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Influence of Tomographic Slice Thickness and Field of View Variation on the Reproduction of Thin Bone Structures for Rapid Prototyping Purposes-An in Vitro Study

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Open Journal of Radiology 2013年第1期3卷 12-25页

作者： Maria Ines Meurer Kivia Pires Souza Aldo von Wangenheim daniel duarte abdala Luis Felipe de Souza Nobre Eduardo Meurer Jorge Vicente Lopes da Silva Department of Pathology Federal University of Santa CatarinaFlorianopolisBrazil Postgraduate Programme on Dento-Maxillo-Facial Radiology Health Sciences CenterFederal University of Santa CatarinaFlorianopolisBrazil Brazilian Institute for Digital Convergence Federal University of Santa CatarinaFlorianopolisBrazil Department of Computer Sciences Federal University of UberlandiaUberlandiaBrazil Department of Clinical Medicine Federal University of Santa CatarinaFlorianopolisBrazil Oral and Maxillofacial Surgery Homero de Miranda Gomes Regional HospitalSao JoseBrazil Renato Archer Center for Information Technology CampinasBrazil

This study assessed the influence of acquisition parameters of tomographic volumes on the reproduction of thin bone structures for rapid prototyping purposes. Two parameters were investigated: Field of View (FOV) and Slice Thickness (ST). The specimen was comprised of five pairs of 0.6 mm, 1.1 mm, 1.5 mm, 2.0 mm and 2.8 mm thick cortical bone plates. The plates were stuck into utility wax;the first plate of the pair was in vertical position while the second plate was oblique to the first one. Forty-five tomographic images were captured and separated into 3 groups of fifteen images. Each group had a specific FOV: 180 mm;250 mm and 430 mm, respectively. Within each of these three groups, tomographic slice thickness was varied for every five of the fifteen slices. Acquisitions were carried out with STs of 1 mm, 2.5 mm and 5 mm. The Cyclops Medical Station software was used in the voxel-to-voxel analysis of radiologic density, reaching a total of 1350 assessed images. ST and FOV variation influenced the reproduction of thin bone walls, and FOV was shown to be a very important parameter. The larger the acquisition FOV, the more reduction in the number of voxels within the range of reconstruction for cortical bone in all of the bone plates. The visual analysis of the images of very thin bone walls showed that there could be a sharp drop in the radiologic density value in several adjacent voxels, resulting in areas which might not be reproduced in the reconstruction.

关键词： Computed Tomography Rapid Prototyping Medical Rapid Prototyping Model

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Immune thrombocytopenic purpura induced by intestinal tuberculosis in a liver transplant recipient

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World Journal of Gastroenterology 2014年第25期20卷 8304-8308页

作者： Renata dos Santos Lugao Marina Pamponet Motta Matheus Freitas Cardoso de Azevedo Roque Gabriel Rezende de Lima Flávia de Azevedo Abrantes Edson abdala Flair José Carrilho daniel Ferraz de Campos Mazo Hepatology Branch Clinical DivisionDepartment of GastroenterologyUniversity of S?o Paulo School of Medicine S?o Paulo 05403-000Brazil Liver and Gastrointestinal Transplant Division Department of GastroenterologyUniversity of S?o Paulo School of MedicineS?o Paulo 05403-000 Brazil Department of Infectious and Parasitic Diseases University of S?o Paulo School of Medicine S?o Paulo 05403-000 Brazil

A variety of clinical manifestations are associated directly or indirectly with tuberculosis. Among them, haematological abnormalities can be found in both the pulmonary and extrapulmonary forms of the disease. We report a case of immune thrombocytopenic purpura(ITP) associated with intestinal tuberculosis in a liver transplant recipient. The initial management of thrombocytopenia, with steroids and intravenous immunoglobulin, was not successful, and the lack oftuberculosis symptoms hampered a proper diagnostic evaluation. After the diagnosis of intestinal tuberculosis and the initiation of specific treatment, a progressive increase in the platelet count was observed. The mechanism of ITP associated with tuberculosis has not yet been well elucidated, but this condition should be considered in cases of ITP that are unresponsive to steroids and intravenous immunoglobulin, especially in immunocompromised patients and those from endemic areas.

关键词： Immune thrombocytopenic purpura Tuberculosis Liver transplant Thrombocytopenia Intestinal tuberculosis

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