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Knowledge and Attitudes of Knust Pre-Clinical Dental Students towards Orthodontic Treatment

Open Journal of Stomatology 2024年第1期14卷 1-13页

作者： Ama Agyeibea Amuasi Ama B. Yeboah daniel K. Sabbah The Department of Child Oral Health and Orthodontics College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

Background: Orthodontics is a dental specialty focusing on correcting dental irregularities and malocclusion. Knowledge and attitudes towards orthodontic treatment are crucial for promoting oral health and overall well-being. Education and awareness play a vital role in ensuring optimal treatment outcomes and improving quality of life. Aim: This study aims to determine the knowledge and attitudes of Kwame Nkrumah University of Science and Technology (KNUST) pre-clinical dentistry students concerning orthodontic therapy. Methodology: This research is a quantitative descriptive cross-sectional study. The research used a non-random convenience sampling method to form the desired sample. For data collection, an interview-administered questionnaire was used over one month. The study set its sights on pre-clinical dental students in KNUST. A total of 150 questionnaires were printed to meet the sample size. Results: The results of the research showed that the knowledge level of KNUST pre-clinical students on orthodontic treatment and its nuances is quite limited. They however had a fair level of knowledge on the disease or ailment that orthodontic treatments solved (especially malocclusion). Their interest in orthodontic treatments on the other hand was quite significant, with a large number having interest in it. Conclusion: To conclude, KNUST pre-clinical students in Ghana although having a limited level of knowledge on orthodontic treatments have a keen interest in undergoing them regardless of the discomforts or the length of time.

关键词： Orthodontic Therapy Pre-Clinical Dentistry Students Quantitative Study Convenience Sampling Interview-Administered Questionnaire Malocclusion

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Study of Harmful Vaginal Practices of Women in the Municipality of Ouagadougou, Burkina Faso

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Health 2024年第5期16卷 425-438页

作者： daniel Dori Ramata Porgo Hyacinthe Zamané Nicolas Méda Rasmané Semdé Drug Development Laboratory African Center of Excellence for Training Research and Expertise in Pharmaceutical Sciences (CEA-CFOREM) Sciences and Health Doctoral School Training and Research Unit in Health Sciences Joseph Ki-Zerbo University Ouagadougou Burkina Faso Charles De Gaulle University Children’ s Hospital (CHUP-CDG) Ouagadougou Burkina Faso Public Health Laboratory Sciences and Health Doctoral School Joseph Ki-Zerbo University Ouagadougou Burkina Faso Mother and Child Laboratory Sciences and Health Doctoral School Joseph Ki-Zerbo University Ouagadougou Burkina Faso

Introduction: Vaginal practices include washing, altering, cutting, cleaning, enhancing, drying, tightening, lubricating, or loosening of the vagina, labia, clitoris, or hymen. This study aimed to investigate the different vaginal practices of women using non-pharmaceutical products. Methodology: This was a cross-sectional study with descriptive and analytical purposes that took place from January 15 to April 23, 2023, in the four largest markets in the municipality of Ouagadougou. This was performed using the data collection sheet in the KoboCollect application. Epi info 7.***.5.0. software was used for data analysis. For the analysis of associated factors, a p-value Results: In total, 977 women were surveyed. Among them, 43.19% underwent vaginal procedures using non-pharmaceutical products. The female practitioners were 34.34 ± 7.44 years old. The products used included plants, mineral substances, ointments, tablets, and solutions. Among the practicing women, 40.99% were looking for vaginal tightening. The main purpose was to maintain their partners (45.97%). Three-point thirty-two percent (3.32%) of the women who underwent vaginal procedures had reported adverse events. Conclusion: Raising awareness of the consequences of vaginal practices and encouraging women to go to a health center for any gynecological problem could significantly reduce the prevalence of vaginal practices.

