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International Journal of Ophthalmology(English edition) 2014年第1期7卷 86-91页

作者： Alex Yuan Baseer U.Ahmad David Xu Rishi P.Singh Peter K.Kaiser daniel f.martin Jonathan E.Sears Andrew P.Schachat Justis P.Ehlers Vitreoretinal Service Cole Eye InstituteCleveland Clinic The Retina Institute

AIMTo compare the efficacy of ranibizumab and bevacizumab for macular edema due to retinal vein occlusion (RVO).

关键词： macular edema retinal vein occlusion bevacizumab ranibizumab optical coherence tomography

Complement-dependent neuroinflammation in spinal cord injury:from pathology to therapeutic implications

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Neural Regeneration Research 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar El Baba Ali Tfaily firas Kobeissy Juanmarco Gutierrez Gonzalez daniel Refai Gerald R.Rodts Christian Mustroph David Gimbel Jonathan Grossberg daniel L.Barrow Matthew f.Gary Ali M.Alawieh Department of Neurosurgery Emory University School of MedicineAtlantaGAUSA Department of Neurology Yale UniversityNew HavenCTUSA Center for Neurotrauma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cord injury remains a major cause of disability in young adults,and beyond acute decompression and rehabilitation,there are no pharmacological treatments to limit the progression of injury and optimize recovery in this *** the thorough investigation of the complement system in triggering and propagating cerebral neuroinflammation,a similar role for complement in spinal neuroinflammation is a focus of ongoing *** this work,we survey the current literature investigating the role of complement in spinal cord injury including the sources of complement proteins,triggers of complement activation,and role of effector functions in the *** study relevant data demonstrating the different triggers of complement activation after spinal cord injury including direct binding to cellular debris,and or activation via antibody binding to damage-associated molecular *** effector functions of complement have been implicated in spinal cord injury,and we critically evaluate recent studies on the dual role of complement anaphylatoxins in spinal cord injury while emphasizing the lack of pathophysiological understanding of the role of opsonins in spinal cord *** this pathophysiological review,we systematically review the different translational approaches used in preclinical models of spinal cord injury and discuss the challenges for future translation into human *** review emphasizes the need for future studies to dissect the roles of different complement pathways in the pathology of spinal cord injury,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the role of complement in white matter degeneration and regeneration using translational strategies to supplement genetic models.

关键词： complement neuroinflammation neuroplasticity regeneration spinal cord injury targeted therapy

The Chinese Export Boom:An Examination of the Detailed Trade Data

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China & World Economy 2013年第1期21卷 64-90页

作者： Brett Berger Robert f.martin Division of International finance Board of Governors of the Federal Reserve System Global Monetary and Sovereign Markets Division of International FinanceBoard of Governors of the Federal Reserve System

from 2000 to 2007, Chinese exports grew at a phenomenal pace. Our paper uses finely detailed Chinese export data （8-digit Harmonized Commodity Description and Coding System codes） combined with US trade data to explore how this was achieved. Although general explanations such as China ~ exchange rate policy no doubt played a role, we find that sector-specific stories, effective Chinese industrial policy and fortuitous timing were more critical The detailed trade data reveal that ＂＇new ＂＇ technology goods, such as cell phones, LCD screens and laptops, played a key role. finally, we use the data to examine the relationship between Chinese exports and global manufacturing, in particular US manufacturing employment. We find that competition from China in both domestic and foreign markets likely contributed to a significant decline in USA manufacturing employment, but that relatively low US investment and slow GDP growth in the US following the 2001 recession played an equally important role.

关键词： China export manufacturing trade

A new strategy for corrosion protection of porous stainless steel using polypyrrole films

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Journal of Materials Science & Technology 2020年第2期37卷 85-95页

作者： C.Garcia-Cabezon C.Garcia-Hernandez M.L.Rodriguez-Mendez f.martin-Pedrosa Materials Engineering E.I.I.Universidad de Valladolid47011 ValladolidSpain UVASENS E.I.I.Universidad de Valladolid47011 ValladolidSpain

In this work,a method to improve the protection against corrosion of porous sintered stainless steel is *** is based on the electrodeposition of polypyrrole(PPy)layers doped with a large size counterion such as dodecylbenzenesulphonic acid(DBSA),a conducting polymer with high corrosion resistance and good *** efficacy of PPy coating depends on the adequate adhesion between the metal substrate and the coating *** protection against corrosion has been tested using 316 L stainless steel(SS)powder sintered at different conditions to evaluate the effect of the sintering atmosphere(nitrogen and vacuum)and cooling rates(furnace and water)on corrosion resistance,while wrought 316 L SS has been used as reference *** addition,two electrochemical deposition techniques have been tested to select the most *** circuit potential evolution,anodic polarization measurements and electrochemical impedance spectra have been used to evaluate corrosion protection in phosphate buffer saline *** has been evidenced that a more homogeneous and stable coating was obtained in the case of porous stainless *** corrosion potential shifted to nobler values and the anodic polarization branch became more *** porous samples have a good passivation performance with a lower stable passive current density and a higher breakdown *** transfer electronic resistance and the impedance module increase more than one order of ***,the porosity of sintered stainless steel is seen as an advantage for the improvement of the adherence of the PPy *** best corrosion protection is found for samples sintered in nitrogen and water-cooled.

