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Deciphering the Hidden Secrets between the Early Skin Wrinkling & the Metabolic (X) Syndrome with the Possible Reversal of This Process at the Molecular Level

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Journal of Cosmetics, Dermatological Sciences and Applications 2024年第1期14卷 45-68页

作者： dalal alsaadoun Dermatology Department King Faisal University Hofuf Kingdom of Saudi Arabia

The aging process is a group of degenerative changes that physiologically occur in most of the people in the elderly. This affects one or more of the human body systems. The treatment of diseases related to the aging process has a huge impact on the economy of all nations. Aging of the skin comes on the top and despite that, the results of the already present lines of treatment are not always satisfactory. This acts as a stimulus for us to dig deeper to discover the root causes of the premature aging of the skin. This was simply caused by the accumulation of repeated minute damage to the internal structure skin. In other words, if the degree of minute damage is more than the capacity of the skin to repair, the repeated micro-damage is presented in the long run as a skin wrinkling. Moreover, the skin acts as a mirror that reflects the internal structures of the human body. Thus, the more degenerative changes in the human body systems, the more the skin could become wrinkled. Our strategy to prevent or at least slow down the aging process of the skin depends on 2 main steps;the 1st is to reduce the micro-damage as can as possible, and the 2nd is to enhance the capacity of tissue regeneration to be able to reverse the already present damaged skin. As the 2 processes are synchronized with each other, this strategy would be considered the ideal for prevention of skin wrinkling especially premature ones. This not only reverses premature skin wrinkling but also protects it from future wrinklings. This review sharply pointed out the role of the functional collagen of the dermal layer of the skin in the prevention of skin wrinklings. Therefore, it would be the target to study how collagen works in the complex machinery of the dermal layer of the skin. This concept deeply believes that the recovery of dermal collagen has a much better effect than simply ingesting collagen or receiving a topical collagen booster. .

关键词： Collagen Skin Wrinkling Glycation Hyper-Insulinemia Hidden Obesity Vis-ceral Fat Inflammatory Cytokines

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Implementation and Evaluation of Dynamically Weighted Low Complexity Fair Queuing(DWLC-FQ) Algorithm for Packet Scheduling in WiMAX Networks

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China Communications 2016年第5期13卷 128-140页

作者： Zuber Patel Upena dalal Department of Electronics Engineering S V National Institute of Technology

Services provided by internet need guaranteed network performance. Efficient packet queuing and scheduling schemes play key role in achieving this. Internet engineering task force(IETF) has proposed Differentiated Services(Diff Serv) architecture for IP network which is based on classifying packets in to different service classes and scheduling them. Scheduling schemes of today's wireless broadband networks work on service differentiation. In this paper, we present a novel packet queue scheduling algorithm called dynamically weighted low complexity fair queuing(DWLC-FQ) which is an improvement over weighted fair queuing(WFQ) and worstcase fair weighted fair queuing+(WF2Q+). The proposed algorithm incorporates dynamic weight adjustment mechanism to cope with dynamics of data traffic such as burst and overload. It also reduces complexity associated with virtual time update and hence makes it suitable for high speed networks. Simulation results of proposed packet scheduling scheme demonstrate improvement in delay and drop rate performance for constant bit rate and video applications with very little or negligible impact on fairness.

关键词： fair queuing packet scheduling QoS virtual time WF2Q+ WFQ

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Co-seismic surface displacement of the June 21, 2022 M_(W)6 Khōst,Afghanistan earthquake from InSAR observations

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Geodesy and Geodynamics 2024年第3期15卷 201-208页

作者： Prohelika dalal Batakrushna Senapati Bhaskar Kundu Department of Earth and Atmospheric Sciences National Institute of TechnologyRourkelaOdisha 769008India

