检索结果-南通市图书馆

The price of protection:a defensive endosymbiont impairs nymph growth in the bird cherry-oat aphid,Rhopalosiphum padi

在线全文

学校读者我要写书评

暂无评论

Insect Science 2020年第1期27卷 69-85页

作者： daniel j.leyboume jorunn I.B.Bos Tracy A.Valentine Alison j.Karley Division of Plant Sciences School of Life SciencesUniversity of DundeeDundeeU K Cell and Molecular Sciences the James Hutton InstituteInvergowrieDundeeUK Ecological Sciences the James Hutton InstituteInvergowrieDundeeUK

Bacterial endosymbionts have enabled aphids to adapt to a range of stressors,but their effects in many aphid species remain to be *** bird cherry-oat aphid,Rhopalosiphum padi(linnaeus),is an important pest of cereals worldwide and has been reported to form symbiotic associations with Serratia symbiotica and Sitobion miscanthi l-type symbiont endobacteria,although the resulting aphid phenotype has not been *** study presents the first report of *** infection with the facultative bacterial endosymbiont Hamiltonella *** of *** were sampled from populations in Eastern Scotland,UK,and shown to represent seven *** genotypes based on the size of polymorphic microsatellite markers;two of these genotypes harbored *** parasitism assays,survival of ***-infected nymphs following attack by the parasitoid wasp Aphidius colemani(Viereck)was 5 fold higher than for uninfected *** genotype was a major determinant of aphid performance on two Hordeum species,a modern cultivar of barley *** and a wild relative ***,although aphids infected with *** showed 16%lower nymph mass gain on the partially resistant wild relative compared with uninfected *** findings suggest that deploying resistance traits in barley will favor the fittest *** genotypes,but symbiontinfected individuals will be favored when parasitoids are abundant,although these aphids will not achieve optimal performance on a poor quality host plant.

关键词： cereal aphid Hamiltonella defensa Hordeum spontaneum Hordeum vulgare symbiosis

The N-terminus of COX-1 and its effect on cyclooxygenase-1 catalytic activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

journal of Genetics and Genomics 2010年第2期37卷 117-123页

作者： Sean Phipps Michael j. Turner daniel l. Simmons Chemistry and Biochemistry Department Brigham Young University

Cyclooxygenases are encoded by COX-1 and COX-2. They share over sixty percent sequence identity in human and are similar to each other in their crystallographic structures. One major difference in the primary structure of these two isozymes is the presence of eight amino acids in the amino-terminal region of COX-1 that are not present in COX-2. The function of this amino acid sequence is unknown. In this study, a human COX-1 mutant （Δ7aa） with this sequence removed was studied in parallel with COX-1. Signal peptide cleavage, N-linked glycosylation, protein expression, distribution and dimerization were not affected by the mutation. The mutant was enzymati-cally active and showed the same sensitivity toward aspirin. The KM for the enzyme remained the same as COX-1. However, the Vmax of the COX-1 mutant decreased by 3.3-fold. We conclude that the COX-1 specific amino-terminal sequence has a subtle but detectable effect on COX-1 catalysis.

关键词： COX-1 COX-2 dimerization glycosylation aspirin KM Vmax

Human-Swarm-Teaming Transparency and Trust Architecture

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA journal of Automatica Sinica 2021年第7期8卷 1281-1295页

作者： Adam j.Hepworth daniel P.Baxter Aya Hussein Kate j.Yaxley Essam Debie Hussein A.Abbass the School of Engineering and Information Technology University of New South WalesCanberraNew South Wales 2612Australia

Transparency is a widely used but poorly defined term within the explainable artificial intelligence *** is due,in part,to the lack of an agreed definition and the overlap between the connected—sometimes used synonymously—concepts of interpretability and *** assert that transparency is the overarching concept,with the tenets of interpretability,explainability,and predictability *** draw on a portfolio of definitions for each of these distinct concepts to propose a human-swarm-teaming transparency and trust architecture(HST3-Architecture).The architecture reinforces transparency as a key contributor towards situation awareness,and consequently as an enabler for effective trustworthy human-swarm teaming(HST).

关键词： Artificial intelligence explainability human-swarm teaming(HST) interpretability predictability swarm shepherding transparency.