关键词： Stainless steel Powder metallurgy Protection corrosion Electrodeposited films Polymer coatings

Archaea, the tree of life, and cellular evolution in eukaryotes

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Science China Earth Sciences 2019年第3期62卷 489-506页

作者： Jing XIAO Lu fAN Dingfeng WU Yanbing XU Dengxun LAI William f.martin Ruixin ZHU Chuanlun ZHANG Department of Bioinformatics Tongji University Shenzhen Key Laboratory of Marine Archaea Geo-Omics Department of Ocean Science and Engineering Southern University of Science and Technology SUSTech Academy for Advanced Interdisciplinary Studies Southern University of Science and Technology Institute of Molecular Evolution Heinrich-Heine-University Universit?tsstr.1 Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology

The early history of life harbours many unresolved evolutionary questions, none more important than the genomic origin and cellular evolution of eukaryotes. An issue central to eukaryote origin concerns the position of eukaryotes in the tree of life and the relationship of the host lineage that acquired the mitochondrion some two billion years ago to lineages of modern-day archaea. Recent analyses indicate that the host lineage branches within the Archaea, prompting the search for novel archaeal lineages that can improve our understanding of the cellular evolution of eukaryotes. Here we give a brief review of the studies on Archaea, the tree of life and the cellular evolution of eukaryotes, which is followed by an overview of recent progress fueled by new genomic technologies and recent status of archaeal research in China. future directions for the study of early evolution are considered.

关键词： Archaea Tree of life Cellular evolution of eukaryotes Metagenomics Bioinformatics

Movement analysis in the diagnosis and management of Parkinson’s disease

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Neural Regeneration Research 2025年第2期20卷 485-486页

作者： Johannes Burtscher Nicolas Bourdillon Jules MJanssen Daalen Aurélien Patoz Julien fBally martin Kopp Davide Malatesta Bastiaan RBloem Institute of Sport Sciences University of LausanneLausanneSwitzerland Radboud University Medical Center Department of NeurologyDonders Institute for BrainCognition and BehaviorCenter of Expertise for Parkinson and Movement DisordersNijmegenThe Netherlands Radboud University Medical Center Department of Medical BioSciencesNijmegenThe Netherlands Research and Development Department Volodalen Swiss Sport LabAigleSwitzerland Service of Neurology Department of Clinical NeurosciencesLausanne University Hospital(CHUV)and University of Lausanne(UNIL)LausanneSwitzerland Department of Sport Science University of InnsbruckInnsbruckAustria

Challenges in the diagnosis and treatment of Parkinson’s disease:Parkinson’s disease(PD)is an increasingly prevalent neurodegenerative disease,at first sight primarily characterized by motor symptoms,although non-motor symptoms also constitute a major part of the overall ***,this disease cannot be diagnosed reliably until a large part of the vulnerable dopaminergic neurons has been irretrievably lost,and the disease progresses *** biological criteria for PD have been proposed recently and might eventually improve early diagnosis,but they require further validation,and their use will initially be restricted to a research environment(Darweesh et al.,2024).

关键词： diagnosis Clinical eventually

OBSERVING THE HEAT EQUATION ON A TORUS ALONG A DENSE GEODESIC

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Systems Science and Mathematical Sciences 1991年第2期4卷 186-192页

作者： Lance D.Drager Robert L.foote Clyde f.martin Department of Mathematics Texas Tech.University.LubbockTX 79409USA Department of Mathematics Wabash CollegeCrawfordsvilleIN 47933USA Department of Mathematics Texas Tech.UniversityLubbockTX 79409USA

Several authors have considered observability problems for the heat equation and relatedpartial differential equations.A basic problem is to determine what kinds of sampling providesufficient information to uniquely determine the initial heat *** address the case wherethe temperature is measured while travelling along a *** consider the special case where the space is a flat torus(of arbitrary dimension)and thecurve is a *** is shown that,in this case,the observed temperature is sufficient informationto uniquely determine the initial heat distribution if and only if the geodesic is dense in the *** the case of a torus,fourier analysis techniques can be used to write down the solution of theheat *** allows us to derive an explicit representation of the observed temperature interms of the initial *** use this representation and some ideas from the theory ofalmost periodic functions to show that the fourier coefficients of the initial distribution can berecovered from the observation.