A robust estimation of the earthquake location, seismic moment, and fault geometry is essential for objective seismic hazard assessment. Seismic events in a remote location, specifically in the absence of seismic and GNSS networks, can be investigated effectively using the In SAR-based technique. This study adopts the Differential Interferometric SAR(DIn SAR) technique to quantify the co-seismic surface displacement caused by the June 21, 2022, Khōst M_(W)6 earthquake that occurred along the western plate boundary between the Indian and Eurasian plate. The interferograms show that the maximum surface deformation occurred on the northwest and southwest of the fault line. From coherence, the Line of Sight(LOS) displacement, and the co-seismic surface displacement analysis, it has been observed that surface deformation was most pronounced in the southwest region of the fault line, and the surface has moved to the opposite direction along the fault line, which indicates a sinistral slightly oblique strike-slip movement. This In SAR-based observation appears consistent with the seismic waveforms derived from co-seismic surface displacements. Further, it has been argued that the slip deficit accumulated during the period of the last about 48 years along the frontal region of the northward extension of the Suleiman range and associated fault zone is qualitatively estimated at about 1.5 m, which is consistent with the seismic waveforms derived finite slip model.

关键词： Seismic hazard Khōst earthquake DInSAR Slip deficit LOS displacement Finite slip model

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Non-static plane symmetric perfect fluid solutions and Killing symmetries in f(R,T)gravity

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Communications in Theoretical Physics 2024年第2期76卷 145-150页

作者： Preeti dalal Karanjeet Singh Sachin Kumar Department of Mathematics and Statistics Central University of PunjabBathinda151401PunjabIndia Department of Mathematics Jaypee University of Information TechnologySolan173234Himachal PradeshIndia

In this paper,the non-static solutions for perfect fluid distribution with plane symmetry in f(R,T)gravitational theory are ***,using the Lie symmetries,symmetry reductions are performed for considered vector fields to reduce the number of independent ***,corresponding to each reduction,exact solutions are *** vectors lead to different conserved ***,we figure out the Killing vector fields corresponding to all derived *** derived solutions are further studied and it is observed that all of the obtained spacetimes,at least admit to the minimal symmetry group which consists of δ_(y),δ_(z) and -zδ_(y)+yδ_(z).The obtained metrics,admit to 3,4,6,and 10,Killing vector *** of linear momentum in the direction of y and z,and angular momentum along the x axis is provided by all derived solutions.

关键词： Einstein field equations perfect fluid solutions f(R T)gravity killing symmetries

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Mitigation of the impacts of electric vehicle charging on energy-star ratings for residential buildings in India

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Clean Energy 2023年第5期7卷 981-993页

作者： Rakesh dalal Devender Kumar Saini Electrical Cluster School of EngineeringUniversity of Petroleum and Energy Studies(UPES)DehradunIndia

The star-labelling programme for residential buildings was introduced by India in 2020 and applies to all residential buildings with no lower limit on the built-up area or electrical *** energy-star label for a residential building is awarded against the notified standard by the regulatory body and electric vehicles(EVs)have not been accommodated as a load for residential *** en-ergy consumption of an existing residential building is taken from a study already carried out and compared with the requirement of the Indian residential star-labelling programme with an EV as a plugged-in *** annual energy gap of 6060 kWh for the existing residential buildings considered in this study for five-star building energy labels increases to 7784 kWh if the EV load is added to the building *** residential building will lose two energy stars if it caters to the EV load and,to bridge this energy gap,the replace-ment of existing electrical appliances with five-star-rated energy appliances,employing grid-connected rooftop solar photovoltaics(PV)and retrofit of the building envelope are *** techno-economic potential of rooftop solar PV and building envelope retrofitting for existing residential buildings is explored using RETScreen®and eQUEST software,*** study establishes that the installation of rooftop solar PV can accommodate the additional load of EVs and can bridge half and three-quarters of the energy gap to achieve five energy stars for an existing building with and without EVs,*** is the most economical option among the options explored in this *** target Energy Performance Index is achievable by high-end energy consumers(12000 kWh/year)by additional measures,the replacement of inefficient electrical appliances and building envelope retrofitting in addition to the installation of rooftop solar PV.

