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Age and petrogenesis of the newly discovered Early Permian granite in the Kumtor gold field， Kyrgyz Tien-Shan

Journal of Earth Science 2024年

作者： Kyiazbek Asilbekov Rustam Orozbaev Etienne Skrzypek Christoph Hauzenberger Elena Ivleva daniela Gallhofer Jian-Feng Gao Nikolay Pak Anatoliy Shevkunov Anatoliy Bashkirov Aizat Zhaanbaeva Institute of Geology， National Academy of Sciences of the Kyrgyz Republic Institute of Earth Sciences， University of Graz State Key Laboratory of Ore Deposit Geochemistry， Institute of Geochemistry， Chinese Academy of Sciences Kumtor Gold Company CJSC

Permian intrusions are widespread in the Middle and Southern Tien Shan， with fewer occurrences in the Northern Tien-Shan. Notably， many of these intrusions are spatially associated with a variety of ore deposits， indicating a significant link between magmatic activity and mineralization processes in these areas. We studied granite samples recently recovered from drilling in the Kumtor gold field to evaluate their potential relationships with gold mineralization. We report major and trace element geochemistry， zircon U-Pb age and Hf isotope data for this so-called Kumtor granite. The Kumtor granite is metaluminous to peraluminous and belongs to the high-K and calc-alkaline series with I-type geochemical characteristics. The relatively high K2O and Na2O concentrations and low high field strength elements （HFSE） and heavy rare earth elements （HREE）， the presence of biotite within these I-type granites， together with their low zircon saturation temperatures （731–779 °C）， suggest that they were likely derived from a hydrous source formed by dehydration melting of mica-bearing， medium- to high-K metabasaltic rocks. Our zircon U-Pb dating results indicate that the Kumtor granite intruded at 293 ± 1.7 Ma， which is consistent with the age range of other Middle Tien-Shan granitoids. The zircon Hf isotopic composition is εHf（t）= –7.56 to –5.05， indicating an ancient （1.39 to 1.52 Ga） crustal origin. Petrographical， geochemical and geochronological data indicate that the Kumtor granite is similar to leuco-granites of the Terekty complex. Our results indicate that the Kumtor granite was emplaced in the early Permian in a post-collision setting and may have temporal and genetic relationships with gold mineralization.

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ICF框架下运动疗法对慢性非特异性颈痛效果的Meta分析

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中国康复理论与实践 2024年第7期30卷 778-788页

作者：温艳飞杨露班玥 Ykabaru daniela BERBESI NORIEGA 张郝琪王丽刘华首都体育学院北京市100191

目的基于《国际功能、残疾和健康分类》(ICF)框架,系统评价运动疗法对慢性非特异性颈痛(CNSNP)患者身体结构、功能、活动和参与等方面的干预效果。方法构建PICO架构,系统检索CBM、万方、维普、中国知网、Cochrane Library、Embase、Pu... 详细信息

