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Feeding Calcium Salts of Linseed Oil on Metabolic Status and Reproductive Traits in Grazing Dairy Cows

Open Journal of Animal Sciences 2024年第3期14卷 219-233页

作者： Jesica daniela Iorio Yaliska Moreno González Maria Florencia Olmeda Dino Curletto Daniel Edgardo Scandolo Martin Guillermo Maciel Rafael Alejandro Palladino Mauricio Javier Giuliodori Eloy Eduardo Salado School of Agriculture of the University of Buenos Aires (FAUBA) Buenos Aires Argentina Faculty of Agricultural Sciences National University of Lomas de Zamora (UNLZ) Lomas de Zamora Argentina Rafaela Agricultural Experiment Station National Institute of Agricultural Technology (INTA) Rafaela Argentina Faculty of Veterinary Science La Plata National University (FCV) La Plata Argentina

This experiment aimed to evaluate the effect of calcium salts of linseed oil (rich in alpha-linolenic acid (ALA, C18:3n-3) on metabolic and reproductive traits in high-producing dairy cows under grazing. Thirty-six Holstein dairy cows were randomly assigned, in a complete block design, to receive ALA supplementation (0.85 kg∙day−1 of calcium salts of linseed oil) or to remain as untreated control (CON). The concentrate was formulated to offer the same amount of energy across treatments (CON cows received an extra kg of corn to compensate for the higher energy density of ALA treatment). A PMR + Alfalfa pasture was offered to all cows at the same time. A fixed time artiﬁcial insemination (FTAI) at 80 DIM, preceded by a Presynch plus Ovsynch protocol was implemented for the first service and later, on return to estrus, heat detection and artiﬁcial insemination (AI) were performed. Pregnancy diagnosis was checked at 30, 42, 60, and 90 d after AI. Blood and milk samples were taken biweekly. Treatment affected plasma cholesterol concentration (160.36 vs. 186.70 mg∙dl−1, p = 0.03, for ALA and CON, respectively) and on size of corpus luteum (CL, 17.6 vs. 13.7 mm, p = 0.02, for ALA and CON, respectively). Supplementation tended (p = 0.136) to increase conception rate by 200 DIM (81.69% vs. 55.43% in ALA and CON cows, respectively). However, treatment had no effect (p > 0.05) on body weight (BW), body condition score (BCS), and circulating levels of beta-hydroxybutyrate (BHBA), glucose, insulin, growth hormone (GH) and insulin-like growth factor (IGF-I). Our results suggest that supplementation with calcium salts of linseed oil could enhance ovarian function without affecting energy metabolism in early lactation dairy cows.

关键词： α-Linolenic Acid Supplementation Reproduction Grazing Dairy Cows

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Relationship between the rs2241766 ADIPOQ Polymorphism in a Black African Population and the Occurrence of Type 2 Diabetes

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American Journal of Molecular Biology 2024年第2期14卷 97-106页

作者： Aude Syntia Mbang Bengone Rosalie Nikiema-Ndong Elisabeth Lendoye Alvine Sibylle Batou Edwige Nnegue Edzo Serge Bekale daniela Nsame Frédéric Da Dari Félix Ovono Abessolo Department of Chemistry-Biochemistry Faculty of Medicine University of Health Sciences Libreville Gabon Laboratory of Research in Biochemistry (LAREBIO) University of Sciences and Technology of Masuku Franceville Gabon Endocrinology Department University Hospital of Libreville Libreville Gabon Research Institute of Health Sciences Bobodioulasso Burkina Faso

Background: Type 2 diabetes mellitus (T2DM) is a metabolic disease, characterized by chronic hyperglycemia. This pathology is linked to various genes whose interaction with the environment promotes its development. The aim of this work was to determine the relationship between the rs2241766 (T/G) polymorphism of the ADIPOQ gene with type 2 diabetes in the black population. Material and Methods: This work was a case-control study, involving type 2 diabetics subjects (n = 94) and controls (n = 82). The study took place from September 2022 to September 2023. Patients were recruited in the Endocrinology Department of the Libreville University Hospital Center. Analysis was performed in the Biochemistry laboratory of the University of Health Sciences in Libreville and at the Research Institute of Health Sciences of Bobodioulasso. Genomic DNA was extracted using the protocol Qiagen kit and the PCR-RFLP method was used to determine the rs2241766 (T/G) polymorphism of the ADIPOQ gene. Results: Only 2 genotypes were found in this population, the TT genotype and the GT genotype. The proportions were not different between the two groups (p = 0.1095) neither the distribution of G and T alleles (p = 0.1095). On the other hand, the HDL hypocholesterolemia was frequent in subjects with the GT genotype compared to TT heterozygous (51.1% vs 48.9%, p = 0.0280;OR = 0.55 [0.30 - 1.01]). Conclusion: There was no association between the rs2241766 (T/G) variant of the ADIPOQ gene and the occurrence of type 2 diabetes in this population. On the other hand, a relationship between HDL hypocholesterolemia and the GT genotype has been established.