关键词： energy conservation building code energy-star building envelope retrofit EV load

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Treatment modalities in Duane’s Retraction Syndrome

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International Journal of Ophthalmology(English edition) 2020年第2期13卷 278-283页

作者： Karim A Gaballah dalal Shawky Department of Ophthalmology Helwan UniversityCairo 11731Egypt Department of Ophthalmology Alexandria UniversityAlexandria 21568Egypt

●AIM:To study the different treatment modalities needed in cases of Duane’s Retraction Syndrome(DRS).●METHODS:This prospective study undergone in more than four years,in Alexandria,included 238 patients of DRS,including type I,162 patients(68%),type II 12 patients(5%)and type III 64 patients(27%).Surgery was indicated in 98(41%)of them,to eliminate abnormal head posture,deviation of the eye in primary position,severe retraction of the globe or cosmetically unacceptable upshoot with attempted adduction.●RESULTS:Type I was the most common and type II was the *** were predominant in this study,constituting 125 patients(52.5%),and males 113 patients(47.5%).Left eye was more affected,in 110 patients(46.2%),right eye in 91 patients(38.2%)and bilateral in 37 patients(15.6%).Amblyopia was found in 27 patients(11.3%)and treated in 13 patients under 10 years of age,by patching the normal ***-eight patients(41%)were operated,the results were most satisfactory and a nomogram is followed in the surgical plan.●CONCLUSION:The surgical management is needed in less than half of the cases and should be planned for every case individually according to the clinical findings,planned nomogram and modified intraoperatively according to the anatomical findings during surgery.

关键词： Duane’s Retraction Syndrome globe retraction globe upshoot medial rectus lateral rectus forced duction test

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Bounds on Fractional-Based Metric Dimension of Petersen Networks

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Computer Modeling in Engineering & Sciences 2023年第6期135卷 2697-2713页

作者： dalal Awadh Alrowaili Mohsin Raza Muhammad Javaid Mathematics Department College of ScienceJouf UniversityP.O.Box:2014SakakaSaudi Arabia Department of Mathematics School of ScienceUniversity of Management and TechnologyLahorePakistan

The problem of investigating the minimum set of landmarks consisting of auto-machines(Robots)in a connected network is studied with the concept of location number ormetric dimension of this *** this paper,we study the latest type of metric dimension called as local fractional metric dimension(LFMD)and find its upper bounds for generalized Petersen networks GP(n,3),where n≥*** n≥*** limiting values of LFMD for GP(n,3)are also obtained as 1(bounded)if n approaches to infinity.

关键词： Metric dimension local fractional metric dimension Petersen network local resolving neighborhoods

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Bridging the energy gap of India’s residential buildings by using rooftop solar PV systems for higher energy stars

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Clean Energy 2021年第3期5卷 423-432页

作者： Rakesh dalal Kamal Bansal Sapan Thapar Department of Energy University of Petroleum and Energy StudiesDehradunIndia Department of Energy and Environment TERI UniversityIndia

The residential-building sector in India consumes>25%of the total electricity and is the third-largest consumer of electricity;consumption increased by 26%between 2014 and *** has introduced a star-labelling programme for residential buildings that is applicable for all single-and multiple-dwelling units in the country for residential *** Energy Performance Index(EPI)of a building(annual energy consumption in kilowatt-hours per square metre of the building)is taken as an indicator for awarding the star label for residential *** gauging the EPI status of existing buildings,the electricity consumption of residential buildings(in kWh/m2/year)is established through a case study of the residential *** years of electricity bills are collected for an Indian residential society located in Palam,Delhi,analysed and benchmarked with the Indian residential star-labelling programme.A wide EPI gap is observed for existing buildings for five-star energy *** on existing electricity tariffs,the energy consumption of residential consumers and the Bureau of Energy Efficiency(BEE)’s proposed building ENERGY STAR labelling,a grid-integrated rooftop solar photovoltaic(PV)system is considered for achieving a higher star *** research study establishes the potential of grid-connected rooftop solar PV systems for residential buildings in Indian cities through a case study of ***-economic analysis of a grid-integrated 3-kWp rooftop solar PV plant is analysed by using RETScreen *** study establishes that an additional two stars can be achieved by existing buildings by using a grid-integrated rooftop solar PV *** for retrofit of a 3-kWp rooftop solar PV plant for Indian cites varies from 3 to 7 years.

