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International Journal of Organic Chemistry 2013年第3期3卷 65-72页

作者： dalia hussein soliman Pharmaceutical Chemistry Department Faculty of Pharmacy Al-Azhar University Cairo Egypt

A new series of quinoxaline 1,4-di-N-oxides were synthesized and evaluated for their antibacterial and antifungal activities. The best result was demonstrated by 3-amino-N-(4-methoxyphenyl)-2-quinoxalinecarboxamide 1,4-di-N-oxide 4e, MIC (0.24 μg/ml) against Aspergillus fumigatus, and (0.12 μg/ml) against Streptococcus pneumonia.

关键词： Quinoxaline 1 4-di-N-Oxide Beirut Reaction Benzofuroxanes β-Ketoamide β-Cyanoamide Antibacterial Antifungal

Antifouling evaluation of extracts from Red Sea soft corals against primary biofilm and biofouling

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 991-997页

作者： Yosry Abdel Aziz soliman Ahmed Mohammed Brahim Ahmed hussein Moustafa Mohamed Abdel Fattah Hamed Marine Chemistry Lab. Marine Environment DivisionNational Institute of Oceanography and FisheriesSuezEgypt Department of Chemistry Faculty of ScienceZagazig UniversityZagazigEgypt

Objectives: To evaluate antifouling property of extracts from Red Sea soft corals against primary biofilm and ***: Seven species of soft corals Sarcophyton glaucum(a), Sinularia compressa,Sinularia cruciata(a), Heteroxenia fuscescens(a), Sarcophyton glaucum(b), Heteroxenia fuscescens(b) and Sinularia cruciata(b) were chosen to test their extracts as antibacterial and antifouling agents in Eastern Harbour of Alexandria, Mediterranean *** compounds of soft corals were extracted by using methanol and concentrated under vacuum. The residues of extracts were mixed in formulation of inert paint which consisted of rosin, chlorinated rubber and ferrous oxide against micro and macro fouling organisms. The formulated paints were then applied on PVC panels twice by brush,hanged in a steel frame and immersed in Eastern Harbour of Alexandria Mediterranean Sea followed by visual inspection and photographic ***: After 185 days of immersion in seawater, the antifouling results agreed with the antibacterial results where extracts of Sinularia compressa and Heteroxenia fuscescens(b) gave the best activity against marine fouling tubeworms and barnacles. The inhibition activity was correlated with the major functional groups(hydroxyl, amino, carbonyl,aliphatic(fatty acids), C]C of alkene or aromatic rings and CeC l of aryl halides) of the ***: The strong antifouling activity makes them promising candidates for new antifouling additives. After the screening and application of natural organic compounds from soft corals, marine organisms show activity against micro and macro fouling organisms.

关键词： Antibacterial Antifouling Paints Seawater Marine Organisms

Comparative Study between Lidocaine 2% and Dexamethasone Local Wound Infiltration Effect on Postoperative Pain Post Mastectomy: A Randomized Controlled Study

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Advances in Breast Cancer Research 2018年第4期7卷 243-249页

作者： hussein O. soliman National Cancer Institute Cairo Egypt

Objective: To compare the efficacy and safety of Lidocaine 2% versus Dexamethasone injected locally in mastectomy wound as pain relieving agents. Materials & Methods: A randomized single-blinded study in which 50 patients candidate for Mastectomy were included. Participants were equally randomized into two groups;Group A, in which patients received 10 ml Lidocaine 2% and Group B, in which patients received 16 mL Dexamethasone. In both groups, the drugs were given via local infiltration in the subcutaneous layer of the Mastectomy wound immediately after skin closure. Pain control was assessed post-operatively in the first 24 hours using the visual analogue scale (VAS) in addition the need for additional analgesia was recorded. Results: There was a statistically significant lower VAS score in group A (Lidocaine group) when compared to those in group B (Dexamethasone group) 1 h, 6 h, 12 h postoperatively with no significance 24 h postoperatively (36% vs 64% 1 h, 28% vs 64% 6 h, 30% vs 72% 12 h and, 80% vs 60% 24 h). This statistical significance was evident throughout the post-operative hours (1 h, 6 h, 12 h). Though local Lidocaine caused marked improvement of pain in bigger number of patients in group A than group B, yet it showed no statistical significance 24 h post-mastectomy. Furthermore, the number of participants that needed additional doses of analgesia lower in group A (48% vs 56%) in comparison to group B, but still showed no statistical significance. Conclusion: Local injection of Lidocaine 2% in Mastectomy wounds, has an upper hand in reducing the post-operative pain and showed a lesser need for post-operative analgesia when compared to local Dexamethasone injection.

