检索结果-南通市图书馆

Science China Chemistry 2024年

作者： He Jiang dan Ai Jibiao Jin zh.ng Xie Wai-Yeung Wong Department of Applied Biology and Chemical Technology and Research Institute for Smart Energy The Hong Kong Polytechnic University School of Chemistry and Chemical Engineering University of Jinan The Hong Kong Polytechnic University Shenzh.n Research Institute

Circularly polarized luminescence(CPL) is of importance to advance science and technology with significant potential applications in information storage, spintronics and optoelectronic devices. Integrating CPL and the emission mechanism of thermally activated delayed fluorescence(TADF) has attracted considerable attention, because of their 100% internal quantum efficiency in theory and easily modified molecular structures for tunable photo-electrical properties. However, the typical donor-acceptor(D-A) architecture of CP-TADF emitters generally induces a broad emission profile with inferior color purity due to their large structural relaxation under the processes of excitation and emission. Recently, CP-multi-resonance(MR)-TADF emitters that concurrently display CPL activity, narrowband emission and high efficiency are emerging as the most suitable candidates for the next-generation organic light-emitting diode(OLED) display. In this review, the progress of CP-MR-TADF materials is reviewed in terms of the molecular design strategy, the common relationship between the molecular structures and optoelectronic properties, and their OLEDs performance. Finally, the opportunities and challenges in this research topic are discussed.

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

密植夏玉米穗部脱水及力学特性研究

玉米科学 2024年第2期32卷 84-94页

作者：彭丹丹徐开未陈远学四川农业大学资源学院成都611130

以仲玉3号和正红6号玉米为试材,设置6.75×10^(4)、8.25×10^(4)株/hm^(2)两个种植密度,研究密植条件下夏玉米子粒、穗轴脱水及力学特性的变化规律,探明二者之间的关系。结果表明,随着种植密度的增加,穗部器官脱水减慢、含水率增加,力... 详细信息

以仲玉3号和正红6号玉米为试材,设置6.75×10^(4)、8.25×10^(4)株/hm^(2)两个种植密度,研究密植条件下夏玉米子粒、穗轴脱水及力学特性的变化规律,探明二者之间的关系。结果表明,随着种植密度的增加,穗部器官脱水减慢、含水率增加,力学强度呈下降趋势。品种间穗部脱水及力学强度存在显著差异,且远大于种植密度及二者交互作用的影响。与正红6号(zh.)相比,仲玉3号(ZY3)脱水较快,到达适宜机械粒收含水率时所需吐丝后积温较少,收获时ZY3子粒压碎强度与穿刺强度大,穗轴抗折断力小,茎秆倒伏率低,机收性能更好。相关性分析显示,子粒与穗轴力学强度与含水率均呈显著负相关;穗轴抗折断力与干重、单位长度干重及单位体积干重呈极显著正相关,与穗轴长、长粗比呈极显著负相关。密度与品种对子粒产量存在无显著差异,随着种植密度的提高,茎秆倒伏率显著增大,ZY3生理成熟后脱水速率显著降低,达到宜机收子粒含水率所需积温增多。

关键词：夏玉米密植穗部脱水特性力学强度

前置胎盘患者剖宫产术后发生下肢静脉血栓的危险因素分析

在线全文

学校读者我要写书评

暂无评论

中国妇幼保健 2024年第1期39卷 85-88页

作者：葛丹丹吴朝勇绍兴市柯桥区妇幼保健院产科浙江绍兴312030

目的分析前置胎盘患者剖宫产术后发生下肢血栓的危险因素。方法回顾性分析2019年1月—2022年8月绍兴市柯桥区妇幼保健院收治的424例行剖宫产的前置胎盘患者的临床资料,根据患者是否发生下肢静脉血栓分为A组(发生下肢静脉血栓,106例)和B... 详细信息

