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An attack-resilient distributed extended Kalman consensus filtering algorithm with applications to multi-UAV tracking problems

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Frontiers of Information Technology & Electronic Engineering 2024年第8期25卷 1110-1122页

作者： Yuru hu Wangyan LI Lifeng WU Zhensheng YU College of Science University of Shanghai for Science and TechnologyShanghai 200093China

This study investigates how the events of deception attacks are distributed during the fusion of multi-sensor nonlinear ***,a deception attack with limited energy(dale)is introduced under the framework of distributed extended Kalman consensus filtering(DEKCF).Next,a hypothesis testing-based mechanism to detect the abnormal data generated by dale,in the presence of the error term caused by the linearization of the nonlinear system,is *** the dale is detected,a new rectification strategy can be triggered to recalibrate the abnormal data,restoring it to its normal ***,an attack-resilient DEKCF(AR-DEKCF)algorithm is proposed,and its fusion estimation errors are demonstrated to satisfy the mean square exponential boundedness performance,under appropriate ***,the effectiveness of the AR-DEKCF algorithm is confirmed through simulations involving multi-unmanned aerial vehicle(multi-UAV)tracking problems.

关键词： Extended Kalman consensus filtering Hypothesis testing Rectification strategy Multi-UAV tracking

生成式人工智能应用于商务英语教学内容设计的研究

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深圳信息职业技术学院学报 2024年第3期22卷 7-14页

作者：胡文锐广州松田职业学院商贸学院广东广州511370

以ChatGPT为代表的生成式人工智能为解决商务英语专业教学缺乏语言环境、反馈效率低和教学内容陈旧等困境提供了新的思路,亟需验证人工智能生成内容的易读性问题。易读性评估立足于商务英语专业课程开展,通过设计教学主题和提示语,输入C... 详细信息

以ChatGPT为代表的生成式人工智能为解决商务英语专业教学缺乏语言环境、反馈效率低和教学内容陈旧等困境提供了新的思路,亟需验证人工智能生成内容的易读性问题。易读性评估立足于商务英语专业课程开展,通过设计教学主题和提示语,输入ChatGPT生成教学语料后使用Python语言和Pycharm软件进行Flesch、dale-Chall和McAlpine EFLAW易读性分析,可评估ChatGPT应用于教学内容设计的可行性。研究表明,ChatGPT生成内容难度略高于目标读者水平,符合规范语言的要求。学生反馈实验平均分趋近常模,实际应用难度适中,生成式人工智能应用于商务英语教学内容设计具有较高的可行性,但仍需克服内容重复率高、模型训练和人工审阅投入高等问题。

关键词： ChatGPT 生成式人工智能商务英语教学内容易读性

Dual Functions of Microglia in Ischemic Stroke

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Neuroscience Bulletin 2019年第5期35卷 921-933页

作者： Chuan Qin Luo-Qi Zhou Xiao-Tong Ma Zi-Wei hu Sheng Yang Man Chen dale B. Bosco Long-jun Wu Dai-Shi Tian Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Department of Neurology Mayo Clinic Rochester MN 55905 USA

Ischemic stroke is a leading cause of morbidity and mortality worldwide. Resident microglia are the principal immune cells of the brain, and the first to respond to the pathophysiological changes induced by ischemic stroke. Traditionally, it has been thought that microglial activation is deleterious in ischemic stroke, and therapies to suppress it have been intensively explored. However,increasing evidence suggests that microglial activation is also critical for neurogenesis, angiogenesis, and synaptic remodeling, thereby promoting functional recovery after cerebral ischemia. Here, we comprehensively review the dual role of microglia during the different phases of ischemic stroke, and the possible mechanisms controlling the post-ischemic activity of microglia. In addition, we discuss the dynamic interactions between microglia and other cells, such as neurons, astrocytes, oligodendrocytes,and endothelial cells within the brain parenchyma and the neurovascular unit.

