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血管性眩晕和头晕诊断标准:Bárány协会前庭疾病分类委员会共识文件

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神经损伤与功能重建 2023年第12期18卷 683-690页

作者：凌霞(译) 吴月霞(译) 冯宇菲(译) 钟利群(译) 赵桂萍(译) 杨旭(审校) 王朝霞(审校) Ji-Soo Kim david e.newman-toker Kevin A.Kerber Klaus Jahn Pierre Bertholon John Waterston Hyung Lee Alexandre Bisdorff Michael Strupp 北京大学第一医院神经内科航天中心医院(北京大学航天临床医学院)神经内科北京中医药大学东直门医院脑病科韩国城南市首尔大学医学院首尔大学盆唐医院神经内科美国巴尔的摩约翰霍普金斯大学医学院神经病学系美国安娜堡密歇根大学健康系统神经病学系德国巴特艾布灵施恩诊所神经内科和德国眩晕与平衡障碍中心路德维希-马克西米利安-慕尼黑大学法国圣艾蒂安医院耳鼻咽喉科澳大利亚墨尔本阿尔弗雷德医院莫纳什神经科学系韩国大邱启明大学医学院脑研究所神经病学系卢森堡阿尔泽特河畔埃施医疗中心神经病学系德国路德维希-马克西米利安-慕尼黑大学神经病学系德国眩晕和平衡障碍中心

本文介绍了Bárány协会前庭疾病分类委员会制定的血管性眩晕和头晕的诊断标准。分类中包括由卒中或短暂性脑缺血发作以及孤立性迷路梗死/出血和椎动脉压迫综合征引起的眩晕/头晕。眩晕和头晕是后循环卒中最常见的症状之一。血管性眩晕... 详细信息

本文介绍了Bárány协会前庭疾病分类委员会制定的血管性眩晕和头晕的诊断标准。分类中包括由卒中或短暂性脑缺血发作以及孤立性迷路梗死/出血和椎动脉压迫综合征引起的眩晕/头晕。眩晕和头晕是后循环卒中最常见的症状之一。血管性眩晕/头晕可能是急性持续性(≥24 h)或短暂性(数分钟至<24 h)发作。对于出现急性前庭症状和其他中枢神经系统症状和体征,包括中枢性HINTS体征(头脉冲试验正常、方向改变的凝视诱发性眼震或明显的眼球反向偏斜)的患者,尤其是伴有血管危险因素的患者,应该考虑血管性眩晕/头晕的诊断。尽管孤立性迷路梗死尚无确诊方法,但在卒中风险增加的患者中应该考虑,如果急性单侧前庭功能丧失同时伴有或在随后的30 d内出现小脑前下动脉区域的缺血性卒中,则可以推测为孤立性迷路梗死。对于椎动脉压迫综合征的诊断,常需要典型的临床症状、体征及其血管受损的影像学或超声证据支持。

关键词：眩晕头晕失衡梗死卒中脑干小脑

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前庭体征的分类及检查方法:眼震及眼震样眼动Bárány学会国际前庭疾病分类委员会共识文件

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神经损伤与功能重建 2020年第12期15卷 683-698页

作者：焉双梅(译) 凌霞(译) 司丽红(译) 常丽英(审校) 杨旭(审校) Scott DZeggers Alexandre Bisdorff Michael von Brevern david SZee Ji-Soo Kim Nicolas Perez-Fernandez Miriam SWelgampola Charles CDella Santinahand david enewman-toker 航天中心医院(北京大学航天临床医学院)神经内科湖北文理学院附属医院襄阳市中心医院神经内科美国明尼苏达州罗切斯特市梅奥诊所神经内科卢森堡埃施emile Mayrisch医疗中心神经内科德国柏林大学附属夏洛特医院神经内科&私立神经内科美国马里兰州巴尔的摩约翰霍普金斯大学医学院神经内科韩国首尔国立大学盆唐医院首尔国立大学医学院神经内科西班牙马德里纳瓦拉大学耳鼻喉科澳大利亚悉尼大学中心临床学院皇家阿尔弗雷德王子医院临床神经科学研究所美国马里兰州巴尔的摩约翰霍普金斯大学医学院耳鼻咽喉头颈外科