目的分析前置胎盘患者剖宫产术后发生下肢血栓的危险因素。方法回顾性分析2019年1月—2022年8月绍兴市柯桥区妇幼保健院收治的424例行剖宫产的前置胎盘患者的临床资料,根据患者是否发生下肢静脉血栓分为A组(发生下肢静脉血栓,106例)和B组(未发生下肢静脉血栓,318例)。比较两组患者的临床资料,应用单因素分析和多因素logistic回归分析影响患者发生下肢静脉血栓的危险因素,并分析两组的母婴结局。结果经单因素分析显示,两组患者高血压史、饮酒史、吸烟史、糖尿病史、体质量指数(BMI)、ASA分级、手术时间及文化程度比较,差异均无统计学意义(均P>0.05);两组患者血液黏度、年龄、卧床时间、术中失血量及D-二聚体比较,差异均有统计学意义(均P<0.05)。经多因素logistic回归分析,高术中失血量、高D-二聚体、高血液黏度、长卧床时间及高龄是影响前置胎盘患者剖宫产术后发生下肢静脉血栓的独立危险因素(P<0.05)。A组早产、新生儿窒息、羊水污染、产后出血、死胎及低体质量儿的发生率明显高于B组,差异均有统计学意义(均P<0.05)。结论高术中失血量、高D-二聚体、高血液黏度、长卧床时间及高龄是影响前置胎盘患者剖宫产术后发生下肢静脉血栓的独立危险因素,临床可通过术后下肢静脉血栓常规筛查并加强治疗和护理,积极排除发生前置胎盘的风险,改善母婴结局。

关键词：前置胎盘下肢静脉血栓凝血功能剖宫产术母婴结局危险因素

Nuclear Factor-κB Signaling Mediates Antimony-induced Astrocyte Activation

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2021年第1期34卷 29-39页

作者： zh.NG Tao zh.NG Yu dan JIAO Man zh.Ye XU Shen Ya zh. Piao Yu zh.O Xin Yuan WU Qi Yun Department of Occupational Medicine and Environmental Toxicology School of Public HealthNantong UniversityNantong 226019JiangsuChina Fudan University Taizh.u Institute of Health Sciences Taizhou 225300JiangsuChina

Objective Antimony(Sb)has recently been identified as a novel nerve poison,although the cellular and molecular mechanisms underlying its neurotoxicity remain *** study aimed to assess the effects of the nuclear factor kappa B(NF-κB)signaling pathway on antimony-induced astrocyte *** Protein expression levels were detected by Western ***,cytoplasmic and nuclear fractions separation were used to assess the distribution of *** expression of protein in brain tissue sections was detected by *** levels of mRNAs were detected by Quantitative real-time polymerase chain reaction(qRT-PCR)and reverse transcriptionpolymerase chain reaction(RT-PCR).Results Antimony exposure triggered astrocyte proliferation and increased the expression of two critical protein markers of reactive astrogliosis,inducible nitric oxide synthase(iNOS)and glial fibrillary acidic protein(GFAP),indicating that antimony induced astrocyte activation in vivo and in *** exposure consistently upregulated the expression of inflammatory ***,it induced the NF-κB signaling,indicated by increased p65 phosphorylation and translocation to the ***-κB inhibition effectively attenuated antimony-induced astrocyte ***,antimony phosphorylated TGF-β-activated kinase 1(TAK1),while TAK1 inhibition alleviated antimonyinduced p65 phosphorylation and subsequent astrocyte *** Antimony activated astrocytes by activating the NF-κB signaling pathway.

关键词： Antimony Astrocyte activation Neurotoxicity NF-κB TAK1

基于“互联网+”新形态教材开发路径探索--以园林技术专业教材建设为例

在线全文

学校读者我要写书评

暂无评论

杨凌职业技术学院学报 2024年第2期23卷 67-71页

作者：陈丹李松杨凌职业技术学院陕西杨凌712100 陕西垚森园林景观有限公司陕西杨凌712100

“互联网+”时代背景下,融合信息数字化教学资源及传统纸质教材所形成的新形态教材在教育领域终将成为趋势。以园林技术专业教材为例,介绍基于“互联网+”新形态教材开发编写路径,以与园林工程设计课程植物种植工程单元活页式教材编写... 详细信息

“互联网+”时代背景下,融合信息数字化教学资源及传统纸质教材所形成的新形态教材在教育领域终将成为趋势。以园林技术专业教材为例,介绍基于“互联网+”新形态教材开发编写路径,以与园林工程设计课程植物种植工程单元活页式教材编写设计为实践,校企双元,将优秀教材内容数字化,通过信息技术实现资源立体呈现,供同类教材建设参考与借鉴。

关键词：互联网+ 新形态教材开发路径探索

Biomaterials affect cell-cell interactions in vitro in tissue engineering

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第4期63卷 62-72页

作者： dan He Haiyan Li Shanghai Jiao Tong University Affiliated Sixth People’s Hospital School of Biomedical EngineeringShanghai Jiao Tong University1954 Huashan RoadShanghai 200030China Med-X Research Institute School of Biomedical EngineeringShanghai Jiao Tong University1954 Huashan RoadShanghai200030China

