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耳内镜下镫骨手术治疗耳硬化症疗效探讨

中华耳科学杂志 2024年第4期22卷 617-621页

作者：温立婷李旭曾晓霞林曾萍赵达鹏胡田勇曾宪海深圳市龙岗区耳鼻咽喉医院耳鼻咽喉科深圳市耳鼻咽喉研究所深圳518172 解放军第九八四医院耳鼻喉科

目的探讨耳内镜下镫骨手术治疗耳硬化症的临床疗效。方法回顾性选取2018年1月至2020年12月深圳市龙岗区耳鼻咽喉医院耳外科收治的耳内镜下行镫骨手术耳硬化症患者85例,分析患者一般资料、临床疗效、随访结果。结果85例患者均于耳内镜下... 详细信息

目的探讨耳内镜下镫骨手术治疗耳硬化症的临床疗效。方法回顾性选取2018年1月至2020年12月深圳市龙岗区耳鼻咽喉医院耳外科收治的耳内镜下行镫骨手术耳硬化症患者85例,分析患者一般资料、临床疗效、随访结果。结果85例患者均于耳内镜下顺利完成手术。右耳后鼓室暴露难度、鼓索神经操作例数均高于左耳,差异均有统计学意义(P0.05);右耳术后眩晕、味觉障碍、迟发性面瘫与左耳比较,差异无统计学意义(P>0.05),右耳术后并发症总例数高于左耳,差异有统计学意义(P0.05)。术后平均气导阈值、平均气骨导差值均低于术前(P0.05)。结论耳内镜下镫骨手术治疗耳硬化症安全有效,创伤小、视野清晰。右耳镫骨手术中视野暴露较困难,鼓索神经损伤率增加。

关键词：耳硬化症耳内镜手术镫骨手术

Evaluating Functions of Reservoirs'Storage Capacities and Locations on Daily Peak Attenuation for Ganjiang River Basin Using Xinanjiang Model

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Chinese Geographical Science 2016年第6期26卷 789-802页

作者： DU Jinkang ZHENG dapeng XU Youpeng hu Shunfu XU Chongyu School of Geographic and Oceanographic Sciences Nanjing UniversityNanjing 210093China Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application Nanjing 210023China Anhui Electric Power Design Institute of China Energy and Electricity Construction Group Hefei 230601China Department of Geography Southern Illinois University EdwardsvilleEdwardsville IL 62026USA State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan 430072China Department of Geosciences University of OsloN-0316 Oslo 1047 BlindernNorway

Flooding is the most prevalent and costly natural disaster in the world and building reservoirs is one of the major structural measures for flood control and management. In this paper, a framework was proposed to evaluate functions of reservoirs′ locations and magnitudes on daily peak flow attenuation for a large basin of China, namely Ganjiang River Basin. In this study, the Xinanjiang model was adopted to simulate inflows of the reservoirs and flood hydrographs of all sub-catchments of the basin, and simple reservoir operation rules were established for calculating outflows of the reservoirs. Four reservoirs scenarios were established to analyze reservoirs′ locations on daily peak flow attenuation. The results showed that: 1) reservoirs attenuated the peak discharges for all simulated floods, when the flood storage capacities increase as new reservoirs were built, the peak discharge attenuation by reservoirs showed an increasing tendency both in absolute and relative measures; 2) reservoirs attenuated more peak discharge relatively for small floods than for large ones; 3) reservoirs reduced the peak discharge more efficiently for the floods with single peak or multi peaks with main peak occurred first; and 4) effect of upstream reservoirs on peak attenuation decreased from upper reaches to lower reaches; upstream and midstream reservoirs played important roles in decreasing peak discharge both at middle and lower reaches, and downstream reservoirs had less effect on large peak discharge attenuation at outlet of the basin. The proposed framework of evaluating functions of multiple reservoirs′ storage capacities and locations on peak attenuation is valuable for flood control planning and management at basin scale.

