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Asian Journal of Andrology 2015年第3期17卷 481-486页

作者： da-Ke xiong Key Laboratory of Bio-Resources and Eco-Environment Ministry of Education School of Life Science Institute of Medical Genetics Sichuan University Chengdu China Bio-resource Research and Utilization Joint Key Laboratory of Sichuan and Chongqing Chengdu China Biotechnology Academy of Nanchuan Chongqing China

The reported effects of the glutathione S-transferase （GSTs） genes （GSTM1, GSTTI, and GSTP1） on male factor infertility have been inconsistent and even contradictory. Here, we conducted a case-control study to investigate the association between functionally important polymorphisms in GST genes and idiopathic male infertility. The study group consisted of 361 men with idiopathic azoospermia, 118 men with idiopathic oligospermia, and 234 age-matched healthy fertile male controls. Genomic DNA was extracted from the peripheral blood, and analyzed by polymerase chain reaction and restriction fragment length polymorphism analysis. There was a significant association between the GSTP1 variant genotype （lle/Val ＋ Val/Val） with idiopathic infertility risk （odds ratio [OR]： 1.53; 95% confidence interval [CI]： 1.11-2.11; P = 0.009）. Similarly, a higher risk of infertility was noted in individuals carrying a genotype combination of GSTTI-null and GSTP1 （lle/Val ＋ ValNal）（OR： 2.17; 95% Cl： 1.43-3.31; P = 0.0002）. These results suggest an increased risk of the GSTPI variant genotype （lle/Val ＋ Val/Val） for developing male factor infertility. Our findings also underrate the significance of the effect of GSTM1 and/or GSTT1 （especially the former） in modulating the risk of male infertility in males from Sichuan, southwest China.

关键词： genetic polymorphism glutathione S-transferase idiopathic infertility male factor

ON MAXIMA OF DUAL FUNCTION OF THE CDT SUBPROBLEM

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Journal of Computational Mathematics 2001年第2期19卷 113-124页

作者： xiong-da Chen Ya-xiang Yuan Reserach Development Center of Parallel Software Institute of SoftwareBeijing 100080China State Key Laboratory of Scientific and Engineering Computing Institute of Computational Mathematics and Ssientific/Engineering ComputingAcademy of Mathematics and Systems SciencesChinese Academy of SciencesBeijing 100080China

Focuses on a study which determined the geometry meaning of the maxima of the CDT mathematical subproblem's dual function. Properties of trust region subproblem; Approximation of the CDT feasible region; Relations bet... 详细信息

关键词： trust region subproblem global minimizer approximation

Solar-like and Mira-like oscillations of stars–A uniform excitation mechanism

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Research in Astronomy and Astrophysics 2013年第11期13卷 1269-1294页

作者： da-Run xiong Li-Cai Deng Purple Mountain Observatory Chinese Academy of Sciences Key Laboratory for Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences

Using a non-local and time-dependent theory of convection, we have cal- culated the linear non-adiabatic oscillations of the radial and low-degree F-p39 modes for evolutionary models from the main sequence to the asymptotic giant branch for stars with solar abundance （X = 0.70, Z = 0.02） in the mass range of 0.6-3.0 3//o. The results show that iow luminosity cool stars tend to be solar-like oscillators, whose low-order modes are stable, but intermediate and high order p-modes are pulsationally unstable; their unstable modes have a wide range in frequency and small values for amplitude growth rates. For stars with increasing luminosity and therefore lower tem- perature, the unstable modes shift towards lower orders, the corresponding range of frequency decreases, and the amplitude growth rate increases. High luminosity red gi- ant stars behave like typical Mira-like oscillators. The effects of the coupling between convection and oscillations on pulsational instability have been carefully analyzed in this work. Our research shows that convection does not simply act as a damping mechanism for oscillations, and the complex nature of the coupling between convec- tion and oscillations makes turbulent convection sometimes behave as damping, and sometimes as excitation. Such a picture can not only naturally account for the red edge of the instability strip, but also the solar-like oscillations in low luminosity red stars and Mira-like ones in high luminosity red giants.

