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Role of home monitoring with iCare ONE rebound tonometer in glaucoma patients management

International Journal of Ophthalmology(English edition) 2021年第3期14卷 405-408页

作者： Eldar Rosenfeld Gilad Rabina dana Barequet Michael Mimouni Naomi Fischer Shimon Kurtz Department of Ophthalmology Tel Aviv Sourasky Medical CenterAffiliated to the Sackler Faculty of MedicineTel Aviv UniversityTel Aviv 64239Israel Department of Ophthalmology Rambam Health Care CarmpusAffiliated to Ruth Rappaport Faculty of MedicineTechnion-lsrael Institute of TechnologyHaifa 3109601Israel

AIM: To evaluate intraocular pressure(IOP) measurements and fluctuations using the i Care ONE rebound tonometer(RT-ONE), during home monitoring, in diagnosed and suspected glaucoma ***: A retrospective case series of consecutive patients with known glaucoma or glaucoma suspects who were followed-up and treated between January 2016 and January 2017. The study included 80 eyes of 40 patients with a mean age of 59.1±14.6 y(range, 24-78). All patients have undergone 4-5 d of IOP home monitoring with RT-ONE at morning, noon, afternoon, and night ***: Baseline mean IOP, as measured in the clinic(8 a.m.-12 p.m.), was 17.4±5.1 mm Hg, compared to RT-ONE home monitoring mean IOP of 15.6±4.1 mm Hg(P=0.002). Mean IOP was significantly lower at noon, afternoon and night times compared to clinic measured IOP and morning measurements(P=0.005). IOP peak measured during home monitoring was significantly higher compared to the clinic measured IOP(21.3±5.6 mm Hg and 17.4±5.1 mm Hg, P<0.001). IOP peaks during home monitoring demonstrated a majority of 47 peaks during morning measurements, compared to 23 at noon, 19 at afternoon and only 12 at night(P<0.001). The home monitoring results led to treatment modification of 44 eyes(55%), treatment regime was insufficient for 40(50%) ***: Home monitoring IOP with RT-ONE can provide good assessment of mean IOP, IOP fluctuations and peaks throughout the hours of the day, which lead to an accurate treatment for glaucoma patients.

关键词： glaucoma intraocular pressure home monitoring iCare ONE peak

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RANKL deletion in periodontal ligament and bone lining cells blocks orthodontic tooth movement

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International Journal of Oral Science 2018年第1期10卷 27-35页

作者： Chia-Ying Yang Hyeran Helen Jeon Ahmed Alshabab Yu Jin Lee Chun-Hsi Chung dana T. Graves Department of Orthodontics School of Dental Medicine University of Pennsylvania Philadelphia PA USA Department of Pedodontics School of Dental Medicine University of Pennsylvania Philadelphia PA USA

The bone remodeling process in response to orthodontic forces requires the activity of osteoclasts to allow teeth to move in the direction of the force applied. Receptor activator of nuclear factor-κB ligand(RANKL) is essential for this process although its cellular source in response to orthodontic forces has not been determined. Orthodontic tooth movement is considered to be an aseptic inflammatory process that is stimulated by leukocytes including T and B lymphocytes which are presumed to stimulate bone resorption. We determined whether periodontal ligament and bone lining cells were an essential source of RANKL by tamoxifen induced deletion of RANKL in which Cre recombinase was driven by a 3.2 kb reporter element of the Col1α1 gene in experimental mice(Col1α***+.RANKLf/f) and compared results with littermate controls(Col1α***-.RANKLf/f). By examination of Col1α***+.ROSA26 reporter mice we showed tissue specificity of tamoxifen induced Cre recombinase predominantly in the periodontal ligament and bone lining cells. Surprisingly we found that most of the orthodontic tooth movement and formation of osteoclasts was blocked in the experimental mice, which also had a reduced periodontal ligament space. Thus, we demonstrate for the first time that RANKL produced by periodontal ligament and bone lining cells provide the major driving force for tooth movement and osteoclastogenesis in response to orthodontic forces.

关键词： DEPENDENT UP-REGULATION OSTEOCLAST DIFFERENTIATION ALKALINE-PHOSPHATASE MECHANICAL VIBRATION PDL FIBROBLASTS GENE-TRANSFER B-CELLS EXPRESSION TISSUE COMPRESSION

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ExaHDF5: Delivering Efficient Parallel I/O on Exascale Computing Systems

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Journal of Computer Science & Technology 2020年第1期35卷 145-160页

作者： Suren Byna M.Scot Breitenfeld Bin Dong Quincey Koziol Elena Pourmal dana Robinson Jerome Soumagne Houjun Tang Venkatram Vishwanath Richard Warren Lawrence Berkeley National Laboratory BerkeleyCA 94597U.S.A The HDF Group ChampaignIL 61820U.S.A Argonne National Laboratory LemontIL 60439U.S.A

