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CRH Neurons in the Laterodorsal Tegmentum Mediate Acute Stress-induced Anxiety

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Neuroscience Bulletin 2021年第7期37卷 999-1004页

作者： Wenqi Tang danqing zhou Siyu Wang Sijia Hao Xiaomeng Wang Mohamed Helmy Junming Zhu Hao Wang Department of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital Key Laboratory for Biomedical Engineering of the Ministry of EducationZhejiang University School of MedicineHangzhou 310058China NHC and CAMS Key Laboratory of Medical Neurobiology MOE Frontier Science Center for Brain Research and Brain Machine IntegrationSchool of Brain Science and Brain MedicineZhejiang UniversityHangzhou 310058China Department of Neurosurgery Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310058China Children’s Hospital Zhejiang University School of MedicineHangzhou 310052China

Dear Editor,Acute stress-induced anxiety is pervasive in both animals and *** natural stress response effectively helps animals to maintain arousal,flee from danger,or simply stay alert to their *** the other hand,excessive anxiety is strongly associated with many severe psychiatric disorders such as depression,phobia,and posttraumatic stress disorder(PTSD).Although the probability of an individual suffering clinical anxiety reaches an average of 28%during their lifetime,the underlying neural mechanisms of anxiety remain poorly understood.

关键词： Acute maintain lifetime

Preparation of graphene on SiC by laser-accelerated pulsed ion beams

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Chinese Physics B 2021年第11期30卷 455-460页

作者： danqing zhou Dongyu Li Yuhan Chen Minjian Wu Tong Yang Hao Cheng Yuze Li Yi Chen Yue Li Yixing Geng Yanying Zhao Chen Lin Xueqing Yan Ziqiang Zhao State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Beijing Laser Acceleration Innovation Center HuairouBeijing 101400China Institute of Guangdong Laser Plasma Technology Guangzhou 510540China

Laser-accelerated ion beams(LIBs) have been increasingly applied in the field of material irradiation in recent years due to the unique properties of ultra-short beam duration, extremely high beam current, etc. Here we explore an application of using laser-accelerated ion beams to prepare graphene. The pulsed LIBs produced a great instantaneous beam current and thermal effect on the SiC samples with a shooting frequency of 1 Hz. In the experiment, we controlled the deposition dose by adjusting the number of shootings and the irradiating current by adjusting the distance between the sample and the ion source. During annealing at 1100℃, we found that the 190 shots ion beams allowed more carbon atoms to self-assemble into graphene than the 10 shots case. By comparing with the controlled experiment based on ion beams from a traditional ion accelerator, we found that the laser-accelerated ion beams could cause greater damage in a very short time. Significant thermal effect was induced when the irradiation distance was reduced to less than 1 cm, which could make partial SiC self-annealing to prepare graphene dots directly. The special effects of LIBs indicate their vital role to change the structure of the irradiation sample.

关键词： laser ion acceleration graphene self-annealing

基于平衡计分卡的公立医院临床专科中心化建设评价模型构建

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中国医院 2025年第1期29卷 46-49页

作者：周丹青刘正强王萍殷钧王聪健包桂丽宋花花刘蕊同济大学附属上海市第十人民医院上海市200072 复旦大学附属中山医院吴淞医院上海市200940

目的:建立公立医院临床专科中心化建设评价模型。方法:基于平衡计分卡,从中心结构、临床发展能力、财务运营、技术创新和临床转化能力等维度建立公立医院临床专科中心化建设评价框架,通过德尔菲法构建评价指标体系,结合层次分析法来确... 详细信息

目的:建立公立医院临床专科中心化建设评价模型。方法:基于平衡计分卡,从中心结构、临床发展能力、财务运营、技术创新和临床转化能力等维度建立公立医院临床专科中心化建设评价框架,通过德尔菲法构建评价指标体系,结合层次分析法来确定权重。结果:构建了包含5个一级指标、11个二级指标,28个三级指标的公立医院专科中心化建设评价模型。结论:本研究构建的公立医院专科中心化建设评价模型具有一定的推广性,在实际应用中,医院可根据实际发展情况重新确定权重系数从而形成适宜医院发展的临床专科中心化建设评价模型。