The facts that most tissues or organs consist of a variety of cells suggest that interactions between different types of cells play critical roles in tissue or organ *** tissue engineering,the effects of biomaterials on cell-cell interactions have recently attracted increasing attention for better elucidating the mechanisms through which biomaterials promote tissue *** studies have focused on these effects of biomaterials on cell-cell *** this review,comprehensive information was provided about the existing cell co-culture technologies and the main behavioral modes of cell-cell *** effects of biomaterials on the cell-cell interactions in various types of tissue regeneration have been summarized and *** the end,the existing problems and future perspectives that would help promote the research of biomaterials in tissue engineering have been *** article can help researchers to understand the progress and importance of studying the effects of biomaterials on cell-cell interactions in tissue engineering and to choose the optimal cell-cell co-culture models for designing experiments.

关键词： organs biomaterials culture

Sex-and age-specific associations between abdominal fat and non-alcoholic fatty liver disease:a prospective cohort study

在线全文

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2023年第11期15卷 33-42页

作者： Hongli Chen Yuexing Liu dan Liu Yebei Liang zh.un zh. Keqing Dong Huating Li Yuqian Bao Jiarui Wu Xuhong Hou Weiping Jia Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai Diabetes InstituteShanghai Key Laboratory of Diabetes MellitusShanghai Key Clinical Center for Metabolic DiseaseShanghai 200233China General Practitioner Teams in Community Health Service Center of Nicheng Pudong New Area DistrictShanghai 201306China CAS Key Laboratory of Systems Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China

Obesity is closely related to non-alcoholic fatty liver disease(NAFLD).Although sex differences in body fat distribution have been well demonstrated,little is known about the sex-specific associations between adipose tissue and the development of *** community-based cohort data,we evaluated the associations between magnetic resonance imaging quantified areas of abdominal adipose tissue,including visceral adipose tissue(VAT)and subcutaneous adipose tissue(SAT),and incident NAFLD in 2830 participants(1205 males and 1625 females)aged 55–70 *** a 4.6-year median follow-up,the cumulative incidence rates of NAFLD increased with areas of VAT and SAT both in males and in *** analyses showed that the abovementioned positive associations were stronger in males than in females,especially in participants under 60 years *** contrast,these sex differences disappeared in those over 60 years ***,the risk of developing NAFLD increased non-linearly with increasing fat area in a sex-specific ***,sex-specific potential mediators,such as insulin resistance,lipid metabolism,inflammation,and adipokines,may exist in the associations between adipose tissue and *** study showed that the associations between abdominal fat and the risk of NAFLD were stratified by sex and age,highlighting the potential need for sex-and age-specific management of NAFLD.

关键词： visceral adipose tissue subcutaneous adipose tissue sex difference NAFLD incidence prospective study

Progress of continuously rotating detonation engines

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2016年第1期29卷 15-29页

作者： zh.u Rui Wu dan Wang Jianping Center for Combustion and Propulsion College of Engineering Peking University Center for Applied Physics and Technology Peking University State Key Laboratory for Turbulence & Complex Systems Peking University

Continuously rotating detonation engine （CRDE） is a focus for concern in the field of aerospace propulsion. It has several advantages, including one-initiation, high thermal efficiency and simple structure. Due to these characteristics, it is expected to bring revolutionary advance- ments to aviation and aerospace propulsion systems and now has drawn much attention throughout the world. In this paper, an overview of the development of CRDE is given from several aspects： basic concepts, applications, experimental studies, numerical simulations, and so on. Representative results and outstanding contributions are summarized and the unresolved issues for further engi- neerin~ applications of CRDE are 13rovided.

关键词： Aerospace Continuously rotatingdetonation CRDE Detonation engine Propulsion system

三峡水库中小洪水调度对支流库湾浮游植物的影响及机制

在线全文

学校读者我要写书评

暂无评论

环境科学 2024年第9期45卷 5308-5317页

作者：黎睿汤显强刘新波陈文重王丹阳任玉峰长江水利委员会长江科学院流域水环境研究所武汉430010 长江水利委员会长江科学院流域水资源与生态环境科学湖北省重点实验室武汉430010 中国长江电力股份有限公司智慧长江与水电科学湖北省重点实验室宜昌443000 长江水利委员会水文局长江三峡水文水资源勘测局宜昌443000