关键词： convection--stars: oscillations- stars: late-type- stars: evolution

A new method of immobilizing ionic liquids into layered zirconium phosphates

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Chinese Chemical Letters 2007年第6期18卷 764-767页

作者： Hai Yan Wang da xiong Han The Key Laboratory of Global Change and Marine-Atmopheric Chemistry Third Institute of Oceanography of State Oceanic AdministrationXiamen 361005China Department of Pharmacy Medical College of Xiamen UniversityXiamen 361005China

In this work, a new method of a series of ion liquids (ILs) 1-alkyl-3-methylimidazolium chloride [Cnmim]Cl (n = 2, 4, 6, 8) intercalation into layered zirconium phosphates was investigated. It was found that the α-ZrP·2BA (i.e. pre-intercalated BA was arranged in a bilayer mode in the galleries of α-ZrP) was a suitable host for intercalation ILs: ILs was inserted through exchanging pre-intercalated BA. And the intercalation orientation was investigated by use of X-ray diffraction (XRD) experiments and molecular modeling calculation.

关键词： Ionic liquids Zirconium phosphates Intercalation

Functional switching of ATM:sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells

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Chinese Journal of Cancer 2012年第8期31卷 364-372页

作者： Yan Li Hua xiong da-Qing Yang The Hormel Institute University of MinnesotaAustinMN 55912USA

Ataxia-telangiectasia(A-T) is an autosomal recessive disorder characterized by cerebellar ataxia and oculocutaneous *** gene mutated in this disease,ATM(A-T,mutated),encodes a 370-kda Ser/Thr protein *** not only mediates cellular response to DNA damage but also acts as an activator of Akt in response to ***,despite intensive studies,the mechanism underlying the neuronal degeneration symptoms of human A-T is still poorly *** found that the topoisomerase inhibitors etoposide and camptothecin readily induced apoptosis in undifferentiated proliferating SH-SY5Y cells but could not induce apoptosis in neuronally differentiated SH-SY5Y *** addition,etoposide induced p53 phosphorylation and H2AX foci formation in proliferating SH-SY5Y cells but failed to do so in differentiated SH-SY5Y ***,while inhibition of ATM in undifferentiated SH-SY5Y cells partially protected them from etoposide-induced apoptosis,the same treatment had no effect on cell viability in differentiated SH-SY5Y *** results suggest that DNA damage or defective response to DNA damage is not the cause of neuronal cell death in human *** contrast,we discovered that Akt phosphorylation was inhibited when ATM activity was suppressed in differentiated SH-SY5Y ***,inhibition of ATM induced apoptosis following serum starvation in neuronally differentiated SH-SY5Y cells but could not trigger apoptosis under the same conditions in undifferentiated proliferating SH-SY5Y *** results demonstrate that ATM mediates the Akt signaling and promotes cell survival in neuron-like human SH-SY5Y cells,suggesting that impaired activation of Akt is the reason for neuronal degeneration in human A-T.

关键词：神经元样细胞 DNA损伤细胞增殖 ATM Akt SH-SY5Y细胞人类有丝分裂

Boundedness of Solutions of Quasi-periodic p-Laplacian Equations with Jumping Nonlinearity

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Acta Mathematica Sinica,English Series 2023年第1期39卷 176-192页

作者： Xin Li ZHANG Ya Qun PENG da xiong PIAO School of Mathematics and Physics Qingdao University of Science and TechnologyQingdao 266061P.R.China School of Mathematics(Zhuhai) Sun Yat-sen UniversityZhuhai 519082P.R.China School of Mathematical Sciences Ocean University of ChinaQingdao 266100P.R.China

In this article,we prove the existence of quasi-periodic solutions and the boundedness of all solutions of the p-Laplacian equation(φ_(p)(x’))’+aφ_(p)(x+)-bφ_(p)(x-)=g(x,t)+f(t),where g(x,t)and f(t)are quasi-periodic in t with Diophantine frequency.A new method is presented to obtain the generating function to construct canonical transformation by solving a quasi-periodic homological equation.

