检索结果-南通市图书馆

Genes & Diseases 2024年第3期11卷 98-101页

作者： Zishuai Wang Yilong Yao Xinhua Hou danyang fan Yanwen Liu Adeyinka Abiola Adetula Yalan Yang kui Li Zhonglin Tang Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong518000China Kunpeng Institute of Modern Agriculiture at Foshan Chinese Academy of Agricultural SciencesFoshanGuangdong528226China GuangXi Engineering Centre for Resource Development of Bama Xiang Pig BamaGuangxi 547500China Institute of Animal Science Chinese Academy of Agricultural SciencesBeijing100193China

Aerobic exercise training alters gene expression in skeletal muscle,and miRNAs significantly contribute to motion ***,the molecular mechanisms by which miRNAs regulate the response to exercise training are not well ***,we found that the abundance of miR-378a-3p in skeletal muscle significantly decreased after exercise ***-378a-3p knockout mice showed increased insulin sensitivity,insulin-mediated glucose uptake.

关键词： skeletal miR uptake

Advances in friction of aluminium alloy deep drawing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Friction 2024年第3期12卷 396-427页

作者： Yiren GAO Hongxia LI danyang ZHAO Minjie WANG Xiaobo fan School of Mechanical Engineering Dalian University of TechnologyDalian 116023China

Broad use of lightweight aluminium alloy parts in automobile manufacturing,aerospace,electronic communication,and rail transit is mainly formed through deep drawing *** drawing friction is a key boundary condition for controlling the forming quality of aluminium alloy ***,due to the oxidation and adhesion tendency of aluminium alloys,the tribological situations of aluminium alloy deep drawing(AADD)system is more complicated than those of traditional deep drawing of steel ***,the study of AADD friction is essential for manufacturing high-performance aluminium alloy ***,aiming to provide a valuable reference for researchers in related fields,a comprehensive review of AADD friction is provided,including friction mechanism,influencing factors,friction measurement,friction model,friction simulation,and lubrication-free friction ***,a brief conclusion and several current challenges were discussed.

关键词： aluminium alloy deep drawing(AADD) influencing factors friction measurement friction model friction control

A robust indium-organic framework with open tubular channels for efficient separation of acetylene

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第4期17卷 3139-3146页

作者： Yong-Zhi Li Gang-Ding Wang fan Xu Qing Yin danyang Zhao Jiqiu Qi Yanwei Sui Lei Hou Yao-Yu Wang School of Materials and Physics China University of Mining and TechnologyXuzhou 221116China Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education Shaanxi Key Laboratory of Physico-Inorganic ChemistryCollege of Chemistry&Materials ScienceNorthwest UniversityXi’an 710069China

Considering the tremendous applications and purification requirement of acetylene(C_(2)H_(2)),seeking appropriate adsorbents with high capacity and selectivity is a vital task and remains an enduring ***,we designed and synthesized a robust three-dimensional(3D)indium-organic framework([(Me)_(2)NH_(2)][In(L6)_(0.5)(IPA)_(0.5)]·DMA·2H_(2)O(In-L6-IPA,DMA=dimethylammonium,IPA=isopropyl alcohol))featuring two types of one-dimensional(1D)tubular *** activated In-L6-IPA displayed high loading for C_(2)H_(2)(104.4 cm^(3)·g^(-1),the second highest value among all reported indium-based metal-organic frameworks(MOFs))and simultaneously selective adsorption for C_(2)H_(2) over CO_(2),C_(2)H_(6),and ethylene(C_(2)H_(4))at 298 K under 100 *** modelling revealed that the porous wall of In-L6-IPA provides more and stronger multiple interactions for C_(2)H_(2) than CO_(2),C_(2)H_(6),and C_(2)H_(4) containing C–H···π,C–H···O,and O···π*** experiments validated the actual separation ability for various ratios of binary C_(2)H_(2)/C_(2)H_(4) and C_(2)H_(2)/CO_(2) mixtures as well as equimolar ternary C_(2)H_(2)/C_(2)H_(4)/CO_(2) and C_(2)H_(2)/C_(2)H_(4)/C_(2)H_(6) mixtures with excellent reusability.