Improved speciation of dissolved organic nitrogen in natural waters: amide hydrolysis with fluorescence derivatization

在线全文

学校读者我要写书评

暂无评论

journal of Environmental Sciences 2008年第10期20卷 1273-1280页

作者： Ryan l.Fimmen Tamara D.Trouts daniel D.Richter jr. Dharni Vasudevan School of Earth Sciences The Ohio State University 125 S.Oval MallColumbus OH 43210 USA.Nicholas School of the Environment and Earth Sciences Duke University Durham NC 27708 USA School of Earth Sciences The Ohio State University 125 S.Oval MallColumbus OH 43210 USA Nicholas School of the Environment and Earth Sciences Duke UniversityDurham NC 27708 USA. Nicholas School of the Environment and Earth Sciences Duke UniversityDurham NC 27708 USA.Department of Chemistry Bowdoin CollegeBrunswick ME 04011 USA

The objective of this study was to improve primary-amine nitrogen (1°-N) quantification in dissolved organic matter (DOM) originating from natural waters where inorganic forms of N, which may cause analytical interference, are commonly encountered. Efforts were targeted at elucidating organic-N structural criteria influencing the response of organic amines to known colorimetric and fluorescent reagents and exploring the use of divalent metal-assisted amide hydrolysis in combination with fluorescence analyse...

关键词： dissolved organic matter/nitrogen (DOM/DON) o-phthaldialdehyde fluorescamine ninhydrin amino acids amide hydrolysis peptides

Increased CD4/CD8 lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer:A prospective pilot study

在线全文

学校读者我要写书评

暂无评论

World journal of Gastrointestinal Oncology 2023年第2期15卷 303-317页

作者： daniel Skubleny Andrea lin Saurabh Garg Ross Mclean Michael McCall Sunita Ghosh jennifer l Spratlin daniel Schiller Gina Rayat Department of Surgery University of AlbertaEdmonton T6G 2R3ABCanada Department of Surgery University of AlbertaEdmonton T6G 2R3AlbertaCanada Department of laboratory Medicine and Pathology University of AlbertaEdmonton T6G 2R3AlbertaCanada Department of Oncology University of AlbertaEdmonton T6G 2R3AlbertaCanada Department of Oncology Cross Cancer InstituteUniversity of AlbertaEdmonton T5G 1Z2ABCanada

BACKGROUND Despite optimal neoadjuvant chemotherapy only 40%of gastric cancer tumours achieve complete or partial treatment *** the absence of treatment response,neoadjuvant chemotherapy in gastric cancer contributes to adverse events without additional survival benefit compared to adjuvant treatment or surgery *** strategies and methods are required to optimize the allocation of existing treatment regimens such as FlOT chemotherapy(5-Fluorouracil,leucovorin,Oxaliplatin and Docetaxel).Predictive biomarkers detected using immunohistochemistry(IHC)methods may provide useful data regarding treatment *** To investigate the utility of CD4,CD8,Galectin-3 and E-cadherin in predicting neoadjuvant FlOT chemotherapy tumour response in gastric *** Forty-three adult patients with gastric adenocarcinoma,of which 18 underwent neoadjuvant chemotherapy,were included in a prospective clinical *** biopsies were obtained from gastric cancer and normal adjacent gastric *** in expression of Galectin-3,Ecadherin,CD4^(+)and CD8^(+)molecules between tumours with and without treatment response to neoadjuvant chemotherapy were assessed with *** response was graded by clinical pathologists using the Tumour Regression Score according to the College of American Pathologists *** response was defined as complete or near complete tumour response,whereas partial or poor/no response was defined as *** IHC images were annotated and quantitatively assessed using QuPath *** expression between responsive and incomplete response tumours was assessed using a two-sided Wilcoxon *** expression was also compared between normal and cancer tissue and between 15 paired tumour samples before and after *** performed a preliminary multivariate analysis and power analysis to guide future *** analyses were completed using R *** The ratio betw

关键词： CD4 CD8 Galectin-3 Neoadjuvant chemotherapy Treatment response Gastric cancer

The growing threat of non-alcoholic fatty liver disease-related hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2022年第5期11卷 735-737页

作者： Margaret l.P.Teng Kai En Chan Darren j.H.Tan daniel Q.Huang Division of Gastroenterology and Hepatology Department of MedicineNational University Health SystemSingaporeSingapore Yong loo lin School of Medicine National University of SingaporeSingaporeSingapore

Non-alcoholic fatty liver disease(NAFlD)is the fastest growing cause of hepatocellular carcinoma(HCC)worldwide(1).It is anticipated that the burden of NAFlD-related HCC will continue to increase in tandem with the global obesity epidemic(2,3).This has become a global issue of concern,as liver cancer is associated with significant morbidity and mortality,and is currently the third leading cause of cancer death(4).

关键词： hepatocellular NAFlD liver

Recovery of valuable metals from waste cables by employing mechanical processing followed by spouted bed elutriation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2019年第4期17卷 74-80页

作者： Eduardo H. Tanabe Roger M. Silva Daliomar l. Oliveira junior daniel A. Bertuol Environmental Processes laboratory (lAPAM) Chemical Engineering Department Federal University of Santa Maria - UFSM Santa Maria RS Brazil

Cables and wires, which are essential parts of equipment for the transmission of both information and electricity, contain valuable materials including copper (Cu) and aluminum (Al). This experimental work evaluates the use of mechanical processing (grinding and sieving), followed by spouted bed elutriation, for separation of the valuable materials (steel-coated copper, copper, and aluminum) present in waste coaxial and internet cables. A recovery efficiency of approximately 90% was achieved for the steel-coated copper in coaxial cables. For in ternet cables, the copper recovery efficiency was approximately 87%. These findings dem on strate that it is possible to separate, recover, and recycle the valuable materials (metals) present in waste cables using simple, low-cost, and efficient mechanical processing followed by spouted bed elutriation.