中小洪水调度已成为三峡水库汛期的主要调度方式,为研究三峡水库支流库湾浮游植物对中小洪水调度的响应,以三峡水库典型富营养化支流香溪河为对象,调查监测了2020~2021年汛期干支流浮游植物、营养盐及水体理化参数的时空分布特征,分析... 详细信息

中小洪水调度已成为三峡水库汛期的主要调度方式,为研究三峡水库支流库湾浮游植物对中小洪水调度的响应,以三峡水库典型富营养化支流香溪河为对象,调查监测了2020~2021年汛期干支流浮游植物、营养盐及水体理化参数的时空分布特征,分析了支流库湾浮游植物对中小洪水调度的响应特征.结果表明,中小洪水调度期间,香溪河库湾水体叶绿素a(Chl-a)随着坝前水位升高而降低,而在汛末蓄水期,Chl-a浓度再次升高.中小洪水调度期间,香溪河浮游植物以绿藻门和硅藻门为主,其群落组成随中小洪水调度而改变,当水位变幅增大时,以硅藻为主,当水位变幅较小时,以蓝、绿藻为主.Chl-a浓度对库湾水体TN浓度变化更为敏感,当库湾水体流速>0.25 m·s^(−1),或者悬浮泥沙浓度>10 mg·L^(−1)时,水体Chl-a浓度受到抑制.2010年以后,香溪河库湾典型水华暴发时间转变为以汛期为主,非汛期水华仅有2次,需要进一步关注汛期库湾藻类对中小洪水调度的响应.

关键词：三峡水库中小洪水调度浮游植物悬浮泥沙水动力条件

RAD51AP1基因表达在三阴性乳腺癌脑转移中的生物信息分析

在线全文

学校读者我要写书评

暂无评论

诊断学理论与实践 2024年第2期23卷 146-154页

作者：欧丹蔡钢陈佳艺上海交通大学医学院附属瑞金医院放射治疗科上海200025

目的:采用生物信息分析筛选三阴性乳腺癌脑转移相关差异性表达基因(differentially expressed genes,DEG),并探索影响预后的潜在作用机制。方法:在基因表达数据库(Gene Expression Omnibus, GEO)检索获得GSE76250(三阴性乳腺癌组织与正... 详细信息

目的:采用生物信息分析筛选三阴性乳腺癌脑转移相关差异性表达基因(differentially expressed genes,DEG),并探索影响预后的潜在作用机制。方法:在基因表达数据库(Gene Expression Omnibus, GEO)检索获得GSE76250(三阴性乳腺癌组织与正常乳腺组织)和GSE125989(三阴性乳腺癌脑转移病灶组织与三阴性乳腺癌原发灶组织) 2个数据集,筛选DEG。采用GO(Gene Ontology)分析和KEGG(Kyoto Encyclopedia of Genes and Genomes)分析寻找潜在的三阴性乳腺癌脑转移相关基因。通过癌症基因组图谱(The Cancer Genome Atlas, TCGA)数据库中的临床组织样本,验证相关基因表达水平与乳腺癌预后间的关系,并使用KEGG的基因集进行基因富集分析,评估DEG可能参与的信号通路。结果:在GSE125989和GSE76250数据集中共筛选出52个DEG,蛋白质相互作用网络(protein-protein interaction, PPI)分析提示RAD51AP1为三阴性乳腺癌脑转移的重要相关基因。TCGA数据分析显示,相较于癌旁组织RAD51AP1在乳腺癌组织中高表达;不同分子分型中,基底样型中乳腺癌PAD51AP1高表达。以RAD51AP1在癌组织表达中位数[log2(TPM+1)=3.85],将乳腺癌患者分为高表达和低表达组,生存分析显示,高表达患者的中位生存期差于低表达者[3 873 d比3 945 d,P<0.05,HR=1.40(1.01~1.94)]。通过GO、KEGG、基因富集分析(gene set enrichment analysis, GSEA)发现,RAD51AP1在细胞周期、DNA复制、错配修复等信号通路中有富集明显。基于细胞周期和DNA损伤修复信号通路相关蛋白信息构建PPI,筛选与RAD51AP1直接相互作用的蛋白质,其中增殖细胞核抗原(proliferating cell nuclear antigen,PCNA)与RAD51AP1的相关性较强(R=0.715,P<0.001)。结论:RAD51AP1在三阴性乳腺癌及其脑转移组织中高表达,可能作为潜在的诊断三阴性乳腺癌及预后不良的生物标志物,且其异常表达介导乳腺癌脑转移进程可能与PCNA相关。

关键词：三阴性乳腺癌脑转移生物信息学分析 RAD51AP1