关键词： indium-organic framework crystal structure gas adsorption acetylene(C_(2)H_(2))separation

IRE1α regulates the PTHrP-IHH feedback loop to orchestrate chondrocyte hypertrophy and cartilage mineralization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 464-478页

作者： Mengtian fan Nana Geng Xingyue Li danyang Yin Yuyou Yang Rong Jiang Cheng Chen Naibo Feng Li Liang Xiaoli Li Fengtao Luo Huabing Qi Qiaoyan Tan Yangli Xie Fengjin Guo Laboratory of Developmental Biology Department of Cell Biology and GeneticsSchool of Basic Medical ScienceChongqing Medical UniversityChongqing 400016China Laboratory of Stem Cells and Tissue Engineering School of Basic Medical ScienceChongqing Medical UniversityChongqing 400016China Department of Orthopedics The 1st Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Wound Repair and Rehabilitation Medicine State Key Laboratory of TraumaBurns and Combined InjuryTrauma CenterResearch Institute of SurgeryDaping HospitalArmy Medical UniversityChongqing 400042China

Cartilage development is controlled by the highly synergistic proliferation and differentiation of growth plate chondrocytes,in which the Indian hedgehog(IHH)and parathyroid hormone-related protein-parathyroid hormone-1 receptor(PTHrP-PTH1R)feedback loop is *** inositol-requiring enzyme 1a/X-box-binding protein-1 spliced(IRE1α/XBP1s)branch of the unfolded protein response(UPR)is essential for normal cartilage ***,the precise role of ER stress effector IRE1α,encoded by endoplasmic reticulum to nucleus signaling 1(ERN1),in skeletal development remains ***,we reported that loss of IRE1α accelerates chondrocyte hypertrophy and promotes endochondral bone ***1 acts as a negative regulator of chondrocyte proliferation and differentiation in postnatal growth *** deficiency interrupted PTHrP/PTH1R and IHH homeostasis leading to impaired chondrocyte hypertrophy and ***1s,produced by p-IRE1α-mediated splicing,binds and up-regulates PTH1R and IHH,which coordinate cartilage ***,ER stress cannot be activated normally in ERN1-deficient *** conclusion,ERN1 deficiency accelerates chondrocyte hypertrophy and cartilage mineralization by impairing the homeostasis of the IHH and PTHrP/PTH1R feedback loop and ER ***1 may have a potential role as a new target for cartilage growth and maturation.

关键词： Cartilage development ER stress ERN1 IHH PTHrP/PTH1R

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

碳材料修饰零价铝的作用机制

化学进展 2022年第5期34卷 1203-1217页

作者：杨世迎范丹阳保晓娟傅培瑶海洋环境与生态教育部重点实验室青岛266100 山东省海洋环境地质工程重点实验室青岛266100 中国海洋大学环境科学与工程学院青岛266100

零价铝(Zero-Valent Aluminum,ZVAl)因具有极低的氧化还原电位,使其成为良好的电子供体,是环境工程污染物降解领域中极具潜势的零价金属。然而,由于ZVAl的强还原活性,其表面易形成致密的氧化薄膜、破膜后易再次钝化和电子的利用率低等缺... 详细信息

