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Expert consensus on difficult airway assessment

Hepatobiliary Surgery and Nutrition 2023年第4期12卷 545-566页

作者： Ming Xia Wuhua Ma Mingzhang Zuo Xiaoming Deng Fushan Xue Denise Battaglini Vivek Aggarwal Giustino Varrassi Vladimir Cerny Ida Di Giacinto Rita Cataldo Daqing Ma Toru Yamamoto Martina Rekatsina Alessandro De Cassai Andrea Carsetti Marvin G.Chang Edwin Seet daniel p.davis Michael G.Irwin Yuguang Huang Hong Jiang Department of Anesthesiology Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Anesthesiology The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhouChina Department of Anaesthesiology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical ScienceBeijingChina Department of Anesthesiology Plastic Surgery HospitalCAMS and PUMCBeijingChina Department of Anesthesiology Beijing Friendship HospitalCapital Medical UniversityBeijingChina Anesthesia and Intensive Care San Martino Policlinico HospitalIRCCS for Oncology and NeuroscienceGenoaItaly Department of Conservative Dentistry&Endodontics Jamia Millia IslamiaNew DelhiIndia paolo procacci Foundation RomaItaly Department of Anaesthesiology and Intensive Care Medicine University Hospital Hradec KraloveHradec KraloveCzech Republic Unit of Anesthesia and Intensive Care Mazzoni HospitalAscoli PicenoItaly Unit of Anaesthesia Intensive Care and Pain ManagementDepartment of MedicineUniversitàCampus Bio-Medico of RomeRomaItaly Division of Anaesthetics Pain Medicine&Intensive CareDepartment of Surgery&CancerFaculty of MedicineImperial College Londonand Chelsea and Westminster HospitalLondonUK Division of Dental Anesthesiology Graduate School of Medicine and Dental SciencesNiigata UniversityNiigataJapan Department of Anaesthesiology National and Kapodistrian University of AthensAthensGreece Institute of Anesthesia and Intensive Care Unit University Hospital of PaduaPaduaItaly Department of Biomedical Sciences and public Health UniversitàPolitecnica delle MarcheAnconaItaly Anesthesia and Intensive Care Unit Azienda Ospedaliero Universitaria delle MarcheAnconaItaly Department of Anesthesia Critical Careand Pain MedicineMassachusetts General HospitalBostonMAUSA Lee Kong Chian School of Medicine Nanyang Technological UniversitySingaporeSingapore Department of Anaesthesia Yong Loo Lin School of Medic

Background:Identifying a potentially difficult airway is crucial both in anaesthesia in the operating room(OR)and non-operation room *** are no guidelines or expert consensus focused on the assessment of the difficult airway before,so this expert consensus is developed to provide guidance for airway assessment,making this process more standardized and accurate to reduce airway-related complications and improve ***:Seven members from the Airway Management Group of the Chinese Society of Anaesthesiology(CSA)met to discuss the first draft and then this was sent to 15 international experts for review,comment,and *** Grading of Recommendations,Assessment,Development and Evaluation(GRADE)is used to determine the level of evidence and grade the strength of *** recommendations were revised through a three-round Delphi survey from ***:This expert consensus provides a comprehensive approach to airway assessment based on the medical history,physical examination,comprehensive scores,imaging,and new developments including transnasal endoscopy,virtual laryngoscopy,and 3D *** addition,this consensus also reviews some new technologies currently under development such as prediction from facial images and voice information with the aim of proposing new research directions for the assessment of difficult ***:This consensus applies to anesthesiologists,critical care,and emergency physicians refining the preoperative airway assessment and preparing an appropriate intubation strategy for patients with a potentially difficult airway.