目的基于《国际功能、残疾和健康分类》(ICF)框架,系统评价运动疗法对慢性非特异性颈痛(CNSNP)患者身体结构、功能、活动和参与等方面的干预效果。方法构建PICO架构,系统检索CBM、万方、维普、中国知网、Cochrane Library、Embase、PubMed和Web of Science等中、英文数据库,纳入有关运动疗法干预CNSNP患者的随机对照试验,时间范围为建库至2024年3月。采用Cochrane偏倚风险评估工具和物理治疗证据数据库(PEDro)量表对纳入文献进行质量评价,采用GRADE对结局指标进行证据质量评价,采用RevMan 5.3进行数据合并和分析,采用Stata 18.0进行偏倚风险评估。结果最终纳入11篇文献,共668例患者。PEDro量表评分5~8分。运动疗法类型包括肌力训练、稳定性训练、本体感觉训练、瑜伽和普拉提等;对照组包括空白对照、物理因子治疗和健康教育。运动疗法可显著增加患者颅椎角(SMD=0.84, 95%CI 0.42~1.26, P <0.001),降低疼痛视觉模拟量表评分(SMD=-2.05,95%CI-2.58~-1.52, P <0.001),提高压力疼痛阈值(MD=112.27, 95%CI 75.03~149.50, P <0.001),提高颈椎前屈(SMD=1.24, 95%CI 0.34~2.15, P=0.007)、侧屈(SMD=1.52, 95%CI 0.40~2.65, P=0.008)关节活动度,提高颈深屈肌耐力(SMD=1.02, 95%CI 0.10~1.94, P=0.03),改善颈椎关节位置觉(SMD=-1.00,95%CI-1.47~-0.53, P <0.001),但对于改善后屈(SMD=0.85, 95%CI-1.04~2.75, P=0.38)、旋转(SMD=1.65, 95%CI-0.35~3.65, P=0.11)关节活动度的效果不显著;运动疗法还能降低患者颈椎功能障碍指数评分(MD=-11.88, 95%CI-16.09~-7.68, P <0.001),对健康调查简表评分效果不显著(MD=19.04, 95%CI-3.00~41.08, P=0.09)。结论运动疗法可以改善CNSNP患者的异常姿势、疼痛、前屈和侧屈运动、颈屈肌耐力和关节位置觉,改善功能障碍,但对提高颈部后屈和旋转运动,改善生活质量方面仍需进一步的研究。

关键词：慢性非特异性颈痛运动国际功能、残疾和健康分类 Meta分析

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星巴克人手不足导致顾客不满

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商业周刊（中文版） 2024年第10期 12-14页

作者： daniela Sirtori 孟洁冰(译) 不详

星巴克的员工表示,人手不足导致顾客等待时间升、订单未完成和销量下降。星巴克的咖啡师说,他们正面临一个令人担忧的问题:饮品订单接而至,但制作饮品的人却越来越少。据员工和经理透露,在一些门店,一年前还有五个人制作冰玛奇朵和双份... 详细信息

星巴克的员工表示,人手不足导致顾客等待时间升、订单未完成和销量下降。星巴克的咖啡师说,他们正面临一个令人担忧的问题:饮品订单接而至,但制作饮品的人却越来越少。据员工和经理透露,在一些门店,一年前还有五个人制作冰玛奇朵和双份浓缩咖啡,而现在只剩下三四个人,这些知情人因未获授权公开发言而要求不具名。

关键词：星巴克顾客等待时间门店顾客不满不具名知情人饮品订单

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Laparoscopic central pancreatectomy with gastro-pancreatic anastomosis for symptomatic serous cystadenoma:A case report and literature review

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 87-91页

作者： Giuseppe Frazzetta Antonino Picciurro Angela Maffongelli Irene Vitale Francesco Vitale daniela Scimeca Michele Amata Anna Calì Ambra Bonaccorso Barbara Scrivo Vincenzo Di Martino Elisabetta Conte Filippo Mocciaro Roberto Di Mitri Pierenrico Marchesa Oncologic Surgery Unit ARNAS Civico HospitalPalermo 90100Italy Gastroenterology Unit ARNAS Civico HospitalPalermo 90100Italy

Surgery for lesions of the proximal part of the pancreatic body or neck can be challenging,and when enucleation is not possible,central pancreatectomy is an *** central pancreatic resection is rarely described worldwide;it is considered a difficult procedure mainly because of the risk of double pancreatic fistula developing at two sites of ***,it seems to be an excellent alternative to distal pancreatectomy or pancreaticoduodenectomy,with the advantages of preserving functioning parenchyma and reducing endocrine and exocrine ***,patients with pancreatic lesions requiring central resection are often managed with the open approach in many hospitals due to the complexity of total laparoscopic central pancreatectomy,which requires advanced laparoscopic skills,expertise and ***,we report a case of a 29-year-old female who underwent total laparoscopic central pancreatic resection with gastro-pancreatic anastomosis for symptomatic serous *** discuss the details of case management and review the relevant literature.