关键词：专科中心化评价指标体系德尔菲法

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Observations on the morphology of embryonic and larval development in Styela canopus Savigny

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Acta Oceanologica Sinica 2003年第4期22卷 621-628页

作者： Huang Ying1, Ke Caihuan 1, Feng danqing1, zhou Shiqiang1, Li Fuxue1 1. Department of Oceanography, Institute of Subtropic Oceanography, Key Laboratory for Marine Environmental Science of the Ministry of Education, Xiamen University, Xiamen 361005, China Department of Oceanography Institute of Subtropic Oceanography Key Lab. for Marine Environ. Science Xiamen 361005 China

The morphological characters on different developmental phases of embryo and larva and the schedule of the whole early developmental process in Styela canopus were observed and described. The types of reproduction and early development as well as the morphology, of egg and larva in different ascidian species were compared. Styela canopus is oviparous. Its egg, 230.4 similar to 336.0 mum in diameter, is equipped with extraembryonic cell layers measured 43.2 similar to 63.0 mum thick. The early development of Styela canopus is typical urodele development, including fertilization, cleavage, gastrulation, tadpole in membrane, tadpole, initiating metamorphosis and juvenile. The tadpole of Styela canopus, with a length of 0.6 similar to 0. 9 mm, consists of trunk and tail. There are obvious notochord, ocellus and adhesive papillae in the tadpole. Under the water temperature of (25 +/- 0-5) degreesC and the salinity of 27.0, the larva was hatched after 9.5 similar to 11.0 h since the fertilization.

关键词： Styela canopus embryo larvae tadpole larvae ascidian

碳离子注入辅助在6H-SiC表面制备石墨烯

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北京大学学报（自然科学版） 2021年第3期57卷 407-413页

作者：陈钰焓赵子强赵云彪陈艺周丹晴北京大学物理学院核物理与核技术国家重点实验室北京100871

为了寻找一种更便捷、更经济的在半导体SiC基底上直接生长石墨烯的方法,将5 keV C离子注入商用6H-SiC(0001)单晶,通过拉曼光谱、扫描电子显微镜(SEM)和原子力显微镜(AFM)表征研究石墨烯质量和生长过程。实验中还研究了不同降温速率以及... 详细信息

为了寻找一种更便捷、更经济的在半导体SiC基底上直接生长石墨烯的方法,将5 keV C离子注入商用6H-SiC(0001)单晶,通过拉曼光谱、扫描电子显微镜(SEM)和原子力显微镜(AFM)表征研究石墨烯质量和生长过程。实验中还研究了不同降温速率以及石墨舟的封闭环境对石墨烯生长的影响,并基于Si原子的蒸发提出一个可能的生长机制。结果表明,封闭的石墨舟可以有效地限制Si原子的蒸发,降温速率会影响C原子的析出和表面自组装,合适的降温速率可以使注入的C原子在表面析出,从而直接在6H-SiC表面自组装形成双层至多层石墨烯。该方法能够将制备温度降至1100℃,制备过程不需要氢刻蚀、超高真空或特殊气氛条件,过程简单,降低了对仪器设备的要求。

关键词：碳离子注入石墨烯 SiC 石墨舟

叶海运用“经纬辨证”理论治疗股骨头无菌性坏死经验

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浙江中医杂志 2019年第11期54卷 781-783页

作者：周丹庆浙江省宁波市鄞州区中西医结合医院

叶海主任中医师,系第二批全国老中医药专家学术经验继承工作指导老师,从事中医骨伤科临床诊疗工作逾五十载,博览群书,学验俱丰,在对骨伤疾病的临证诊治方面有独道的见解。叶师在结合前人相关经验基础上,提出了“经纬辨证”理论,为骨伤... 详细信息