零价铝(Zero-Valent Aluminum,ZVAl)因具有极低的氧化还原电位,使其成为良好的电子供体,是环境工程污染物降解领域中极具潜势的零价金属。然而,由于ZVAl的强还原活性,其表面易形成致密的氧化薄膜、破膜后易再次钝化和电子的利用率低等缺点,制约了其与污染物的反应。研究表明,碳材料在修饰ZVAl时,不仅可以引发电偶和晶间腐蚀、强化传质过程、加速电子转移,提高ZVAl的反应效率;还能赋予材料优异的机械强度,克服ZVAl自身的弊端,阻滞氧气和腐蚀介质的侵蚀,维持材料的长效性;此外,碳材料的亲疏水性质、带电荷和表面官能团的可调性提高了材料对污染物的特异性吸附,高催化活性使底物实现定向转化,提高了ZVAl体系的电子利用效率。鉴于此,本文系统总结了活性炭、石墨、碳纳米管和石墨烯等碳材料在不同修饰方法下对ZVAl的作用机制、产生的功能效用,探讨了修饰参数(碳材料的种类和比例、过程控制剂的种类、热处理的温度和时间、ZVAl的几何形态等)对复合材料的影响规律,并就精确控制参数、深入研究机理,实现功能化复合材料的定向制备以拓宽其应用价值进行了展望。以期通过不同学科相关领域的深入了解,促进铝碳复合材料在环境污染治理领域的进一步发展。

关键词：碳材料零价铝反应机制反应活性稳定性选择性

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

骨改建过程中大麻素受体的表达及作用

中国组织工程研究 2022年第2期26卷 283-288页

作者：范丹阳付润泽米佳静刘春艳河北医科大学河北省石家庄市050017 河北医科大学口腔医(学)院正畸科河北省口腔医学重点实验室河北省口腔疾病临床医学研究中心河北省石家庄市050017

背景:大麻素受体如何调节成骨细胞和破骨细胞,维持正常的骨改建过程,在骨骼正常发育、骨量维持以及骨质疏松和牙周炎的治疗等方面具有重要意义。目的:综述大麻素受体与骨改建的关系及相关影响因素,为骨质疏松、牙周炎治疗以及其在临床... 详细信息

背景:大麻素受体如何调节成骨细胞和破骨细胞,维持正常的骨改建过程,在骨骼正常发育、骨量维持以及骨质疏松和牙周炎的治疗等方面具有重要意义。目的:综述大麻素受体与骨改建的关系及相关影响因素,为骨质疏松、牙周炎治疗以及其在临床其他领域的应用提供思路。方法:检索Pub Med、FMRS、万方数据库、CNKI中国期刊全文数据库2001年7月至2020年7月收录的相关文献。英文检索词为"endocannabinoid systems,the endocannabinoid receptors,osteoblasts,osteoclasts,bone mass,bone remodeling,oral health,osteoporosis,periodontitis",中文检索词为"内源性大麻素系统,大麻素受体,成骨细胞,破骨细胞,骨量,骨改建,口腔健康,骨质疏松症,牙周炎",最终纳入77篇文献进行归纳总结。结果与结论:(1)骨改建依赖于成骨细胞和破骨细胞的相互作用,骨吸收与骨形成之间的失衡会影响骨改建过程,导致骨质疏松、牙周炎等骨骼炎症性疾病;(2)内源性大麻素系统包含多种受体,均属于G蛋白偶联超家族成员;两种主要的受体(大麻素Ⅰ型和大麻素Ⅱ型)在成骨细胞、破骨细胞以及骨髓间充质干细胞等骨相关细胞中均存在表达;(3)在天然配体或人工合成激动剂的作用下,大麻素受体可通过不同的代谢通路在体内外产生特定的生理效应,从而调节骨细胞的生成和分化,最终影响骨量和骨代谢;(4)进一步研究其对骨形成和骨丢失的机制,为骨相关疾病的临床工作提供新的治疗思路成为目前研究的重点。

关键词：大麻素受体成骨细胞破骨细胞骨髓间充质干细胞骨量骨改建骨质疏松症牙周炎

基于PC集群多通道视景仿真系统的设计与实现

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

计算机工程与应用 2015年第18期51卷 204-208页

作者：范丹阳贠卫国西安建筑科技大学信息与控制工程学院西安710055

使用PC集群实现了多通道视景仿真,在给用户带来较大的视野和强烈沉浸感的同时可以得到较高的性价比。针对基于PC集群多通道视景仿真系统的系统框架进行了研究,使用OSG三维图形渲染引擎,提出了一种基于投影变换的分屏方法,并应用于基于P... 详细信息

