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Particulate Flow Simulation via a Boundary condition-Enforced Immersed Boundary-Lattice Boltzmann Scheme

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communications in computational Physics 2010年第4期7卷 793-812页

作者： J.wu c.Shu Department of Mechanical Engineering National University of Singapore10 Kent Ridge CrescentSingapore 119260

A boundary condition-enforced immersed boundary-lattice Boltzmannmethod (IB-LBM) for the simulation of particulate flows is presented in this paper. Ingeneral, the immersed boundary method (IBM) utilizes a discrete set of force densityto represent the effect of boundary. In the conventional IB-LBM, such force density ispre-determined, which cannot guarantee exact satisfaction of non-slip boundary condition. In this study, the force density is transferred to the unknown velocity correctionwhich is determined by enforcing the non-slip boundary condition. For the particulateflows, accurate calculation of hydrodynamic force exerted on the boundary of particlesis of great importance as it controls the motion of particles. The capability of presentmethod for particulate flows is depicted by simulating migration of one particle in asimple shear flow and sedimentation of one particle in a box and two particles in achannel. The expected phenomena and numerical results are achieved. In addition,particle suspension in a 2D symmetric stenotic artery is also simulated.

关键词： Lattice Boltzmann method immersed boundary method non-slip boundary condition particulate flow two-dimensional

Erosion rate of sand and mud mixtures

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International Journal of Sediment Research 2020年第6期35卷 563-575页

作者： chamil Perera Jarrell Smith Weiming wu david Perkey Anthony Priestas Department of civil and Environmental Engineering Clarkson University coastal and Hydraulics Laboratory US Army Corps of Engineers

Erosion of mixed cohesive and noncohesive sediments is studied using the erosion test instrument *** sediment mixtures are composed of well-sorted quartz sand(0.25-0.5 mm) and one of the three used muds:kaolinite,kaolinite-bentonite and Mississippi River *** mud contents cover from 0 to 100%.The measured data of erosion rate and bed shear stress are used to examine the segmented linear,nonlinear,and exponential erosion *** parameters of each erosion model are related to the physical properties of sediment mixtures,including clay fraction,mud fraction,mixture dry density,and mud dry *** is found that the three models can fit well with the data,and their parameters have strong relations with the mud fraction and mud dry density,to a less extent with the clay fraction,but not with the mixture dry density.

关键词： cohesive sediments Noncohesive sediments Sand and mud mixtures Segmented linear model Nonlinear model Exponential model

Thrombolysis for ischaemic stroke despite direct oral anticoagulation

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Stroke & Vascular Neurology 2024年第5期9卷 464-466页

作者： Jan c.Purrucker Thomas R.Meine Duncan Wilson Ying Xian Teddy Y.wu david J.Seiffge Department of Neurology Heidelberg University HospitalHeidelbergGermany Department of Neurology and Stroke Research center Bern Inselspital BernUniversity of BernBernSwitzerland New Zealand Brain Research Institute ChristchurchNew Zealand The University of Texas Southwestern Medical center DallasTexasUSA Department of Neurology Christchurch HospitalChristchurchNew Zealand

Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants(DOAcs)and a recent intake within the last 48hours in US and European ***,three observational studies now suggest safety of thrombolysis in patients with recent intake of DOAcs,and thus support previous experimental *** this perspective,the current evidence and practical consequences are discussed.

