检索结果-南通市图书馆

International Journal of Ophthalmology(English edition) 2016年第6期9卷 890-897页

作者： Pia Leon Ingrid Umari Alessandro Mangogna Andrea Zanei daniele tognetto University Eye Clinic of Trieste Ospedale MaggioreTrieste34125Italy Department of Medicine Surgery and Health SciencesUniversity of TriesteTrieste 34149Italy

AIM： To evaluate and compare the intraoperative parameters and postoperative outcomes of torsional mode and longitudinal mode of phacoemulsification. METHODS： Pertinent studies were identified by a computerized MEDLINE search from January 2002 to September 2013. The Meta-anaiysis is composed of two parts. In the first part the intraoperative parameters were considered： ultrasound time （UST） and cumulative dissipated energy （CDE）. The intraoperative values were also distinctly considered for two categories （moderate and hard cataract group） depending on the nuclear opacity grade. In the second part of the study the postoperative outcomes as the best corrected visual acuity （BCVA） and the endothelial cell loss （ECL） were taken in consideration. RESULTS： The UST and CDE values proved statistically significant in support of torsional mode for both moderate and hard cataract group. The analysis of BCVA did not present statistically significant difference between the two surgical modalities. The ECL count was statistically significant in support of torsional mode （P〈0.001）. CONCLUSION： The Meta -analysis shows the superiority of the torsional mode for intraoperative parameters （UST, CDE） and postoperative ECL outcomes.

关键词： conventional (longitudinal) phacoemulsi-fication phacoemulsification torsional phacoemulsification

Effect of corneal light scatter on vision: a review of the literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2016年第3期9卷 459-464页

作者： Leopoldo Spadea Giorgia Maraone Francesca Verboschi Enzo Maria Vingolo daniele tognetto Department of Biotechnology and Medical-Surgical Sciences "Sapienza" University of Rome Eye Clinic Ospedale MaggioreUniversity of Trieste

The cornea is the transparent connective tissue window at the front of the *** physiological role of the cornea is to conduct external light into the eye,focus it,together with the lens,onto the retina,and to provide rigidity to the entire ***,good vision requires maintenance of the transparency and proper refractive shape of the *** surface structures irregularities can be associated with wavefront aberrations and scattering *** scattering in the human cornea causes a reduction of visual *** fact,the cornea must be transparent and maintain a smooth and stable curvature since it contributes to the major part of the focusing power of the *** most cases,a simple examination of visual acuity cannot demonstrate the reduction of visual quality secondary light *** fact,clinical techniques for examining the human cornea in vivo have greatly expanded over the last few *** measurement of corneal back scattering qualifies the degree of corneal *** measurement of corneal forward-scattering quantifies the amount of visual impairment that is produced by the alteration of *** aim of this study was to review scattering in the human cornea and methods of measuring it.

关键词： cornea haze light photorefraetive keratectomy scattering vision

Combined Descemet stripping automated endothelial keratoplasty and intravitreal dexamethasone implant for concomitant pseudophakic bullous keratopathy and cystoid macular edema

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2019年第5期12卷 866-869页

作者： Gabriella Cirigliano Marco R Pastore Alberto A Perrotta Chiara De Giacinto daniele tognetto Eye Clinic Department of Medical Surgical Sciences and HealthUniversity of Trieste

Dear Editor,Endothelial cell density decreases with age and in various ocular conditions,including corneal endotheliitis,uveitis,pseudoexfoliation syndrome,and birth injury(1)The reduction of endothelial cell density is exacerbated over time after intraocular surgery(1)Descemet stripping automated endothelial keratoplasty(DSAEK)is considered the primary procedure for patients with only endothelial dysfunction.

