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Incidence and mortality of corpus uteri cancer in China,2008-2012

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Chinese Journal of Cancer Research 2019年第3期31卷 435-442页

作者： Yunfeng xi Wenrui Wang Wenjie Chen Ke Han Liying Qiao Wanqing Chen Inner Mongolia Integrative Center for Disease Control and Prevention Hohhot 010031China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Science & Peking Union Medical CollegeBeijing 100021China

Objective: To analyze the incidence and mortality rates of corpus uteri cancer in China using 2008-2012 data from the National Central Cancer Registry(NCCR) of ***: We analyzed 2008-2012 data from 135 cancer registries using NCCR screening methods and *** Chinese standard population in 2000 and Segi’s world population were applied to determine age-standardized incidence and mortality rates. The annual percentage change(APC) in rate was calculated using the Joinpoint Regression ***: The crude incidence of corpus uteri cancer was 9.58/100,000, making corpus uteri cancer the ninth most common malignancy in females. The crude mortality was 2.97/100,000, making corpus uteri cancer the 13 th leading cause of death from malignant tumors in females. The incidence was higher in urban than in rural areas, but the mortality was higher in rural than in urban areas. The crude incidence was higher in eastern areas than in middle and western areas, while the crude mortality was higher in middle areas than in eastern and western *** 2003-2012, the age-standardized incidence rate based on the Chinese standard population in 2000(ASIRC)with uterine cancer increased significantly by 3.0% annually, while the age-standardized mortality rate based on the Chinese standard population in 2000(ASMRC) decreased by 0.4% annually, but the decrease was not statistically significant. The APC in incidence rate in the age groups of 30-44 years was 4.2%, which was statistically significant;increases/decreases in other age groups were not statistically significant. From 2003 to 2004, the age groups of 60-74 years showed high incidence, while from 2005 to 2012, the age groups of 45-59 years had high ***: The incidence and mortality rates of corpus uteri cancer in China from 2008 to 2012 were relatively low compared with other countries. However, the significant increase in incidence rates and marked decrease in patient age suggest the need to st

关键词： China corpus uteri cancer incidence mortality

Changes of optic nerve head microcirculation in high myopia

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International Journal of Ophthalmology(English edition) 2023年第1期16卷 102-107页

作者： Wen-Quan Tang Yu-Lin Luo xi-Lang Wang Xuan-Chu Duan Department of Ophthalmology Hunan Children’s HospitalChangsha 410007Hunan ProvinceChina Changsha Aier Eye Hospital Changsha 410011Hunan ProvinceChina Aier School of Ophthalmology Central South UniversityChangsha 410011Hunan ProvinceChina

AIM:To analyze the correlation of age,spherical equivalent(SE),and axial length(AL)with the microcirculation of optic nerve head(ONH)in high myopia(HM).METHODS:In this cross-sectional clinical study,164 right eyes were *** coherence tomography angiography(OCTA)was used to detect ONH vessel *** were classified based on age,SE,and *** of Age1,Age2,and Age3 were denoted for age classification(Age10.05)and the SE1,SE2,and SE3 groups(all P>0.05).No significant difference was observed in the intrapapillary vascular density(IVD)among AL1,AL2,AL3,and AL4 groups(P>0.05).However,a significant decrease was found in the peripapillary vascular density(PVD)in the AL1,AL2,AL3,and AL4 groups(F=3.605,P=0.015),especially in the inferotemporal(IT;F=6.25,P0.05).The PVD was correlated with AL(r=-0.236,P0.05).CONCLUSION:With the increase of AL,the IVD remains stable while the PVD decreases,especially in the three directions of temporal(IT,TI,and TS).The main cause of microcirculation reduction may be related to AL elongation rather than an increase in age or SE.

关键词： high myopia optic nerve head optical coherence tomography angiography vascular density axial length

Quantitative method for analysis of tobacco-specific N-nitrosamines in mainstream cigarette smoke by using heart-cutting two dimensional liquid chromatography–tandem mass spectrometry

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Quantitative method for analysis of tobacco-specific N-nitro...

Photocatalytic degradation investigation of dicofol

中国烟草学会2017年学术年会

作者：陈敏 Leijun Wang Huizhong Dong xi Shao da Wu Baizhan Liu xiangmin Zhang Chaoying Chen Department of Chemistry Fudan University Technology Center Shanghai Tobacco Group Co. Ltd.