Scientific applications at exascale generate and analyze massive amounts of data.A critical requirement of these applications is the capability to access and manage this data efficiently on exascale *** I/O,the key technology enables moving data between compute nodes and storage,faces monumental challenges from new applications,memory,and storage architectures considered in the designs of exascale *** the storage hierarchy is expanding to include node-local persistent memory,burst buffers,etc.,as well as disk-based storage,data movement among these layers must be *** I/O libraries of the future should be capable of handling file sizes of many terabytes and *** this paper,we describe new capabilities we have developed in Hierarchical Data Format version 5(HDF5),the most popular parallel I/O library for scientific ***5 is one of the most used libraries at the leadership computing facilities for performing parallel I/O on existing HPC *** state-of-the-art features we describe include:Virtual Object Layer(VOL),Data Elevator,asynchronous I/O,full-featured single-writer and multiple-reader(Full SWMR),and parallel *** this paper,we introduce these features,their implementations,and the performance and feature benefits to applications and other libraries.

关键词： parallel I/O Hierarchical Data Format version 5(HDF5) I/O performance virtual object layer HDF5 optimizations

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Comparison of success rate and intraocular pressure spikes between selective laser trabeculoplasty and micropulse laser trabeculoplasty in African American and Hispanic patients

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International Journal of Ophthalmology(English edition) 2023年第1期16卷 75-80页

作者： Alexander Z Robin Palwasha Syar dana Darwish Catherine Thomas NMPfahler Agni Kakouri Thomas Patrianakos Michael Giovingo Department of Ophthalmology John H.StrogerJr.Hospital of Cook CountyChicagoIL 60612USA Rosalind Franklin University of Medicine and Science North ChicagoIL 60064USA Department of Ophthalmology and Visual Science University of Illinois at ChicagoChicagoIL 60612USA Department of General Surgery University of Texas at HoustonHoustonTX 77030USA

AIM:To examine the efficacy and safety of micropulse laser trabeculoplasty(MLT)versus selective laser trabeculoplasty(SLT)in a large cohort of primarily African American and Hispanic ***:A single center retrospective comparative cohort review conducted at Cook County Health facilities that included patients with a diagnosis of open angle glaucoma or ocular hypertension who received an SLT or MLT procedure between January 2017 and May ***:Totally 131 eyes of 99 patients were *** 77 eyes received SLT and 54 received *** out of 77 eyes in the SLT group(9.1%)and 1 out of 54 eyes in the MLT group(1.9%)had an IOP spike(defined as>5 mm Hg)at either 1h or 1wk after procedure(P=0.05,Chisquared test with Haldane-Anscombe correction).The procedure failure rate at one year was 50%for SLT and 48%for MLT(P=0.31).CONCLUSION:MLT has a significantly lower incidence of pressure spikes and a similar treatment failure rate at 1-year post-procedure,demonstrating that it is a reasonable alternative compared to SLT.

关键词： selective laser trabeculoplasty micropulse laser trabeculoplasty glaucoma open angle glaucoma ocular hypertension

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Agricultural development and food security： The way out of crisis

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Journal of Agricultural Science and Technology 2009年第12期3卷 51-62页

作者： Lewis-Ambrose dana Business and Computer Studies Department H. Lavity Stoutt Community College Tortola VGI 1 I0 B VI

The purpose of this study is to elicit how investments in agricultural development and food security would safeguard the Virgin Islands （BVI） and the Caribbean, by extension, from future global crisis. History shows that agriculture played a significant role in the rise of civilization globally and was the main contributor to the Caribbean economy before the 1950＇s. Overall, it was determined that the BVI population, in general, is desirous of more investment opportunities within the agricultural sector, to assist with the alleviation of poverty at the national level, to advance economic development and trade across the region and to make sustainable development more attainable for the Caribbean, as a whole. To do this, agricultural development and food security must become the focal point of the BVI and other Caribbean economies. Accordingly, the paper recommends that investment within the agricultural sector be undertaken more aggressively across the region. The mixed research approach method was used to validate these claims.

关键词： agricultural development Caribbean food security global financial crisis investment mixed research approachmethod

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The Relevance of CARICOM＇s Existence to the Virgin Islands in the Context of Globalization

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Chinese Business Review 2011年第12期10卷 1148-1155页

作者： dana Lewis-Ambrose H. Lavity Stoutt Community College Paraquita Bay Tortola the Virgin Islands

The purpose of this study was to consider the relevance of CARICOM＇s existence to the Virgin Islands （BVI）. Its relevance becomes more significant to the BVI and the Caribbean, by extension, when the globalization phenomenon is applied; a phenomenon that has been in existence for centuries. Overall, the study concluded that even though the BVI remains only an associate member of CARICOM and not of CSME, it still has an interest in the progress of the regional grouping and its trade initiatives. Over the years, CARICOM has been struggling with its identity as a unified grouping. Nonetheless, it was found that in an effort to combat the trade liberalization process, the grouping must find that inner connection to advance its agenda on the global stage. Accordingly, it has been suggested that CARICOM begin to focus on its strengths and opportunities in order for economic development across the region to occur. It has also been recommended that more serious considerations be taken towards the development of a comprehensive regional market for the trading of goods and services, that is, the Caribbean Single Market and Economy （CSME）. To substantiate its findings, the paper used the qualitative research approach, combined with a situation （SWOT） analysis.