关键词： PBK Figure Combined Descemet stripping automated endothelial keratoplasty and intravitreal dexamethasone implant for concomitant pseudophakic bullous keratopathy and cystoid macular edema IOL IOP

Correction of low corneal astigmatism in cataract surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第4期8卷 719-724页

作者： Pia Leon Marco Rocco Pastore Andrea Zanei Ingrid Umari Meriem Messai Corrado Negro daniele tognetto University Eye Clinic of Trieste Ospedale Maggiore University of Trieste

· AIM: To evaluate and compare aspheric toric intraocular lens(IOL) implantation and aspheric monofocal IOL implantation with limbal relaxing incisions(LRI) to manage low corneal astigmatism(1.0-2.0 D) in cataract surgery.· METHODS: A prospective randomized comparative clinical study was performed. There were randomly recruited 102 eyes(102 patients) with cataracts associated with corneal astigmatism and divided into two groups. The first group received toric IOL implantation and the second one monofocal IOL implantation with peripheral corneal relaxing incisions. Outcomes considered were: visual acuity, postoperative residual astigmatism, endothelial cell count, the need for spectacles, and patient satisfaction. To determine the postoperative toric axis, all patients who underwent the toric IOL implantation were further evaluated using an OPD Scan III(Nidek Co, Japan). Follow-up lasted 6mo.· RESULTS: The mean uncorrected distance visual acuity(UCVA) and the best corrected visual acuity(BCVA) demonstrated statistically significant improvement after surgery in both groups. At the end of the follow-up the UCVA was statistically better in the patients with toric IOL implants compared to those patients who underwent implantation of monofocal IOL plus LRI. The mean residual refractive astigmatism was of 0.4 D for the toric IOL group and 1.1 D for the LRI group(P <0.01). No difference was observed in the postoperative endothelial cell count between the two groups.· CONCLUSION: The two surgical procedures demonstrated a significant decrease in refractive astigmatism. Toric IOL implantation was more effective and predictable compared to the limbal relaxing incision.

关键词： low corneal astigmatism toric intraocular lenses limbal relaxing incisions cataract surgery visual acuity

Spontaneous or secondary to intravitreal injections of anti-angiogenic agents retinal pigment epithelial tears in age-related macular degeneration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2014年第4期7卷 681-685页

作者： Pia E.Leon Sandro Saviano Andrea Zanei Marco R.Pastore Elvira Guaglione Alessandro Mangogna daniele tognetto University Eye Clinic of Trieste Ospedale Maggiore

·AIM:Toevaluatethevisualfunctionevolutionofretinal pigment epithelial(RPE) tears in patients with age-related macular degeneration(AMD) according to type of occurrence [spontaneous or secondary to anti-vascular endothelial growth factor(anti-VEGF) injection] and the topographic location of the tear after a two-year followup period.·METHODS: A total of 15 eyes of 14 patients with RPE tears in exudative AMD were analyzed retrospectively at the University Eye Clinic of Trieste. Inclusion criteria were: patient age of 50 or older with AMD and RPE tears both spontaneous occurring or post anti-VEGF treatment. Screening included: careful medical history,complete ophthalmological examination, fluorescein angiography(FA), indocyanine green angiography(ICG),autofluorescence and infrared imaging and optical coherence tomography(OCT). Patients were evaluated every month for visual acuity(VA), fundus examination and OCT. Other data reported were: presence of PED,number of injections before the tear, location of the lesion.·RESULTS:Meanfollow-up was24wk(SD±4wk). Atotal of 15 eyes were studied for RPE tear. In 6 cases(40%),the RPE tears occurred within two years of anti-VEGF injections the others occurred spontaneously. In 13cases(86.6%), the RPE tear was associated with pigment epithelial detachment(PED). In 7 cases(46.6%), the RPE tear occurred in the central area of the retina and involved the fovea. Two lesions were found in the parafoveal region, six in the extra-macular area. In all cases visual acuity decreased at the end of the follow-up period(P <0.01) independently of the type or the topographical location of the lesion.·CONCLUSION: RPE tear occurs in exudative AMD as a spontaneous complication or in relation to anti-VEGF injections. Visual acuity decreased significantly and gradually in the follow-up period in all cases. No correlation was found between visual loss and the type of onset or the topographic location of the tears.