关键词： Microglia Inflammation Ischemic stroke Signaling pathways

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海洋初级生产力的一维物理生态耦合模型

浙江大学学报（工学版） 2018年第5期52卷 1002-1013页

作者：胡晨孙志林 dale A.Kiefer 李明佳浙江大学海洋学院浙江杭州310058 University of Southern California Biological Sciences Department Los AngelesCA 90089USA

为了更有效研究海洋初级生产力量值,构建物理-生态耦合模型,探讨影响海洋初级生产力的动力及生态因素.通过增加对流和扩散模块、分离营养盐循环体系、改变浮游植物生长速率公式及加入叶绿素计算模块,分别优化Gill-Turner(简称GT)混合层... 详细信息

为了更有效研究海洋初级生产力量值,构建物理-生态耦合模型,探讨影响海洋初级生产力的动力及生态因素.通过增加对流和扩散模块、分离营养盐循环体系、改变浮游植物生长速率公式及加入叶绿素计算模块,分别优化Gill-Turner(简称GT)混合层模型与Schmittner(简称S)生态系统模型,进而建立新型物理-生态耦合模型.基于Mathematica二次开发平台对模型进行编程实现,用以模拟大西洋百慕大站和太平洋夏威夷站的海洋初级生产力,优化后耦合模型的模拟结果精度明显提高.模拟结果显示,两大海域初级生产力均具有冬季高夏季低的分布特征,混合层深度与浮游植物浓度是影响初级生产力分布的重要因素.

关键词：初级生产力物理-生态耦合模型大洋站

Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal damage

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中国药理学与毒理学杂志 2013年第3期 492-493页

作者： YU Hong Sonya GALES ZHENG Wei-jun QIN Qiu-ping dale ThuRMAN hu Li-ping QIAO jun-wen REN jin CHEN Ya-fei Russell BIALECKI Lew KINTER Nigel BARRASS Centre for Drug Safety Evaluation and Research Shanghai Institute of Materia Medica AstraZeneca R&D Alderley Park MacclesfieldUK Global Safety Assessment AstraZeneca R&D BostonMAUSA

OBjECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney *** Study #1,11 monkeys(2-3 /sex /group) were given vehicle or imipenem(180 mg·kg-1,iv infusion once daily for 7 d) and urine was collected on days xxxxx for biomarker *** Study #2,24 monkeys(3 /sex /group) were given of vehicle or imipenem(45,90 or 180 mg·kg-1,iv infusion once daily for 7 d).The following endpoints were assessed in both studies: clinical observations,body weight,food consumption,haematology,coagulation,blood chemistry,urine analysis,imipenem concentration /toxicokinetics (TK) and gross and microscopic *** Study #1: Imipenem causes minor body weight loss,increased urea and creatinine,and decreased phosphate in *** total protein and bilirubin were observed in the *** effects were progressive and most pronounced at days 7 and *** and relative kidney weights were increased in both *** histopathological findings were present in kidneys of the dosed monkeys,consisting of minimal to moderate tubular necrosis /degeneration /*** biomarkers(α-1 and β-2 microglobulin,clusterin,Tamm-Horsfall protein and vascular endothelial growth factor) increased progressively and significantly from day 2 onward and preceded notable changes in urinalysis or plasma chemistry on day 7 or 8,*** #2: There were similar findings to Study #1 in the 180 mg·kg-1 imipenem treatment *** total bilirubin and decreased of phosphate in plasma and an increase of urinary urobilinogen /ketones were observed in a dose related *** to imipenem 〔Cmax and AUC(0-3 h) 〕increased in proportion from 45-90 mg·kg-1 but more than in proportion from 90-180 mg·*** The no observed adverse effect level(NOAEL) for the imipenem induced kidney injury was identified as 90 mg·*** increases of five urinary biomark

关键词： imipenem toxicity biomarkers renal damage

3Com的一体化网络及其新一代无线服务解决方案

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现代电信科技 2000年第2期30卷 49-52页

作者： Houman Modarres Howard hu dale Eliason 3Com公司运营系统部 IP电话主管3Com公司无线产品经理

A finite element analysis of the stress distribution to the mandible from impact forces with various orientations of third molars