关键词： ECBC residential star building rooftop solar PV RETScreen

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Stability analysis of drugdynamics model: A mat hematical approach

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International Journal of Biomathematics 2019年第4期12卷 153-184页

作者： Koyel Chakravarty D.C.dalal Department of Mathematics Indian Institute of Technology Guwahati Guwahati 781039 India Faculty of Science and Technology ICFAI University TripuraTripura 799210India

In this paper, a mathematical model of drug release from polymeric matrix and consequent intracellular drug transport is proposed and analyzed. Modeling of drug release is done through solubilization dynamics of drug particles, diffusion of the solubilized drug through the polymeric matrix in addition to reversible dissociation/recrystallization process. The interaction between drug-receptor, drug-plasma proteins along with other intracellular endosomal events is modeled. This leads to a mixed system of partial and ordinary differential equations with associated pertinent set of initial and boundary conditions. Furthermore, besides the stability of the proposed model, several sub-models are also studied for their stability criteria. Prominence is provided to the reduced model system having requisite relevance to the original system where quasi steady state approximation (QSSA) theory is utilized. For the model to be potent enough to generate appropriate predictive results for drug delivery, the stability properties of equilibrium in the mathematical model are analyzed both analytically and numerically. Numerical simulation in the embodiment of graphical representations speaks about various vital characteristics of the underlying physical phenomena along with the importance and sensitized impact of the model parameters controlling significant biological functions. Probed new therapies and clinical procedures could be assessed considering the present mathematical model and its analysis as the basis framework in order to effectively enhance therapeutic efficacy and improved patient compliance. The present study confirms the necessity of stability analysis study so that advocated mathematical model can effectively complement the real physiological behavior of pharmacokinetics.

关键词： Mathematical model drug polymeric matrix endosomal events quasi steady state approximation (QSSA) stability

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Green synthesis of bentonite-supported iron nanoparticles as a heterogeneous Fenton-like catalyst:Kinetics of decolorization of reactive blue 238 dye

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Water Science and Engineering 2020年第4期13卷 286-298页

作者： Ahmed Khudhair Hassan Ghayda Yaseen Al-Kindi dalal Ghanim Environment and Water Directorate Ministry of Science and TechnologyBaghdad 10070Iraq Sanitary and Environmental Branch Civil Engineering DepartmentUniversity of TechnologyBaghdad 10009Iraq

This study aimed to synthesize green tea nano zero-valent iron(GT-NZVI)and bentonite-supported green tea nano zero-valent iron(BGT-NZVI)nanoparticles using green tea extracts in an environmentally sustainable *** was used as a support material because it disperses and stabilizes GT-NZVI,and it helps to reduce the cost,increase the adsorption capacity of GT-NZVI,and decrease the optimum amount of GT-NZVI used in Fenton-like oxidation.A scanning electron microscope,an atomic force microscope,and a Fourier transform infrared spectroscope were used to characterize GT-NZVI and B-GT-NZVI,while the zeta potential was measured to evaluate the stability of iron *** decolorization kinetics of reactive blue 238(RB 238)dye in the aqueous phase in the Fenton-like oxidation process were investigated as *** effects of various experimental conditions such as reaction time,dosages of catalysts,concentration of H2O2,temperature,addition of inorganic salts,and other parameters were *** results show that the oxidative degradation efficiencies of RB 238 dye catalyzed by GT-NZVI and B-GT-NZVI were 93.5%and 96.2%,respectively,at the optimum reaction conditions as follows:c(H2O2)¼5 mmol/L,r(GT-NZVI)¼0.5 g/L or r(B-GT-NZVI)¼0.5 g/L,c(RB 238 dye)¼0.05 mmol/L,and pH¼2.5 at 180 *** best catalytic performance was exhibited when B-GT-NZVI was *** kinetic models were employed,and the second-order model was found to be the best model representing the experimental kinetic data of RB 238 *** value of activation energy decreased from 38.22 kJ/mol for GT-NZVI to 14.13 kJ/mol for *** indicates that the effect of B-GT-NZVI in decreasing the energy barrier is more pronounced than that of the GT-NZVI catalyst,leading to improved Fenton-like oxidation processes.©2020 Hohai *** and hosting by Elsevier *** is an open access article under the CC BY-NC-ND license(http://***/licenses/by-nc-nd/4.0/).

关键词： Green synthesis Bentonite-supported iron nanoparticles Azo dye Fenton-like process Kinetics

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