关键词： Type 2 Diabetes Mellitus Polymorphism rs2241766 ADIPOQ PCR-RFLP

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Disaster Risk Governance as Assemblage: The Chilean Framework of the 1985 San Antonio Earthquake

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International Journal of Disaster Risk Science 2022年第6期13卷 878-889页

作者： daniela P.González Architecture and Urban Studies Pontifcal Catholic University of Chile7520245 SantiagoChile

The purpose of this article is to analyze disaster risk governance through assemblage theory, identifying how-during the altered political context of a military regime with a centralized disaster risk management as in the case of Chile in 1985-new actors emerge during the disaster response phase as a de/reterritorialization effect that is influenced by their agencies and relationships, disfiguring the edges of the assemblage. Based on this conceptualization, it is possible to investigate the interactions between the different actors, their power relations, and their reconfigurations in the governance exercise. For this purpose, we reviewed the response phase of the 1985 San Antonio earthquake that affected the central zone of Chile, where strategic functions, institutions, and forms of power are *** describe and visualize the actors during the response phase in the disaster risk governance framework, a map of actors was developed that identifies the existing relationships and their different weights. The central scale proved to be dominant and occupied a political space that was transfigured by its overrepresentation-enforced by allies such as the banking system and business associations-enhancing a neoliberal agenda. The leaps in scale from the central scale to the local scale cancel agency of the last, destabilizing its capacity to deal with the effects of the earthquake and isolating it from the decision-making processes. Consequently,delays in providing aid demonstrate that authoritarian governments do not provide better management in the disaster response phase.

关键词： Assemblage Chile Disaster response phase Disaster risk governance San Antonio earthquake

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LVMH路威酪轩集团董事会主席兼CEO 伯纳德·阿尔诺:我们的每项计划都着眼于未来

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商业周刊（中文版） 2024年第12期 42-49页

作者： BRAD STONE ANGELINA RASCOUET RUVEN AFANADOR(摄影) Jeannette Neumann Natalie Wong daniela Wei Shirley Zhao 杨飞(译) 不详

LVMH路威酪轩集团已将全球众多奢侈品牌收入囊中,如今又成为2024年巴黎奥运会的最大赞助商。阿尔诺认为,该集团作为法国文化旗手,有责任让奥运会取得成功每周六早上,伯纳德·阿尔诺(BernardArnault)都会在副手、保镖和子女轮流担当的随... 详细信息

LVMH路威酪轩集团已将全球众多奢侈品牌收入囊中,如今又成为2024年巴黎奥运会的最大赞助商。阿尔诺认为,该集团作为法国文化旗手,有责任让奥运会取得成功每周六早上,伯纳德·阿尔诺(BernardArnault)都会在副手、保镖和子女轮流担当的随从陪同下,花几个小时的时间巡查他供奉着手袋、时装、珠宝和昂贵手表的时尚神殿。

关键词：集团董事会奢侈品牌阿尔诺奥运会伯纳德 CEO 赞助商

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Application of machine learning techniques to simulate the evaporative fraction and its relationship with environmental variables in corn crops

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Ecological Processes 2022年第1期11卷 758-771页

作者： Terenzio Zenone Luca Vitale daniela Famulari Vincenzo Magliulo National Research Council Institute for Agricultural and Forestry Systems in the MediterraneanP.Le Enrico Fermi 180055 PorticiItaly National Research Council CNR Institute for BioeconomyVia P.Gobetti10140129 BolognaItaly