关键词： Laparoscopic Pancreatic surgery Central pancreatectomy Cystadenoma

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Analysis of Changes of Extreme Temperature during June to August Season over Tanzania

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Journal of Geoscience and Environment Protection 2024年第2期12卷 44-56页

作者： Justus Renatus Mbawala Huixin Li Jiani Zeng Daudi Mikidadi Ndabagenga Anqin Tan daniela Janine Beukes Praksed Mrosso Rafael Samuel Ekwacu Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/School of Atmospheric Sciences Nanjing University of Information Science and Technology Nanjing China National Meteorological Training Centre Kigoma Tanzania Tanzania Meteorological Authority (TMA) Forecasting Office Kilimanjaro International Airport (KIA) Kilimanjaro Tanzania Namibia Meteorological Service Windhoek Namibia Uganda National Meteorological Authority Kampala Uganda

Natural and human systems are exposed and vulnerable to climate extremes, which contributes to the repercussions of climate variability and the probability of disasters. The impacts of both natural and human-caused climate variability are reflected in the reported changes in climate extremes. Particularly at the local community levels in the majority of the regions, there is currently a dearth of information regarding the distribution, dynamics, and trends of excessive temperatures among the majority of Tanzanians. Over the years 1982-2022, this study examined trends in Tanzania’s extreme temperature over the June to August season. Based on the distinction between absolute and percentile extreme temperatures, a total of eight ETCCDI climate indices were chosen. Mann-Kendall test was used to assess the presence of trends in extreme climatic indices and the Sen’s Slope was applied to compute the extent of the trends in temperature extremes. The study showed that in most regions, there is significant increase of warm days and nights while the significant decrease of cold days and nights was evident to most areas. Moreover, nighttime warming surpasses daytime warming in the study area. The study suggests that anthropogenic influences may contribute to the warming trend observed in extreme daily minimum and maximum temperatures globally, with Tanzania potentially affected, as indicated in the current research. The overall results of this study reflect patterns observed in various regions worldwide, where warm days and nights are on the rise while cold days and nights are diminishing.

关键词： Indices Warm Days and Nights Cold Days and Nights ECA&D Tanzania

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Update on the use of 45S5 bioactive glass in the treatment of bone defects in regenerative medicine

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World Journal of Orthopedics 2024年第3期15卷 204-214页

作者： Dayane Maria Braz Nogueira Marcelie Priscila de Oliveira Rosso daniela Vieira Buchaim Mariana Schutzer Ragghianti Zangrando Rogério Leone Buchaim Department of Prosthodontics and Periodontics Bauru School of DentistryUniversity of São PauloBauru 17012-901Brazil Department of Biological Sciences Bauru School of DentistryUniversity of São PauloBauru 17012-901Brazil Medical School University Center of AdamantinaAdamantina 17800-000Brazil Postgraduate Program in Structural and Functional Interactions in Rehabilitation Postgraduate DepartmentUniversity of MaríliaMarília 17525-902Brazil

Bone regeneration is a critical area in regenerative medicine,particularly in orthopedics,demanding effective biomedical materials for treating bone defects.45S5 bioactive glass(45S5 BG)is a promising material because of its osteoconductive and bioactive *** research in this field continues to advance,keeping up-to-date on the latest and most successful applications of this material is *** achieve this,we conducted a comprehensive search on Pub-Med/MEDLINE,focusing on English articles published in the last *** search used the keywords“bioglass 45S5 AND bone defect”in *** found 27 articles,and after applying the inclusion criteria,we selected 15 studies for detailed *** of these studies compared 45S5 BG with other cement or scaffold *** comparisons demonstrate that the addition of various composites enhances cellular biocompatibility,as evidenced by the cells and their osteogenic ***,the use of 45S5 BG is enhanced by its antimicrobial properties,opening avenues for additional investigations and applications of this biomaterial.