关键词： Post-Mastectomy Pain Lidocaine Dexamethasone

The Efficacy of Podophyllin Cautery Added to Surgical Excision for Eradication of Vulvar Condylomata Accuminata;Randomized Controlled Trial

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Journal of Cancer Therapy 2018年第7期9卷 559-567页

作者： hussein O. soliman Yossra Lashin Department of Surgical Oncology National Cancer Institute Cairo University Giza Egypt Department of Gynecology and Obstetrics Faculty of Medicine Cairo University Giza Egypt

Context: Condyloma acuminatum is a common morbidity caused by human papillomavirus infection. Objective: To compare the recurrence rate after surgical excision with or without podophyllin cautery. Design, Setting, Participants: Sixty women were enrolled in a study that was conducted in Cairo from Jan-2017 to Mar-2018. Interventions: All women received the same preparations. After randomization;in the study group (N = 30), podophyllin cautery was added to surgical removal in the follow-up period. In the control group (N = 30), only surgical removal was used. Main Outcome Measure: The main outcome measure was the estimation of the recurrence of the lesion during the follow-up period. The secondary outcome measures were the incidence of adverse events. Results: Both groups were comparable (p-value > 0.05) with regard to the age and BMI. Recurrence was significantly lower (P = 0.001) in the study group than the control group. In the study group, five cases (17.2%) have recurrence whereas, in the control group, 18 (60.0%) had suffered recurrence. The ARR was 42.8% (CI 95%: 18% - 60.9%) with RR of 0.29 (CI 95%: 0.12% - 0.67%) and NNT2 (CI 95%: 6% - 2%). During the follow-up period, 19 cases (65.5%) of the study group experienced pain versus only eight cases (26.7%) in the control group (p = 0.003). However, the development of scars was less in the study group 7 (24.1%) than in the control group 19 (63.3%), (p = 0.002). Conclusion: Podophyllin cautery, when added to surgical removal, is effective in decreasing the incidence recurrence in cases with condylomata acuminata.

关键词： Condyloma Acuminatum Recurrence Adverse Events Podophyllin Cautery Surgical Excision

Antioxidant Properties of Fermented Camel Milk Prepared Using Different Microbial Cultures

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Food and Nutrition Sciences 2022年第11期13卷 861-877页

作者： Nagwa hussein Ismail Abou-soliman Mahmoud Ibrahim El-Sayed Sameh Awad Department of Animal Breeding Animal and Poultry Production Division Desert Research Centre Cairo Egypt Department of Dairy Technology Research Food Technology Research Institute Agricultural Research Center Giza Egypt Department of Dairy Science and Technology Faculty of Agriculture Alexandria University Alexandria Egypt