关键词： Observability heat equation inverse problems

Improvements in tribological and anticorrosion performance of porous Ti–6Al–4V via PEO coating

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friction 2021年第5期9卷 1303-1318页

作者： C.Garcia-Cabezón M.L.Rodríguez-Méndez V.AmigóBorrás R.Bayón C.Salvo-Comino C.Garcia-Hernandez f.martin-Pedrosa Materials Engineering E.I.I.Universidad de ValladolidValladolid 47011Spain BioecoUVA Research Institute Universidad de ValladolidValladolid 47011Spain Group UVASENS Escuela de Ingenierías IndustrialesUniversidad de ValladolidValladolid 47011Spain Instituto de Tecnología de Materials Univesitat Politécnica de ValenciaValencia 46022Spain Tribology Unit Fundación IK4-TeknikerEibar 20600Spain

Medical implants manufactured using biomaterial Ti–6Al–4V exhibit some *** higher elastic modulus than that of natural bone can cause stress shielding *** can be avoided using Ti–6Al–4V with pores in the implant ***,poor corrosion and tribocorrosion behaviors are yielded because of the large area exposed to the *** mitigate both issues,coating technologies can be *** plasma electrolytic oxidation(PEO)process is a cost‐effective process that has been used successfully in nonporous Ti *** this study,two PEO coatings with different amounts of Ca/P are ***,reports regarding their application in porous materials are *** effects of PEO treatments on corrosion and tribocorrosion in Ti–6Al–4V powder metallurgy are analyzed *** porous materials provide an efficient surface for PEO coatings,as demonstrated via scanning electron microscopy(SEM)and atomic force microscopy(AfM),and the porosity of the substrates improved the adherence of the *** corrosion resistance measured via electrochemical impedance spectroscopy confirmed the beneficial effect of the coatings,particularly for long exposure *** lower roughness,small pore size,and more compact film observed in the PEO–Ca/P sample resulted in favorable tribological and corrosion properties.

关键词： Ti‐based alloys corrosion tribocorrosion surface modification

Developing a web-based spatial decision support system for geothermal exploration at the Olkaria geothermal field

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International Journal of Digital Earth 2017年第11期10卷 1118-1145页

作者： daniel Mwaur martin Kad Institute of Geodesy and Geoinformation Science Technische Universität BerlinBerlinGermany

Geothermal exploration is a complex process that spans a number of *** a decision is made to drill a geothermal well,there is need for an extensive exploration process to determine the most suitable *** process of evaluating and analyzing data from individual scientific disciplines can be complex and *** have been made at solving this problem using GIS-based tools but the uptake of these tools is often hindered by the limited knowledge of GIS by decision *** paper presents an approach for solving the geothermal exploration question through a web-based spatial decision support system(SDSS)that incorporates the various geosciences through a multi-criteria spatial decision analysis *** results reveal a decision-making gap that is to be filled using a novel,automated exploration *** approach hypothesizes an easier and faster decision-making *** research focuses on Olkaria,an active geothermal area in Kenya,East Africa and highlights a pragmatic approach to identifying priority areas for *** evaluates contributions made by many disciplines in identifying potential sites ideal for harnessing geothermal energy and the gaps that emerge in an effort to synergize the results from the different disciplines.

关键词： GIS SDSS geothermal web based multi-criteria decision analysis

Blind Spots on Achilles’ Heel:The Limitations of Vulnerability and Resilience Mapping in Research

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International Journal of Disaster Risk Science 2014年第1期5卷 74-85页

作者： Jessica Heesen daniel f.Lorenz Michael Nagenborg Bettina Wenzel martin Voss International Center for Ethics in the Sciences and Humanities(IZEW) University of Tu¨bingen72074 TubingenGermany Disaster Research Unit(DRU) Freie Universita¨t Berlin12165 BerlinGermany Department of Philosophy University of Twente7500 AE EnschedeNetherlands

The mapping of vulnerability and resilience has become an important tool for vulnerability and resilience *** definition,maps are selective ***,the predominant methods of mapping also have *** addressing vulnerability and resilience,these limitations,barriers,and blind spots have to be taken into *** aspects cannot be easily mapped,such as specific forms of knowledge and interpretation,the processuality of vulnerability and resilience,the dynamics of social processes,the context of origin,the establishment of contingent interpretations,and so *** limitations are not only theoretically important,but also are practically significant,since maps themselves become *** are regarded as representations of reality,shape particular interpretations of vulnerability and resilience,and are used as a basis for *** the unmapped preconditions of mapping remain unconsidered,this can lead to problematic side effects.

关键词： Cartographic bias foucault Mapping constraints Vulnerability mapping