关键词： reservoir peak flow Xinanjiang model reservoir operation Ganjiang River Basin

Double-induced-mode integrated triboelectric nanogenerator based on spring steel to maximize space utilization

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Nano Research 2016年第11期9卷 3355-3363页

作者： Guanlin Liu Hengyu Guo Lin Chen Xue Wang dapeng Wei Chenguo hu Department of Applied Physics Chongqing University Chongqing 400044 China Chongqing Engineering Research Center of Graphene Film Manufacturing Chongqing 401329 China

Integrated multilayered triboelectric nanogenerators （TENGs） are an efficient approach to solve the insufficient energy problem caused by a single-layered TENG for achieving high output power density. However, most integrated multilayered TENGs have a relatively large volume. Here, a double-induced-mode integrated triboelectric nanogenerator （DI-TENG） based on spring steel plates is presented as a cost-effective, simple, and high-performance device for ambient vibration energy harvesting. The unique stackable rhombus structure, in which spring steel plates act both as skeletons and as electrodes, can enhance the output performance and maximize space utilization. The DI-TENG with five repeated units in a volume of 12 cm × 5 cm × 0.4 cm can generate a short-circuit current of 51 μA and can transfer charges of 1.25 μC in a half period. The contrast experiment is conducted systematically and the results have proved that the DI-TENG has a great advantage over the single-induced-mode TENG （SI-TENG） with only one side of a friction layer on its electrode. Besides, the DI-TENG can easily power a commercial calculator and can be used as a door switch sensor.

关键词： triboelectric nanogenerator double-induced-mode spring steelstackable rhombus structure

小波去噪改进GM(1,1)模型在高速公路变形监测中的应用

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地理空间信息 2024年第10期22卷 96-99页

作者：李瑞红刘大鹏胡书友广东省测绘工程有限公司广东广州510700

针对灰色GM(1,1)模型在变形监测数据建立预测模型精度较低的问题,采用小波阈值去噪与改进灰色模型的组合模型。首先介绍了小波阈值去噪方法;其次介绍了2+种灰色模型,在背景值公式中引入辛普森公式建立了基于背景值优化的改进灰色模型;... 详细信息

针对灰色GM(1,1)模型在变形监测数据建立预测模型精度较低的问题,采用小波阈值去噪与改进灰色模型的组合模型。首先介绍了小波阈值去噪方法;其次介绍了2+种灰色模型,在背景值公式中引入辛普森公式建立了基于背景值优化的改进灰色模型;最后以高速公路路基沉降监测点为例进行数据分析,将原始高速公路路基变形监测数据进行小波阈值去噪处理,通过信噪比和均方差确定小波基函数Sym3,分解层数为1层;基于传统GM(1,1)模型、新陈代谢灰色模型、小波去噪结合改进GM(1,1)模型、小波去噪结合改进新陈代谢灰色模型4种计算方案进行预测对比。实验结果表明,基于小波去噪的改进灰色优化模型的预测精度最高。验证了小波去噪的改进新陈代谢灰色模型更加贴合本次高速公路路基沉降的变形趋势。

关键词：高速公路路基变形监测小波阈值去噪背景值优化

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钢种补偿在冷轧高强钢厚度控制中的应用

钢铁研究 2017年第1期45卷 47-49页

作者：李志强胡大鹏李生存李保卫石峰首钢京唐钢铁联合有限责任公司冷轧作业部河北唐山063200

酸轧产线生产高强钢时,X射线测厚仪测出的带钢厚度和实际厚度有明显偏差,容易产生批量厚度不符的质量事故。分析了厚度偏差产生的原因,推导出了厚度离线钢种补偿的方法。该方法在产线应用后,X射线测厚仪测出的高强钢厚度偏差小于0.01 mm... 详细信息

酸轧产线生产高强钢时,X射线测厚仪测出的带钢厚度和实际厚度有明显偏差,容易产生批量厚度不符的质量事故。分析了厚度偏差产生的原因,推导出了厚度离线钢种补偿的方法。该方法在产线应用后,X射线测厚仪测出的高强钢厚度偏差小于0.01 mm,满足了对高强钢厚度精度控制的要求。