Background:The evaporative fraction(EF)represents an important biophysical parameter reflecting the distribution of surface available *** this study,we investigated the daily and seasonal patterns of EF in a multi-year corn cultivation located in southern Italy and evaluated the performance of five machine learning(ML)classes of algorithms:the linear regression(LR),regression tree(RT),support vector machine(SVM),ensembles of tree(ETs)and Gaussian process regression(GPR)to predict the EF at daily time *** adopted methodology consisted of three main steps that include:(i)selection of the EF predictors;(ii)comparison of the different classes of ML;(iii)application,cross-validation of the selected ML algorithms and comparison with the observed ***:Our results indicate that SVM and GPR were the best classes of ML at predicting the EF,with a total of four different algorithms:cubic SVM,medium Gaussian SVM,the Matern 5/2 GPR,and the rational quadratic *** com-parison between observed and predicted EF in all four algorithms,during the training phase,were within the 95%confidence interval:the R^(2)value between observed and predicted EF was 0.76(RMSE 0.05)for the medium Gaussian SVM,0.99(RMSE 0.01)for the rational quadratic GPR,0.94(RMSE 0.02)for the Matern 5/2 GPR,and 0.83(RMSE 0.05)for the cubic SVM *** results were obtained during the testing *** results of the cross-validation analysis indicate that the R^(2)values obtained between all iterations for each of the four adopted ML algorithms were basically constant,confirming the ability of ML as a tool to predict ***:ML algorithms represent a valid alternative able to predict the EF especially when remote sensing data are not available,or the sky conditions are not *** application to different geographical areas,or crops,requires further development of the model based on different data sources of soils,climate,and cropping systems.

关键词： Energy flux Evapotranspiration Eddy covariance Artificial intelligence

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Measuring Social Solidarity During Crisis:The Role of Design Choices

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Journal of Social Computing 2022年第2期3卷 139-157页

作者： Steffen Eger Dan Liu daniela Grunow the Center for Cognitive Interaction Technology(CITEC) Bielefeld UniversityBielefeld 33615Germany the Computer Science Department Technical University DarmstadtDarmstadt 64289Germany the Faculty of Social Sciences Goethe University FrankfurtFrankfurt 60629Germany

Building on our previous work,we assess how social solidarity towards migrants and refugees has changed before and after the onset of the COVID-19 pandemic,by collecting and analyzing a large,novel,and longitudinal dataset of migration-related *** this end,we first annotate above 2000 tweets for(anti-)solidarity expressions towards immigrants,utilizing two annotation approaches(experts ***).On these annotations,we train a BERT model with multiple data augmentation strategies,which performs close to the human upper *** use this high-quality model to automatically label over 240000 tweets between September 2019 and June *** then assess the automatically labeled data for how statements related to migrant(anti-)solidarity developed over time,before and during the COVID-19 *** findings show that migrant solidarity became increasingly salient and contested during the early stages of the pandemic but declined in importance since late 2020,with tweet numbers falling slightly below pre-pandemic levels in summer *** the same period,the share of anti-solidarity tweets increased in a sub-sample of COVID-19-related *** findings highlight the importance of long-term observation,pre-and post-crisis comparison,and sampling in research interested in crisis related *** one of our main contributions,we outline potential pitfalls of an analysis of social solidarity trends:for example,the ratio of solidarity and anti-solidarity statements depends on the sampling design,i.e.,tweet language,Twitter-user accounts’national identification(country known or unknown)and selection of relevant *** our sample,the share of anti-solidarity tweets is higher in native(German)language tweets and among“anonymous”Twitter users writing in German compared to English-language tweets of users located in Germany.

关键词： social solidarity crises COVID-19 natural language processing

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Early estimation of the number of hidden HIV infected subjects: An extended Kalman filter approach

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Infectious Disease Modelling 2023年第2期8卷 341-355页

作者： Paolo Di Giamberardino daniela Iacoviello Dept.of Computer Control and Management EngineeringSapienzaUniversity of RomeVia Ariosto 2500185RomeItaly

In the last decades several epidemic emergencies have been affecting the world,influencing the social relationships,the economics and the *** particular,starting in the early 080,the Acquired Immunodeficiency Syndrome,AIDS,is representing one of the most worrying sanitary emergency,that has caused up to now more than 25 million of dead *** infection is caused by the Human Immunodeficiency Virus,HIV,that may be transmitted by body fluids;therefore with wise behaviours the epidemic spread could rapidly be *** sanitary emergency is peculiar for the long incubation time:it can reach even 10 years,a long period in which the individual can unconsciously infect other *** identification of the number of infected unaware people,mandatory to define suitable containment measures,is here obtained by using the extended Kalman filter applied to a noisy model in which,reasonably,only the number of infected diagnosed patients is *** simulations and real data analysis support the effectiveness of the approach.