关键词： Waste cable Elutriation Copper Recycling Mechanical process

Using tickler chains to promote more environmentally benign trawls in an Australian penaeid fishery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aquaculture and Fisheries 2023年第3期8卷 316-322页

作者： Matt.K.Broadhurst daniel j.Tolhurst NSW Department of Primary Industries Fisheries Conservation Technology UnitNational Marine Science CentreSouthern Cross University2 Bay DriveCoffs HarbourNSW2450Australia Marine and Estuarine Ecology Unit School of Biological SciencesUniversity of QueenslandBrisbaneQLD4072Australia The Roslin Institute and Royal(Dick)School of Veterinary Studies University of EdinburghEaster BushMidlothianEH259RGUnited Kingdom

There has been an increasing emphasis on reducing the environmental impacts of penaeid trawls by modifying their anterior *** one Australian estuary,this approach has culminated in a new generic trawl comprising a slightly smaller mesh size,and steeper and shorter side panels than traditional trawls,combined with a top panel extending forwards of the bottom panel(termed‘lead-ahead’)and no headline *** study sought to investigate if an additional simple,cumulative modification(tickler chain)might help promote adoption of the new trawl,via improved penaeid *** volunteer fishers towing pairs of either the traditional or new trawls in double rigs were asked if an observer could accompany fishing trips,and alternately attach a light tickler chain(~3 kg)anterior to the ground gear of one *** of the trawl design,the tickler chains significantly increased the catch weights of penaeids,but relatively more so in the new trawls(by 1.11×vs 1.08×).The tickler chains also significantly increased the number and weight of total bycatch in the traditional trawls(by up to 1.22×),but not in the new trawls-although there were variable species-specific *** terms of total effects,the data support using tickler chains to increase the efficiency of the new trawls and their cumulative benefits,and could be promoted to facilitate broader inter-and intra-fleet adoption.

关键词： Ground-gear Penaeid Selectivity Tickler chain Trawling

Deadly oasis:Recurrent annihilation of Cretaceous desert bryophyte colonies;the role of solar,climate and lithospheric forcing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2021年第1期12卷 1-12页

作者： juan Pedro Rodríguez-lópeza Eduardo Barrón daniel Peyrot Gary B.Hughes Department of Geology.Faculty of Science.United Arab Emirates University.50009.Al Ain Abu DhabiUnited Arab Emirates Instituto Geológico y Minero de Espana(IGME) Ríos Rosas 23E-28003MadridSpain School of Earth and Environment University of Western Australia.6101CrawleyWestern AustraliaAustralia Centre for Energy Geosciences University of Western Australia.6101CrawleyWestern AustraliaAustralia Physics Department University of CaliforniaSanta BarbaraCA93106USA

Many oases(wet interdunes)are sedimentary systems characterized by high-frequency water-level oscillations,marked changes in salinity and intense biological activity at their *** are considered to be one of the most challenging environments on Earth for ecosystem *** dynamic,depositional settings are usually unfavourable for fossilization and subsequent preservation of vegetal *** paper describes bryophyte(liverwort)assemblages occurring in three successive horizons interpreted to represent(i)recurrent early successional phases of biological soil crust colonization of wet interdune margins or(ii)exceptional preservation of floating or riparian liverworts in oasis pond waters associated with a progressive fall of the interdune water *** record of in situ colonization surfaces characterized by delicate(***-free)three-dimensional structures represents an exceptional type of preservation herein associated with a rapid variation in phreatic interdune water level and the subsequent establishment of anoxic and reducing *** occurrence of exceptionally preserved liverwort colonies coincides with the sedimentary record of,at least,three seismite levels in the *** gathered from the site suggests that the water table of the oasis was controlled by a combination of(i)a positive creation of accommodation space due to subsidence associated with movement on syn-sedimentary extensional faults,and(ii)the rise and fall of the oasis water table controlled by the oscillations of the groundwater system due to orbital changes which appear to drive the variability of the climate *** groundwater levels flooded the oasis soil crusts and lead to the exceptional recurrent preservation of liverwort colonies at the oasis ***,considering the hypothesis of floating or riparian liverworts in the oasis pond waters,the fall in the level of the oasis water table placed the floating liverworts in contact with the

关键词： Oasis Cretaceous liverworts Colonies Extensional tectonics Solar cyclicity