关键词： X射线测厚仪钢种补偿厚度偏差高强钢

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317L不锈钢在南海海水中的服役风险

腐蚀与防护 2024年第1期45卷 41-46页

作者：李慧心李大朋胡丽华王毛毛张玉楠王修云中海油研究总院有限责任公司北京100028 安科工程技术研究院(北京)有限公司北京102209 北京科技大学新材料技术研究院北京100083

为了评价南海近海海域317L不锈钢的服役性能,保障水下油气生产设施安全运行,开展了天然海水腐蚀试验,结合电化学测试及腐蚀形貌观察、微生物检测等手段,表征了317L不锈钢服役过程中的腐蚀特征及耐蚀性变化。结果表明:在南海近海海域滞... 详细信息

为了评价南海近海海域317L不锈钢的服役性能,保障水下油气生产设施安全运行,开展了天然海水腐蚀试验,结合电化学测试及腐蚀形貌观察、微生物检测等手段,表征了317L不锈钢服役过程中的腐蚀特征及耐蚀性变化。结果表明:在南海近海海域滞留环境中长期服役的317L不锈钢存在点蚀风险,不锈钢钝化膜溶解与修复的动态平衡在Cl-及微生物的共同作用下遭到破坏,腐蚀闭塞电池的自催化效应导致蚀坑内的金属基体活化溶解加速,点蚀风险增加。

关键词： 317L不锈钢滞留海水腐蚀行为服役风险自催化效应

基于GMS摩擦力补偿和干扰观测器的高精度速度控制

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国外电子测量技术 2024年第5期43卷 171-178页

作者：刘玉章赵志刚刘虎毛大鹏中国科学院长春光学精密机械与物理研究所长春130033 中国人民解放军63895部队孟州454750

为了降低机械轴系摩擦力扰动对于伺服控制器在低速运动控制精度的影响,进一步提高传统伺服控制器对于稳定平台的控制能力,提出了一种基于广义Maxwell滑动(generalized Maxwell-slip,GMS)摩擦力模型前馈和干扰观测器的高精度摩擦力补偿... 详细信息

为了降低机械轴系摩擦力扰动对于伺服控制器在低速运动控制精度的影响,进一步提高传统伺服控制器对于稳定平台的控制能力,提出了一种基于广义Maxwell滑动(generalized Maxwell-slip,GMS)摩擦力模型前馈和干扰观测器的高精度摩擦力补偿方案。首先在传统控制基础上引入GMS摩擦模型前馈补偿对摩擦扰动进行初步的补偿;然后,通过加入干扰观测器,对残余扰动及其他扰动进行第2次的抑制。利用实物平台对控制方法的低速运动性能进行了测试,对比设计的控制算法和传统PI控制器的控制结果,验证提出的控制策略抑制摩擦扰动的效果。结果表明,基于GMS摩擦力前馈和干扰观测器的控制方案有效的补偿了摩擦非线性、模型不确定性等因素对于控制系统的影响。新方法可将稳定平台低速运动时的控制误差降低到0.015°/s,在实际工程中具有较高的应用价值。

关键词：伺服控制摩擦力辨识摩擦力补偿干扰观测器运动控制

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缓释氮肥运筹对麦后直播棉熟相的影响

扬州大学学报（农业与生命科学版） 2019年第5期40卷 91-96页

作者：芮秋治李亚兵胡大鹏徐景丽刘媛媛田巧凤张祥陈源陈德华扬州大学江苏省作物遗传生理重点实验室江苏扬州225009 中国农业科学院棉花研究所/棉花生物学国家重点实验室河南安阳455000

以早熟棉品种"中棉所50"为材料,采用小麦后直播的种植方式,设置不同缓释氮施用量(45、90和135 kg·hm-2)和不同施用时期(2、4叶期),研究缓释氮肥运筹对小麦后直播棉吐絮和熟相的影响。结果表明:两年施氮90 kg·hm-2并于2叶期或4叶期施... 详细信息