关键词： Biocompatible materials Bioglass Bone regeneration

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Geophysical evidence of a large occurrence of mud volcanoes associated with gas plumbing system in the Ross Sea(Antarctica)

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Geoscience Frontiers 2024年第1期15卷 304-324页

作者： Martina Busetti Riccardo Geletti Dario Civile Chiara Sauli Giuseppe Brancatelli Edy Forlin daniela Accettella Lorenza Barro Savonuzzi Laura De Santis Aldo Vesnaver Andrea Cova National Institute of Oceanography and Applied Geophysics–OGS Borgo Grotta Gigante 42/c34010 SgonicoTriesteItaly

Seafloor and buried reliefs occur along continental margin of the Ross Sea(Antarctica).These features are several kilometres wide and tens of metres high,exhibiting cone or flat-top dome *** studies have proposed a volcanic or glacial origin for these formations,but these hypotheses do not account for all the available *** this study,we use morpho-bathymetric data,intermediate resolution multichannel seismic and high resolution chirp profiles,as well as magnetic lines to investigate these clusters of *** employing targeted processing techniques to enhance the geophysical characterization of the seafloor and buried reliefs,and to understand the underlying geological features,we propose that the reliefs are mud *** of these formations appear to be associated with a plumbing system,as indicated by acoustic anomalies linked to sediment containing *** formations are likely fed by clayey source rocks of Miocene ***,other reliefs might be the result of mud mobilisation caused by gravity instability and fluid overpressure.

关键词： Ross Sea Antarctica Mud volcanoes Gas plumbing system Gas hydrate Bottom Simulating Reflector

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Broad Hormonal Responses Induced by Aluminum in Roots of Dwarf Transgenics of Solanum lycopersicum L. cv “Micro-Tom”

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American Journal of Plant Sciences 2024年第5期15卷 349-358页

作者： Arthur B. Rates daniela Boanares Daniele S. G. Pianetti Felipe Della-Torre Joni E. Lima Marcel G. C. França Department of Botany and Plant Physiology Laboratory Federal University of Minas Gerais Belo Horizonte Brazil

The spatial pattern distribution of plant hormones in response to aluminum (Al) toxicity in roots remains to be shown. This study was performed to assess the root hormonal accumulation and gene expression in response to Al toxicity in five transgenic miniature dwarf tomatoes cv. Micro-Tom (MT). MT and MT transgenics to acid indole acetic, cytokinin, gibberellin, abscisic acid and ethylene were cultivated in nutrient solutions containing different Al concentrations. Root growth elongation was measured and cellular damage was visualized by staining Evans’s blue. The GUS reporter gene staining technique was used to visualize hormonal changes in MT apex root tissues. Data indicated that the MT is sensitive to Al that induced significant growth inhibition and cellular damage. Al concentration of 27 μM was significantly toxic, inducing root apex darkening and inhibition of root development. The qualitative evaluation of GUS reporter gene expression showed intense crosstalk among all hormones studied, underscoring the complexity of signaling induced by Al in apex roots. Results point out to a major understanding of the hormonal signaling in response to Al toxicity, which may induce a change of root growth and architecture with growth inhibition and cell constraints modulated by all different hormones evaluated.

关键词： Gene Reporter Metal Plant Hormones Root Staining

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Feeding Calcium Salts of Linseed Oil on Metabolic Status and Reproductive Traits in Grazing Dairy Cows

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Open Journal of Animal Sciences 2024年第3期14卷 219-233页

作者： Jesica daniela Iorio Yaliska Moreno González Maria Florencia Olmeda Dino Curletto Daniel Edgardo Scandolo Martin Guillermo Maciel Rafael Alejandro Palladino Mauricio Javier Giuliodori Eloy Eduardo Salado School of Agriculture of the University of Buenos Aires (FAUBA) Buenos Aires Argentina Faculty of Agricultural Sciences National University of Lomas de Zamora (UNLZ) Lomas de Zamora Argentina Rafaela Agricultural Experiment Station National Institute of Agricultural Technology (INTA) Rafaela Argentina Faculty of Veterinary Science La Plata National University (FCV) La Plata Argentina

