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Deep learning sheds new light on non-orthogonal optical multiplexing

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Light(Science & Applications) 2024年第5期13卷 808-809页

作者： Zhengzhong Huang Liangcai cao Department of Precision Instruments Tsinghua UniversityBeijingChina

A deep neural network for non-orthogonal input channel encoding is proposed to recover speckle images through a multimode *** novel approach could shed new light on the non-orthogonal optical multiplexing over a scatt... 详细信息

关键词： optical multiplexing scattering

Brain Mechanisms Underlying Panic Attack and Panic Disorder

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Neuroscience Bulletin 2024年第6期40卷 795-814页

作者： Xuyan Guan Peng cao Tsinghua Institute of Multidisciplinary Biomedical Research Tsinghua UniversityBeijing102206China National Institute of Biological Sciences(NIBS) Beijing102206China

Panic disorder is a psychiatric disorder characterized by recurrent panic attacks,with a prevalence of~4%in the general population,causing heavy personal and socioeconomic *** similarities of animal defense responses to clinical panic attack symptoms in humans make it possible to translate neuroanatomical pathways identified in animal studies to panic disorder in ***,in this review we first present a basic overview of panic disorder in humans including the main subtypes,models commonly used to trigger panic attacks,related hypotheses,the neurotransmitter systems that may be involved,and the current clinical treatments to give the reader a comprehensive understanding of panic *** animal section introduces the models that trigger panic-like behavior in animals and the brain regions that may be involved,providing insights for future elucidation of the neural circuit mechanisms behind panic attacks.

关键词： Panic disorder Panic attack Defense responses Animal studies Humans

Dysfunction of synaptic endocytic trafficking in Parkinson's disease

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Neural Regeneration Research 2024年第12期19卷 2649-2660页

作者： Xin Yi Ng Mian cao Programme in Neuroscience and Behavioural Disorders Duke-NUS Medical SchoolSingaporeSingapore Department of Physiology National University of SingaporeSingaporeSingapore

Parkinson's disease is characterized by the selective degeneration of dopamine neurons in the nigrostriatal pathway and dopamine deficiency in the *** precise reasons behind the specific degeneration of these dopamine neurons remain largely *** investigations have identified over 20 causative PARK genes and 90 genomic risk loci associated with both familial and sporadic Parkinson's ***,several of these genes are linked to the synaptic vesicle recycling process,particularly the clathrinmediated endocytosis *** suggests that impaired synaptic vesicle recycling might represent an early feature of Parkinson's disease,followed by axonal degeneration and the eventual loss of dopamine cell bodies in the midbrain via a"dying back"***,several new animal and cellular models with Parkinson's disease-linked mutations affecting the endocytic pathway have been created and extensively *** models faithfully recapitulate certain Parkinson's disease-like features at the animal,circuit,and cellular levels,and exhibit defects in synaptic membrane trafficking,further supporting the findings from human genetics and clinical *** this review,we will first summarize the cellular and molecular findings from the models of two Parkinson's disease-linked clathrin uncoating proteins:auxilin(DNAJC6/PARK19)and synaptojanin 1(SYNJ1/PARK20).The mouse models carrying these two PARK gene mutations phenocopy each other with specific dopamine terminal pathology and display a potent synergistic ***,we will delve into the involvement of several clathrin-mediated endocytosis-related proteins(GAK,endophilin A1,SAC2/INPP5 F,synaptotagmin-11),identified as Parkinson's disease risk factors through genome-wide association studies,in Parkinson's disease *** will also explore the direct or indirect roles of some common Parkinson's disease-linked proteins(alpha-synuclein(PARK1/4),Parkin(PARK2),and LRRK2(PARK

关键词： autophagy auxilin/PARK19 clathrin-mediated endocytosis dopamine neurons neurodegeneration nigrostriatal pathway Parkinson's disease synaptic vesicle recycling synaptojanin1/PARK20

