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Description of a novel robotic early post-prostatectomy anastomotic repair technique and institutional outcomes

Asian Journal of Urology 2024年第3期11卷 366-372页

作者： David Strauss Eric Cho Matthew Loecher Matthew Lee daniel Eun Department of Urology Lewis Katz School of MedicineTemple UniversityPhiladelphiaPAUSA

Objective:A vesicourethral anastomotic leak(VUAL)is a known complication following robotic-assisted radical *** natural history of a VUAL has been well described and is frequently managed with prolonged *** increasing emphasis on patient reported outcomes,catheter duration and VUAL are associated with significant short-term quality of life *** aimed to present a case series of our robotic early post-prostatectomy anastomotic repair technique,defined as revision within 6 weeks from index ***:A single institution prospective database identified eleven patients with a VUAL from July 2016 to October 2022 who underwent robotic early post-prostatectomy anastomotic repair by a single *** were diagnosed with a VUAL on pre-operative CT urogram or CT/fluoroscopic *** primary outcome was resolution of the anastomotic leak,defined as no contrast extravasation on post-operative *** outcomes included post-repair catheter duration and continence on the last follow-up defined as pad(s)per ***:The mean time to intervention after robotic-assisted radical prostatectomy was 21 *** of the eleven(72.7%)patients had no evidence of extravasation on postrepair *** range from intervention to first cystogram was 7e20 *** median catheter duration for those with successful intervention was 10 *** median catheter duration for those with the leak on initial post-operative cystogram was 20 *** a mean follow-up time of 25 months,eight(72.7%)patients reported using no pads per day,and three(27.3%)patients reported one pad per ***:Management of a VUAL has traditionally relied on prolonged catheter drainage and the tincture of *** the role of robotic reconstruction has been shown to be a viable modality for management of bladder neck contracture,it is important to reconsider prior dogmas of urologic *** case series suggests that an early repair is saf

关键词： Minimallyinvasive surgery Vesicourethral anastomotic leak Robotic-assisted laparoscopic reconstruction

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Prognosis value of heat-shock proteins in esophageal and esophagogastric cancer:A systematic review and meta-analysis

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1578-1595页

作者： Eric Toshiyuki Nakamura Amanda Park Marina Alessandra Pereira daniel Kikawa Francisco Tustumi Department of Gastroenterology Instituto do CâncerHospital das Clínicas da Universidade de São PauloFaculdade de MedicinaUniversidade de São PauloSão Paulo 01246000Brazil Department of Scientific Initiation Universidade Mogi das CruzesSão Paulo 08780911Brazil Department of Evidence-Based Medicine Centro Universitário LusíadaCentre for Evidence-Based MedicineCentro Universitário Lusíada(UNILUS)SantosBrazil Department of Surgery Hospital Israelita Albert EinsteinSão Paulo 05652900Brazil

BACKGROUND Heat shock proteins(HSPs)are molecular chaperones that play an important role in cellular protection against stress events and have been reported to be overex-pressed in many *** prognostic significance of HSPs and their regulatory factors,such as heat shock factor 1(HSF1)and CHIP,are poorly *** To investigate the relationship between HSP expression and prognosis in esophageal and esophagogastric *** A systematic review was conducted in accordance with PRISMA recommend-ations(PROSPERO:CRD42022370653),on Embase,PubMed,Cochrane,and ***,case-control,and cross-sectional studies of patients with eso-phagus or esophagogastric cancer were ***-positive patients were compared with HSP-negative,and the endpoints analyzed were lymph node metastasis,tumor depth,distant metastasis,and overall survival(OS).HSPs were stratified according to the HSP family,and the summary risk difference(RD)was calculated using a random-effect *** The final selection comprised 27 studies,including esophageal squamous cell carcinoma(21),esophagogastric adenocarcinoma(5),and mixed neoplasms(1).The pooled sample size was 3465 ***40 and 60 were associated with a higher 3-year OS[HSP40:RD=0.22;95%confidence interval(CI):0.09-0.35;HSP60:RD=0.33;95%CI:0.17-0.50],while HSF1 was associated with a poor 3-year OS(RD=-0.22;95%CI:-0.32 to-0.12).The other HSP families were not associated with long-term ***1 was associated with a higher probability of lymph node metastasis(RD=-0.16;95%CI:-0.29 to-0.04).HSP40 was associated with a lower probability of lymph node dissemination(RD=0.18;95%CI:0.03-0.33).The expression of other HSP families was not significantly related to tumor depth and lymph node or distant *** The expression levels of certain families of HSP,such as HSP40 and 60 and HSF1,are associated with long-term survival and lymph node dissemination in patients with esophageal and esophagogastric cancer.