This experiment aimed to evaluate the effect of calcium salts of linseed oil (rich in alpha-linolenic acid (ALA, C18:3n-3) on metabolic and reproductive traits in high-producing dairy cows under grazing. Thirty-six Holstein dairy cows were randomly assigned, in a complete block design, to receive ALA supplementation (0.85 kg∙day−1 of calcium salts of linseed oil) or to remain as untreated control (CON). The concentrate was formulated to offer the same amount of energy across treatments (CON cows received an extra kg of corn to compensate for the higher energy density of ALA treatment). A PMR + Alfalfa pasture was offered to all cows at the same time. A fixed time artiﬁcial insemination (FTAI) at 80 DIM, preceded by a Presynch plus Ovsynch protocol was implemented for the first service and later, on return to estrus, heat detection and artiﬁcial insemination (AI) were performed. Pregnancy diagnosis was checked at 30, 42, 60, and 90 d after AI. Blood and milk samples were taken biweekly. Treatment affected plasma cholesterol concentration (160.36 vs. 186.70 mg∙dl−1, p = 0.03, for ALA and CON, respectively) and on size of corpus luteum (CL, 17.6 vs. 13.7 mm, p = 0.02, for ALA and CON, respectively). Supplementation tended (p = 0.136) to increase conception rate by 200 DIM (81.69% vs. 55.43% in ALA and CON cows, respectively). However, treatment had no effect (p > 0.05) on body weight (BW), body condition score (BCS), and circulating levels of beta-hydroxybutyrate (BHBA), glucose, insulin, growth hormone (GH) and insulin-like growth factor (IGF-I). Our results suggest that supplementation with calcium salts of linseed oil could enhance ovarian function without affecting energy metabolism in early lactation dairy cows.

关键词： α-Linolenic Acid Supplementation Reproduction Grazing Dairy Cows

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Relationship between the rs2241766 ADIPOQ Polymorphism in a Black African Population and the Occurrence of Type 2 Diabetes

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American Journal of Molecular Biology 2024年第2期14卷 97-106页

作者： Aude Syntia Mbang Bengone Rosalie Nikiema-Ndong Elisabeth Lendoye Alvine Sibylle Batou Edwige Nnegue Edzo Serge Bekale daniela Nsame Frédéric Da Dari Félix Ovono Abessolo Department of Chemistry-Biochemistry Faculty of Medicine University of Health Sciences Libreville Gabon Laboratory of Research in Biochemistry (LAREBIO) University of Sciences and Technology of Masuku Franceville Gabon Endocrinology Department University Hospital of Libreville Libreville Gabon Research Institute of Health Sciences Bobodioulasso Burkina Faso

Background: Type 2 diabetes mellitus (T2DM) is a metabolic disease, characterized by chronic hyperglycemia. This pathology is linked to various genes whose interaction with the environment promotes its development. The aim of this work was to determine the relationship between the rs2241766 (T/G) polymorphism of the ADIPOQ gene with type 2 diabetes in the black population. Material and Methods: This work was a case-control study, involving type 2 diabetics subjects (n = 94) and controls (n = 82). The study took place from September 2022 to September 2023. Patients were recruited in the Endocrinology Department of the Libreville University Hospital Center. Analysis was performed in the Biochemistry laboratory of the University of Health Sciences in Libreville and at the Research Institute of Health Sciences of Bobodioulasso. Genomic DNA was extracted using the protocol Qiagen kit and the PCR-RFLP method was used to determine the rs2241766 (T/G) polymorphism of the ADIPOQ gene. Results: Only 2 genotypes were found in this population, the TT genotype and the GT genotype. The proportions were not different between the two groups (p = 0.1095) neither the distribution of G and T alleles (p = 0.1095). On the other hand, the HDL hypocholesterolemia was frequent in subjects with the GT genotype compared to TT heterozygous (51.1% vs 48.9%, p = 0.0280;OR = 0.55 [0.30 - 1.01]). Conclusion: There was no association between the rs2241766 (T/G) variant of the ADIPOQ gene and the occurrence of type 2 diabetes in this population. On the other hand, a relationship between HDL hypocholesterolemia and the GT genotype has been established.

关键词： Type 2 Diabetes Mellitus Polymorphism rs2241766 ADIPOQ PCR-RFLP

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