This study investigated the effect of using different combinations of commercial starter culture and lactobacilli strains on the antioxidant properties of fermented camel milk for 14 days. The bacterial strains included Lb. casei subsp. casei B-1922, Lb. paracasei subsp. paracasei B-4560, Lb. rhamnosus B-442 and Lb. rhamnosus B-1445. The antioxidant activity of fermented milk was estimated using DPPH radical scavenging activity, ferrous ion chelating activity (FCA) and ferric reducing power assays. The total phenolic content (TPC), titratable acidity, proteolysis degree and sensory acceptability of samples were also evaluated. The results showed that all the studied parameters were affected by both the type of starter culture and storage. Samples containing the commercial starter and Lb. rhamnosus B-1445 had the highest DPPH radical scavenging activity and TPC throughout storage. Fermented milks prepared using the commercial starter and Lb. rhamnosus B-442 or Lb. paracasei retained their high FCA and reducing power throughout storage compared to the other samples. Fermented milk containing the commercial starter and Lb. casei showed the lowest antioxidant activity. The DPPH scavenging activity for all fermented milks decreased sharply during storage, while the change in FCA, reducing power and TPC differed among the samples during storage. The highest acidity was observed in the samples containing the commercial starter and Lb. paracasei, while fermented milk prepared using commercial starter and Lb. rhamnosus B-1445 had the lowest acidity. Samples containing the commercial starter and Lb. casei had the greatest proteolysis during the first week of storage, while samples containing the commercial starter and Lb. rhamnosus B-1445 had the highest proteolysis on day 14. Fermented milks with commercial starter and Lb. rhamnosus B-1445 or Lb. paracasei were the most acceptable products, while samples containing the commercial starter and Lb. casei were less acceptable.

关键词： Antioxidant Activity Fermented Camel Milk Lactobacilli

Improving the Antioxidant Properties of Fermented Camel Milk Using Some Strains of <i>Lactobacillus</i>

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Food and Nutrition Sciences 2021年第4期12卷 352-371页

作者： Mahmoud Ibrahim El-Sayed Sameh Awad Nagwa hussein Ismail Abou-soliman Department of Dairy Technology Research Food Technology Research Institute ARC Giza Egypt Dairy Microorganisms and Cheese Research Laboratory (DMCR) Department of Dairy Science and Technology Faculty of Agriculture Alexandria University Alexandria Egypt Animal Breeding Department Animal and Poultry Production Division Desert Research Centre Matariya Cairo Egypt

This study aimed at improving the antioxidant capacity of fermented camel milk using some single strains of Lactobacillus (Lb. helveticus B-734, Lb. casei subsp. casei B-1922, Lb. paracasei subsp. paracasei B-4560, Lb... 详细信息

关键词： Camel Milk Fermented Milk Antioxidant Activity Lactobacillus

Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults

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World Journal of Nephrology 2016年第6期5卷 517-523页

作者： Sahier Omar El-Khashab Eman El-Sayed Mohamed Mahmoud A soliman hussein Heshmat Kassem Amin Roshdy soliman Department of Nephrology Kasr Al-Ainy Cairo University Department of Medicine Kasr Al-Ainy Cairo University Department of Cardiology Kasr AlAiny Cairo University

AIM To compare the effects of renal transplantation on cardiac functions in children and *** One hundred and ten patients attending the nephrology outpatient clinic were enrolled in this study and were divided into six groups. The first two groups consisted each of 30 renal transplant patients who had a successful renal transplantation more than six months, but less than one year. Group Ⅰ were less than 18 years and group Ⅱ were more than 18 years. The third and fourth groups, each were 20 chronic renal failure patients on regular hemodialysis. Again, group Ⅲ were less than 18 years and group Ⅳ were more than 18 years. Group Ⅴ and Ⅵ(The control Groups) consisted each of 5 subjects below and above 18 years of age, respectively with normal kidney functions. All patients were subjected to history and examination. The kidney functions and the hemoglobin were analyzed. Afterobtaining informed consent, echocardiography was done to all *** There was a statistically significant improvement(P < 0.0001) in all cardiac parameters. A regression in left ventricular end diastolic volume(LVED) both in children(4.7 ± 0.8 to 4.2 ± 0.5) and in adults(5.9 ± 0.7 to 4.9 ± 0.6) were found. There was a regression in left ventricular end systolic volume(LVES) both in children(3.1 ± 0.6 to 2.4 ± 0.4) and in adults(4.1 ± 0.9 to 3.1 ± 0.5). Fractional shortening improves both in children(32.6 ± 5.3 to 41.7 ± 7.6) and in adults(29.0 ± 6.6 to 36.5 ± 4.1). The improvement in ejection fraction(EF) was higher in children(59.7 ± 7.0 to 71.9 ± 6.1) than in adults(52.0 ± 12.5 to 64.8 ± 5.9). However, this degree of improvement(in children: 12.2 ± 5.1) did not show statistical difference(P-value 0.8), when compared to adults(12.7 ± 9.8). CONCLUSION After renal transplantation cardiac functions and morphology(EF/LVED/LVES) do improve markedly and rapidly in both children and adults.