使用PC集群实现了多通道视景仿真,在给用户带来较大的视野和强烈沉浸感的同时可以得到较高的性价比。针对基于PC集群多通道视景仿真系统的系统框架进行了研究,使用OSG三维图形渲染引擎,提出了一种基于投影变换的分屏方法,并应用于基于PC集群的多通道视景仿真系统。实验结果表明与旋转视锥体方法相比该方法改善了在通道交界处产生"偏折"的现象,能够灵活、简便地进行分屏,方便地达到扩大视野或获得更大的显示尺寸的目的,保持了视景仿真中多通道视景和交互的同步并保持了画面的流畅。

关键词：基于工业标准OpenGL跨平台的三维开源场景图形系统应用程序开发接口多通道视景仿真分屏技术计算机集群

Application of three-dimensional speckle tracking technique in measuring left ventricular myocardial function in patients with diabetes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第4期15卷 783-792页

作者： Zheng Li Ying Qian Chun-Yun fan Yong Huang Department of Ultrasound The People’s Hospital of DanyangDanyang Hospital of Nantong UniversityDanyang 212300Jiangsu ProvinceChina Department of Endocrinology The People’s Hospital of DanyangDanyang Hospital of Nantong UniversityDanyang 212300Jiangsu ProvinceChina

BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is *** To explore the use of the three-dimensional speckle tracking technique(3D-STI)for measuring LVSF in DM patients via *** The electronic databases were retrieved from the initial accessible time to 29 April *** current study involved 9 studies,including 970 *** carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by *** Night articles including 970 subjects were *** significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group(P>0.05),while differences in global longitudinal strain,global circumferential strain,global radial strain,and global area strain were markedly different between the controls and DM patients(all P<0.05).CONCLUSION The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.

关键词： Diabetes mellitus Left ventricular systolic dysfunction Three-dimensional speckle tracking echocardiography Meta analysis

全媒体传播视域下的"网络邪教"治理策略研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

科学与无神论 2024年第1期 113-122页

作者：薛鹏范宝祥刘丹阳北京联合大学北京膜拜团体与宗教文化研究中心

邪教产生危害的本质在于膜拜性蛊惑虚假信息对人的危害.全媒体时代下邪教借助互联网媒介进行信息传播的程度空前加深,"网络邪教"现象愈演愈烈."网络邪教"的传播与流行病学的病毒传播状态模型极为相似.我们应以驱动不同传播状态的个体最... 详细信息

邪教产生危害的本质在于膜拜性蛊惑虚假信息对人的危害.全媒体时代下邪教借助互联网媒介进行信息传播的程度空前加深,"网络邪教"现象愈演愈烈."网络邪教"的传播与流行病学的病毒传播状态模型极为相似.我们应以驱动不同传播状态的个体最终进入免疫状态为要.为达成这一目标,"网络邪教"治理可划分为两条主线:一是面向广大受众的教育引导,依赖于传播内容的设计以及与内容相适配的传播渠道和形式的选择;二是面向"网络邪教"成员的帮扶,构建围绕帮扶个体的移动社群环境,创设适宜传播场景,形成现行的针对邪教成员的教育转化与线上帮扶场景的融合互补.

关键词：网络邪教传播策略移动社群

Erratum to: A robust indium-organic framework with open tubular channels for efficient separation of acetylene

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第4期17卷 3425-3425页

Erratum to Nano Research,2024,17(4):3139–3146 https://***/10.1007/s12274-023-6061-8 In the first page of the original version of this paper,the corresponding authors should be“Yanwei Sui”and“Lei Hou”,instead of“Lei Hou”and“Yao-Yu Wang”.And“Address correspondence to:Lei Hou,lhou2009@***;Yao-Yu Wang,wyds123456@***”should be corrected to“Address correspondence to:Lei Hou,lhou2009@***;Yanwei Sui,wyds123456@***”.

关键词： separation correspondence outlook