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Exploring overweight and obesity beyond body mass index:A body composition analysis in people with and without patellofemoral pain

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Journal of Sport and Health Science 2023年第5期12卷 630-638,F0003页

作者： Amanda Schenatto Ferreira Benjamin F Mentiplay Bianca Taborda Marcella Ferraz Pazzinatto Fabio Mıcolis de Azevedo danilo de oliveira silva department of Physiotherapy School of Science and TechnologySao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil La Trobe Sport and Exercise Medicine Research Centre School of Allied HealthHuman Services and SportLa Trobe UniversityMelbourneVIC 3086Australia

Background:We compared body mass index(BMI),body fat,and skeletal muscle mass between(1) a mixed-sex nonathletic cohort of people with patellofemoral pain(PFP) and pain-free people,and(2) a nonathletic cohort of people with PFP and pain-free people subgrouped by sex(i.e.,men and women with PFP ***-free men and women).Methods:This cross-sectional study included 114 people with PFP(71 women,43 men) and 54 pain-free controls(32 women,22 men).All participants attended a single testing session to assess body composition measures,which included BMI,percentage of body fat(%BFBioimpedance),and skeletal muscle mass(both assessed by bioelectrical impedance analysis),and percentage of body fat(%BFskinfoid)(assessed by skinfold caliper analysis).A one-way univariate analysis of covariance(age and physical activity levels as covariates) was used to compare body composition measures between groups(i.e.,PFP ***-free group;women with PFP ***-free women;men with PFP ***-free men).Results:Women with PFP presented significantly higher BMI,%BFBiompedance,and %BFSkinfold,and lower skeletal muscle mass compared to pain-free women(p≤0.04;effect size:-0.47 to 0.85).Men with PFP and men and women combined had no differences in BMI,%BFBioimpedance,%BFSkinfold,and skeletal muscle mass compared to their respective pain-free groups(p> 0.05).Conclusion:Our findings indicate that BMI and body composition measures should be considered as part of the evaluation and management of people with PFP,especially in women,who have demonstrated higher BMI and body fat and lower skeletal muscle mass compared to pain-free *** studies should not assess body composition measures in a mixed-sex population without distinguishing men participants from women participants.

关键词： Body composition Body mass index Patellofemoral pain syndrome Skinfold thicknessTagedend

Supercritical fluid technology as a sustainable alternative method for textile dyeing:An approach on waste,energy,and CO_(2)emission reduction

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Journal of Environmental Sciences 2024年第6期140卷 123-145页

作者： Carlos Rafael silva de oliveira Patrícia Viera de oliveira Leandro Pellenz Catia Rosana Lange de Aguiar Afonso Henrique da silva Júnior Federal University of Santa Catarina Textile Engineering Department2514 João Pessoa St.BlumenauSC89036-004Brazil Federal University of Santa Catarina Chemical Engineering DepartmentS/n Biotério Central St.FlorianópolisSC88040-900Brazil

The clothing industry is considered one of the most polluting industries on the planet due to the high consumption of water,energy,chemicals/dyes,and high generation of solid waste and *** with environmental concerns,the textile ennoblement sector is the most critical of the textile production chain,especially the traditional dyeing *** an alternative to current problems,dyeing with supercritical CO_(2)(scCO_(2))has been presented as a clean and efficient process for a sustainable textile *** fluid dyeing(SFD)has shown a growing interest due to its significant impact on environmental preservation and social,economic,and financial *** main SFD benefits include economy and reuse of non-adsorbed dyes;reduction of process time and energy expenditure;capture of atmospheric CO_(2)(greenhouse gas);use and recycling of CO_(2)in SFD;generation of carbon credits;water-free process;effluent-free process;reduction of CO_(2)emission and auxiliary *** being still a non-scalable and evolving technology,SFD is the future of *** review presented a comprehensive overview of the environmental impacts caused by traditional processes and confronted the advantages of *** SFD technique was introduced,along with its latest advances and future *** and environmental gains were also discussed.

