检索结果-南通市图书馆

Gastric Bypass with Long Pouch and Transit Bipartition for Endoscopic Access to the Remaining Stomach

Surgical Science 2022年第8期13卷 353-366页

作者： Paulo Reis Esselin de Melo Marcella Giovana Gava-Brandolis Thonya Cruz Braga danilo Fossalussa Minari Ricardo Augusto Martins Bueno da Costa Jose Geraldo Moraes Sampaio Neto Louise Flores Silva José Humberto Cardoso Resende Hospital Estadual Alberto Rassi Surgical Skills Coordinator Goi&#226nia Brazil UNIFAN Research Coordinator Aparecida de Goi&#226nia Brazil

Introduction: obesity has a complex and multifactorial etiology, difficult treatment and increasing incidence rates in recent decades. The treatment involves clinical and pharmacological approaches and, in case of lack of results, surgical interventions. Roux-en-Y gastric bypass (RYGB) is one of these surgical interventions in which the stomach is divided, creating a small pouch, and the remaining portion of the stomach become excluded and left without endoscopic access. Objective: to evaluate the results of modified RYGB with long pouch and endoscopic access to the remaining stomach. Materials and Methods: prospective clinical trial with sample selected among patients seen at the Alberto Rassi General State Hospital of Goiânia (HGG) and indicated for bariatric and metabolic surgery confirmed by the medical and multidisciplinary team. The study was conducted from January 2020 to August 2021. Clinical history and laboratory test results of the selected patients were collected through consultations with the medical and multidisciplinary team. Results: twelve participants were included in the study. Of these, 11 (91.7%) were women and the mean age was 46.3 years. The weight before surgery was 112.17 kg (92.00 - 150.00) and the Body Mass Index (BMI) was 44.89 (35.06 - 74.39). After 18 months of surgery, the mean weight was 80.77 kg (±11.92) and the mean BMI was 29.46 (±11.00), showing a significant reduction in both (p = 0.003 and p = 0.002, respectively). All patients underwent endoscopic evaluation of the pouch, remaining stomach and duodenum at 12 months postoperatively. The mean percentage of lost excess weight loss was 68.21%. Conclusion: We conclude that the proposed changes in RYGB (GBLP + GIB – Roux-en-Y gastric bypass with long pouch and gastrointestinal bipartition) did not compromise weight loss or control of type 2 diabetes and other comorbidities and proved to be a safe and effective alternative without gastroduodenal exclusion, enabling a better postop

关键词： Obesity Bariatric Surgery Metabolic Surgery Roux-En-Y Gastric Bypass

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Two mitochondrial phosphatases,PP2c63 and Sal2,are required for posttranslational regulation of the TCA cycle in Arabidopsis

引用

Molecular Plant 2021年第7期14卷 1104-1118页

作者： Youjun Zhang Jonas Giese Sandra M.Kerbler Beata Siemiatkowska Leonardo Perez de Souza Jessica Alpers David Barbosa Medeiros Dirk K.Hincha danilo M.Daloso Mark Stitt Iris Finkemeier Alisdair R.Fernie Max-Planck-lnstitut fur Molekulare Pflanzenphysiologie Am Muhlenberg 114476 Potsdam-GolmGermany Center of Plant Systems Biology and Biotechnology 4000 PlovdivBulgaria lnstitute of Plant Biology and Biotechnology University of MuensterSchlossplatz 748149 MuensterGermany Departamento de Bioquimica e Biologia Molecular Universidade Federal do CearaFortalezaCearaBrasil

Protein phosphorylation is a well-established post-translational mechanism that regulates protein functions and metabolic *** is known that several plant mitochondrial proteins are phosphorylated in a reversible ***,the identities of the protein kinases/phosphatases involved in this mech-anism and their roles in the regulation of the tricarboxylic acid(TCA)cycle remain *** this study,we isolated and characterized plants lacking two mitochondrially targeted phosphatases(Sal2 and PP2c63)along with pyruvate dehydrogenase kinase(PDK),Protein-protein interaction analysis,quantitative phos-phoproteomics,and enzymatic analyses revealed that PDK specifically regulates pyruvate dehydrogenase complex(PDC),while PP2c63 nonspecifically regulates *** recombinant PP2c63 and Sal2 proteins were added to mitochondria isolated from mutant plants,protein-protein interaction and enzymatic analyses showed that PP2c63 directly phosphorylates and modulates the activity of PDC,while Sal2 only indirectly affects TCA cycle *** of steady-state metabolite levels and fluxes in the mutant lines further revealed that these phosphatases regulate flux through the TCA cycle,and that altered metabolism in the sa/2 pp2c63 double mutant compromises plant *** results are discussed in the context of current models of the control of respiration in plants.