关键词： Heat-shock proteins Heat-shock response Prognosis Esophageal neoplasms Meta-analysis

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Pancreatic surgery and tertiary pancreatitis services warrant provision for support from a specialist diabetes team

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World Journal of Diabetes 2024年第4期15卷 598-605页

作者： Vasileios K Mavroeidis Jennifer Knapton Francesca Saffioti daniel L Morganstein Department of HPB Surgery Bristol Royal InfirmaryUniversity Hospitals Bristol and Weston NHS Foundation TrustBristol BS28HWUnited Kingdom Department of Gastrointestinal Surgery Southmead HospitalNorth Bristol NHS TrustBristol BS105NBUnited Kingdom Department of Academic Surgery Royal Marsden NHS Foundation TrustLondon SW36JJUnited Kingdom Department of Gastroenterology and Hepatology Oxford University Hospitals NHS Foundation TrustOxford OX39DUUnited Kingdom UCL Institute for Liver and Digestive Health University College LondonLondon NW32PFUnited Kingdom Department of Endocrinology Chelsea and Westminster Hospital NHS Foundation TrustLondon SW109NHUnited Kingdom Department of Gastrointestinal Unit Royal Marsden NHS Foundation TrustLondon SW36JJUnited Kingdom

Pancreatic surgery units undertake several complex operations,albeit with consi-derable morbidity and mortality,as is the case for the management of complicated acute pancreatitis or chronic *** centralisation of pancreatic surgery services,with the development of designated large-volume centres,has contribu-ted to significantly improved *** this editorial,we discuss the complex associations between diabetes mellitus(DM)and pancreatic/periampullary disease in the context of pancreatic surgery and overall management of complex pancreatitis,highlighting the consequential needs and the indispensable role of specialist diabetes teams in support of tertiary pancreatic *** 3c pan-creatogenic DM,refers to DM developing in the setting of exocrine pancreatic disease,and its identification and management can be challenging,while the glycaemic control of such patients may affect their course of treatment and *** preoperative diabetes assessment is warranted to aid identification of patients who are likely to need commencement or escalation of glucose lowering therapy in the postoperative *** incidence of new onset diabetes after pancreatic resection is widely variable in the literature,and depends on the type and extent of pancreatic resection,as is the case with pancreatic parenchymal loss in the context of severe *** involvement of a specialist diabetes team is essential to ensure a holistic *** the current era,large volume pancreatic surgery services commonly abide by the principles of enhanced recovery after surgery,with inclusion of provisions for optimisation of the perioperative glycaemic control,to improve *** various guidelines are available to aid perioperative management of DM,auditing and quality improvement platforms have highlighted deficiencies in the perioperative management of diabetic patients and areas of required *** need for perioperative support of diabetic

关键词： Pancreatectomy Pancreatoduodenectomy Whipple’s Pancreatitis Diabetes specialist Type 3c pancreatogenic diabetes mellitus

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The Emerging Big Data Ecosystem and Digital Transformation of Poverty Governance in China

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Social Sciences in China 2024年第2期45卷 152-183页

作者： Wang Zhongyuan Su Yun Woo daniel Kübler Fudan Institute for Advanced Study in Social Sciences MOE Laboratory for National Development and Intelligent GovernanceFudan UniversityChina Department of Political Science University of TwenteNetherlands Department of Political Science University of ZurichSwitzerland

Big data technology has become increasingly prevalent in facilitating the delivery of government services and public goods in China and *** article seeks to examine how big data can be leveraged in poverty governance in rural China,and what the political implications *** phenomenon of big data-driven welfare governance is particularly salient considering the broader context of governmental digital transformation,both within China and *** research sheds light on how big data usage functions in poverty alleviation,highlighting general motivations and developments in Chinese data-centric welfare *** importantly,this article introduces the novel concept of"digital cybernetic capacity"to examine public sector modernization as big data transforms the landscape of welfare delivery and *** delving into the intersection between technology and social welfare,we explicate how the use of big data in social welfare policies can go beyond merely improving information capacity to redefine state *** article argues that such a new governance ecosystem,driven as it is by data technologies,not only provides insights about the transformative resilience of Chinese governance but also opens a new theoretical frontier for research into other countries.