本文介绍了Bárány学会国际前庭疾病分类委员会制定的各种类型眼震和眼震样眼动的分类和定义,用于前庭及神经系统疾病患者的评估,以利于临床工作及科学研究中对这些体征的识别和交流。文中对眼震多种属性和影响因素的相关术语进行了描... 详细信息

本文介绍了Bárány学会国际前庭疾病分类委员会制定的各种类型眼震和眼震样眼动的分类和定义,用于前庭及神经系统疾病患者的评估,以利于临床工作及科学研究中对这些体征的识别和交流。文中对眼震多种属性和影响因素的相关术语进行了描述和定义。首先基于临床现象学对眼震相关的复杂术语进行了系统整理,同时也进一步对其相关的解剖学、病理生理学和病因学进行描述,并对眼震和与其相鉴别的其他多种眼震样眼动(如扫视侵扰/扫视振荡)特征进行了总结。

关键词：眼震前庭疾病神经系统疾病病理生理学病因学科学研究解剖学扫视

Calcareous Nannoplankton Biostratigraphy of the Bartin Province,Western Black Sea,Turkey

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Acta Geologica Sinica(english edition) 2012年第6期86卷 1434-1446页

作者： Caner Kaya OZeR Vedia toker Department of Geological engineering Engineering and Architecture FacultyBozok University Graduate School of Natural and Applied Sciences Adiyaman University

Calcareous nannoplankton biostratigraphy has been performed on five sedimentary sections through the marine Akveren Formation from the Bartin region of northern Turkey, on the southern Black Sea coast. This new biostratigraphy provides an age for the formation of the early Campanian （nannofossil zone UC15aTp） to early Selandian （nannofossil zone NPS）, and highlights the presence of the Campanian/Maastrichtian, Cretaceous/Tertiary （K/T）, and Danian/Selandian boundaries in this intermediate palaeolatitude location. Micula murus was identified below the K/T boundary, but Micula prinsii and Nephrolithus frequens were not, which implies that the K/T boundary interval is not complete in the study area. These dates are in agreement with previous micropaleontological studies.

关键词： calcareous nannoplankton biostratigraphy Campanian Maastrichtian Danian,Selandian

An examination of the effect of loneliness on the innovative behavior of health science faculty students

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Chinese Medical Journal 2019年第2期132卷 171-182页

作者： Fadime Cinar Kerem toker Health Management Faculty of Health SciencesSabahattin Zaim UniversityIstanbul 34303Turkey Health Management Faculty of Health SciencesBezmialem Vakif UniversityIstanbul 34050Turkey

Background:Contributing to the innovative behavior of individuals in the health management process is a desirable condition for increased health institution *** relationship between the sense of loneliness and individual innovation behaviors has not been studied and relevant literature is extremely *** purpose of this research was to examine the effect of an individual's sense of loneliness on their innovative ***:The research was performed between January and October *** effects of loneliness feelings on the individual innovative behaviors of 451 health science faculty students were *** data were collected using the "Individual Information Form," the "individual innovation scale," and the "University of California Los Angeles loneliness scale." The reliability and validity of the scales were tested with Structural equation ***:It was found that the female participants showed exhibited more innovative behavior than the ***, there was no significant difference in the loneliness status of participants by gender.A group of 23-year-old individuals showed a significant difference in the risk taking dimension compared to other age ***-grade students had more points in the experimental openness and opinion leadership sub-dimension than the other *** was observed that the behavior is molded as the education level *** regression models showed that loneliness has a negative effect of -0.254 on experiential openness and the leadership of ideas, and has a negative effect of -0.216 on risk *** was no effect of the sub-dimensions of loneliness on change ***, on the individualistic behavior of physical loneliness, a -0.267 negative effect was *** loneliness has no effect on the sub-dimensions of individual ***, the total sense of loneliness was found to have a negative effect on total individual ***:The study result

关键词： Loneliness Innovative behavior Health science

Application of a continuous respiratory sound monitoring system in thoracic surgery

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The Journal of Biomedical Research 2021年第6期35卷 491-494页

作者： Hong Wang Alper toker Ghulam Abbas Le Yi Wang Department of Anesthesiology West Virginia UniversityMorgantownWV 26506USA Department of Cardiovascular and Thoracic Surgery West Virginia UniversityMorgantownWV 26506USA Department of Thoracic Surgery West Virginia UniversityMorgantownWV 26506USA Department of electrical and Computer engineering Wayne State UniversityDetroitMI 48202USA.