关键词： intake patients consequences

Microfluidic single cell analysis shows porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation

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中国病理生理杂志 2012年第11期 2086-2087页

作者： Patricia NGUYEN Divya NAG Preston D.LAVINGHOUSEZ Jordan R.PLEW Andrew S.LEE Bruno c.HUBER Won Hee LEE Patricia E.de ALMEIDA Jennfier LYONS Fumi IKENO Robert c.ROBBINS Michael T.LONGAKER Joseph c.wu Department of Medicine Division of Cardiovascular MedicineStanford University School of MedicineStanfordCA 94305-5101USA Department of Pediatrics Stanford University School of MedicineStanfordCA 94305-5101USA Department of Radiology Molecular Imaging ProgramStanford University School of MedicineStanfordCA 94305-5101USA Department of cardiothoracic Surgery Stanford University School of MedicineStanfordCA 94305-5101USA Department of Plastic Surgery Stanford University School of MedicineStanfordCA 94305-5101USA

AIM:Induced pluripotent stem cells(iPScs)hold great promise for the development of patient-specific therapies for cardiovascular ***,clinical translation will require preclinical optimization and validation of large a... 详细信息

关键词： iPSc cell Microfluidic single cell analysis shows porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation stem

MAPK signaling： A key element in plant defense response to insects

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Insect Science 2015年第2期22卷 157-164页

作者： christian Hettenhausen Meredith c. Schuman Jianqiang wu Kunming Institute of Botany Chinese Academy of Sciences Kunming China Max Planck Institute for chemical Ecology Hans-Knoell Str. 8 07745 Jena Germany

Insects have long been the most abundant herbivores, and plants have evolved sophisticated mechanisms to defend against their attack, In particular, plants can perceive specific patterns of tissue damage associated with insect herbivory. Some plant species can perceive certain elicitors in insect oral secretions （OS） that enter wounds during feeding, and rapidly activate a series of intertwined signaling pathways to orchestrate the biosynthesis of various defensive metabolites. Mitogen-activated protein kinases （MAPKs）, common to all eukaryotes, are involved in the orchestration of many cellular processes, including development and stress responses. In plants, at least two MAPKs, salicylic acid-induced protein kinase （SIPK） and wound-induced protein kinase （WlPK）, are rapidly activated by wounding or insect 0S; importantly, genetic studies us- ing transgenic or mutant plants impaired in MAPK signaling indicated that MAPKs play critical roles in regulating the herbivory-induced dynamics of phytohormones, such as jasmonic acid, ethylene and salicylic acid, and MAPKs are also required for transcriptional activation of herbivore defense-related genes and accumulation of defensive metabolites. In this review, we summarize recent developments in understanding the functions of MAPKs in plant resistance to insect herbivores.

关键词： defense FAc insect jasmonate mitogen-activated protein kinase (MAPK) plant-insect interaction

采用感受野优化与渐进特征融合的图像超分辨率算法

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西安交通大学学报 2025年第1期59卷 136-147页

作者：吴洪伍盖绍彦达飞鹏东南大学自动化学院 210096南京东南大学复杂工程系统测量与控制教育部重点实验室 210096南京

针对现有基于深度学习的超分辨率方法存在参数冗余以及难以学习到全局上下文信息、重建图像高频特征能力欠佳的问题,提出一种基于感受野优化与渐进特征融合的超分辨率网络(RPSRnet),其在单幅图像重建方面实现了较高的性能。该网络采用... 详细信息

针对现有基于深度学习的超分辨率方法存在参数冗余以及难以学习到全局上下文信息、重建图像高频特征能力欠佳的问题,提出一种基于感受野优化与渐进特征融合的超分辨率网络(RPSRnet),其在单幅图像重建方面实现了较高的性能。该网络采用像素注意力机制与大感受野卷积相结合的方式,设计两条渐进路径将输入表征为不同层次的特征抽象,增强网络捕获上下文信息的能力,同时减少了网络参数冗余。通过分层卷积和多重感受野分支,在保持轻量卷积的前提下,于分层的多路径上学习不同尺度的融合特征,增强网络重建边缘细节和复杂纹理特征的能力。实验结果表明:相比于先进算法,所提算法在基准测试集Set5上的峰值信噪比达到32.47 dB,在测试集Set14上达到28.81 dB,优于现有的先进算法,且网络参数更少,实现了9%的参数缩减,从而验证了算法的有效性。