关键词： Vaginal Practices Women Adverse Events Products

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola Mavillard Javier Perez-Florido Francisco M.Ortuño Amador Valladares Miren L.Álvarez-Villegas Gema Roldán Rosario Carmona Manuel Soriano Santiago Susarte Pilar Fuentes daniel López-López Ana María Nuñez-Negrillo Alejandra Carvajal Yolanda Morgado daniel Arteaga Rosa Ufano Pablo Mir Juan F.Gamella Joaquín Dopazo Carmen Paradas Macarena Cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de Medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain Centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain Centro de Salud Utrera Sur SevillaSpain Centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del Movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de Medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic disorders,a frequen... 详细信息

关键词： Server filtering massive

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以芳基重氮盐为芳基前体电化学合成芳基取代的苯并噻吩和菲

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电化学（中英文） 2024年第4期30卷 6-48页

作者：蓝丽媛蒋洋叶 R.daniel Little 曾程初北京工业大学环境与生命学院北京100124 Department of Chemistry&Biochemistry University of CaliforniaSanta BarbaraCalifornia 93106USA

芳基取代的苯并噻吩和菲是药物化学和材料科学中的重要结构单元。尽管已经投入了很多来制备这类化合物,并且已经开发了多种方法来构建2-取代的苯并噻吩核心结构,但仍然需要环境友好且有效的合成方法。基于我们以前的以芳基重氮盐为芳基... 详细信息

芳基取代的苯并噻吩和菲是药物化学和材料科学中的重要结构单元。尽管已经投入了很多来制备这类化合物,并且已经开发了多种方法来构建2-取代的苯并噻吩核心结构,但仍然需要环境友好且有效的合成方法。基于我们以前的以芳基重氮盐为芳基前体的电化学Minisci型芳基化反应,以及来自Konig小组的工作,本文使用成对电解以苯重氮盐为芳基前体来获得2-芳基苯并噻吩和9-芳基菲。首先,选择2-甲硫基苯重氮盐1a和4-甲基苯乙炔2a作为模型底物,通过考察溶剂、支持电解质、电极材料和电流密度来优化反应条件。经过大量的努力,发现在装备有石墨毡阳极、镍片阴极的单室电解池中,使用n-Bu_(4)NBF_(4)作为支持电解质,DMSO作为溶剂,控制在4mA·cm^(-2)条件下恒流电解,获得89%产率的所需产物3a。在最佳条件下,考察该电化学方案和底物范围的普适性。结果表明,烷基乙炔和芳基乙炔都适用于该方法,并成功地得到了一系列芳基取代的苯并噻吩衍生物。考虑到菲类化合物在药物化学和材料科学中的广泛应用,将此方案应用到菲衍生物的合成中,获得了相应的9-芳基菲衍生物。最后,通过循环伏安法分析了可能的机理。2-甲硫基苯重氮盐1a在CH_(3)CN中相对于Ag/Ag^(+)在-0.4 V处产生一个显著的不可逆还原峰,而在扫描电位窗口中没有检测到苯乙炔2a的信号。此外,尽管峰电流略有增加,2a的存在没有改变1a的还原峰电位。这些结果表明1a的还原比2a的还原容易。基于循环伏安分析和光催化结果,我们提出了成对电解机制,即芳基重氮盐1a在阴极的电化学还原产生芳基5a,然后芳基5a加成到苯乙炔上,在分子内环化后产生乙烯基6a和磺酰基7a。最后,7a的阳极氧化,接着用DMSO脱甲基化,生成目标产物3a。总之,我们发展了一种成对电解法来合成2-芳基苯并噻吩衍生物和9-芳基菲衍生物。该方案具有广泛的底物范围和官能团耐受性,进一步证明了芳基重氮盐作为多用途芳基自由基来源通过电化学还原产生芳基自由基的实用性。

关键词：苯并噻吩菲成对电合成芳基重氮盐芳基自由基

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How to establish an endoscopic bariatric practice

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World Journal of Gastrointestinal Endoscopy 2024年第4期16卷 178-186页

作者： daniel B Maselli Lauren L Donnangelo Brian Coan Christopher E McGowan Clinical Research True You Weight LossAtlantaGA 30342United States Clinical Research True You Weight LossCaryNC 27513United States