关键词： Quasi-periodic twist mapping invariant curve boundedness p-Laplacian

On the effect of turbulent anisotropy on pulsation stability of stars

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Research in Astronomy and Astrophysics 2017年第3期17卷 77-86页

作者： Chun-Guang Zhang Li-Cai Deng da-Run xiong Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

Within the framework of a non-local time-dependent stellar convection theory, we study in detail the effect of turbulent anisotropy on stellar pulsation stability. The results show that anisotropy has no substantial influence on pulsation stability of g modes and low-order （radial order nr 〈 5） p modes. The effect of turbulent anisotropy increases as the radial order increases. When turbulent anisotropy is neglected, most high-order （nr 〉 5） p modes of all low-temperature stars become unstable. Fortunately, within a wide range of the anisotropic parameter c3, stellar pulsation stability is not sensitive to the specific value of ca. Therefore it is safe to say that calibration errors of the convective parameter ca do not cause any uncertainty in the calculation of stellar pulsation stability.

关键词： convection- stars: interiors - stars: oscillations

Layered zirconium phosphate-supported metalloporphyrin:Synthesis and catalytic application

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Chinese Chemical Letters 2008年第11期19卷 1330-1332页

作者： Hai Yan Wang Wei Dong Ji da xiong Han The Third Institute of Oceanography of State Oceanic Administration Xiamen 361005 China Department of Pharmacy Medical College of Xiamen University Xiamen 361005 China

This paper reports a new route for the preparation of layered alpha-zirconium phosphate （α-ZrP）-supported metalloporphyrin MnTMPyP. MnTMPyP was intercalated into α-ZrP using α-*** （i.e. pre-intercalated bultylamine was arranged by a monolayer mode in α-ZrP） as a starting material. The catalytic activity of the supported material for homovanillic acid （HVA） oxidation was investigated. The results showed a promising layered material-supported catalyst in catalytic system.

关键词： MnTMPyP Intercalation Layered α-ZrP Catalysis Supported material

Analysis of Distributed Phase Shift in Distributed Feedback Semiconductor Lasers

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Chinese Physics Letters 1999年第10期16卷 721-722页

作者： SHEN dan-xun GU Wan-yi XU da-xiong Institute of Optical Communication Beijing University of Posts and TelecommunicationsBeijing 100876

A new algorithm based on a transfer matrix method is given to analyze a new distributed feedback(DFB)structure-distributed phase shift in DFB *** the small signal analysis,a new model is presented with this *** withλ/4 phase-shifted DFB and three phase shifted DFB lasers,this structure shows superior characteristics in both static and dynamic behavior.

关键词： Lasers structure phase

On the Red Edge of the δ Scuti Instability Strip

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Chinese Journal of Astronomy and Astrophysics 2002年第5期2卷 441-448页

作者： Yan Xu Zhi-Ping Li Li-Cai Deng da-Run xiong National Astronomical Observatories Chinese Academy of SciencesBeijing 100012 Department of Physics Tianjin Normal UniversityTianjin 300073 Purple Mountain Observatory Chinese Academy of SciencesNanjing 210008

The δ Scuti star catalogue is used to derive the observational locations of such stars on the HR diagram. The theoretical and observational instability strips are compared to check the theoretical red edge obtained by considering nonlocal time-dependent convection theory. The observational instability strip almost overlaps with the theoretical one, but the observed blue and red envelopes are hotter than the theoretical edges. The distribution of δ Scuti stars in the pulsation strip is not uniform.

关键词： stars: variables: δ Sct - stars: oscillations ?stars: HR diagram