关键词： big data ecosystem targeted poverty alleviation(TPA) social welfare state capacity China

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Alternating current heating techniques for lithium-ion batteries in electric vehicles:Recent advances and perspectives

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Journal of Energy Chemistry 2024年第9期96卷 679-697页

作者： Xinrong Huang Jinhao Meng Wei Jiang Wenjie Liu Kailong Liu Yipu Zhang daniel-Ioan Stroe Remus Teodorescu School of Energy and Electrical Engineering Chang’an UniversityXi’an 710018ShaanxiChina School of Electrical Engineering Xi’an Jiaotong UniversityXi’an 710049ShaanxiChina School of Highway Chang’an UniversityXi’an 710018ShaanxiChina School of Automation Northwestern Polytechnical UniversityXi’an 710072ShaanxiChina School of Control Science and Engineering Shandong UniversityJinan 250100ShandongChina Department of Energy Aalborg UniversityAalborg 9220Denmark

The significant decrease in battery performance at low temperatures is one of the critical challenges that electric vehicles(EVs)face,thereby affecting the penetration rate in cold *** current(AC)heating has attracted widespread attention due to its low energy consumption and uniform heating *** paper introduces the recent advances in AC heating from the perspective of practical EV ***,the performance degradation of EVs in low-temperature environments is introduced *** concept of AC heating and its research methods are ***,the effects of various AC heating methods on battery heating performance are *** on existing studies,the main factors that affect AC heating performance are ***,various heating circuits based on EVs are categorized,and their cost,size,complexity,efficiency,reliability,and heating rate are elaborated and *** evolution of AC heaters is presented,and the heaters used in brand vehicles are sorted ***,the perspectives and challenges of AC heating are *** paper can guide the selection of heater implementation methods and the optimization of heating effects for future EV applications.

关键词： Lithium-ion battery Low temperature Alternating current heating Heater Electric vehicle

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The circuitry landscape of perovskite solar cells:An in-depth analysis

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Journal of Energy Chemistry 2024年第7期94卷 393-413页

作者： Siddhi Vinayak Pandey daniel Prochowicz Apurba Mahapatra Saravanan Pandiaraj Abdullah N.Alodhayb Seckin Akin Pankaj Yadav Department of Solar Energy School of Energy TechnologyPandit Deendayal Energy UniversityGandhinagar 382007GujaratIndia Department of Physical Chemistry Polish Academy of SciencesKasprzaka 44/5201-224 WarsawPoland Department of Self-Development Skills King Saud UniversityRiyadh 11451Saudi Arabia Department of Physics and Astronomy College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia Department of Metallurgical and Materials Engineering Necmettin Erbakan University42060 KonyaTurkey Department of Physics School of Energy TechnologyPandit Deendayal Energy UniversityGandhinagar 382007GujaratIndia

The extensive research and development in perovskite solar cells (PSCs) have rekindled the hopes of converting solar energy into *** elusive understanding of underlying mechanisms is required for the development of efficient *** the years,Impedance Spectroscopy (IS) characterization,along with complementary techniques,has proven to be an effective way to understand and analyze the charge transport and recombination at interface and bulk of *** IS of PSCs have been analyzed,interpreted,and improvised continuously,revealing intricate details about the ***,there is a lack of centralized source of these details,which make it tougher to account for the generalized approach to understand the device *** present work is focused on compiling the research done on various PSC device architectures via IS to construct a comprehensive foundation of information on impedance plots,equivalent circuits,and associated processes.

