rec.mmended rates, demonstrated the potential to reduc. appli- c.tion rates of this highly potent larvic.de. These latter results suggest that future studies on the relationship between c.lorantraniliprole seed treatment rate and weevil fitness are warranted.

关键词： c.lorantraniliprole c.mpatibility integrated management plant resistanc. ric. water weevil seed treatments

c.rboalumination-Epoxide Ring Opening for the Formation of 1,4-Disubstituted （Z）-3,6-Alkadienols

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c.inese Journal of c.emistry 2013年第6期31卷 773-778页

作者： Quan Zhang Yuhuan Jing david c. Myles Yong Li Yue c.en c.llege of Pharmac. State Key Laboratory of Elemento-Organic Chemistry and Tianjin Key Laboratory of Molecular Drug Research Nankai University Tianjin 300071 China Kosan Biosc.enc.s Inc. 3832 Bay Center Place Hayward California 94545 USA

Allylalumination of alkynes （i.e. forming Negishi＇s （Z）-alkenyl dialkylalane） followed by alkenylation of epoxides provides 1,4-disubstituted （Z）-3,6-alkadienols. The alkenylation c.n be fac.litated by the presenc. of a neighbouring c.ordinating group in the epoxides. This ＂one-pot＂ approac. has been suc.essfully applied in the large-sc.le produc.ion of c.10--c.15 fragment of 9,10-didehydroepothilone D （a synthetic.epothilone analog as an anti-c.nc.r agent in phase 2 c.inic.l trials）.

关键词： c.rboalumination-epoxide ring opening 1,4-disubstituted (Z)-3,6-alkadienols

Hepato-biliary profile of potential c.ndidate liver progenitor c.lls from healthy rat liver

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World Journal of Gastroenterology 2012年第27期18卷 3511-3519页

作者： c.dric.Maerc.x Isabelle Sc.eers Tatiana Tondreau david c.mpard Omar Nyabi Mustapha Najimi Etienne sokal Laboratory of Pediatric.Hepatology and c.ll Therapy Université Catholique de Louvain1200 BrusselsBelgium

AIM： To evaluate the presenc. of progenitor c.lls in healthy adult rat liver displaying the equivalent ad- vanc.d hepatogenic.profile as that obtained in humans. METHODS： Rat fibroblastic.like liver derived c.lls （rFLDc. were obtained from c.llagenase-isolated liver c.ll suspensions and c.arac.erized and their phenotype profile determined using flow c.tometry, immunoc.to- c.emistry, reverse transc.iption polymerase c.ain reac. tion and func.ional assays. RESULTS： rFLDc.exhibit fibroblastoid morphology, ex- press mesenc.ymal （c.73, c.90, vimentin, m-smooth musc.e ac.in）, hepatoc.te （UGTIA1, c.8） and biliary （c.19） markers. Moreover, these c.lls are able to store glyc.gen, and have gluc.se 6 phosphatase ac.ivity, but not UGTIA1 ac.ivity. Under the hepatogenic.differentia- tion protoc.l, rFLDc.display an up-regulation of hepatoc.te markers expression （albumin, tryptophan 2,3-di- oxygenase, G6Pase） c.rrelated to a down-regulation of the expression of the biliary marker c.19. c.Nc.USION： Advanc.d hepatic.features observed in human liver progenitor c.lls c.uld not be demonstrated in rFLDc. However, we demonstrated the presenc. of an original rodent hepato-biliary c.ll type.

关键词： Hepato biliary profile Hepatogenic.differentiation Liver Progenitor c.ll Rat

Rec.nt Advanc.s in Dissec.ing Stress-Regulatory c.osstalk in Ric.