Dear editor,We would like to present a novel system for monitoring double-lumen tube(DTL)positions in thoracic surgery by respiratory sounds at the trachea and the bronchi,based on our previously described methodology,algorithms,and patented technology[1-2].Most thoracic surgeries require one-lung ventilation(OLV).A DLT or a bronchial blocker(BB)is the most common means for managing *** DLT or BB malposition is a critical issue that needs to be accurately and promptly detected to prevent the incidence of hypoxemia and unintended re-expansion of operated lung during OLV[3-4].A multi-center study of 2127 patients requiring OLV during thoracic surgery revealed that DLTs were used in 95%of patients with a malposition rate of 14%,and BBs were used in 5%of patients with a malposition rate of 33%[5].

关键词： thoracic surgery respiratory

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良性阵发性位置性眩晕诊断标准

中国全科医学 2017年第11期20卷 1275-1281页

作者： Michael von Brevern Pierre Bertholon Thomas Brandt Terry Fife Takao Imai Daniele Nuti david newman-toker 焉双梅张欢杨旭吴子明德国柏林Park-Klinik Weissensee神经科法国圣艾蒂安贝尔维尤医院耳鼻咽喉-头颈外科德国慕尼黑路德维希-马克西米利安大学临床神经科学研究所美国亚利桑那州凤凰城亚利桑那大学医学院巴罗神经病学研究所日本大阪大学研究生院耳鼻咽喉-头颈外科意大利锡耶纳大学耳鼻咽喉-头颈外科美国马里兰州巴尔的摩市约翰霍普金斯大学医学院神经科航天中心医院北京大学航天临床医学院神经内科北京市100049 中国人民解放军总医院耳鼻咽喉头颈外科眩晕诊疗中心北京市100853

Bárány学会前庭疾病分类委员会制定了良性阵发性位置性眩晕(BPPV)诊断标准,对BPPV可操作性的诊断标准进行了介绍,包括已明确的BPPV分型和新出现的、有争议的BPPV分型,反映了当前医师对BPPV的临床和病理机制的认识。可以预期,对BPPV的... 详细信息

Bárány学会前庭疾病分类委员会制定了良性阵发性位置性眩晕(BPPV)诊断标准,对BPPV可操作性的诊断标准进行了介绍,包括已明确的BPPV分型和新出现的、有争议的BPPV分型,反映了当前医师对BPPV的临床和病理机制的认识。可以预期,对BPPV的深入理解将进一步促进其分类的不断完善。

关键词：眩晕位置性眼震诊断标准

effect of latanoprost/timolol and dorzolamide/tiomolol on intraocular pressure after phacoemulsification surgery

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International Journal of Ophthalmology(english edition) 2011年第2期4卷 190-194页

作者： Haydar erdogan Ayse Vural Ozec Cengiz Caner Mustafa Ilker toker Mustafa Kemal Arici Aysen Topalkara Departments of Ophthalmology School of MedicineUniversity of Cumhuriyet

·AIM:To evalaute the effect of fixed-combination latanoprost 0.005%/timolol maleate 0.5% and dorzolamide hydrochloride 2%/timolol maleate 0.5% on postoperative intraocular pressure after phacoemulsification cataract surgery.·MeTHODS:This study is a prospective,randomized,double-masked and *** study included 90 eyes of 90 patients which were scheduled to have phacoemulsification *** were randomly assigned preoperatively to 1 of 3 groups (30 eyes of 30 patients).Two hour before surgery,the patients received one drop latanoprost/timolol (group 1),dorzolamide/timolol (group 2) and placebo (group 3,control group).The IOPs were measured at preoperative and postoperative 4,8,and 24 hours.·ReSULTS:The preoperative mean intraocular pressure was not statistically significant between both drug groups and control *** group 1 and 2,the postoperative mean IOP [group1:(14.03?à3.15)mmHg and group 2:(14.16?à4.43)mmHg] at 24 hours were significantly lower than the control group [(16.93?à3.70)mmHg,(P e postoperative mean IOP of group 1 [(14.90±3.69)mmHg] at 8 hours was significantly lower than the control group [(17.70?à3.89)mmHg,(P ere was no significant difference between group 2 [(16.16?à5.23)mmHg] and control group at 8 hours (P >0.05).·CONCLUSION:When compared with placebo,the use of preoperative fixed combination of latanoprost/timolol and dorzolamide/timolol is an effective method for preventing intraocular pressure elevation in 24 hours after phacoemulsification surgery,but did not completely prevent IOP spikes.·