Obesity is a chronic,progressive,and relapsing disease of excess adiposity that contributes to more than two hundred medical conditions and is projected to affect more than half the adult population of the United States by the year *** the limited penetrance of traditional bariatric surgery,as well as the cost and adherence barriers to anti-obesity medications,there is growing interest in the rapidly evolving field of endoscopic bariatric therapies(EBTs).EBTs are minimally invasive,same-day,per-oral endoscopic procedures and include endoscopic sleeve gastroplasty,intragastric balloons,and endoscopic bariatric revisional *** field represents an exciting and innovative subspe-cialty within ***,building a successful endoscopic bariatric practice requires intentional,coordinated,and sustained efforts to overcome the numerous obstacles to *** barriers include acquisition of the technical and cognitive skillset,practice limitations including the availability of nutrition counseling,facility capabilities,direct-to-consumer marketing,and financial pressures such as facility and anesthesia *** the highest-volume center for metabolic and bariatric endoscopy in the United States,we provide insights into successfully establishing an endoscopic bariatric program.

关键词： Obesity Endoscopic bariatric therapies Bariatric endoscopy Endoscopic sleeve gastroplasty Intragastric balloon Practice management

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Oncologic outcomes with and without amniotic membranes in robotic-assisted radical prostatectomy:A propensity score matched analysis

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Asian Journal of Urology 2024年第1期11卷 19-25页

作者： Jonathan Noël daniel Stirt Marcio Covas Moschovas Sunil Reddy Abdel Rahman Jaber Marco Sandri Seetharam Bhat Travis Rogers Subuhee Ahmed Anya Mascarenhas Ela Patel Vipul Patel Advent Health Global Robotics Institute CelebrationFLUSA University of Central Florida College of Medicine OrlandoFLUSA Big and Open Data Innovation Laboratory University of BresciaItaly SUNY Upstate Medical University SyracuseNYUSA Kansas City University College of Medicine Kansas CityMOUSA Harvard University CambridgeMAUSA

Objective:Placement of human placenta derived grafts during robotic-assisted radical prostatectomy(RARP)hastens the return of continence and *** long-term impact on the oncologic outcomes remains to be *** objective was to determine the oncologic outcomes of patients with dehydrated human amnion chorion membrane(dHACM)at RARP compared to a matched ***:In a referral centre,from August 2013 to October 2019,599 patients used dHACM in bilateral nerve-sparing *** excluded patients with less than 12 months follow-up,simple prostatectomy,and unilateral *** with dHACM(amnio group)were 529,and were propensity score matched 1:1 to 2465 patients without dHACM(non-amnio group)and a minimum follow-up of 36 *** the time of RARP,dHACM was placed around the neurovascular bundle in the amnio *** and categorical variables in matched groups was tested by two-sample Kolmogorov-Smirnov test and Fisher's exact test *** measured were biochemical recurrence(BCR),adjuvant and salvage therapy ***:Propensity score matching resulted in two groups of 444 *** incidence functions for BCR did not show a difference between the groups(p=0.3).Patients in the non-amnio group required salvage therapy more frequently than the amnio group,particularly after partial nerve-sparing RARP(6.3%vs.2.3%,p=0.001).Limitations are the absence of prospective ***:The data suggest that using dHACM does not have a negative impact on BCR in *** of cancer specific and overall survival will require follow-up study to increase our understanding of these grafts’impact on prostate cancer biology.

关键词： Prostatectomy Prostatecancer Robotic Oncology Outcome Allograft Biomaterial Dehydrated human amnionchorion membrane

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Delivering a high-quality colonoscopy service fit for the 21st century

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第3期5卷 1-8页

作者： Brian Wing Kin Ip daniel Jin Keat Lee Kok Yang Tan Department of General Surgery Khoo Teck Puat HospitalSingapore 768828Singapore Department of Surgery Khoo Teck Puat HospitalSingapore 768828Singapore

Colorectal cancer(CRC)is the third most prevalent cancer *** is a concerning increase in its incidence among younger *** remains the gold standard for CRC *** the introduction of population-based bowel screening and increased public awareness,there has been a significant rise in referrals for *** providers worldwide will need to strategically evaluate how to allocate resources to adequately train the next generation of colonoscopists who will need to provide accurate endoscopic assessment and treatment for premalignant polyps and early *** review outlines the current workload challenges faced by colonoscopists whilst exploring emerging technologies such as artificial intelligence for adenoma ***,advanced endoscopic surgical techniques like endoscopic submucosal dissection are discussed.