关键词：超分辨率注意力机制感受野优化特征融合

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Longwall automation: Delivering enabling technology to achieve safer and more productive underground mining

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International Journal of Mining Science and Technology 2015年第6期25卷 865-876页

作者： Ralston Jonathon c. Reid david c. Dunn Mark T. Hainsworth david W. coal Mining Research Program CSIRO Energy

The ongoing need to deliver improved safety, productivity and environmental benefit in coal mining presents an open challenge as well as a powerful incentive to develop new and improved solutions. This paper assesses the critical role that enabling technologies have played in the delivery of remote and automated capability for longwall mining. A brief historical account is given to highlight key technical contributions which have influenced the direction and development of present-day longwall technology. The current state of longwall automation is discussed with particular attention drawn to the technologies that enable automated capability. Outcomes are presented from an independently conducted case study that assessed the impact that cSIRO＇s LASc longwall automation research has made to the longwall mining industry in Australia. Importantly, this study reveals how uptake of this innova- tive technology has significantly benefitted coal mine productivity, improved working conditions for personnel and enhanced environmental outcomes. These benefits have been widely adopted with cSIRO automation technology being used in 60 per cent of all Australian underground operations. International deployment of the technology is also emerging. The paper concludes with future challenges and opportunities to highfight the ongoing scope for longwall automation research and development.

关键词： Safety Productivity Environment Mining automation Longwall mining Remote mining

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Asymptotic Marginal Tax Rate of Individual Income Tax in china

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Economic and Political Studies 2014年第2期2卷 121-138页

作者： ZHENYA LIU wu YANG david DIcKINSON the School of Finance Renmin University of China he Department of Economics University of Birmingham the School of International Trade and Economics Central University of Finance and Economics of China the Department of Economics University of Birmingham

This paper examines the asymptotic marginal rate of individual income tax which maximizes china's social welfare through numerical simulation based on the elasticity of china's labor supply, income distribution and the social objectives of redistribution in accordance with the optimal direct taxation theory. Taking advantage of the optimal direct taxation model with consideration of the income effect, it comes to the conclusion that combined with china's reality, the asymptotic marginal rate of individual labor income tax in china should be between 35% and 40%.

关键词： reform of individual income tax asymptotic marginal tax rate optimal direct taxation theory

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Fruit Fly as a Model Organism for Blood-Brain Barrier Penetration and Infectious Disease in the Nanomedical Niche

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Journal of Bionic Engineering 2020年第3期17卷 553-569页

作者： Victoria Meng-Ting wu Vuk Uskokovic MP Biomedicals 9 GoddardIrvineCA 92618USA Department of Mechanical and Aerospace Engineering University of CaliforniaEngineering Gateway 4200Irviney CA 92697USA

Drosophila melanogaster,*** common fhiit fly,is a simple organism that may give a rapid,high-throughput response in regard to the therapeutic efficacy of nanoparticles and drugs,while circumventing the high environmental and monetary cost of today's typical in vivo assays involving more complex animals,along with the immeasurable suffering imposed onto *** we give the progress report on our effort to turn *** into a model organism for the in vivo testing of Blood-Brain Barrier(BBB)penetration of nanoparticles and the treatment of infectious *** show that orally ingested superparamagnetic nanoparticles successfully cross the BBB in *** and localize to the optic lobes of the third instar larval brain,while causing no adverse effects to the invertebrate *** also show that both orally ingested calcium phosphate nanoparticles and biofilm-forming *** localize to the Drosophila crop,the food storage organ of the fly,which shrinks in response to *** model does not induce mortality consequential to infection and the effects of the internalization and proliferation of the microbes are evaluable by measuring the crop parameters,including fluorescence intensity and *** development of these two models could simplify the preclinical testing of medical treatments and of pharmaceutical agents for neurological and infectious disease,while ensuring robust and reliable levels of statistical significance at low cost.

关键词： animal model calcium phosphate in vivo iron oxide nanoparticle