关键词： Textile industry Supercritical dyeing Sustainable processes Water free dyeing Energy saving Cleaner production

ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

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Journal of Forestry Research 2024年第1期35卷 83-89页

作者： Julia Isabella de Matos Rodrigues Walmer Bruno Rocha Martins Victor Pereira de oliveira Myriam Suelen da silva Wanzerley Hélio Brito dos Santos Júnior Francisco de Assis oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WHC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WHC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WHC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone

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Journal of Renewable Materials 2024年第2期12卷 285-304页

作者： Flavia oliveira Monteiro da silva Abreu Taysse Holanda Joice Farias do Nascimento Henety Nascimento Pinheiro Rachel Menezes Castelo Hélcio silva dos Santos Thais Benincá Patrícia da silva Malheiros Júlio César Sousa Prado Raquel de oliveira Fontenelle Maria Madalena de Camargo Forte Natural Polymers Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Polymeric Materials Laboratory PPGE3MFederal University of Rio Grande do SulPorto Alegre91501-970Brazil Natural Product Chemistry Laboratory PPGCNState University of CearáFortaleza60.714.903Brazil Food Hygiene and Microbiology Laboratory PPGCTAFederal University of Rio Grande do SulPorto Alegre91501-970Brazil Microbiology Laboratory Medicine SchoolFederal University of CearáSobral62010-560Brazil

With the increase in antimicrobial resistance,it has become necessary to explore alternative approaches for combating and preventing ***-cinnamaldehyde(CNM)and Benzyl4-amino(B4AM)are bioactive compounds derived from chalcones but with restricted solubility in aqueous *** can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials,with reduced side effects and prolonged *** objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages,to propose a stable formulation with antimicrobial *** showed that nanoemulsions presented high encapsulation efficiency,low polydispersity index(PDI)and particle size below 200 nm,indicating that emulsification was a suitable method for nanoemulsion *** with higher dosages exhibited significant antimicrobial effects when compared to free chalcones and positive ***,B4AM nanoemulsions at higher dosages showed expressive activity against Salmonella minnesota,with a 420%greater inhibitory response compared to the free form and showing equivalence to the positive *** nanoemulsions showed excellent inhibitory activity at the highest dosage,equivalent to the positive control against *** and Staphylococcus *** greater number of conjugated bonds in CNM increased the antimicrobial activity in comparison with B4AM,and the formation of nanometric domains enhanced the bioavailability,being a promising alternative for antimicrobial applications.

关键词： Polysaccharide nanoemulsions S.aureus S.minnesota chalcones alginate

Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado Nunes Pamela Castro-e-Souza Anselmo Alves de oliveira Bruno de Freitas Camilo Gislaine Cristina-Souza Lucio Marques Vieira-Souza Marcelo Augusto da silva Carneiro department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,development,and Evaluation(GRAde)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRAde:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

Is it possible to run after positive affective experiences instead of health benefits without tackling social inequalities?

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Journal of Sport and Health Science 2024年第6期13卷 756-758页

作者： Raphael H.O.Araujo Andre O.Werneck Gilmar M.de Jesus danilo R.P.silva Graduation Program in Health Sciences Londrina State UniversityLondrina 86057-970Brazil School of Public Health The University of QueenslandBrisbane QLD 4006Australia Center for Epidemiological Research in Nutrition and Health Department of NutritionSchool of Public HealthUniversidade de S~ao Paulo(USP)Sao Paulo 01246-904Brazil department of Psychological Medicine Institute of PsychiatryPsychology and NeuroscienceKing’s College LondonLondon SE58AFUK Public Health Post-Graduate Program State University of Feira de SantanaFeira de Santana 44036-900Brazil department of Physical Education Federal University of SergipeSao Cristov~ao 490100-000Brazil

We recently read the opinion piece titled“Why people should run after positive affective experiences instead of health benefits”,which was carried out by Maltagliati et al.^(1)and published in the Journal of Sport and Health *** article started an important discussion about a physical activity(PA)promotion approach that encourages the use of affective experience to PA *** we agree with the authors’point of view and believe that its message can generate an important insight for PA promotion,the authors presented a scenario where behavior change seems to be exclusively dependent on the *** the existence of other barriers to an active lifestyle(e.g.,social inequalities)could enhance the authors’suggested approach because many people live in conditions that reduce their opportunities to engage in affective experiences related to PA;furthermore,affective experiences can vary depending on individual context.