关键词： Colonoscopy Colorectal cancer Bowel screening Polyps Adenoma

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Genetics of biochemical attributes regulating morpho-physiology of upland cotton under high temperature conditions

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Journal of Cotton Research 2024年第1期7卷 29-44页

作者： MAJEED Sajid CHAUDHARY Muhammad Tanees MUBARIK Muhammad Salman RANA Iqrar Ahmad SHABAN Muhammad TAN daniel KY JIA Yinhua DU Xiongming HINZE Lori AZHAR Muhammad Tehseen Federal Seed Certification and Registration Department Ministry of National Food Security and ResearchIslamabad 44090Pakistan Horticultural Research Institute National Agricultural Research CentreIslamabad 44000Pakistan Department of Biotechnology University of NarowalNarowal 51600Pakistan Centre of Agricultural Biochemistry and Biotechnology University of AgricultureFaisalabad 38400Pakistan Department of Plant Breeding and Genetics University of Agriculture FaisalabadSub-Campus BurewalaVehariPakistan Faculty of Science School of Life and Environ-mental SciencesPlant Breeding InstituteSydney Institute of AgricultureThe University of SydneySydneyNSW 2006Australia State Key Laboratory of Cotton Biology Institute of Cotton Research of Chinese Academy of Agri-cultural ScienceAnyang 455000China Agricultural Research Service USDASouthern Plains Agricultural Research CentreCollege StationTX 77845USA Department of Plant Breeding and Genetics University of AgricultureFaisal-abad 38400Pakistan School of Agriculture Sciences Zhengzhou UniversityZhengzhou 450000China.

Background Cotton is a strategically important fibre crop for global textile *** profoundly impacts several countries’industrial and agricultural *** cotton production is continuously threatened by the unpre-dictable changes in climate,specifically high *** heat-tolerant,high-yielding cotton cultivars with wide adaptability to be grown in the regions with rising temperatures is one of the primary objectives of modern cotton breeding ***,the main objective of the current study is to figure out the effective breed-ing approach to imparting heat tolerance as well as the judicious utilization of commercially significant and stress-tolerant attributes in cotton ***,the two most notable heat-susceptible(FH-115 and NIAB Kiran)and tolerant(IUB-13 and GH-Mubarak)cotton cultivars were spotted to develop filial and backcross populations to accom-plish the preceding study *** heat tolerant cultivars were screened on the basis of various morphological(seed cotton yield per plant,ginning turnout percentage),physiological(pollen viability,cell membrane thermostabil-ity)and biochemical(peroxidase activity,proline content,hydrogen peroxide content)*** The results clearly exhibited that heat stress consequently had a detrimental impact on every studied plant trait,as revealed by the ability of crossing and their backcross populations to tolerate high ***,when considering overall yield,biochemical,and physiological traits,the IUB-13×FH-115 cross went over particularly well at both normal and high temperature ***,overall seed cotton yield per plant exhibited a posi-tive correlation with both pollen viability and antioxidant levels(POD activity and proline content).Conclusions Selection from segregation population and criteria involving pollen viability and antioxidant levels concluded to be an effective strategy for the screening of heat-tolerant cotton g

关键词： Accessions Biochemical Breeding Cotton Generation mean analysis Heat stress

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Artificial Intelligence for Maximizing Agricultural Input Use Efficiency: Exploring Nutrient, Water and Weed Management Strategies