关键词： TCA cycle pyruvate dehydrogenase phosphorylation mitochondrial protein phosphatase TCA cycle enzymes phosphorylation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison between Different ESI Methods on Refractory Epilepsy Patients Shows a High Sensitivity for Bayesian Model Averaging

引用

Journal of Biomedical Science and Engineering 2014年第9期7卷 662-674页

作者： danilo Maziero Agustin Lage Castellanos Carlos Ernesto Garrido Salmon Tonicarlo Rodrigues Velasco Cuba Neuroscience Center Havana Cuba Department of Physics FFLCRP University of S&atilde o Paulo Ribeir&atilde o Preto Brazil Epilepsy Surgery Center Department of Neuroscience Faculty of Medicine University of S&atilde o Paulo Ribeir&atilde o Preto Brazil

Electrical Source Imaging (ESI) is a non-invasive technique of reconstructing brain activities using EEG data. This technique has been applied to evaluate epilepsy patients being evaluated for epilepsy surgery, showing encouraging results for mapping interictal epileptiform discharges (IED). However, ESI is underused in planning epilepsy surgery. This is basically due to the wide availability of methods for solving the electromagnetism inverse problem (e-IP) associated to few studies using EEG setups similar to those most commonly used in clinical setting. In this study, we applied six different methods of solving the e-IP based on IEDs of 20 focal epilepsy patients that presented abnormalities in their MRI. We compared the ESI maps obtained by each method with the location of the abnormality, calculating the Euclidian distances from the center of the lesion to the closest border of the method solution (CL-BM) and also to the solution’s maxima (CL-MM). We also applied a score system in order to allow us to evaluate the sensitivity of each method for temporal and extra temporal patients. In our patients, the Bayesian Model Averaging method had a sensitivity of 86% and the shortest CL-MM. This method also had more restricted solutions that were more representative of epileptogenic activities than those obtained by the other methods.

关键词： EEG Epilepsy Electrical Source Imaging Bayesian Model Averaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between the Adherence to AHA Step 1 Nutrition Criteria and the Cardiometabolic Outcome in the General Population a Two Year Follow-Up Study

引用

Food and Nutrition Sciences 2012年第2期3卷 274-280页

作者： Laura Redaelli Katia Garlaschelli Liliana Grigore Giuseppe danilo Norata Alberico Luigi Catapano Center for the Study of Atherosclerosis SISA Sez Reg Lomb Bassini Hospital Cinisello Balsamo Italy Center for the Study of Atherosclerosis SISA Sez Reg Lomb Bassini Hospital Cinisello Balsamo Italy 2Department of Phar- macological Sciences Università degli Studi di Milano Milan Italy Department of Phar- macological Sciences Università degli Studi di Milano Milan Italy I.R.C.C.S. Multimedica Milan Italy Department of Phar- macological Sciences Università degli Studi di Milano Milan Italy I.R.C.C.S. Multimedica Milan Italy.

Introduction: The National Cholesterol Education Program and the American Heart Association considered a dietary therapy as a primary approach to prevent and treat hyperlipemia and hypertension. Mediterranean diet has been promoted as a model of healthy eating and widely recognized for favorable effects on lipid profile. Objective: We investigated whether the adherence to dietary recommendations have any significant benefit on cardiovascular risk factors. A cohort of 2141 of subjects attending our center was recruited by collaborating General Practitioners who participate in the PLIC Study. Methods: Participants completed a week quantitative food questionnaire, which was analized on a subgroup of 338 subjects at enrolment (V1) and after two years of follow up (V2). Daily energy intake in Kcal, lipid, protein, carbohydrates in percentage of total energy, monounsatured (MUFA), saturated (SFA), polyunsaturated fatty acids (PUFA) in g/die, cholesterol in mg/die was calculated from the food questionnaires. Cardiovascular risk (CVR) was estimated according Framingham algorithm. Results: Subjects which adhered to AHA step 1 diet showed a significantly lower total cholesterol, 213.88 ± 43.00 vs 220.19 ± 39.3 mg/dL, LDL-cholesterol, 139.80 ± 76.36 vs 142.75 ± 35.60 mg/dL (p < 0.01 for both) as compared to subjects with an impaired dietary pattern while no differences were observed for HDL cholesterol. Conclusions: Changes in dietary profiles are associated with an improved lipid profile and therefore remain one of the more favorable nutritional models in the primary prevention of cardiovascular disease.