关键词： Impedance Spectroscopy Perovskite solar cells Equivalent Circuits

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Efficiency and effectiveness of systems for the treatment of domestic wastewater based on subsurface flow constructed wetlands in Jarabacoa, Dominican Republic

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Water Science and Engineering 2024年第2期17卷 118-128页

作者： Yvelisse Pérez Enmanuel Vargas daniel Garcia-Cortes William Hernandez Humberto Checo Ulises Jauregui-Haza Area de Ciencias Basicas y Ambientales Instituto Tecnologico de Santo Domingo(INTEC)Avenida de Los Proceres 49Los Jardines del NorteSanto Domingo 10602Dominican Republic Ministry of Environment and Natural Resources Calle Cayetano Germosen esq.Ave.LuperonEl PedregalSanto Domingo 11107Dominican Republic Plan Yaque Calle Estela Geraldino 14 AltosJarabacoa 41000Dominican Republic Institute of Technologies and Applied Sciences University of HavanaHavana 10400Cuba

Constructed wetlands(CwW)are well known nature-based systems for water *** study evaluated the efficiency and effectiveness of seven domestic wastewater treatment systems based on horizontal flow CWs in Jarabacoa,the Dominican *** results showed that the CWs were efficient in reducing the degree of contamination of wastewater to levels below the Dominican wastewater discharge standards for parameters such as the 5-day biochemical oxygen demand(BOD5)and chemical oxygen demand,but not for the removal of phosphorus and fecal *** addition,a horizontal flow subsurface wetland in the peri-urban area El Dorado was evaluated in terms of the performance of wastewater treatment in tropical climatic *** concentrations of heavy metals,such as zinc,copper,chromium,and iron,were found to decrease in the effluent of the wetland,and the concentrations for nickel and manganese tended to *** levels of heavy metals in the effluent were lower than the limit values of the Dominican wastewater discharge *** construction cost of these facilities was around 200 USD per population equivalent,similar to the cost in other countries in the same *** study suggested some solutions to the improved performance of CWs:selection of a microbial flora that guarantees the reduction of nitrates and nitrites to molecular nitrogen,use of endemic plants that bioaccumulate heavy metals,combination of constructed wetlands with filtration on activated carbon,and inclusion of water purification processes that allow to evaluate the reuse of treated water.

关键词： Domestic wastewater Constructed wetland BOD COD Pathogens Heavy metals

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RPLP0/TBP are the most stable reference genes for human dental pulp stem cells under osteogenic differentiation

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World Journal of Stem Cells 2024年第6期16卷 656-669页

作者： daniel B Ferreira Leticia M Gasparoni Cristiane F Bronzeri Katiucia B S Paiva Laboratory of Extracellular Matrix Biology and Cellular Interaction Department of AnatomyInstitute of Biomedical SciencesUniversity of São PauloSão Paulo 05508-000São PauloBrazil

BACKGROUND Validation of the reference gene(RG)stability during experimental analyses is essential for correct quantitative real-time polymerase chain reaction(RT-qPCR)data ***,in an unreliable way,several studies use genes involved in essential cellular functions[glyceraldehyde-3-phosphate dehydro-genase(GAPDH),18S rRNA,andβ-actin]without paying attention to whether they are suitable for such experimental conditions or the reason for choosing such ***,such studies use only one gene when Minimum Information for Publication of Quantitative Real-Time PCR Experiments guidelines recom-mend two or more *** impacts the credibility of these studies and causes dis-tortions in the gene expression *** tissue engineering,the accuracy of gene expression drives the best experimental or therapeutical *** cultivated DPSCs under two conditions:Undifferentiated and osteogenic dif-ferentiation,both for 35 *** evaluated the gene expression of 10 candidates for RGs[ribosomal protein,large,P0(RPLP0),TATA-binding protein(TBP),GAPDH,actin beta(ACTB),tubulin(TUB),aminolevulinic acid synthase 1(ALAS1),tyro-sine 3-monooxygenase/tryptophan 5-monooxygenase activation protein,zeta(YWHAZ),eukaryotic translational elongation factor 1 alpha(EF1a),succinate dehydrogenase complex,subunit A,flavoprotein(SDHA),and beta-2-micro-globulin(B2M)]every 7 d(1,7,14,21,28,and 35 d)by *** data were analysed by the four main algorithms,ΔCt method,geNorm,NormFinder,and BestKeeper and ranked by the RefFinder *** subdivided the samples into eight *** All of the data sets from clonogenic and osteogenic samples were analysed using the RefFinder *** final ranking showed RPLP0/TBP as the two most stable RGs and TUB/B2M as the two least stable *** theΔCt method or NormFinder analysis showed TBP/RPLP0 as the two most stable ***,geNorm analysis showed RPLP0/EF1αin the first *** algorithms’two least stab