关键词： Echocardiography chronic renal disease Renal transplantation Cardiac problems

The Impact of Microbial Transglutaminase on the Quality and Antioxidant Activity of Camel-Milk Soft Cheese

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Food and Nutrition Sciences 2020年第3期11卷 153-171页

作者： Nagwa hussein Ismail Abou-soliman Sameh Awad Mahmoud Ibrahim El-Sayed Animal Breeding Department Animal and Poultry Production Division Desert Research Centre Matariya Cairo Egypt Department of Dairy Science and Technology Faculty of Agriculture Alexandria University Alexandria Egypt Department of Dairy Technology Research Food Technology Research Institute Agricultural Research Center Giza Egypt

This study aimed at investigating the impact of adding microbial transglutaminase (MTGase) after rennet addition on some properties of fresh soft cheese made from camel milk. MTGase was added to milk at concentration of 80, 100 and 120 U/L after 20 and 30 min of renneting. The chemical composition, yield, hardness, antioxidant activity and sensory properties of cheese were estimated. Enzymatic protein crosslinking was analyzed by SDS-PAGE. Results revealed that MTGase-treated cheeses were higher in moisture and lower in protein content compared to control. In addition, the concentration of MTGase and time of addition significantly (P 0.05) impacted these parameters. Among treated cheeses, samples with 80 U of MTGase and addition time of 20 min were the highest in total solids and protein content. Adding MTGase significantly (P 0.05) increased the cheese yield, however, increased MTGase concentration at any time of addition did not improve it. The electrophoretic patterns of MTGase-cheese proteins showed a reduction in the intensity of caseins bands and the appearance of new protein fractions with high molecular weights. However, the changes in the intensity of the whey proteins bands were not sufficiently clear as caseins. The cheese hardness was significantly (P 0.05) affected by adding MTGase. Cheese containing 80 U of MTGase had the highest hardness value compared to control and other treated samples. The antioxidant activity of cheese was negatively influenced by adding the enzyme. The use of MTGase enhanced the mouthfeel, texture and overall acceptability of cheese. However, the effect of MTGase concentration and addition time was not significant (P > 0.05) on the sensory attributes. In conclusion, adding MTGase to milk at concentration of 80 U after 20 min of renneting is recommended to improve the yield, textural and some sensory properties of fresh soft cheese made from camel milk.

关键词： Camel Milk Soft Cheese Transglutaminase Texture and Yield Antioxi-dant Activity

Chimp Optimization Algorithm Based Feature Selection with Machine Learning for Medical Data Classification

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Computer Systems Science & Engineering 2023年第12期47卷 2791-2814页

作者： Firas Abedi Hayder M.A.Ghanimi Abeer D.Algarni Naglaa F.soliman Walid El-Shafai Ali Hashim Abbas Zahraa H.Kareem hussein Muhi Hariz Ahmed Alkhayyat Department of Mathematics College of EducationAl-Zahraa University for WomenKarbalaIraq Biomedical Engineering Department College of EngineeringUniversity ofWarith Al-AnbiyaaKarbalaIraq Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Computer Science Department Security Engineering LabPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt College of Information Technology Imam Jaafar Al-Sadiq UniversityAl-Muthanna66002Iraq Department of Medical Instrumentation Techniques Engineering Al-Mustaqbal University CollegeHillah51001Iraq Computer Engineering Department Mazaya University CollegeDhi QarIraq College of Technical Engineering the Islamic UniversityNajafIraq