Sub-10-nm-sized Au@AuxIr1-x metal-core/alloy-shell nanoparticles as highly durable catalysts for acidic water splitting

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National Science Review 2024年第4期11卷 130-140页

作者： Huimin Wang Zhe-ning Chen Yuanyuan Wang Dongshuang Wu Minna cao Fanfei Sun Rong cao State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences University of Chinese Academy of Sciences School of Materials Science and Engineering Nanyang Technological University Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied Physics Chinese Academy of Sciences Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China

The absence of efficient and durable catalysts for oxygen evolution reaction（OER） is the main obstacle to hydrogen production through water splitting in an acidic ele ***,we report a controllable synthesis method of surface IrOxwith changing Au/Ir compositions by constructing a range of sub-10-nm-sized core-shell nanocatalysts composed of an Au core and AuxIr1-xalloy *** particular,Au@Au0.43Ir0.57exhibits 4.5 times higher intrinsic OER activity than that of the commercial Ir/*** X-ray-based spectroscopies,electron microscopy and density functional theory calculations revealed a balanced binding of reaction intermediates with enhanced *** water-splitting cell using a load of 0.02 mgIr/cm2of Au@Au0.43Ir0.57as both anode and cathode can reach 10 mA/cm2at 1.52 V and maintain activity for at least194 h,which is better than the cell using the commercial couple Ir/C‖Pt/C（1.63 V,0.2 h）.

关键词： controllable synthesis of surface IrOx oxygen evolution reaction acidic water splitting catalytic stability transition metal catalysts

Angiogenesis in diseases:A half-century excursion from the initial therapeutic concept to current clinical benefits

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Chinese Medical Journal 2024年第6期137卷 636-637页

作者： Yihai cao Department of Microbiology Tumor and Cell BiologyKarolinska InstituteStockholm 17177Sweden

Except a few tissues such as the cornea and cartilage that are avascular,blood vessels constitute a significant proportion of tissue masses in virtually all *** physiological conditions,the adult vasculature remains quiescent to retain tissue and organ homeostatic *** few or too many blood vessels are associated with the onset and progression of many *** response to injuries,most tissues undergo repair by switching on angiogenesis,a key process of new blood vessel formation.^([1])Similarly,angiogenesis is often active in pathological tissues,including tumors and ischemic tissues to aggravate disease progression.

关键词： injuries organs diseases

Isolation performances and optimization of triple quasi-zero stiffness isolators

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Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 124-141页

作者： Yuntian Zhang Guangnan Zhu Qingjie cao School of Astronautics Harbin Institute of TechnologyHarbin 150001China

In this paper,triple quasi-zero stiffness(QZS)passive vibration isolators whose restoring force curve has a three-stage softening effect are ***-coupled SD oscillators with three independent geometrical parameters are used as negative stiffness mechanisms to achieve QZS characteristics at the origin and symmetrical positions on both sides of the *** performances of different triple QZS isolators are analyzed to show influences of the selection of QZS regions away from the origin on the range of isolation *** optimizations of system parameters are carried out to get a larger range of small restoring force regions and small stiffness *** performances of two triple QZS isolators are discussed to show the influence of different Pareto optimization solutions through the comparisons with single and double QZS *** showed that triple QZS isolators have both the advantages of single and double QZS isolators which results in better isolation performances under both small and large excitation *** improvement in isolation performances for triple QZS isolators is found with the decrease in average stiffness due to the appearance of two symmetrical QZS regions away from the *** displacements of QZS regions away from the origin result in better isolation performances when excitation amplitude is large,and triple QZS characteristics are similar to double QZS isolators at this *** restoring forces of QZS regions away from the origin lead to better isolation performances when excitation amplitude is small,and triple QZS characteristics are similar to single QZS isolators at this *** with the decrease in average stiffness,the improvement of isolation performances shows a hysteresis phenomenon due to the difference between static and dynamic characteristics.