关键词： Expert consensus difficult airway airway management

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异氟烷复合caspase抑制剂减轻局部脑缺血损伤

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国外医学（麻醉学与复苏分册） 2004年第4期25卷 253-256页

作者： Satoki Inoue John C.Drummond daniel p.davis daniel J.Cole piyush M.patel 马正良(译) 曾因明(审) Department of Anesthesiology Veterans Affairs Medical Center and University of CaliforniaSan Diego Department of Anesthesiology University of CaliforniaSan Diego Department of Emergency Medicine University of CaliforniaSan Diego Department of Anesthesiology The Mayo ClinicScottsdaleArizona 不详

背景:近来研究提示异氟烷的神经保护作用不是持续的.由细胞凋亡介导的神经元的延迟性死亡可导致梗死面积的逐渐增加.这些资料提示异氟醚可能不能抑制延迟性神经元死亡.除了异氟烷外,caspase抑制剂的神经细胞凋亡预防作用可以提供神经保... 详细信息

背景:近来研究提示异氟烷的神经保护作用不是持续的.由细胞凋亡介导的神经元的延迟性死亡可导致梗死面积的逐渐增加.这些资料提示异氟醚可能不能抑制延迟性神经元死亡.除了异氟烷外,caspase抑制剂的神经细胞凋亡预防作用可以提供神经保护作用.本研究的开展是决定在非特异性的caspase抑制剂z-VAD-fmk存在下异氟烷的神经保护作用是否更持久。

关键词：异氟烷复合Caspase抑制剂局部脑缺血损伤细胞凋亡介导神经元

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Estimating geographic variation of infection fatality ratios during epidemics

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Infectious Disease Modelling 2024年第2期9卷 634-643页

作者： Joshua Ladau Eoin L.Brodie Nicola Falco Ishan Bansal Elijah B.Hoffman Marcin p.Joachimiak Ana M.Mora Angelica M.Walker Haruko M.Wainwright Yulun Wu Mirko pavicic daniel Jacobson Matthias Hess James B.Brown Katrina Abuabara Departments of Computational precision Health and Dermatology University of CaliforniaSan FranciscoCA94115USA Arva Intelligence Inc.Salt Lake CityUT84101USA Computational Biosciences Group Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Earth and Environmental Sciences Area Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Graduate Group in Biostatistics University of CaliforniaBerkeleyCA94720USA Biosystems Data Science Environmental Genomics and Systems BiologyLawrence Berkeley National LaboratoryBerkeleyCA94720USA Center for Environmental Research and Community Health(CERCH) School of Public HealthUniversity of CaliforniaBerkeleyCA94720USA Bredesen Center for Interdisciplinary Research and Graduate Education University of TennesseeKnoxvilleTN37996USA Department of Nuclear Science and Engineering Massachusetts Institute of TechnologyBostonMA02139USA Biosciences Oak Ridge National LaboratoryOak RidgeTN37830USA University of California DavisCA95616USA Statistics Department University of CaliforniaBerkeleyCA94720USA Division of Epidemiology and Biostatistics University of California Berkeley School of Public Health2121 Berkeley WayBerkeleyCA94720USA

Objectives We aim to estimate geographic variability in total numbers of infections and infection fatality ratios(IFR;the number of deaths caused by an infection per 1,000 infected people)when the availability and quality of data on disease burden are limited during an *** We develop a noncentral hypergeometric framework that accounts for differential probabilities of positive tests and reflects the fact that symptomatic people are more likely to seek *** demonstrate the robustness,accuracy,and precision of this framework,and apply it to the United States(U.S.)COVID-19 pandemic to estimate county-level SARS-CoV-2 *** The estimators for the numbers of infections and IFRs showed high accuracy and precision;for instance,when applied to simulated validation data sets,across counties,pearson correlation coefficients between estimator means and true values were 0.996 and 0.928,respectively,and they showed strong robustness to model *** the county-level estimators to the real,unsimulated COVID-19 data spanning April 1,2020 to September 30,2020 from across the U.S.,we found that IFRs varied from 0 to 44.69,with a standard deviation of 3.55 and a median of *** The proposed estimation framework can be used to identify geographic variation in IFRs across settings.