关键词： Epidemic modeling Infection spread HIV-AIDS Extended Kalman filter

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A Probabilistic Approach to the Evaluation of Seismic Resilience in Road Asset Management

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International Journal of Disaster Risk Science 2022年第1期13卷 114-124页

作者： Vittorio Nicolosi Maria Augeri Mauro D'Apuzzo Azzurra Evangelisti daniela Santilli Department of Enterprise Engineering“Mario Lucertini” University of Rome“Tor Vergata”00133 RomeItaly Department of Civil and Mechanical Engineering University of Cassino and Southern Lazio03043 CassinoItaly

Road networks are classified as critical infrastructure *** loss of functionality not only hinders residential and commercial activities,but also compromises evacuation and rescue after *** with risks to key strategic objectives is not new to asset management,and risk management is considered one of the core elements of asset *** analysis has recently focused on understanding and designing strategies for resilience,especially in the case of seismic events that present a significant hazard to highway transportation *** a review of risk and resilience concepts and metrics,an innovative methodology to stochastically assess the economic resources needed to restore damaged infrastructures,one that is a relevant and complementary element within a wider resilience-based framework,is *** original methodology is based on collecting and analyzing ex post reconstruction and hazard data and was calibrated on data measured during the earthquake that struck central Italy in 2016 and collected in the following recovery *** further improvements are needed,the proposed approach can be used effectively by road managers to provide useful information in developing seismic retrofitting plans.

关键词： Italy Resilience metrics Road asset management Road network resilience Seismic hazards

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Pathological features of tissues and cell populations during cancer cachexia

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Cell Regeneration 2022年第1期11卷 146-162页

作者： daniela Di Girolamo Shahragim Tajbakhsh Stem Cells&Development Department of Developmental&Stem Cell BiologyInstitut Pasteur75015 ParisFrance UMR 3738 CNRSInstitut Pasteur75015 ParisFrance

Cancers remain among the most devastating diseases in the human population in spite of considerable advances in limiting their impact on lifespan and *** multifactorial nature of cancers,as well as the number of tissues and organs that are affected,have exposed a considerable diversity in mechanistic features that are reflected in the wide array of therapeutic strategies that have been *** is manifested in a number of diseases ranging from cancers to diabetes and *** the context of cancers,a majority of patients experience cachexia and succumb to death due to the indirect effects of tumorigenesis that drain the energy reserves of different *** information is available on the pathophysiological features of cancer cachexia,however limited knowledge has been acquired on the resident stem cell populations,and their function in the context of these *** we review current knowledge on cancer cachexia and focus on how tissues and their resident stem and progenitor cell populations are individually affected.

关键词： Cancer cachexia Stem cells Tissue wasting

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Outcomes after combined excisional goniotomy and manual small incision cataract surgery

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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1707-1713页

作者： daniela Alvarez-Ascencio Gabriel Lazcano-Gomez Malik Y Kahook Department of Glaucoma Asociación Para Evitar la Ceguera en México(APEC)Mexico City 04030Mexico Department of Ophthalmology University of Colorado School of MedicineAuroraColorado 80145United States

AIM: To report the long-term outcomes of combined excisional goniotomy and manual small incision cataract surgery(MSICS).METHODS: This is a retrospective case series of patients with open angle glaucoma and visually significant cataracts that underwent combined excisional goniotomy and MSICS with one-year follow-up. The medical history, demographic information, and clinical characteristics of each case were recorded. Data regarding changes in vision, intraocular pressure(IOP), the number of glaucoma medications, and the evolution of the disease after surgery were reported. RESULTS: Three patients, with open angle glaucoma and cataracts underwent combined excisional goniotomy and MSICS without adverse events. All patients had improvement in vision compared to baseline measurements. The range of IOP at baseline was from 14 to 18 mm Hg and decrease to a range of 10 to 14 mm Hg after one year of follow-up. Additionally, two patients also decreased their dependence on IOP-lowering medications at the last follow up visit with one patient maintaining baseline level of medication ***: A combination of excisional goniotomy and MSICS illustrates both the safety and efficacy to treat patients with visually significant cataract and glaucoma. This procedure allows for a more cost-effective surgical approach that matches the needs of resource strained territories around the globe.

关键词： excisional goniotomy microincisional glaucoma surgery manual small incision cataract surgery Kahook Dual Blade

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