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1569-1598页

作者： Sumit Sow Shivani Ranjan Mahmoud F.Seleiman Hiba M.Alkharabsheh Mukesh Kumar Navnit Kumar Smruti Ranjan Padhan Dhirendra Kumar Roy Dibyajyoti Nath Harun Gitari daniel O.Wasonga Department of Agronomy Dr.Rajendra Prasad Central Agricultural UniversityPusaSamastipurBihar848125India Department of Plant Production College of Food and Agriculture SciencesKing Saud UniversityRiyadh11451Saudi Arabia Department of Crop Sciences Faculty of AgricultureMenoufia UniversityShibin El-Kom32514Egypt Department of Water Resources and Environmental Management Faculty of Agricultural TechnologyAl Balqa Applied UniversitySalt19117Jordan Division of Agronomy ICAR-Indian Agricultural Research InstitutePusa CampusNew Delhi110012India Department of Soil Science Dr.Rajendra Prasad Central Agricultural UniversityPusaSamastipurBihar848125India Department of Agricultural Science and Technology School of Agriculture and Environmental SciencesKenyatta UniversityNairobi43844Kenya Department of Crop Sciences University of Illinois Urbana-ChampaignUrbanaIL 61801USA

Agriculture plays a crucial role in the economy,and there is an increasing global emphasis on automating agri-cultural *** the tremendous increase in population,the demand for food and employment has also increased signiﬁ*** methods traditionally used to meet these requirements are no longer ade-quate,requiring solutions to issues such as excessive herbicide use and the use of chemical *** of technologies such as the Internet of Things,wireless communication,machine learning,artiﬁcial intelligence(AI),and deep learning shows promise in addressing these ***,there is a lack of comprehensive documentation on the application and potential of AI in improving agricultural input efﬁ*** address this gap,a desk research approach was used by utilizing peer-reviewed electronic databases like PubMed,Scopus,Goo-gle Scholar,Web of Science,and Science Direct for relevant *** of 327 initially identiﬁed articles,180 were deemed pertinent,focusing primarily on AI’s potential in enhancing yield through better management of nutrients,water,and *** into account researchﬁndings worldwide,we found that AI technologies could assist farmers by providing recommendations on the optimal nutrients to enhance soil quality and deter-mine the best time for irrigation or herbicide *** present status of AI-driven automation in agricul-ture holds signiﬁcant promise for optimizing agricultural input utilization and reducing resource waste,particularly in the context of three pillars of crop management,i.e.,nutrient,irrigation,and weed management.

关键词： Agriculture artiﬁcial intelligence crop management nutrient irrigation weed management resource use efﬁciency

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Finding biomarkers of experience in animals

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Journal of Animal Science and Biotechnology 2024年第3期15卷 925-944页

作者： Sarah Babington Alan J.Tilbrook Shane K.Maloney Jill N.Fernandes Tamsyn M.Crowley Luoyang Ding Archa H.Fox Song Zhang Elise A.Kho daniel Cozzolino Timothy J.Mahony Dominique Blache School of Agriculture and Environment The University of Western AustraliaCrawleyWA 6009Australia Centre for Animal Science The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia School of Veterinary Science The University of QueenslandGattonQLD 4343Australia School of Human Sciences The University of Western AustraliaCrawleyWA 6009Australia School of Medicine Deakin UniversityGeelongVIC 3217Australia Poultry Hub Australia University of New EnglandArmidaleNSW 2350Australia College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Centre for Nutrition and Food Sciences The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia

At a time when there is a growing public interest in animal welfare,it is critical to have objective means to assess the way that an animal experiences a *** is critical to ensure appropriate animal welfare *** behavioural,physiological,and neurobiological indicators that are used to assess animal welfare can verify the absence of extremely negative *** welfare is more than an absence of negative outcomes and an appropriate indicator should reflect the full spectrum of experience of an animal,from negative to *** this review,we draw from the knowledge of human biomedical science to propose a list of candidate biological markers(biomarkers)that should reflect the experiential state of non-human *** proposed biomarkers can be classified on their main function as endocrine,oxidative stress,non-coding molecular,and thermobiological *** also discuss practical challenges that must be addressed before any of these biomarkers can become useful to assess the experience of an animal in real-life.

关键词： Animal experience Animal welfare Biomarker Stress Welfare assessment

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