关键词： Infection fatality ratio Infection fatality rate Noncentral hypergeometric distribution COVID-19 SARS-CoV-2

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A pentaploid-based linkage map of the ancestral octoploid strawberry Fragaria virginiana reveals instances of sporadic hyper-recombination

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Horticulture Research 2020年第1期7卷 1796-1810页

作者： Thomas M.davis Yilong Yang Lise L.Mahoney daniel C.Frailey Department of Agriculture Nutritionand Food SystemsUniversity of New HampshireDurhamNH 03824USA

The first high-resolution genetic linkage map of the ancestral octoploid(2n=8x=56)strawberry species,Fragaria virginiana,was constructed using segregation data obtained from a pentaploid progeny *** novel mapping population of size 178 was generated by crossing highly heterozygous *** hybrid“LB48”as a paternal parent with diploid(2n=2x=14)Fragaria vesca“Hawaii 4”.The LB48 linkage map comprises 6055 markers genotyped on the Axiom®IStraw90 strawberry SNp *** map consists of 28 linkage groups(LGs)organized into seven homoeology groups of four LGs each,and excludes a small 29th LG of undefined *** member of each homoeology group was assignable to an“A”subgenome associated with ancestral diploid Fragaria vesca,while no other subgenomes were *** an intriguing discrepancy within homoeology group VI,synteny comparisons with the previously published Fragaria×ananassa DA×MO linkage map revealed substantial *** initial map construction,examination of crossover distributions revealed that six of the total 5162(=29 chromosomes/individual×178 individuals)chromosomes making up the data set exhibited abnormally high crossover counts,ranging from 15 to 48 crossovers per chromosome,as compared with the overall mean of 0.66 crossovers per *** of these six hyper-recombinant(HypR)chromosomes occurred in a different LG and in a different *** calculated upon exclusion of the six HypR chromosomes,the canonical(i.e.,broadly representative)LB48 map had 1851 loci distributed over a total map length of 1873 cM,while their inclusion increased the number of loci by 130,and the overall map length by 91 *** of these hyper-recombinant chromosomes points to the existence of a sporadically acting mechanism that,if identified and manipulable,could be usefully harnessed for multiple purposes by geneticists and breeders.

关键词： Fragaria straw linkage

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β-funaltrexamine differentially modulates chemokine and cytokine expression in normal human astrocytes and C20 human microglial cells

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Neuroimmunology and Neuroinflammation 2020年第4期7卷 300-310页

作者： Randall L.davis Kelly McCracken daniel J.Buck Department of pharmacology/physiology Oklahoma State University Center for Health SciencesTulsaOK 74107USA

Aim: Emerging evidence implicates astrocyte/microglia dysregulation in a range of brain disorders, thereby making glial cells potential therapeutic targets. The novel anti-inflammatory actions of beta-funaltrexamine (β-FNA) are of particular interest. β-FNA is a derivative of naltrexone, and recognized as a selective, irreversible antagonist at the mu-opioid receptor (MOR). However, we discovered that β-FNA has novel anti-inflammatory actions that seem to be mediated through a MOR-independent mechanism. Thus far, we have focused on the acute effects of β-FNA on inflammatory ***: The effect of β-FNA treatment on interleukin-1β (IL-1β)-induced inflammatory signaling in normal human astrocytes (NHA) and C20 human microglial cells. Cytokine/chemokine expression was measured using ELISA, and nuclear factor-kappaB (NF-κB) p65 activation was evaluated by immunoblot. Results: IL-1β-induced interferon-γ inducible protein-10 (CXCL10) production in NHA was more sensitive to chronic (3 day) β-FNA as indicated by an approximately 3-fold lower EC50 compared to that observed in acutely treated cells. Chronic β-FNA did not affect IL-1β-induced monocyte chemoattractant protein-1 (CCL2) or IL-6 production in NHA. β-FNA inhibited phosphorylation of NF-κB p65, suggesting that the inhibitory effects may be due in part to reduced NF-κB activation. We showed for the first time that C20 human microglial cells were insensitive to the anti-inflammatory actions of acute β-FNA. Conclusion: β-FNA differentially affects inflammatory cytokine/chemokine expression in human astrocytes and microglia. These findings warrant further investigation into the novel anti-inflammatory actions of β-FNA, with a particular focus on astrocytes. These insights should contribute to the development of strategies to treat brain disorders that involve neuroinflammation.