关键词： CARICOM qualitative research method SWOT analysis the Virgin Islands

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Ru/C催化剂上香豆素加氢制八氢香豆素（英文）

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催化学报 2015年第7期36卷 957-960页

作者： dana Bílková Petr Jansa Iva Paterová Libor erveny DepartmentofOrganicTechnology InstituteofChemicalTechnologyPragueTechnickd516628Praha6CzechRepublic AromaPrahaa.s. Zidovice6441183HrobceCzechRepublic

The production of octahydrocoumarin,which can serve as a replacement for toxic coumarin,was investigated using 5% Ru on active carbon(Ru/C) as the catalyst for the hydrogenation of coumarin. The hydrogenation was studied by optimizing the reaction conditions(pressure,solvent and coumarin concentration). The activity and selectivity of the Ru/C catalyst were compared for different solvents. The mechanism of coumarin hydrogenation was deduced. The formation of side products was explained. The optimal hydrogenation reaction conditions were: 130 °C,10 MPa,60 wt% coumarin in methanol,and 0.5 wt%(based on coumarin) of Ru/C catalyst. At the complete conversion of coumarin,the selectivity to the desired product was 90%.

关键词：钌/碳催化剂加氢反应条件香豆素 RU 活性炭副产物氢化转化率

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EARTHQUAKE PATTERN IN CENTRAL EUROPE

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地震工程学报 1992年第4期 94-102页

作者： dana Procházková Geoscience Plickova 565 14900 Praha 4 Czechoslovakia

GEOLOGICAL CHARACTERISTICS OF THE REGION UNDER INVESTIGATION From the geological point of view. the study area (Fig. 1) is mainly formed by the Hercynides and Alpides. Central European Hercynides lie mostly on the outer margin of the Alpine.- Carpathian foredeep. Their principal outcrops are the Bohemian Massif. Black Forest. Vosges. the Rhine slaty mountain range. They are hidden below the platform sediments, between Munich and Berlin, and partly between the Oder and Vistula lineaments. Central European Alpides comprise the region

关键词：地震活动图象 EARTHQUAKE PATTERN IN CENTRAL EUROPE

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America's Best Castle Hotels

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空中英语教室（高级版．彭蒙惠英语） 2021年第9期 12-13,40页

作者： Lauren dana 不详

Although the United States doesn’t have a king or queen,[it]is home to dozens of castle hotels-some of which date back 200-plus years-fit for *** best part?Each property offers its own distinct and regal-inspired ***... 详细信息

关键词： property hough Castle

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The Effects of Pain Neuroscience Education with Conventional Physical Therapy on Chronic Plantar Fasciitis: A Case Study

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Open Journal of Therapy and Rehabilitation 2021年第2期9卷 57-69页

作者： Yahya Alfaifi dana Webb The Physical Therapy Department The First Medical Center Riyadh Saudi Arabia School of Physical Therapy & Rehabilitation Sciences Morsani College of Medicine University of South Florida Tampa USA

Background and Purpose: Plantar Fasciitis (PF) is a condition that affects the foot and causes complaints such as pain and stiffness. The most common symptom of this condition is pain. There are many treatment options to deal with this condition, such as conservative therapy, medications, and surgical interventions in rare cases. This case study aims to investigate the potential impact of pain neuroscience education (PNE), combined with a conventional Physical Therapy (PT) program on a 37-year-old-patient with chronic plantar fasciitis. Case description: A 37-year-old male health care professional presented to an outpatient physical therapy clinic with a diagnosis of chronic PF for around two years. The participant had tried several treatment options with no improvement of his symptoms. After undergoing a physical therapy evaluation, he was given a plan of care for twelve sessions by a skilled physical therapist for a six-week period, with each session consisting of 30 minutes of conventional PT, followed by 5 to 15 minutes of PNE. Results: After completing the prescribed plan of care, the patient reported a reduction in subjective symptoms via the Visual Analog Scale (VAS). He also reported improvement with symptoms and functional independence via the Foot Function Index (FFI). The patient reported no change in the dana;">quality of sleep via Pittsburg Sleep Quality Index (PSQI). Lastly, he demonstrated no objective improvement in foot pressure with the Navicular Drop Test. Discussion: This case report indicates that PNE, combined with conventional PT for PF can have a positive impact on subjective pain and foot function. PNE should involve many topics about the physiology of pain and the n

关键词： Neuroscience Pain Physical Therapy Chronic Plantar Fasciitis Case Study

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