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journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第1期19卷 38-48页

作者： Yun-feng LIU Russell WANG dale A.BAUR Xian-feng jIANG Key Laboratory of E&M (Zhejiang University of Technology) Ministry of Education & Zhejiang Province Department of Comprehensive Care School of Dental Medicine Case Western Reserve University Department of Oral and Maxillofacial Surgery School of Dental Medicine Case Western Reserve University

Objective： To investigate the stress distribution to the mandible, with and without impacted third molars（IM3 s） at various orientations, resulting from a 2000-Newton impact force either from the anterior midline or from the body of the mandible. Materials and methods： A 3 D mandibular virtual model from a healthy dentate patient was created and the mechanical properties of the mandible were categorized to 9 levels based on the Hounsfield unit measured from computed tomography（CT） images. Von Mises stress distributions to the mandibular angle and condylar areas from static impact forces（Load I-front blow and Load II left blow） were evaluated using finite element analysis（FEA）. Six groups with IM3 were included： full horizontal bony, full vertical bony, full 450 mesioangular bony, partial horizontal bony, partial vertical, and partial 450 mesioangular bony impaction, and a baseline group with no third molars. Results： Von Mises stresses in the condyle and angle areas were higher for partially than for fully impacted third molars under both loading conditions, with partial horizontal IM3 showing the highest fracture risk. Stresses were higher on the contralateral than on the ipsilateral side. Under Load II, the angle area had the highest stress for various orientations of IM3 s. The condylar region had the highest stress when IM3 s were absent. Conclusions： High-impact forces are more likely to cause condylar rather than angular fracture when IM3 s are missing. The risk of mandibular fracture is higher for partially than fully impacted third molars, with the angulation of impaction having little effect on facture risk.

关键词： Finite element analysis Third molar Mandible Biomechanical simulation

Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal damage

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Evaluation of imipenem toxicity in cynomolgus macaques inclu...

Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal damage

2013年（第三届）中国药物毒理学年会暨药物非临床安全性评价研究论坛

OBjECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney *** Study #1,11 monkeys(2 -3/sex/group) were given vehicle or imipenem(180 mg·kg,iv infusion once daily for 7 d) and urine was collected on days xxxxx for biomarker *** Study #2,24 monkeys(3/sex/group) were given of vehicle or imipenem(45,90 or 180 mg·kg,iv infusion once daily for 7 d).The following endpoints were assessed in both studies:clinical observations,body weight, food consumption,haematology,coagulation,blood chemistry,urine analysis,imipenem concentration/toxicokinetics (TK) and gross and microscopic *** Study #1:Imipenem causes minor body weight loss,increased urea and creatinine,and decreased phosphate in *** total protein and bilirubin were observed in the urine. These effects were progressive and most pronounced at days 7 and *** and relative kidney weights were increased in both *** histopathological findings were present in kidneys of the dosed monkeys,consisting of minimal to moderate tubular necrosis/degeneration/*** biomarkers(α-1 andβ-2 microglobulin,clusterin, Tamm-Horsfall protein and vascular endothelial growth factor) increased progressively and significantly from day 2 onward and preceded notable changes in urinalysis or plasma chemistry on day 7 or 8,*** #2:There were similar findings to Study #1 in the 180 mg·kg imipenem treatment *** total bilirubin and decreased of phosphate in plasma and an increase of urinary urobilinogen/ketones were observed in a dose related *** to imipenem [C and AUC(0-3h))) increased in proportion from 45 -90 mg-kg but more than in proportion from 90-180 mg·kg. CONCLUSION The no observed adverse effect level(NOAEL) for the imipenem induced kidney injury was identified as 90 mg·*** increases of five urinary biomarkers of kidney toxicit

关键词： imipenem toxicity biomarkers renal damage

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Evaluation of imipenem toxicity in cynomolgus macaques inclu...