关键词： Neuroinflammation brain opioid nuclear factor-kappaB pro-inflammatory

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皮肤病摄影的回顾和展望

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中华皮肤科杂志 2011年第10期44卷 754-755页

作者：崔勇 W.p. daniel Su Mark D.p. davis Mark R. pittelkow 张学军安徽医科大学皮肤病研究所安徽医科大学第一附属医院皮肤性病科合肥230032 Dermatology Department of Mayo Clinic Rochester Minnesota USA

医学知识最早由文字或绘画记载，皮肤病学亦是如此，已知最早被绘画记载的皮肤病是梅毒。很多著名皮肤病学家如Ferdinand Hebra（1816--1880年，Vienna皮肤病学校创立者）、Moritz Kaposi（1837—1902年，最早研究红斑狼疮、扁平苔藓等... 详细信息

医学知识最早由文字或绘画记载，皮肤病学亦是如此，已知最早被绘画记载的皮肤病是梅毒。很多著名皮肤病学家如Ferdinand Hebra（1816--1880年，Vienna皮肤病学校创立者）、Moritz Kaposi（1837—1902年，最早研究红斑狼疮、扁平苔藓等疾病，

关键词：皮肤病学摄影医学知识红斑狼疮扁平苔藓绘画

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Supertransport of excitons in atomically thin organic semiconductors at the 2D quantum limit

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Light(Science & Applications) 2020年第1期9卷 907-919页

作者： Ankur Sharma Linglong Zhang Jonathan O.Tollerud Miheng Dong Yi Zhu Robert Halbich Tobias Vogl Kun Liang Hieu T.Nguyen Fan Wang Shilpa Sanwlani Stuart K.Earl daniel Macdonald ping Koy Lam Jeffrey A.davis Yuerui Lu Research School of Electrical Energy and Materials EngineeringCollege of Engineering and Computer ScienceThe Australian National UniversityCanberraACT 2601Australia Optical Sciences Centre Swinburne University of TechnologyHawthornVIC 3122Australia ARC Centre of Excellence for Future Low-Energy Electronics Technology Australia Centre for Quantum Computation and Communication Technology Department of Quantum ScienceResearch School of Physics and EngineeringThe Australian National UniversityActonACT 2601Australia School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China Institute for Biomedical Materials and Devices(IBMD) Faculty of ScienceUniversity of Technology SydneySydneyNSW 2007Australia

Long-range and fast transport of coherent excitons is important for the development of high-speed excitonic circuits and quantum computing ***,most of these coherent excitons have only been observed in some low-dimensional semiconductors when coupled with cavities,as there are large inhomogeneous broadening and dephasing effects on the transport of excitons in their native states in ***,by confining coherent excitons at the 2D quantum limit,we first observed molecular aggregation-enabled‘supertransport’of excitons in atomically thin two-dimensional(2D)organic semiconductors between coherent states,with a measured high effective exciton diffusion coefficient of ~346.9 cm^(2)/s at room *** value is one to several orders of magnitude higher than the values reported for other organic molecular aggregates and low-dimensional inorganic *** coupling to any optical cavities,the monolayer pentacene sample,a very clean 2D quantum system(~1.2 nm thick)with high crystallinity(J-type aggregation)and minimal interfacial states,showed superradiant emission from Frenkel excitons,which was experimentally confirmed by the temperature-dependent photoluminescence(pL)emission,highly enhanced radiative decay rate,significantly narrowed pL peak width and strongly directional in-plane *** coherence in monolayer pentacene samples was observed to be delocalised over~135 molecules,which is significantly larger than the values(a few molecules)observed for other organic thin *** addition,the supertransport of excitons in monolayer pentacene samples showed highly anisotropic *** results pave the way for the development of future high-speed excitonic circuits,fast OLEDs,and other optoelectronic devices.