关键词： retinal pigment epithelial age-related macular degeneration tears visual acuity anti-vascular endothelial growth factor treatment

Combined therapy with bevacizumab and photodynamic therapy for myopic choroidal neovascularization: A oneyear follow-up controlled study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2014年第2期7卷 335-339页

作者： Sandro Saviano Rita Piermarocchi Pia E.Leon Alessandro Mangogna Andrea Zanei Fabiano Cavarzeran Sc daniele tognetto University Eye Clinic University of TriesteOspedale Maggiore Trieste 34129 Italy Eye Clinic of Padova University of Padova

AIMTo evaluate the efficacy and safety of a combined treatment for myopic choroidal neovascularization (CNV) using photodynamic therapy (PDT) and intravitreal bevacizumab and to compare it with intravitreal bevacizuma... 详细信息

关键词： bevacizumab combined therapy myopia neovascularization photodynamic therapy

Rebound Tonometry in Cataract Surgery: Comparison with Goldmann Applanation Tonometry

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Ophthalmology 2018年第1期8卷 1-11页

作者： Chiara De Giacinto Rossella D’Aloisio Sara Trovarelli Agostino Accardo Odilla Vattovani daniele tognetto Department of Medicine Surgery and Health Sciences University of Trieste Trieste Italy Department of Industrial and Information Technology University of Trieste Trieste Italy

Purpose: to compare the rebound tonometer ICare? (RT) with the Goldmann applanation tonometer (GAT) in cataract surgery and to assess the influence of central corneal thickness (CCT) on intraocular pressure (IOP) measurements. Design: retrospective, comparative study. Methods: a total of 472 patients underwent IOP measurement using RT (time 0 = RTa). GAT IOP measurement was performed 5 minutes later, followed by a second RT IOP measurement after other 5 minutes (RTa + 10 min = RTb). CCT was obtained by ultrasound pachymetry. In 106 patients IOP was measured by means of RT and GAT before clear corneal cataract surgery (RT1 and GAT1) and at one day postoperatively (RT2 and GAT2). Results: RT IOP values > 5 mmHg were overestimated, while RT IOP values Conclusion: our results showed a good agreement between measurements obtained with RT and GAT in pre and postoperative cataract surgery, although a significant statistically difference was found between RT and GAT measurements performed postoperatively. Moreover, CCT is a parameter to be considered for the IOP measurement, especially for values obtained with RT.

关键词： Applanation Tonometer Cataract Surgery Intraocular Pressure Pachymetry Rebound Tonometer

Genetic signatures of ERCC1 and ERCC2 expression,along with SNPs variants,unveil favorable prognosis in SCLC patients undergoing platinum-based chemotherapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2025年第1期33卷 45-55页

作者： ENRICO CALIMAN SARA FANCELLI FEDERICO SCOLARI ADRIANO PASQUI CLARA MANNESCHI daniele LAVACCHI FRANCESCA MAZZONI FRANCESCA GENSINI VALERIA PASINI CAMILLA EVA COMIN LUCA VOLTOLINI SERENA PILLOZZI LORENZO ANTONUZZO Clinical Oncology Unit Careggi University HospitalFlorence50134Italy Department of Experimental and Clinical Medicine University of FlorenceFlorence50134Italy Department of Health Sciences University of FlorenceFlorence50134Italy Medical Oncology Unit Careggi University HospitalFlorence50134Italy Department of Experimental and Clinical Biomedical Sciences“Mario Serio” University of FlorenceFlorence50134Italy Section of Anatomic Pathology Department of Health SciencesUniversity of FlorenceFlorence50139Italy Section of Surgery Histopathology and Molecular PathologyUniversity of FlorenceFlorence50139Italy Thoracic Surgery Unit Careggi University HospitalFlorence50134Italy