叶海主任中医师,系第二批全国老中医药专家学术经验继承工作指导老师,从事中医骨伤科临床诊疗工作逾五十载,博览群书,学验俱丰,在对骨伤疾病的临证诊治方面有独道的见解。叶师在结合前人相关经验基础上,提出了“经纬辨证”理论,为骨伤疾病的诊疗提供了捷径。笔者有幸跟随叶师临证学习,获益匪浅,兹将叶师运用“经纬辨证”理论治疗股骨头无菌性坏死的经验总结如下,供同道参考。

关键词：股骨头无菌性坏死经纬辨证叶海

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会展危机管理中的RCRR模型分析

经济师 2009年第5期 10-12页

作者：周丹青华东师范大学商学院上海200241

会展作为一种特殊的重大经贸活动,人流、物流、信息流高度集中,是一个对危机较为敏感的行业。文章从会展危机的基本概念和特点入手,将会展危机分为不可预知的自然危机和可预知的人为危机两大类,指出会展危机管理的必要性,最后构建RCRR模... 详细信息

会展作为一种特殊的重大经贸活动,人流、物流、信息流高度集中,是一个对危机较为敏感的行业。文章从会展危机的基本概念和特点入手,将会展危机分为不可预知的自然危机和可预知的人为危机两大类,指出会展危机管理的必要性,最后构建RCRR模式,阐述了其在会展危机管理中的应用。

关键词：会展危机危机管理 RCRR

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叶海从督脉论治强直性脊柱炎经验介绍

新中医 2020年第12期52卷 223-225页

作者：周丹庆叶海(指导) 宁波市鄞州区中西医结合医院浙江宁波315040 宁波市中医院浙江宁波315040

叶海(1940-),男,主任中医师,第二批全国老中医药专家学术经验继承工作指导老师,享受国务院特殊津贴。叶海教授从事骨科临床和研究工作逾五十载,致力于骨科疾病中医机理和治疗学研究,尤其对强直性脊柱炎的病因病机及辨证论治等积累了丰... 详细信息

叶海(1940-),男,主任中医师,第二批全国老中医药专家学术经验继承工作指导老师,享受国务院特殊津贴。叶海教授从事骨科临床和研究工作逾五十载,致力于骨科疾病中医机理和治疗学研究,尤其对强直性脊柱炎的病因病机及辨证论治等积累了丰富的经验,倡导从督脉论治强直性脊柱炎。强直性脊柱炎是一种原因不明的以中轴关节的慢性炎症为主要表现的全身免疫性疾病,可伴有周围关节炎、附着点炎以及炎性肠病、葡萄膜炎和银屑病等关节外表现[1]。

关键词：强直性脊柱炎督脉宣通督阳补督扶阳叶海名医经验

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叶海治疗痛风性关节炎经验介绍

新中医 2020年第1期52卷 188-189页

作者：周丹庆叶海(指导) 浙江中医药大学浙江杭州310053 宁波市鄞州区中西医结合医院浙江宁波315040 宁波市中医院浙江宁波315040

痛风性关节炎是一种非特异性炎症反应性疾病,具有易复发、难治愈的特点,它越来越多地影响着患者的生活与工作,严重危害健康。叶海主任中医师对治疗痛风性关节炎积累了丰富的经验,疗效显著。笔者有幸跟随叶主任学习,兹将其诊治痛风性关... 详细信息

痛风性关节炎是一种非特异性炎症反应性疾病,具有易复发、难治愈的特点,它越来越多地影响着患者的生活与工作,严重危害健康。叶海主任中医师对治疗痛风性关节炎积累了丰富的经验,疗效显著。笔者有幸跟随叶主任学习,兹将其诊治痛风性关节炎的经验介绍如下。

关键词：痛风性关节炎脾肾亏虚瘀浊凝滞叶海