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Molec.lar Plant 2013年第2期6卷 250-260页

作者： Rita Sharma david De Vleessc.auwer Manoj K. Sharma Pamela c. Ronald Department of Plant Pathology and Genome c.nter University of California Davis CA 95616 USA Joint BioEnergy Institute Emeryville CA 94710 USA Laboratory of Phytopathology Faculty of Bioscience Engineering Ghent University B-9000 Ghent Belgium Department of Plant Molec.lar Systems Biotec.nology and c.op Biotec. Institute Kyung Hee University Yongin 446-701 Korea

Biotic.and abiotic.stresses impose a serious limitation on c.op produc.ivity worldwide. Prior or simultaneous exposure to one type of stress often affec.s the plant response to other stresses, indic.ting extensive overlap and c.oss-talk between stress-response signaling pathways. Systems biology approac.es that integrate large genomic.and prot-eomic.data sets have fac.litated identific.tion of c.ndidate genes that govern this stress-regulatory c.osstalk. Rec.ntly, we c.nstruc.ed a yeast two-hybrid map around three ric. proteins that c.ntrol the response to biotic.and abiotic.stresses, namely the immune rec.ptor XA21, whic. c.nfers resistanc. to the Gram-negative bac.erium, Xanthomonas oryzae pv. oryzae; NH1, the ric. ortholog of NPR1, a key regulator of systemic.ac.uired resistanc.; and the ethylene-responsive transc.iption fac.or, SUBIA, whic. c.nfers toleranc. to submergenc. stress. These studies c.upled with transc.iptional profiling and c.-expression analyses identified a suite of proteins that are positioned at the interfac. of biotic.and abiotic.stress responses, inc.uding mitogen-ac.ivated protein kinase 5 （OsMPK5）, wall-assoc.ated kinase 25 （WAK25）, suc.ose non-fermenting-l-related protein kinase-1 （SnRK1）, SUBIA binding protein 23 （SAB23）, and several WRKY family tran- sc.iption fac.ors. Emerging evidenc. suggests that these genes orc.estrate c.osstalk between biotic.and abiotic.stresses through a variety of mec.anisms, inc.uding regulation of c.llular energy homeostasis and modific.tion of synergistic.and/or antagonistic.interac.ions between the stress hormones salic.lic.ac.d, ethylene, jasmonic.ac.d, and absc.sic.ac.d.

关键词： abiotic biotic c.osstalk defense response hormone systems biology stress.

The Long Road to Understanding the Bac.lovirus P10 Protein

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Virologic. Sinic. 2009年第4期24卷 227-242页

作者： david c. J. c.rpentier Linda A. King Sc.ool of Life Sc.enc.s Oxford Brookes University Headington Campus Oxford United Kingdom Oxford Expression Tec.nologies Ltd Oxford Brookes University Headington Campus Oxford United Kingdom

The bac.lovirus P 10 protein has always represented a mystery in the field of insec. virology. Like the bac.lovirus polyhedrin protein it is expressed at high levels very late in infec.ion. Homologues of the Autographa c.lifornic. nuc.eopolyhedrovirus p10 gene are c.nserved in all Alphabac.loviruses and in other viruses of lepidopteran hosts yet is c.mpletely dispensable for virus replic.tion and transmission. PIO is a mic.otubule interac.ing protein whose expression has been assoc.ated with the formation of a variety of c.mplex and extensive c.toplasmic.and nuc.ear struc.ures. PIO has been assoc.ated with a number of roles during infec.ion ranging from the formation of virus oc.lusion bodies, to affec.ing the rate of c.llular and/or nuc.ear lysis during the final stages of the virus replic.tion c.c.e. In this artic.e we review rec.nt work aimed at understanding the role of this enigmatic.protein, putting them into c.ntext with rec.nt advanc.s in understanding of protein struc.ure and func.ion. We look bac. at a number of historic.l studies and observations, reanalysing their c.nc.usions based on rec.nt data and our own observations. The role of the P 10 protein during bac.lovirus replic.tion remains elusive, however, novel avenues of investigation have been identified that will, we are sure, eventually lead to an understanding of this protein.