关键词： transport quantum coherent

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Introduction:The past,present,and future of research on running barefoot and in minimal shoes

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Journal of Sport and Health Science 2014年第2期3卷 65-66,152页

作者： daniel E.Lieberman Irene S.davis Benno M.Nigg Department of Human Evolutionary Biology Harvard University Spaulding National Running Center’ Department of physical Medicine and Rehabilitation Harvard Medical School Human performance Laboratory Faculty of Kinesiology The University of Calgary

Barefoot running has been around for millions of years,and it is safe to presume that for most of that time,the practice occasioned little *** ancestors ran barefoot because they had no *** footwear was first invented during the last 40,000 years (no doubt at different times and in different places),shoes were by necessity minimal-essentially sandals and moccasins-designed to protect the sole of the foot but lacking any of the sophisticated features and materials present in modem running shoes such as elevated cushioned heels,arch supports,and toe *** of these features were invented in the 1970s,and they quickly became more popular and sophisticated as running underwent a worldwide ***,the vast majority of runners think it is normal to wear cushioned running shoes,and would never dream of running without them.

关键词： necessity shoes sophisticated doubt millions running essentially likely debate briefly

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远程皮肤病学的现状和展望

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中国皮肤性病学杂志 2011年第11期25卷 829-831页

作者：崔勇 W.p. daniel Sue Mark D.p. davis Mark R. pittelkow 张学军安徽医科大学皮肤病研究所安徽医科大学第一附属医院皮肤性病科安徽合肥230032 Dermatology Department of Mayo Clinic Rochester Minnesota USA

远程医学泛指应用远程通讯技术交换医学信息,以达到诊断、咨询、治疗和教学目的。远程放射学、远程病理学和远程皮肤病学是目前应用较为广泛的远程医学领域。文中对远程皮肤病学的发展简史、现状和可能的发展趋势进行综述。

关键词：远程皮肤病学现状展望

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pVC Formulation of Anastrepha suspensa pheromones Suitable for Field Studies

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Engineering 2021年第11期7卷 1646-1650页

作者： daniel Kuzmich Zachary A.Kawagoe Spencer S.Walse San Joaquin Valley Agricultural Sciences Center Agricultural Research ServiceUnited States Department of AgricultureParlierCA 93648USA Agricultural and Environmental Chemistry Graduate Group University of CaliforniaDavisCA 95616USA

Tephritid flies threaten the production of fruits around the *** the Americas,populations of the genus Anastrepha are monitored with trapping networks as part of pest management ***,we report the formulation of male Anastrepha suspensa(Loew)pheromones,(±)-anastrephin and(±)-epianastrephin,into a poly(vinyl chloride)(pVC)polymer-based lure ready for trap *** pVC polymer disks(100 mg)contain 10%by weight of(±)-epianastrephin and(±)-anastrephin in a naturally occurring 7:3 diastereomeric ratio,*** of the pheromones from the disks into an airstream was evaluated as a function of the abiotic environmental parameters,absolute humidity and *** data supports a diffusion-controlled mechanism of release from the matrix with first-order rate constants that decreased about ten-fold as the temperature was lowered from 30 to 15*** such,the emission of volatile pheromones from the disks is suitable to last for several weeks in the *** kinetic approach,which can be easily extended to the diffusion-controlled release of other attractants from polymeric matrices,yields laboratory predictions of the potential for environmental loss prior to conducting field bioassays.

关键词： Anastrepha Anastrephin Epianastrephin pVC lure Controlled release

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