关键词： AHA Step 1 MUFA PUFA Cholesterol

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Extracellular RNAs as potential biomarkers for cancer

引用

Journal of Cancer Metastasis and Treatment 2020年第1期6卷 364-381页

作者： Christine Happel Aniruddha Ganguly danilo A.Tagle National Center for Advancing Translational Sciences National Institutes of HealthBethesdaMD 20892USA Cancer Diagnosis Program Division of Cancer Treatment and DiagnosisNational Cancer Institute at the National Institutes of HealthBethesdaMD 20892USA

The discovery that all cells secrete extracellular vesicles(EVs)to shuttle proteins and nucleic acids to recipient cells suggested they play an important role in intercellular *** are widely distributed in many body fluids,including blood,cerebrospinal fluid,urine and *** are nano-sized EVs of endosomal origin that regulate many pathophysiological processes including immune responses,inflammation,tumour growth,and *** individuals release exosomes with a cargo of different RNA,DNA,and protein contents into the circulation,which can be measured non-invasively as biomarkers of healthy and diseased ***-derived exosomes carry a unique set of DNA,RNA,protein and lipid reflecting the stage of tumour progression,and may serve as diagnostic and prognostic biomarkers for various ***,many gaps in knowledge and technical challenges in EVs and extracellular RNA(exRNA)biology,such as mechanisms of EV biogenesis and uptake,exRNA cargo selection,and exRNA detection *** NIH Common Fund-supported exRNA Communication Consortium was launched in 2013 to address major scientific challenges in this *** review focuses on scientific highlights in biomarker discovery of exosome-based exRNA in cancer and its possible clinical application as cancer biomarkers.

关键词： Extracellular vesicles exosomes extracellular RNA cancer biomarker liquid biopsy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

2015家纺新风向

引用

缤纷 2015年第4期 104-105页

作者： danilo Beltrame

＂参加商展总是一个不寻常的经历,而连续参加三场商展则更是一种巨大的挑战。连续多年来,每年的这个时候,我都会放下手头的工作,相继参加了科隆国际家具展、德国法兰克福国际家用纺织品展以及巴黎家居装饰博览会。＂——danilo Beltram... 详细信息

＂参加商展总是一个不寻常的经历,而连续参加三场商展则更是一种巨大的挑战。连续多年来,每年的这个时候,我都会放下手头的工作,相继参加了科隆国际家具展、德国法兰克福国际家用纺织品展以及巴黎家居装饰博览会。＂——danilo Beltrame根据主办方的介绍,本次法兰克福国际家用纺织品展吸引了2759家厂商参与,而观展者数目达68000人之多。

关键词：家用纺织品国际家具展德国法兰克福家居装饰纤维素纤维用品市场航空航天局麻制品流行趋势消费趋势

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

打破常规、突破界限 2015年新加坡设计周

引用

缤纷 2015年第4期 100-103页

作者： danilo Beltrame

融合了商展、艺术展、陈列展、研讨会等的特点,今年＂新加坡设计周＂对＂狮城＂设计艺术来说,依然是一份极佳的馈赠。新加坡设计周第一次大放异彩是在去年,而今年,由于设计周承接了60场以上的活动,所以对于设计迷们来说,它可以称得上是... 详细信息

融合了商展、艺术展、陈列展、研讨会等的特点,今年＂新加坡设计周＂对＂狮城＂设计艺术来说,依然是一份极佳的馈赠。新加坡设计周第一次大放异彩是在去年,而今年,由于设计周承接了60场以上的活动,所以对于设计迷们来说,它可以称得上是一次饕餮盛宴。

关键词：国际家具饕餮盛宴打破常规编织图案建筑工程师 Alvin 现代思想城市环境花器了真

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

科隆国际家具展

引用

缤纷 2015年第4期 106-107页

作者： danilo Beltrame

科隆厨房生活展作为久负盛名的国际厨业展会,今年共吸引了来自138个国家的14.6万人参与,根据主办方的统计数据,其中10.2万参展人员从事国内和国际贸易。本次科隆厨房生活展致力于一个问题：＂未来的厨房长什么样？＂以及无法避免的,与... 详细信息

科隆厨房生活展作为久负盛名的国际厨业展会,今年共吸引了来自138个国家的14.6万人参与,根据主办方的统计数据,其中10.2万参展人员从事国内和国际贸易。本次科隆厨房生活展致力于一个问题：＂未来的厨房长什么样？＂以及无法避免的,与之相关的另一个问题＂厨房的未来究竟在哪？＂

关键词：国际家具展厨房设计参展人员统计数据一个问题开放式厨房社交场所家庭人员个性化定制上海弄堂

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A decade of WH02010:total sperm number temporal trend and role of lifestyle factors