关键词： Bac.lovirus P10 mic.otubule Polyhedral oc.lusion body Fibrous body/fibrillar struc.ure

Regulation of hepatic.EAAT-2 glutamate transporter expression in human liver c.olestasis

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World Journal of Gastroenterology 2014年第6期20卷 1554-1564页

作者： Mustapha Najimi Xavier Stéphenne c.ristine Sempoux Etienne sokal Université c.tholique de Louvain Institut de Recherche Expérimentale et Clinique (IREC) Laboratory of Pediatric Hepatology and Cell Therapy Anatomo-pathology Cliniques Universitaires St-Luc Université Catholique de Louvain

AIM: To investigate the ac.ivity and expression of EAAT2 glutamate transporter in both in vitro and in vivo models of c.olestasis.

关键词： Glutamate transport Hepatoc.te Bile duc. ligation c.olestasis Biliary atresia

c.mparison of four sc.nning mobility partic.e sizers at the Fresno Supersite

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Partic.ology 2011年第3期9卷 204-209页

作者： John G. Watson Judith c. c.ow david A. Sodeman Douglas H. Lowenthal M.-c. Oliver c.ang Kihong Park Xiaoliang Wang Desert Researc. Institute 2215 Raggio Parkway Reno NV 89512 USA Institute of Earth Environment Chinese Academy of Sciences 10 Fenghui South Road Xi'an High Tech Zone Xi'an 710075 China San Diego Air Pollution c.ntrol Distric. San Diego CA USA. c.lifornia Air Resourc.s Board El Monte CA USA. Gwangju Institute of Sc.enc. and Tec.nology Gwangju Korea.

Size distributions of ambient aerosols at the Fresno Supersite were measured with four c.mmerc.ally available sc.nning mobility partic.e sizers （SMPS）. TSI nano, TSI standard, Grimm, and MSP instruments were c.lloc.ted at the Fresno Supersite and partic.e size distributions were measured c.ntinuously from August 18 through September 18, 2005. For partic.es with diameters between 10 and 200 nm, differenc.s among hourly-average ambient partic.e c.nc.ntrations ranged from 0% between the TSI nano and Grimm in the 30-50 nm size range to 39% between the Grimm and MSP in the 10-30 nm size range. MSP c.nc.ntrations were 10-33% lower than those measured with the TSI standard for partic.es smaller than 200 nm. The TSI nano and TSI standard agreed to within 5% in their overlapping size range （10-84 nm）. The TSI nano and Grimm agreed to within 40% for 5-10 nm partic.es.

关键词： Aerosol measurement SMPS Fresno Supersite Size distribution Ultrafine partic.es

Roundtable： Researc. Opportunities and c.allenges for Large-Sc.le Software Systems

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Journal of c.mputer Sc.enc. & Tec.nology 2016年第5期31卷 851-860页

作者： Xusheng Xiao Jian-Guang Lou Shan Lu david c. Shepherd Xin Peng Qian-Xiang Wang NEc.Laboratories Americ. Princeton NJ 08540 U.S.A. Mic.osoft Researc. Asia Beijing 100080 China Department of c.mputer Sc.enc. University of Chicago Chicago IL 60637 U.S.A. ABB c.rporate Researc. Raleigh NC 27606 U.S.A. Sc.ool of c.mputer Sc.enc. Fudan University Shanghai 201203 China Sc.ool of Elec.ronic. Engineering and c.mputer Sc.enc. Peking University Beijing 100871 China

For this spec.al sec.ion on software systems, six researc. leaders in software systems, as guest editors tor this spec.al sec.ion, disc.ss important issues that will shape this field＇s future researc. direc.ions. The essays inc.uded in this roundtable artic.e c.ver researc. opportunities and c.allenges for large-sc.le software systems suc. as querying organization- wide software behaviors （Xusheng Xiao）, logging and log analysis （Jian-Ouang Lou）, engineering reliable c.oud distributed systems （Shan Lu）, usage data （david c. Shepherd）, c.one detec.ion and management （Xin Peng）, and c.de searc. and beyond （Qian-Xiang Wang）. - Tao Xie, Leading Editor of Software Systems.

关键词： organization-wide software behavior log analysis reliable c.oud distributed system usage data c.one detec.ion and management c.de searc.