以早熟棉品种"中棉所50"为材料,采用小麦后直播的种植方式,设置不同缓释氮施用量(45、90和135 kg·hm-2)和不同施用时期(2、4叶期),研究缓释氮肥运筹对小麦后直播棉吐絮和熟相的影响。结果表明:两年施氮90 kg·hm-2并于2叶期或4叶期施用产量最高。在2叶期施用处理下,吐絮率高且更为集中。2017年使用脱叶催熟剂后10月8日~11月2日的吐絮强度为1.0~1.1个·(m2·d)-1,对照仅为0.8个·(m2·d)-1;且最终吐絮率均在90%以上。脱叶催熟前黄叶率17%~19%,主茎红茎比67%~70%,上部倒1果枝红茎比为53%~60%,倒2~4果枝红茎比在71%~79%范围内则是产量高和吐絮多的熟相反映。相关分析表明,黄叶率、主茎红茎比、上部4台果枝红茎比与吐絮率均呈极显著线性正相关;而始絮期(9月23日)的黄叶率、主茎红茎比、上部4台果枝红茎比与8月30日~10月8日吐絮强度呈极显著开口向下抛物线关系。说明吐絮期保持适宜的黄叶率、主茎和上部4台果枝红茎比有利于集中吐絮。综合而言, 2、4叶期适宜的缓释氮施用有利于提高产量,而2叶期施用又能形成合理的熟相,从而实现集中吐絮,为机械化采收奠定基础。

关键词：小麦后直播棉缓释氮肥运筹熟相集中吐絮

Telencephalin protects PAJU cells from amyloid beta protein-induced apoptosis by activating the ezrin/radixin/moesin protein family/phosphatidylinositol-3-kinase/protein kinase B pathway

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Neural Regeneration Research 2012年第28期7卷 2189-2198页

作者： Heping Yang dapeng Wu Xiaojie Zhang Xiang Wang Yi Peng Zhiping hu Department of Neurology Shangrao No.5 People's Hospitalthe Second Affiliated Hospital of Nanchang UniversityShangrao 334000Jiangxi ProvinceChina Department of Neurology Ruikang Hospital Affiliated to Guangxi Traditional Chinese Medical UniversityNanning 530011Guangxi Zhuang Autonomous RegionChina Department of Neurology Xiangya Second HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina Department of Psychiatry Xiangya Second HospitalCentral South UniversityChangsha 410011Hunan ProvinceChina

Telencephalin is a neural glycoprotein that reduces apoptosis induced by amyloid beta protein in the human neural tumor cell line PAJU. In this study, we examined the role of the ezrin/radixin/moesin protein family/phosphatidylinositol-3-kinase/protein kinase B pathway in this process. Western blot analysis demonstrated that telencephalin, phosphorylated ezrin/radixin/moesin and phosphatidylinositol-3-kinase/protein kinase B were not expressed in PAJU cells transfected with empty plasmid, while they were expressed in PAJU cells transfected with a telencephalin expression plasmid. After treatment with 1.0 nM amyloid beta protein 42, expression of telencephalin and phosphorylated phosphatidylinositol-3-kinase/protein kinase B in the transfected cells gradually diminished, while levels of phosphorylated ezrin/radixin/moesin increased. In addition, the high levels of telencephalin, phosphorylated ezrin/radixin/moesin and phosphatidylinositol-3-kinase/protein kinase B expression in PAJU cells transfected with a telencephalin expression plasmid could be suppressed by the phosphatidylinositol-3-kinase inhibitor LY294002. These findings indicate that telencephalin activates the ezrin/radixin/moesin family/phosphatidylinositol-3-kinase/protein kinase B pathway and protects PAJU cells from amyloid beta protein-induced apoptosis.

关键词： telencephalin/intercellular adhesion molecule 5 amyloid beta protein ezrin/radixin/moesin familyproteins/phosphatidylinositol-3-kinase/protein kinase B signal transduction neural regeneration