Datamining plays a crucial role in extractingmeaningful knowledge fromlarge-scale data repositories,such as data warehouses and *** rule mining,a fundamental process in data mining,involves discovering correlations,patterns,and causal structures within *** the healthcare domain,association rules offer valuable opportunities for building knowledge bases,enabling intelligent diagnoses,and extracting invaluable information *** paper presents a novel approach called the Machine Learning based Association Rule Mining and Classification for Healthcare Data Management System(MLARMC-HDMS).The MLARMC-HDMS technique integrates classification and association rule mining(ARM)***,the chimp optimization algorithm-based feature selection(COAFS)technique is employed within MLARMC-HDMS to select relevant *** by the foraging behavior of chimpanzees,the COA algorithm mimics their search strategy for ***,the classification process utilizes stochastic gradient descent with a multilayer perceptron(SGD-MLP)model,while the Apriori algorithm determines attribute *** propose a COA-based feature selection approach for medical data classification using machine learning *** approach involves selecting pertinent features from medical datasets through COA and training machine learning models using the reduced feature *** evaluate the performance of our approach on various medical datasets employing diverse machine learning *** results demonstrate that our proposed approach surpasses alternative feature selection methods,achieving higher accuracy and precision rates in medical data classification *** study showcases the effectiveness and efficiency of the COA-based feature selection approach in identifying relevant features,thereby enhancing the diagnosis and treatment of various *** provide further validation,we conduct detailed experiments on a benchmark

关键词： Association rule mining data classification healthcare data machine learning parameter tuning data mining feature selection MLARMC-HDMS COA stochastic gradient descent Apriori algorithm

Computational Intelligence Driven Secure Unmanned Aerial Vehicle Image Classification in Smart City Environment

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Computer Systems Science & Engineering 2023年第12期47卷 3127-3144页

作者： Firas Abedi Hayder M.A.Ghanimi Abeer D.Algarni Naglaa F.soliman Walid El-Shafai Ali Hashim Abbas Zahraa H.Kareem hussein Muhi Hariz Ahmed Alkhayyat Department of Mathematics College of EducationAl-Zahraa University forWomenKarbalaIraq Biomedical Engineering Department College of EngineeringUniversity ofWarith Al-AnbiyaaKarbalaIraq Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Security Engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt College of Information Technology Imam Jaafar Al-Sadiq UniversityAl-Muthanna66002Iraq Department of Medical Instrumentation Techniques Engineering Al-Mustaqbal University CollegeHillah51001Iraq Computer Engineering Department Mazaya University CollegeDhi QarIraq College of Technical Engineering The Islamic UniversityNajafIraq

Computational intelligence(CI)is a group of nature-simulated computationalmodels and processes for addressing difficult real-life *** CI is useful in the UAV domain as it produces efficient,precise,and rapid ***,unmanned aerial vehicles(UAV)developed a hot research topic in the smart city *** the benefits of UAVs,security remains a major challenging *** addition,deep learning(DL)enabled image classification is useful for several applications such as land cover classification,smart buildings,*** paper proposes novel meta-heuristics with a deep learning-driven secure UAV image classification(MDLS-UAVIC)model in a smart city *** purpose of the MDLS-UAVIC algorithm is to securely encrypt the images and classify them into distinct class *** proposedMDLS-UAVIC model follows a two-stage process:encryption and image *** encryption technique for image encryption effectively encrypts the UAV ***,the image classification process involves anXception-based deep convolutional neural network for the feature extraction ***,shuffled shepherd optimization(SSO)with a recurrent neural network(RNN)model is applied for UAV image classification,showing the novelty of the *** experimental validation of the MDLS-UAVIC approach is tested utilizing a benchmark dataset,and the outcomes are examined in various *** achieved a high accuracy of 98%.

关键词： Computational intelligence unmanned aerial vehicles deep learning metaheuristics smart city image encryption image classification