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Sensitive humidity sensor based on moisture-driven energy generation

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Nano Research 2024年第6期17卷 5578-5586页

作者： Qingchao Ni Qing lou Chenglong Shen Guangsong Zheng Runwei Song Jingnan Hao Jialu Liu Jinyang Zhu Jinhao Zang Lin Dong Chong-Xin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Materials PhysicsMinistry of Educationand School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China State Centre for International Cooperation on Designer Low-Carbon&Environmental Materials and School of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China

The emergence of novel self-powered humidity sensors has attracted considerable attention in the fields of smart electronic devices and personal ***,self-powered humidity sensors have been fabricated using a moisture-driven energy generation(MEG)device based on asymmetric tubular graphitic carbon nitride(g-CN)films prepared on anodized aluminum(AAO)*** a relative humidity(RH)of 96%,the MEG device can provide an open-circuit voltage of 0.47 V and a short-circuit current of 3.51μA,with a maximum output power of 0.08μ*** inherent self-powered ability and humidity response via current variation,an extraordinary response of 1.78×106%(41%-96%RH)can be gained from the MEG *** possible power generation mechanism is that g-CN/AAO heterostructure can form ion gradient and diffusion under the action of moisture to convert chemical potential into electrical potential,evoking a connaturally sensitive response to ***-powered respiration monitoring device based on the sensor is designed to monitor human movement(sitting,warming up,and running)and sleep status(normal,snoring,and apnea),maintaining excellent stability during cumulative 12-h respiration *** self-powered humidity sensing technology has promising potential for extensive integration into smart electronic and round-the-clock health monitoring devices.

关键词： graphitic carbon nitride moisture-driven energy generation humidity sensor respiration monitoring

玉米须衍生磁性多孔碳的制备及其对海水中孔雀石绿的萃取

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分析测试学报 2020年第8期39卷 993-999页

作者：陈柏森王希越祝波连丽丽娄大伟吉林化工学院分析化学系吉林吉林132022

以可再生农业废弃物玉米须为碳前驱体,三氯化铁为铁源,通过溶剂热碳化法制备了表面负载Fe3O4纳米粒子的磁性水热碳材料(MHC),再以氢氧化钾(KOH)为化学活化剂,通过高温热解法成功制备了生物质衍生磁性多孔碳(AMC)。该磁性纳米复合材料具... 详细信息

以可再生农业废弃物玉米须为碳前驱体,三氯化铁为铁源,通过溶剂热碳化法制备了表面负载Fe3O4纳米粒子的磁性水热碳材料(MHC),再以氢氧化钾(KOH)为化学活化剂,通过高温热解法成功制备了生物质衍生磁性多孔碳(AMC)。该磁性纳米复合材料具有多孔结构,可为目标分析物提供大量的吸附位点,而均匀地分散在碳基质表面的铁氧化物(Fe3O4及Fe2O3)纳米粒子有助于吸附剂及负载分析物从水溶液中快速分离。AMC对孔雀石绿(MG)具有显著的吸附性能,最大吸附量可达312.5 mg/g。采用磁性固相萃取(MSPE)结合超高效液相色谱(UPLC)建立了水中MG的分析方法。优化了影响AMC萃取性能的关键因素,在100 mL pH 7.0的样品溶液中,使用6 mg AMC萃取20 min,以甲醇-乙醇(9∶1,体积比)作为洗脱液,可获得最佳萃取结果。该方法对0.05~5μg/L范围内的MG呈现良好的线性(r=0.999 6),其检出限为0.01μg/L,定量下限为0.03μg/L。使用AMC萃取加标海水样品中的MG,其回收率为104%~106%,RSD为1.7%~3.4%。该方法可用于养殖海水中MG的灵敏检测。

关键词：多孔碳磁分离孔雀石绿(MG) 磁性固相萃取(MSPE) 超高效液相色谱(UPLC)

Model informed precision medicine of Chinese herbal medicines formulas-A multi-scale mechanistic intelligent model

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Journal of Pharmaceutical Analysis 2024年第4期14卷 585-600页

