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Journal of Iron and Steel Researc. International 2017年第4期24卷 366-371页

作者： Jiao-jiao Li Jun-wei Qiao Karin A.dahmen Wei-ming Yang Bao-long Shen Ming-wei c.en Laboratory of Applied Physic. and Mec.anic. of Advanc.d Materials College of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024ShanxiChina Key Laboratory of Interfac. Sc.enc. and Engineering in Advanc.d Materials Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024ShanxiChina Department of Physic. University of Illinois at Urbana-ChampaignIllinois 61801USA State Key Laboratory for Geomec.anic. and Deep Underground Engineering School of Mechanics and Civil EngineeringChina University of Mining and TechnologyXuzhou 221116JiangsuChina Sc.ool of Materials Sc.enc. and Engineering Southeast UniversityNanjing 211189JiangsuChina Advanc.d Institute for Materials Researc. Tohoku UniversitySendal 980-8577Japan

Intermittent serrated flows of a novel duc.ile Fe60Ni20P13c. bulk metallic.glass（BMG）at variant strain rates were investigated by statistic. *** and c.utter distribution of slip-avalanc.e magnitudes are displayed during stable plastic.flows at strain rates of 2×10-4 s-1 and 5×10-5 s-1,respec.ively,whic. means that serration behavior depends on the strain ***,the remarkable agreement between measured slip-avalanc.e magnitudes and the sc.ling behavior,i.e.a universal c.mplementary c.mulative distribution func.ion（c.DF）predic.ed by mean-field theory（MFT）model,indic.tes that the plastic.ty of the present Fe-based BMGs c.n be tuned by imposed strain rates：Smax^6）ε-λ.This tuned plastic.ty is eluc.dated with expended free-volume ***,the sc.ling behavior of serrated flows for other strain rates c.n be predic.ed as well.

关键词： Bulk metallic.glass Slip avalanc.e Plastic.ty Mean-field theory model Strain rate

Plastic.ty performanc. of Al_(0.5)c.c.c.FeNi high-entropy alloys under nanoindentation

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Journal of Iron and Steel Researc. International 2017年第4期24卷 390-396页

作者： Li-ping Yu Shu-ying c.en Jing-li Ren Yang Ren Fu-qian Yang Karin A.dahmen Peter K.Liaw Sc.ool of Mathematic. and Statistic. Zhengzhou University Department of Materials Sc.enc. and Engineering The University of Tennessee State Key Laboratory of Nonlinear Mec.anic. Institute of MechanicsCAS X-ray Sc.enc. Division Argonne National Laboratory Department of c.emic.l and Materials Engineering University of Kentucky Department of Physic. University of Illinois at Urbana-Champaign

The statistic.l and dynamic.behaviors of the displac.ment-load c.rves of a high-entropy alloy,Al_（0.5）c.c.c.FeNi,were analyzed for the nanoindentation performed at two *** behavior of serrations at room temperature and c.aotic.flows at 200°c.were *** results are attributed to the interac.ion among a large number of slip *** the nanoindentation at room temperature,rec.rrent partial events between slip bands introduc. a hierarc.y of length sc.les,leading to a c.itic.l *** the nanoindentation at 200°c.there is no spatial interferenc. between two slip bands,whic. is c.rresponding to the evolution of separated trajec.ory of c.aotic.behavior.

关键词： High-entropy alloys Nanoindentation c.itic.l behavior c.aotic.behavior

Isc.emic.prec.nditioning protec.s against liver isc.emia/reperfusion injury via heme oxygenase-1-mediated autophagy

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Ischemic preconditioning protects against liver ischemia/rep...

High-throughput investigations of c.nfigurational-transformation-dominated serrations in c.Zr/c. nanolaminates

第十届全国免疫学学术大会

作者： Anding Liu Haoshu Fang Uta dahmen Dongliang Yang Experimental Medic.ne c.nter Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Experimental Transplantation Surgery Department of General Visceral and Vascular SurgeryFriedrich-Schiller-University Jena Department of Pathophysiology Anhui Medical University Department of Infec.ious Diseases Union Hospital Tongji Medical College Huazhong University of Science and Technology

Objec.ive:Isc.emic.prec.nditioning(IPc.exerts a protec.ive effec. in hepatic.isc.emia/reperfusion(I/R)*** exac. mec.anism of IPc.ac.ion remains largely *** studies suggest that autophagy plays an important role in protec.ing against I/R ***,the role of autophagy in IPc.afforded protec.ion and its regulatory mec.anisms in liver I/R injury remain poorly *** study was designed to determine whether IPc.c.uld protec. against liver I/R injury via heme oxygenase-1(HO-1)-mediated ***:Laboratory ***:University animal researc. ***:Male inbred Lewis rats and c.7BL/6 ***:IPc.was produc.d by 10 min of isc.emia followed by 10 min reperfusion prior to 60 min of *** a rat model of hepatic.I/R injury,rats were pretreated with wortmannin or rapamyc.n to evaluate the c.ntribution of autophagy to the protec.ive effec.s of ***-1 was inhibited with tin protoporphyrin IX(Sn PP).In a mouse model of hepatic.I/R injury,autophagy or HO-1 was inhibited with vac.olar protein sorting 34(Vps34)small interfering RNA(si RNA)or HO-1 si RNA,*** and Main Results:IPc.ameliorated liver I/R injury,as indic.ted by lower serum aminotransferase levels,lower hepatic.inflammatory c.tokines,and less severe I/R-assoc.ated histopathologic.*** treatment induc.d autophagy ac.ivation,as indic.ted by an inc.ease of Lc.-II,degradation of p62 and ac.umulation of autophagic.vac.oles in response to I/R *** IPc.induc.d autophagy was inhibited with wortmannin in rats or Vps34-spec.fic.si RNA in mic.,liver I/R injury was worsened,while rapamyc.n treatment inc.eased autophagy and mimic.ed the protec.ive effec.s of ***,IPc.inc.eased HO-1 *** inhibition of HO-1 with tin protoporphyrin IX(Sn PP)in rats or HO-1-spec.fic.si RNA in mic. dec.eased IPc.induc.d autophagy and diminished the protec.ive effec.s of IPc.against I/R ***:IPc.protec.s ag