关键词： Dental pulp stem cells Reference gene Housekeeping gene Endogenous gene Osteogenic differentiation RefFinder

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Outcomes and variables that impact pneumatic retinopexies

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 564-569页

作者： Maria V.Castanos daniel Vail Oscar Otero-Marquez Yash Shah Avnish Deobhakta New York Eye and Ear Infirmary of Mount Sinai New York 10003New YorkUSA

●AIM:To evaluate the efficacy of pneumatic retinopexy(PR)in patients undergoing PR as primary treatment for rhegmatogenous retinal detachment(RRD)and analyze the factors associated with success and failure in the studied population.●METHODS:A retrospective chart review was done of patients with RRD treated with PR as primary management method treated at New York Eye and Ear Infirmary of Mount Sinai between January 2017 and December *** outcome measured success or failure of *** outcome measured best corrected visual acuity(BCVA)after PR.A separate risk analysis was done to identify and stratify risks associated with success and failure of PR.●RESULTS:A total of 179 eyes from 179 patients were included for final *** 83 patients(46.37%)achieved anatomical reattachment of the retina after primary PR with no need for additional *** 96 patients(53.63%)had a failed primary PR and required a PPV and 6 of them required pars plana vitrectomy(PPV)with scleral buckle(SB).In total,19 cases(10.61%)were done as temporizing pneumatics,18(94.74%)underwent PPV,and 1(5.26%)did not require further *** visual acuities at postoperative month 1(POM1)for patients who underwent primary PR successfully and for those that underwent PPV after,were 0.58(20/80)and 1.03(20/200)*** who met Pneumatic Retinopexy Versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial(PIVOT)criteria had a statistically significant decreased risk of primary PR failing(hazard ratio 0.29,P=0.00).Majority of missed or new breaks were found superotemporally.●CONCLUSION:PR is a good treatment option for treating RRDs in patients that meet PIVOT criteria and can be conducted as a temporizing *** criteria and fovea on status decrease the risk of PR failure.

关键词： retina pneumatic retinopexy rhegmatogenous retinal detachment

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Coffee Leaf Rust(Hemileia vastatrix)Disease in Coffee Plants and Perspectives by the Disease Control

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Phyton-International Journal of Experimental Botany 2024年第5期93卷 923-949页

作者： Alexis Salazar-Navarro Victor Ruiz-Valdiviezo Jose Joya-Dávila daniel Gonzalez-Mendoza Instituto de Ciencias Agrícolas de la Universidad Autónoma de Baja California(ICA-UABC) Nuevo LeónBaja California21705México Laboratorio de Biología Molecular del Instituto Tecnológico Nacional de Tuxtla Gutierrez(TecNM) Tuxtla GutierrezChiapas29050México Facultad de Ciencias Agronómicas Campus V.Universidad Autónoma de Chiapas(UNACH) VillafloresChiapas30470México

Coffee Leaf Rust(CLR)is caused by Hemileia vastatrix in Coffea *** is one of the most dangerous phytopathogens for coffee plantations in terms of coffee productivity and coffee cup *** this review,we resume the problem of CLR in Mexico and the pathogenesis of *** review abord plant-pathogen interactions which lead a compatible or incompatible interactions and result in CLR disease or resistance,*** review abord Coffea *** response pathways involved in *** ***,current measures to control *** proliferation and germination were aborded focused on phytosanitary actions,and biological and chemical ***,new trendlines to reduce the impact of CLR as nanoparticles and nanotechnology were analyzed.

关键词： Coffee leaf rust Coffea arabica pathogenesis nanoparticles biological control

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