作者： Yuanyuan Qian Xiting Wang Lulu Cai Jiangxue Han Zhu Huang Yahui lou Bingyue Zhang Yanjie Wang Xiaoning Sun Yan Zhang Aisong Zhu Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome Zhejiang Chinese Medical UniversityHangzhou310000China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing100190China Zhejiang Engineering Research Center for“Preventive Treatment”Smart Health of Traditional Chinese Medicine Zhejiang Chinese Medical UniversityHangzhou310000China College of Basic Medical Sciences Zhejiang Chinese Medical UniversityHangzhou310000China Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Shenyang110032China Academy of Chinese Medical Science Zhejiang Chinese Medical UniversityHangzhou310000China

Recent trends suggest that Chinese herbal medicine formulas(CHM formulas)are promising treatments for complex *** characterize the precise syndromes,precise diseases and precise targets of the precise targets between complex diseases and CHM formulas,we developed an artificial intelligence-based quantitative predictive algorithm(DeepTCM).DeepTCM has gone through multilevel model calibration and validation against a comprehensive set of herb and disease data so that it accurately captures the complex cellular signaling,molecular and theoretical levels of traditional Chinese medicine(TCM).As an example,our model simulated the optimal CHM formulas for the treatment of coronary heart disease(CHD)with depression,and through model sensitivity analysis,we calculated the balanced scoring of the ***,we constructed a biological knowledge graph representing interactions by associating herb-target and gene-disease ***,we experimentally confirmed the therapeutic effect and pharmacological mechanism of a novel model-predicted intervention in humans and *** novel multiscale model opened up a new avenue to combine“disease syndrome”and“macro micro”system modeling to facilitate translational research in CHM formulas.

关键词： Chinese herbal medicine formulas Precision medicine Mathematical modeling Systems biology Coronary heart disease Depression Ischemia-reperfusion Inflammation

Teaching Research on Integrating Ideological and Political Elements into Business English Reading Courses

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Journal of Contemporary Educational Research 2024年第4期8卷 101-107页

作者： Yanxia Xu Deping lou School of Foreign Language Harbin Cambridge UniversityHarbin 150086Heilongjiang ProvinceChina

In the current situation of economic globalization and communalization with a shared future for mankind,it is crucial to cultivate outstanding composite talents who possess morality,literacy,patriotism,business knowledge,good cross-cultural communication skills,and teamwork *** requires the Business English major to increase the reform of course *** article will propose several innovative paths for the ideological and political education of Business English Reading courses based on the necessity of conducting ideological and political education in Business English majors and working together with colleagues to study.

关键词： Business English Reading Curriculum ideological and political education Countermeasures

渤海湾盆地黄骅坳陷石炭系-二叠系煤系烃源岩生烃特征研究

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特种油气藏 2023年第4期30卷 19-27页

作者：王鑫李政朱日房黎萍王茹牛子铖楼达中国石化胜利油田分公司山东东营257000 国家能源页岩油研发中心山东东营257015 中国石油大港油田分公司天津300457

近年来,渤海湾盆地探明数个石炭系-二叠系煤系烃源岩供烃的凝析油气藏,展现出可观的勘探潜力。针对研究区烃源岩生烃特征认识不清、勘探方向不明的问题,亟需重新认识煤系烃源岩的供烃能力。为此,以渤海湾盆地黄骅坳陷为研究对象,通过岩... 详细信息

近年来,渤海湾盆地探明数个石炭系-二叠系煤系烃源岩供烃的凝析油气藏,展现出可观的勘探潜力。针对研究区烃源岩生烃特征认识不清、勘探方向不明的问题,亟需重新认识煤系烃源岩的供烃能力。为此,以渤海湾盆地黄骅坳陷为研究对象,通过岩心、测井、录井、试油等多元数据统计,基于盆地内构造单元沉积充填特征差异分析,运用盆地数值模拟技术建立沉积单元评价模型,开展黄骅凹陷煤系烃源岩不同岩层的空间展布、生烃潜力与生烃特征综合分析,明确了渤海湾盆地石炭系-二叠系煤系烃源岩生烃模式,并预测了研究区潜山油气有利聚集带。结果表明:黄骅坳陷石炭系-二叠系煤系烃源岩以煤岩为标志层,发育泥岩、炭质泥岩与煤岩3种生烃岩性,其中,泥岩厚度大,连续性强,生烃潜力大;生烃模拟表明,一次生烃以泥岩生油为主,二次生烃以多种烃源岩混合生油生气为主;发育早期沉降型、晚期沉降型与持续沉降型3类生烃模式,持续沉降型与晚期沉降型生烃区对潜山原地油气聚集最为有利。研究成果可为研究区煤系烃源岩供烃的油气成藏理论研究与勘探部署提供技术支撑。