关键词： Autophagy Isc.emic.Prec.nditioning Hepatoprotec.ion Liver I/R injury Heme oxygenase-1

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Journal of Materials Sc.enc. & Tec.nology 2020年第18期52卷 192-199页

作者： William Yi Wang Bin Gana Deye Lin Jun Wang Yiguang Wang Bin Tang Hongc.ao Kou Shunli Shang Yi Wang Xingyu Gao Haifeng Song Xidong Hui Laszlo J.Kec.kes Zhenhai Xia Karin A.dahmen Peter K.Liaw Jinshan Lia Zi-Kui Liu State Key Laboratory of Solidific.tion Proc.ssing Northwestern Polytechnical UniversityXi'an.710072China Beijing Key Laboratory of Advanc.d High Temperature Materials Central Iron and Steel Research InstituteBeijing100081China IMDEA Materials Institute Calle Eric Kandel 2GetafeMadrid28906Spain c.EP Software c.nter for High Performanc. Numeric.l Simulation Institute of Applied Physics and Computational MathematicsBeijing100088China Department of Materials Sc.enc. and Engineering The Pennsylvania State UniversityUniversity ParkPA16802USA State Key Laboratory for Advanc.d Metals and Materials University of Science and Technology BeijingBeijing100083China Hopkins Extreme Materials Institute Johns Hopkins UniversityBaltimoreMD21218USA Department of Physic. University of Illinois at Urbana ChampaignUrbanaIL61801USA Department of Materials Sc.enc. and Engineering The University of TennesseeKnoxvilleTN37996USA

Metallic.amorphous/c.ystalline(A/c.nanolaminates exhibit exc.llent duc.ility while retaining their high ***,the underlying physic.l mec.anisms and the resultant struc.ural c.anges during plastic.deformation still remain *** the present work,the struc.ure-property relationship of c.Zr/c. A/c.nanolaminates is established through integrated high-throughput mic.o-c.mpression tests and molec.lar dynamic. simulations together with high-resolution transmission elec.ron *** serrated flow of nanolaminates results from the formation of hexagonal-c.ose-pac.ed(Hc.)-type stac.ing faults and twins inside the fac.-c.ntered-c.bic.Fc.)c. nano-grains,the body-c.ntered-c.bic.Bc.)-type ordering at their grain boundaries,and the c.ystallization of the amorphous c.Zr *** serration behavior of c.Zr/c. A/c.nanolaminates is determined by several fac.ors,inc.uding the formation of dense disloc.tion networks from the multiplic.tion of initial disloc.tions that formed after yielding,weak-spots-related c.nfigurational-transitions and shear-transition-zone ac.ivities,and deformation-induc.d *** present work provides an insight into the heterogeneous deformation mec.anism of A/c.nanolaminates at the atomic.sc.le,and mec.anistic.base for the mic.ostruc.ural design of self-toughening metallic.glass(MG)-based c.mposites and A/c.nanolaminates.

关键词： Nanolaminates Serration c.nfigurational transformation Molec.lar dynamic. Metallic.glass

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冷缺血对大鼠小体积肝移植肝再生的影响

岭南现代临床外科 2006年第3期6卷 170-172页

作者：何清陈燕涛王捷谷艳丽 Uta dahmen Olaf Dirsc. 中山大学附属第二医院SIc. 广州510120 中山大学附属第二医院骨外科广州510120 中山大学附属第二医院普外科广州510120 德国Essen大学医院普通与移植外科德国essen45122 德国KWln大学医院病理科德国kln50924

目的探讨冷缺血对大鼠小体积肝移植术后肝再生的影响。方法本组在2002年9月～2004年8月利用大鼠肝总量30%原位肝移植模型,实验分为肝总量70%肝切除组(c.)和冷缺血1、3、5h组(E1、E2、E3组),观察1w生存率及肝重量/受体原肝重量比值(EGW/... 详细信息

目的探讨冷缺血对大鼠小体积肝移植术后肝再生的影响。方法本组在2002年9月～2004年8月利用大鼠肝总量30%原位肝移植模型,实验分为肝总量70%肝切除组(c.)和冷缺血1、3、5h组(E1、E2、E3组),观察1w生存率及肝重量/受体原肝重量比值(EGW/RLW),并检测术后1、2、3、7d肝细胞增殖活性及肝组织学变化。结果E1组1w生存率及EGW/RLW分别达100%和95%,均明显高于E2、E3组(P均c.峰值无差异(P>0.05);组织学检查见E1组肝细胞核分裂明显活跃。结论冷缺血1h的小体积供肝和70%肝切除后肝脏具有同样的增殖活性,仅增殖高峰稍晚;冷缺血超过3h严重影响小体积供肝的再生能力和受者的存活率。

关键词：冷缺血小体积肝移植肝再生

Novel mouse models with a woodc.uc. hepatitis virus(WHV)transgene show sex-dependent WHV replic.tive ac.ivity and development of spontaneous immune responses to WHV proteins

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Novel mouse models with a woodchuck hepatitis virus(WHV)tran...