Background:Platinum chemotherapy(CT)remains the backbone of systemic therapy for patients with smallcell lung cancer(SCLC).The nucleotide excision repair(NER)pathway plays a central role in the repair of the DNA damage exerted by platinum *** in this repair mechanism may affect patients’*** and Methods:We conducted a retrospective analysis of data from 38 patients with extensive disease(ED)-SCLC who underwent platinum-CT at the Clinical Oncology Unit,Careggi University Hospital,Florence(Italy),from 2015 to *** expression analysis and single nucleotide polymorphism(SNP)characterization of three NER pathway genes—namely ERCC1,ERCC2,and ERCC5—were performed on patient tumor ***:Overall,elevated expression of ERCC genes was observed in SCLC patients compared to healthy *** with low ERCC1 and ERCC5 expression levels exhibited a better median progression-free survival(mPFS=7.1 vs.4.9 months,p=0.39 for ERCC1 and mPFS=6.9 vs.4.8 months,p=0.093 for ERCC5)and overall survival(mOS=8.7 vs.6.0 months,p=0.4 for ERCC1 and mOS=7.2 vs.6.2 months,p=0.13 for ERCC5).Genotyping analysis of five SNPs of ERCC genes showed a longer survival in patients harboring the wild-type genotype or the heterozygous variant of the ERCC1 rs11615 SNP(p=0.24 for PFS and p=0.14 for OS)and of the rs13181 and rs1799793 ERCC2 SNPs(p=0.43 and p=0.26 for PFS and p=0.21 and p=0.16 for OS,respectively)compared to patients with homozygous mutant ***:The comprehensive analysis of ERCC gene expression and SNP variants appears to identify patients who derive greater survival benefits from platinum-CT.

关键词： Small cell lung cancer(SCLC) Nucleotide excision repair(NER)pathway ERCC genes Single nucleotide polymorphisms(SNPs) Platinumchemotherapy(CT)

On the Proper Homotopy Invariance of the Tucker Property

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2007年第3期23卷 571-576页

作者： daniele Ettore OTERA Universitádi Palermo Dipartimento di Matematica ed Applicazionivia Archirafi 3490123-PalermoItaly and Université Paris-SudMathématiquesBt 42591405 Orsay Cedex-France

A non-compact polyhedron P is Tucker if, for any compact subset K begong to P, the fundamental group π1 （P - K） is finitely generated. The main result of this note is that a manifold which is proper homotopy equivalent to a Tucker polyhedron is Tucker. We use Poenaru＇s theory of the equivalence relations forced by the singularities of a non-degenerate simplicial map.

关键词： proper homotopy Φ/ψ-theory tucker property

A recursive implementation of the ALIENOR optimization method

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International Journal of Intelligent Computing and Cybernetics 2021年第2期14卷 81-103页

作者： daniele Peri National Research Council(CNR) Istituto per le Applicazioni del Calcolo“Mauro Picone”–IACRomaItaly

Purpose-A recursive scheme for the ALIENOR method is proposed as a remedy for the difficulties induced by the method.A progressive focusing on the most promising region,in combination with a variation of the density of the alpha-dense curve,is ***/methodology/approach-ALIENOR method is aimed at reducing the space dimensions of an optimization problem by spanning it by using a single alpha-dense curve:the curvilinear abscissa along the curve becomes the only design parameter for any design *** a counterpart,the transformation of the objective function in the projected space is much more difficult to ***-A fine tuning of the procedure has been performed in order to identity the correct balance between the different elements of the *** proposed approach has been tested by using a set of algebraic functions with up to 1,024 design variables,demonstrating the ability of the method in solving large scale optimization *** an industrial application is ***/value-In the knowledge of the author there is not a similar paper in the current literature.

关键词： ALIENOR optimization Global optimization Lipschitzian optimization Reduced order base