关键词：煤系烃源岩生烃特征石炭系-二叠系黄骅坳陷渤海湾盆地

一种用PN码校正相控阵天线通道误差的新方法

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电讯技术 2014年第3期54卷 307-311页

作者：韩小娟何兵哲楼大年张宁中国空间技术研究院西安分院西安710100

为了校准相控阵天线通道间幅相误差,实现精确的数字波束形成,给出了一种用伪噪声序列(PN)码作为校准测试信号的在线校准方法(校准和通信可同时进行)。该方法由特定的校准站发送校准测试信号,被天线各阵元接收,并通过存在误差的各通道,... 详细信息

为了校准相控阵天线通道间幅相误差,实现精确的数字波束形成,给出了一种用伪噪声序列(PN)码作为校准测试信号的在线校准方法(校准和通信可同时进行)。该方法由特定的校准站发送校准测试信号,被天线各阵元接收,并通过存在误差的各通道,在接收端用与发端相同的PN码作为本地信号与接收信号逐通道做相关运算,对各通道的相关峰值做比较可求出校准矢量进而完成校准。仿真结果表明,该方法可以有效校准相控阵天线通道间的幅相误差,校准后的波束方向图接近理想的波束方向图。

关键词：相控阵天线数字波束形成幅相误差 PN码在线校准

黄骅坳陷石炭-二叠系凝析油气地球化学特征及来源分析

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吉林大学学报（地球科学版） 2020年第2期50卷 644-652页

作者：徐进军李宁金强刘吉华楼达滕建成中国石油大学(华东)地球科学与技术学院山东青岛266580 延长油田股份有限公司勘探开发技术研究中心陕西延安716001 中国石油大港油田勘探开发研究院天津300280

深层油气勘探是未来油气资源的重要接替领域。渤海湾盆地下伏石炭-二叠系煤系烃源岩自油气勘探取得新突破以来,一直是深层油气领域研究的热点。黄骅坳陷新部署的QG8井奥陶系碳酸盐岩储层和YG1井二叠系砂岩储层获高产凝析油气流,其来源... 详细信息

深层油气勘探是未来油气资源的重要接替领域。渤海湾盆地下伏石炭-二叠系煤系烃源岩自油气勘探取得新突破以来,一直是深层油气领域研究的热点。黄骅坳陷新部署的QG8井奥陶系碳酸盐岩储层和YG1井二叠系砂岩储层获高产凝析油气流,其来源判别问题是深层油气勘探的关键。针对QG8、YG1井凝析油气开展的生物标志化合物、有机碳稳定同位素和原油物性研究表明:两口井的凝析油均为低黏度、低密度的典型轻质原油,具有姥鲛烷优势(Pr/Ph>2.8),QG8井凝析油饱和烃δ13C为-29.1‰、芳烃δ13C为-26.8‰;天然气δ13C1偏重,介于-39.7‰^-36.4‰之间,干燥系数大于0.8,重烃可达16.2%,为偏干湿气。QG8与YG1井凝析油特征与黄骅坳陷石炭-二叠系煤系烃源岩(饱和烃δ13C为-29.26‰^-26.87‰,芳烃δ13C为-26.62‰^-24.15‰)及KG4井原油物性(0.757 1~0.840 2 g/cm^3)相近,天然气特征则相似于济阳坳陷GBG1井的煤成气(δ13C1为-43‰^-35‰),表明高产的凝析油气来自石炭-二叠系煤系烃源岩。证实渤海湾盆地深层石炭-二叠系煤系具有生烃潜力和油气勘探前景。

关键词：凝析油气油气地球化学油气源对比石炭-二叠系黄骅坳陷

Comparison of inebilizumab or rituximab in addition to glucocorticoid therapy for neuromyelitis optica spectrum disorders