关键词： promotion inequalities furthermore

New avenues for the treatment of immunotherapy-resistant pancreatic cancer

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1134-1153页

作者： Luis Guilherme de oliveira silva Fabian Fellipe Bueno Lemos Marcel silva Luz Samuel Luca Rocha Pinheiro Mariana dos Santos Calmon Gabriel Lima Correa Santos Gabriel Reis Rocha Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Pancreatic cancer(PC)is characterized by its extremely aggressive nature and ranks 14th in the number of new cancer cases ***,due to its complexity,it ranks 7th in the list of the most lethal cancers *** pathogenesis of PC involves several complex processes,including familial genetic factors associated with risk factors such as obesity,diabetes mellitus,chronic pancreatitis,and *** in genes such as KRAS,TP53,and SMAD4 are linked to the appearance of malignant cells that generate pancreatic lesions and,consequently,*** this context,some therapies are used for PC,one of which is immunotherapy,which is extremely promising in various other types of cancer but has shown little response in the treatment of PC due to various resistance mechanisms that contribute to a drop in immunotherapy *** is therefore clear that the tumor microenvironment(TME)has a huge impact on the resistance process,since cellular and non-cellular elements create an immunosuppressive environment,characterized by a dense desmoplastic stroma with cancerassociated fibroblasts,pancreatic stellate cells,extracellular matrix,and immunosuppressive *** to this are genetic mutations in TP53 and immunosuppressive factors that act on T cells,resulting in a shortage of CD8+T cells and limited expression of activation markers such as *** this way,finding new strategies that make it possible to manipulate resistance mechanisms is ***,techniques such as the use of TME modulators that block receptors and stromal molecules that generate resistance,the use of genetic manipulation in specific regions,such as microRNAs,the modulation of extrinsic and intrinsic factors associated with T cells,and,above all,therapeutic models that combine these modulation techniques constitute the promising future of PC ***,this study aims to elucidate the main mechanisms of resistance to immunotherapy in PC and new ways of manipulating thi

关键词： Pancreatic cancer Immunotherapy Resistance Tumor microenvironment manipulation Combined immunotherapy

Hydrocarbon indication in Rio Bonito Formation sandstone:Implication for CO_(2)storage in São Paulo,Brazil

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Energy Geoscience 2024年第1期5卷 331-341页

作者： Richardson M.Abraham-A Haline V.Rocha Saulo B.de oliveira Colombo C.G.Tassinarri Orlando C.da silva Institute of Energy and Environment University of São PauloSão PauloBrazil Research Centre for Greenhouse Gas Innovation University of São PauloSão PauloBrazil

São Paulo State has witnessed CO_(2)storage-based investigations considering the availability of suitable geologic structures and proximity to primary CO_(2)source sinks related to bioenergy and carbon capture and storage(BECCS)*** current study presents the hydrocarbon viability evaluations and CO_(2)storage prospects,focusing on the sandstone units of the Rio Bonito *** objective is to apply petrophysical evaluations with geochemical inputs in predicting future hydrocarbon(gas)production to boost CO_(2)storage within the study *** study used data from eleven wells with associated wireline logs(gamma ray,resistivity,density,neutron,and sonic)to predict potential hydrocarbon accumulation and fluid mobility in the investigated *** samples(shale and carbonate)obtained from depths>200 m within the study location have shown bitumen *** geochemistry data of the Rio Bonito Formation shale beds suggest they are potential hydrocarbon source rocks and could have contributed to the gas accumulations within the sandstone *** drilled well data,e.g.,CB-1-SP and TI-1-SP,show hydrocarbon(gas)presence based on the typical resistivity and the combined neutron-density responses at depths up to 3400 m,indicating the possibility of other hydrocarbon members apart from the heavy oil(bitumen)observed from the near-surface rocks *** the three-dimensional(3-D)model,the free fluid indicator(FFI)is more significant towards the southwest and southeast of the area with deeper depths of occurrence,indicating portions with reasonable hydrocarbon recovery rates and good prospects for CO_(2)injection,circulation and permanent ***,future studies based on contemporary datasets are required to establish the hydrocarbon viability further,foster gas production events,and enhance CO_(2)storage possibilities within the region.

关键词： ParanáBasin Hydrocarbon indication Sandstone reservoirs Rio Bonito Formation CO_(2)storage Hydrocarbon recovery factor Fluid injection rate

Star power: harnessing the reactive astrocyte response to promote remyelination in multiple sclerosis

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Neural Regeneration Research 2024年第3期19卷 578-582页

作者： Markley silva oliveira Junior Laura Reiche Emerson Daniele Ines Kortebi Maryam Faiz Patrick Küry department of Neurology Neuroregeneration laboratoryMedical FacultyHeinrich-Heine-UniversityDüsseldorfGermany Institute of Medical Science University of TorontoTorontoCanada Division of Anatomy Department of SurgeryUniversity of TorontoTorontoCanada

Astrocytes are indispensable for central nervous system development and *** response to injury and disease,astrocytes are integral to the immunological-and the,albeit limited,repair *** this review,we will examine some of the functions reactive astrocytes play in the context of multiple sclerosis and related animal *** will consider the heterogeneity or plasticity of astrocytes and the mechanisms by which they promote or mitigate ***,we will discuss a set of biomedical strategies that can stimulate astrocytes in their promyelinating response.

关键词： astrocytes demyelination drug-based therapies myelin repair oligodendrocyte precursor cells reactive astrogliosis