引用

Asian Journal of Andrology 2023年第5期25卷 572-577页

作者： Francesco Cargnelutti Francesco Pallotti Tania Carlini Fabiana Faja Anna Rita Vestri danilo Alunni Fegatelli Andrea Lenzi Francesco Lombardo Donatella Paoli Laboratory of Seminology-Sperm Bank"Loredana Gandini" Department of Experimental MedicineSapienza University of RomeViale del Pliclinico 155Roma 00161Italy Department of Public Health and Infectious Disease Sapienza University of RomeViale del Polclinico 155Roma 00161Italy

After a huge decline in sperm concentration between 1938 and 1991 was reported,many researchers investigated the possibility of a worsening of human sperm *** massive efforts,published evidence is still ***,the role of lifestyle factors on semen parameters is *** conducted a monocentric Italian study to evaluate the total sperm number trend over the last 10 years(from 2010 to 2019).Additionally,we evaluated the association between lifestyle factors and total sperm number in order to identify possible damaging *** performed a retrospective study analyzing subjects aged 18-55 years who had their semen analyzed between 2010 and 2019.A total of 3329 subjects were included:1655 subjects referred to our department(Department of Experimental Medicine,Sapienza University of Rome,Roma,Italy)for idiopathic infertility and 1674 subjects referred for preconceptional or andrological screening with no confirmed andrological *** samples were examined according to World Health Organization(WHO)2010 criteria by two seminologists with the same training and the same *** statistical evaluations,only total sperm number(×10^(6)per ejaculate)was taken into *** detected no significant changes in mean total sperm number during the last decade,in either the entire population or the two subgroups(infertile group and control group).In a multivariate analysis total sperm number was significantly associated with the history of infertility,body mass index(BMI)and cigarette *** results suggest that infertile men are"vulnerable"subjects,particularly susceptible to several negative factors,many of which still remain *** study highlights the need for studies addressing men's lifestyle in order to find and reduce deleterious agents.

关键词： aging male infertility obesity smoking sperm decline

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures

引用

Bioactive Materials 2022年第10期7卷 173-186页

作者： Mauricio Gonçalves da Costa Sousa Gabriela Conceiçao de Almeida danilo Cesar Martins Mota Rosiane Andrade da Costa Simoni Campos Dias Samuel Nunes Limberger Frank Ko Li Ting Lin Evan FHaney Hashem Etayash Beverlie Baquir Michael J.Trimble Ya Shen Zheng Su Markus Haapasalo Daniel Pletzer Letícia Chaves de Souza Glaucia Schuindt Teixeira Renato M.Silva Robert E.W.Hancock Octavio Luiz Franco Taia Maria Berto Rezende Post-Graduation Program in Genomic Sciences and Biotechnology Catholic University of BrasíliaBrasíliaBrazil Dentistry Course Catholic University of BrasíliaBrasíliaBrazil Post-Graduation Program in Health Sciences University of BrasíliaBrazil LIMA Chemistry InstituteUniversity of Brasília-UNBBrasíliaBrazil Animal Biology Department Campus Darcy RibeiroUniversidade de BrasíliaBrazil Department of Materials Engineering Faculty of Applied ScienceUniversity of British ColumbiaVancouverCanada Department of Microbiology and Immunology University of British ColumbiaVancouverBCCanada Department of Oral Biological and Medical Sciences Faculty of DentistryUniversity of British ColumbiaVancouverCanada Department of Microbiology and Immunology University of OtagoDunedinNew Zealand Department of Endodontics School of DentistryUniversity of Texas Health Science Center at HoustonHoustonUSA Department of Prosthesis Faculty of DentistryRio de Janeiro State UniversityRio de JaneiroBrazil Post-Graduation Program in Biotechnology Catholic University Dom BoscoCampo GrandeMato Grosso do SulBrazil

Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for ***,different scaffolds were tested for use during the pulp revascularization process,including poly(vinyl alcohol)-PVA hydrogels or resins,collagen hydrogels and poly(vinyl alcohol)PVA/Chitosan(PVA/CS)*** on time to degradation(21 days),nanofibers were chosen to be incorporated with ciprofloxacin and IDR-1002(each at 50 mg/g).Nanofibers containing ciprofloxacin and IDR-1002 had anti-biofilm activity against Enterococcus faecalis,Staphylococcus aureus and a multispecies oral biofilm,besides anti-inflammatory *** in vivo subcutaneous tissue response to tooth fragments filled with nanofibers demonstrated a pulp-like tissue formation,when compared to empty teeth ***,we designed a strong antimicrobial,immunomodulatory and regenerative candidate for pulp revascularization and regeneration procedures.

关键词： Regenerative endodontics Scaffolds Nanofibers Host defense peptides Ciprofloxacin IDR-1002

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：