关键词： dorzolamide/timolol latanoprost/timolol intraocular pressure phacoemulsification cataract surgery

Comparison of the effects of bevacizumab and ranibizumab injection on corneal angiogenesis in an alkali burn induced model

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International Journal of Ophthalmology(english edition) 2012年第4期5卷 448-451页

作者： Ayhan Dursun Mustafa Kemal Arici Feyza Dursun Ayse Vural Ozec Mustafa Ilker toker Haydar erdogan Aysen Topalkara Department of Ophthalmology School of MedicineCumhuriyet UniversitySivasTurkey

·AIM:To investigate the effects of bevacizumab and ranibizumab on corneal neovascularization in an alkali burn-induced model of corneal angiogenesis. ·MeTHODS:Fifteen Wistar-Albino rats were divided randomly into 3 groups after chemical cauterization of the cornea. The first group received a single dose of 0.1mL saline solution as a control group whereas second and third groups received a single dose of 2.5mg bevacizumab or 1mg ranibizumab by subconjunctival injection, respectively. After three weeks, the rat corneas were evaluated by biomicroscopy and corneal photographs were taken. The percentage of neovascularization area, length of the longest new vessel, corneal oedema and corneal opacity scores were assessed. ·ReSULTS:The analysis of digital photographs showed that the percentage of neovascularization area to the total corneal area, the length of the longest new vessel, corneal oedema and opacity scores were significantly lower in both study groups compared to the control group (P e percentage of corneal neovascularization area, the length of the longest new vessel and corneal opacity score were less with bevacizumab than ranibizumab. ·CONCLUSION:Subconjunctival bevacizumab and ranibizumab treatments may be effective methods in reducing corneal neovascularization. Furthermore, bevacizumab is more effective than ranibizumab in the inhibition of corneal neovascularization.

关键词： corneal neovascularisation bevacizumab ranibizumab

Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma

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International Journal of Ophthalmology(english edition) 2015年第5期8卷 985-990页

作者： Feyza Dursun Ayse Vural Ozec Huseyin Aydin Aysen Topalkara Ayhan Dursun Mustafa Ilker toker Haydar erdogan Mustafa Kemal Arici Department of Ophthalmology Cumhuriyet University School of Medicine Department of Biochemistry Cumhuriyet University School of Medicine

AIMTo investigate the oxidative stress status of the aqueous humor and serum of patients with pseudoexfoliation (PeX) syndrome and pseudoexfoliative glaucoma (PeG) and to measure paraoxonase (PON) and arylesterase (ARe) *** total of 78 patients were enrolled in the study, with 26 patients in each separate group. The patients were divided into three groups: the first group entailed PeX syndrome patients, while the second group consisted of patients with PeG and the third group involved patients with no additional systemic diseases, other than the diagnosis of cataract as control. Total oxidative stress (TOS), total antioxidant capacity (TAC), PON, and ARe levels in aqueous humor and serum were ***, PON and arylesterase levels in aqueous humor and serum of the PeX syndrome and PeG patients were significantly decreased compared with control group (Pes were higher in patients with PeX syndrome and PeG than controls (Pe levels of aqueous humor did not differ significantly between the PeX syndrome and PeG groupsCONCLUSIONThese findings are potentially of significance and add to the growing body of evidence for oxidative stress in PeX syndrome and PeG. Decreased antioxidant defense and increased oxidative stress system may play an important role in the pathogenesis of PeX syndrome and PeG.

关键词： pseudoexfoliation syndrome oxidative stress paraoxonase arylesterase