关键词： triple quasi-zero stiffness vibration isolation Pareto optimization force transmissibility geometrical nonlinear

Lyapunov Conditions for Finite-Time Input-to-State Stability of Impulsive Switched Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 1057-1059页

作者： Taixiang Zhang Jinde cao Xiaodi Li the School of Mathematics Southeast UniversityNanjing 210096China the School of Mathematics and Statistics Shandong Normal UniversityJinan 250014Chi

Dear Editor,This letter studies finite-time input-to-state stability(FTISS)for impulsive switched systems.A set of Lyapunov-based conditions are established for guaranteeing FTISS *** constituent modes governing continuous dynamics are FTISS and discrete dynamics involving impulses are destabilizing,the FTISS can be retained if impulsive-switching signals satisfy an average dwell-time(ADT)condition.

关键词： property impulsive satisfy

Microstructural evolution and strengthening mechanism of aligned steel fiber cement-based tail backfills exposed to electromagnetic induction

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International Journal of Minerals,Metallurgy and Materials 2024年第11期31卷 2390-2403页

作者： Xihao Li Shuai cao Erol Yilmaz School of Civil and Resources Engineering University of Science and Technology BeijingBeijing 100083China State Key Laboratory of High-Efficient Mining and Safety of Metal Mines of Ministry of Education University of Science and Technology BeijingBeijing 100083China Department of Civil Engineering Geotechnical DivisionRecep Tayyip Erdogan UniversityFener Rize TR53100Turkey

Cemented tailings backfill(CTB)not only boosts mining safety and cuts surface environmental pollution but also recovers ores previously retained as pillars,thereby improving resource *** use of alternative reinforcing products,such as steel fiber(SF),has continuously strengthened CTB into *** approach prevents strength decreases over time and reinforces its long-term durability,especially when mining ore in adjacent underground *** this study,various microstructure and strength tests were performed on SFCTB,considering steel fiber ratio and electromagnetic induction strength *** findings show that combining steel fibers and their distribution dominantly influences the improvement of the fill’s ***’s strength rises by fiber insertion and has an evident correlation with fiber insertion and magnetic induction *** magnetic induction strength is 3×10^(-4) T,peak uniaxial compressive stress reaches 5.73 MPa for a fiber ratio of 2.0vol%.The cracks’expansion mainly started from the specimen’s upper part,which steadily expanded downward by increasing the load until damage *** doping of steel fiber and its directional distribution delayed crack *** the doping of steel fiber was 2.0vol%,SFCTBs showed excellent ductility *** energy required for fills to reach destruction increases when steel-fiber insertion and magnetic induction strength *** study provides notional references for steel fibers as underground filling additives to enhance the fill’s durability in the course of mining operations.

关键词： electromagnetic induction steel fiber cemented tailings backfill strength microstructure

Key-Part Attention Retrieval for Robotic Object Recognition

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Tsinghua Science and Technology 2024年第3期29卷 644-655页

作者： Jierui Liu Zhiqiang cao Yingbo Tang State KeyLaboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of SciencesBeijing100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China

The ability to recognize novel objects with a few visual samples is critical in the robotic *** methods mainly concern the recognition of inter-category objects,however,the object recognition fromdifferent sub-classes within the same category remains challenging due to their similar *** thispaper,we propose a key-part attention retrieval solution to distinguish novel objects of different sub-classesaccording to a few samples without ***,an object encoder,including convolutional neuralnetwork with attention and key-part aggregation,is designed to generate object attention map and extract theobject-level embedding,where object attention map from the middle stage of the backbone is used to guide thekey-part ***,to overcome the non-differentiability drawback of key-part attention,the objectencoder is trained in a two-step scheme,and a more stable object-level embedding is *** this basis,the potential objects are located from a scene image by mining connected domains of the attention *** the embedding of each potential object and embeddings from support data,the recognition of thepotential objects is *** effectiveness of the proposed method is verified by experiments.

关键词： key-part attention retrieval robotic object recognition