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近端指间关节掌腱膜挛缩治疗中早期的软组织分离术与筋膜切除术之后的马缰韧带松解术

中国美容整形外科杂志 2013年第1期24卷 I0018-I0018页

作者： Randall O. Croft Anthony A. Smith Brandon Cofalde Wdliam J. Casey Ⅲ Manna M. Rebecca Scott F. M. duncan 吕梦竹(译) 郭澍(译) 孙强(译) 魏峰(译) 高景恒(译) 美国亚利桑那州斯科茨代尔梅约诊所整形再造外科中心外科部及骨科中国医科大学附属第一医院整形外科《中国美容整形外科杂志》编辑部

背景与目的用马缰韧带松解术来治疗近端指间关节掌腱膜挛缩并不能解决手指动脉短缩及皮肤不足的问题，DigitWidget应用软组织分离的方法成功克服了这些问题。本研究将先行筋膜切除术再行马缰韧带松解术，与先行软组织分离术再行有效松... 详细信息

背景与目的用马缰韧带松解术来治疗近端指间关节掌腱膜挛缩并不能解决手指动脉短缩及皮肤不足的问题，DigitWidget应用软组织分离的方法成功克服了这些问题。本研究将先行筋膜切除术再行马缰韧带松解术，与先行软组织分离术再行有效松解，这两种方法在治疗近端指间关节掌腱膜挛缩的效果上进行了对比。方法作者在2001—2008年间比较了应用筋膜切除术联合马缰韧带松解与DigitWidget软组织分离术的治疗效果。

关键词：近端指间关节韧带松解术掌腱膜挛缩治疗效果膜切除术分离术软组织中早期

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K63-linked TAK1 Polyubiquitination at Lys-158 Residue is Required for TNFαand IL-1β-induced IKK/NF-κB and JNK/AP- 1 Activation

K63-linked TAK1 Polyubiquitination at Lys-158 Residue is Req...

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第八次全国医学遗传学学术会议(中华医学会2009年医学遗传学年会)

作者： YU Yang~(1,3),FAN Yi-hui~1,SUN Wen-jing~1,XIE Min~2,YANG Jian-hua~3,FU Song-bin~1 1 Laboratory of Medical Ce- netics,Harbin Medical University,Harbin 150081,China 2 Center for Cardiovascular Development,Department of Medicine,Baylor College of Medicine,Houston,Texas,USA 3 Texas Children’s Cancer Center,Department of Pediatrics,Dan L.duncan Cancer Center, Baylor College of Medicine,Houston,Texas,USA.

TAK1 plays an essential role in proinflammatory cytokine TNFαand IL-1β-induced IKK/NF-κB and JNK/AP-1 activation. Here we report that TNFαand IL-1βinduce K63-linked TAK1 polyubiquitination at the Lys-158 residue within the kinase domain. TRAF2 and TRAF6 act as the ubiquitin E3 ligases to mediate K63-linked TAK1 polyubiquitination at Lys-158 residue in vivo and in vitro.K63-linked TAK1 polyubiquitination at Lys-158 residue is required for TAK1-mediated IKK complex *** of TAK1-deficient mouse embryo fibroblast cells with TAK1 wild-type or a TAK1 mutant containing a lysine 158 to arginine mutation revealed the importance of this site in TNFαand IL-1β-mediated IKK/NF-kB and JNK/AP-1 activation as well as IL-6 gene *** finding is the first report that K63-linked polyubiquitination of a key kinase at a lysine site within its kinase domain is essential for its own kinase activation and its ability to mediate its downstream signal transduction pathways in response to TNFαand IL- 1βstimulation.

关键词： ubiquitination NF-κB TAK1 kinase TNF IL-1β IKK

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Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio david R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di Capodimonte Leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de Catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘Carlo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(ECAP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de Canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves

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Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei (Blyth, 1847) and description of a new species

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动物学研究 2020年第6期

作者： Christian Roos Kristofer M. Helgen Roberto Portela Miguez Naw May Lay Thant Ngwe Lwin Aung Ko Lin Aung Lin Khin Mar Yi Paing Soe Zin Mar Hein Margaret Nyein Nyein Myint Tanvir Ahmed Dilip Chetry Melina Urh E. Grace Veatch Neil duncan Pepijn Kamminga Marcus A. H. Chua Lu Yao Christian Matauschek Dirk Meyer Zhi-Jin Liu Ming Li Tilo Nadler Peng-Fei Fan Le Khac Quyet Michael Hofreiter Dietmar Zinner Frank Momberg

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