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1073-1078页

作者： Chu-Yuan lou Yong Wang Jia-Yuan Xing Teng Ma Lei Tao Xiao-Tang Wang Run-Sheng Wang Neuroophthalmic Center Xi’an People’s Hospital(Xi’an Fourth Hospital)Xi’an 710004Shaanxi ProvinceChina

AIM:To investigate the short-term efficacy and safety of inebilizumab for neuromyelitis optica spectrum disorders(NMOSD).METHODS:A total of 33 patients with NMOSD treated with inebilizumab(Group INB,n=15)or rituximab(Group RTX,n=18)in addition to high-dose glucocorticoids were *** groups underwent hormone shock therapy during the acute ***,Group INB received inebilizumab injections during the remission phase,while Group RTX received rituximab injections.A comparison of aquaporins 4(AQP4)titer values,peripheral blood B lymphocyte counts,and visual function recovery was conducted before and 8wk after ***,adverse reactions and patient tolerability were analyzed after using inebilizumab treatment ***:Following inebilizumab treatment,there was a significantly improvement in the visual acuity of NMOSD patients(P0.05).Furthermore,inebilizumab exhibited higher safety levels than that of rituximab ***:The combination of inebilizumab and high-dose glucocorticoids proves to be *** comparison to rituximab injections,inebilizumab displays better tolerance and ***,it demonstrates a partial effect in preventing optic nerve ***,it stands as an effective method to reduce the disability rates and improve the daily living ability of patients with NMOSD.

关键词： neuromyelitis optica spectrum disorders inebilizumab rituximab glucocorticoids

Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress

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Chinese Journal of Integrative Medicine 2024年第5期30卷 398-407页

作者： JI Xiao-di YANG Ding CUI Xi-yuan lou Li-xia NIE Bo ZHAO Jiu-li ZHAO Ming-jing WU Ai-ming Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine Key Laboratory of Chinese Internal Medicine of Ministry of Education and BeijingBeijing 100700China Department of Traditional Chinese Medicine Fuwai HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100037China

Objective:To investigate the pharmacological mechanism of Qili Qiangxin Capsule(QLQX)improvement of heart failure(HF)based on miR133a-endoplasmic reticulum stress(ERS)***:A left coronary artery ligation-induced HF after myocardial infarction model was used in this *** were randomly assigned to the sham group,the model group,the QLQX group[0.32 g/(kg·d)],and the captopril group[2.25 mg/(kg·d)],15 rats per group,followed by 4 weeks of *** function such as left ventricular ejection fraction(EF),fractional shortening(FS),left ventricular systolic pressure(LVSP),left ventricular end diastolic pressure(LVEDP),the maximal rate of increase of left ventricular pressure(+dp/dt max),and the maximal rate of decrease of left ventricular pressure(–dp/dt max)were monitored by echocardiography and *** and eosin(HE)and Masson stainings were used to visualize pathological changes in myocardial *** m RNA expression of mi R133a,glucose-regulated protein78(GRP78),inositol-requiring enzyme 1(IRE1),activating transcription factor 6(ATF6),X-box binding protein1(XBP1),C/EBP homologous protein(CHOP)and Caspase 12 were detected by *** protein expression of GRP78,p-IRE1/IRE1ratio,cleaved-ATF6,XBP1-s(the spliced form of XBP1),CHOP and Caspase 12 were detected by Western *** T-mediated d UTP nick-end labeling(TUNEL)staining was used to detect the rate of ***:QLQX significantly improved cardiac function as evidenced by increased EF,FS,LVSP,+dp/dt max,-dp/dt max,and decreased LVEDP(Pdamage to some *** staining indicated that QLQX significantly reduced collagen volume fraction in myocardial tissue(P<0.01).Results from RT-PCR and Western blot showed that QLQX significantly increased the expression of mi R133a and inhibited the m RNA expressions of GRP78,IRE1,ATF6 and XBP1,as well as decreased the protein expressions of GRP78,cleave

关键词： heart failure Qili Qiangxin Capsule miR133a endoplasmic reticulum stress apoptosis