A heart-cutting two dimensional liquid chromatography coupled with tandem mass spectrometry method was developed for the analysis of tobacco-specific nitrosamines at low concentration level in Virginia type cigarette smoke. A strong cation exchange column was utilized for the first dimensional separation, which effectively removed acidic and neutral components in the smoke, followed by a reversed phase liquid chromatography coupled with tandem mass spectrometric analysis. To capture components of the tobacco-specific nitrosamines in the effluent on the trapping column, a compensating pump was applied for on-line dilution and p H adjustment during the period of the tobacco-specific nitrosamines fraction transferring and enrichment. High sensitive determination of the tobacco-specific nitrosamines in mainstream cigarette smoke was achieved by isotope deuterated internal standards under the multiple reaction monitoring mode. Compared with traditional methodologies, the method was almost no matrix interference. Limits of quantity for the tobacco-specific nitrosamines were within 0.027 - 0.094 ng/mL. And the results showed good reproducibility and accuracy. Finally, the new method was applied to analysis of the Kentucky reference cigarettes and the results agreed well with joint experiments of Cooperation Centre for Scientific Research Relative to Tobacco.

关键词： Mainstream cigarette smoke/Tobacco-specific N-nitrosamines/Two dimensional liquid chromatography/Heart-cutting

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Chinese Science Bulletin 2008年第1期53卷 27-32页

作者： YU BinBin ZENG JingBin GONG LiFen YANG xiaoQing ZHANG LiMei CHEN xi Department of Chemistry and Key Laboratory of Analytical Sciences of Ministry of Education College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China State Key Laboratory of Marine Environmental Science Xiamen University Xiamen 361005 China College of Foreign Languages and Cultures Xiamen University Xiamen 361005 China College of Chemistry and Life Sciences Normal Institute of Quanzhou Quanzhou 362000 China

Photocatalytic degradation of dicofol was investigated on TiO2 nano particles (TiO2-NPs) under UV light irradiation. It was shown that dicofol could be completely degraded into inorganic chloride ion under the condition of 0.25 mg/mL TiO2-NPs, 2 h irradiation of 400 W high pressure mercury lamp with a wavelength of 365 nm and air at a rate of 100 mL/min. The effects of the experimental conditions, in-cluding the amount of TiO2-NPs, irradiation time and the intensity of light, were studied. The apparent photodegradation rate constant was 0.167/min under the optimal condition. The photocatalytic degra-dation mechanism of dicofol was also discussed.

关键词：纳米材料二氧化钛光辐照光强度

Construction of almost optimal resilient Boolean functions via concatenating Maiorana-McFarland functions

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Science China(Information Sciences) 2011年第4期54卷 909-912页

作者： ZHANG WeiGuo & xiAO GuoZhen ISN Laboratory,xidian University,xi’an 710071,China 1. ISN Laboratory Xidian University Xi’an 710071 China

We describe a method to construct an n-variable (n even) almost optimal resilient Boolean function via concatenating 2 d properly chosen (n-d)-variable Maiorana-McFarland *** an example,a 5-resilient 42-variable Boole... 详细信息

关键词： Boolean functions nonlinearity resiliency stream ciphers

Validity and Reliability of the Wristband Activity Monitor in Free-living Children Aged 10-17 Years

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Biomedical and Environmental Sciences 2019年第11期32卷 812-822页

作者： YANG xi JAGO Russell ZHANG Qian WANG Yu Ying ZHANG Jian ZHAO Wen Hua National Institute for Nutrition and Health Chinese Center for Disease Control and PreventionBeijing 100050China Chinese Center for Disease Control and Prevention Beijing 102206China Center for Exercise Nutrition and Health SciencesSchool for Policy StudiesUniversity of BristolBristolBS81 TZUK

Objective In this study we aimed to examine the reliability and validity of the wristband activity monitor against the accelerometer for *** A total of 99 children(mean age = 13.0 ± 2.5 y) wore the two monitors in a free-living context for 7 days. Reliability was measured by intraclass correlation to evaluate consistency over ***-measures analyses of variance was used to detect differences across days. Spearman’s correlation coefficient(rho), median of absolute percentage error, and Bland-Altman analyses were performed to assess the validity of the wristband against the Acti Graph accelerometer. The optimal number of repeated measures for the wristband was calculated by using the Spearman-Brown prophecy *** The wristband had high reliability for all variables, although physical activity data were different across 7 days. A strong correlation for steps(rho: 0.72, P < 0.001), and moderate correlations for time spent on total physical activity(rho: 0.63, P < 0.001) and physical activity energy expenditure(rho: 0.57, P < 0.001) were observed between the wristband and the accelerometer. For different intensities of physical activity, weak to moderate correlations were found(rho: 0.38 to 0.55, P < 0.001).Conclusion The wristband activity monitor seems to be reliable and valid for measurement of overall children’s physical activity, providing a feasible objective method of physical activity surveillance in children.

关键词： Physical activity Measurement Children Wristband activity monitor

A novel gene R049 identified in uropathogenic Escherichia coli provides partial protection in mice from colonization

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Chinese Science Bulletin 2011年第8期56卷 755-761页

作者： CHEN JinYing GE xin ZHANG YuMei LIN Xu ZHANG Wei YANG xi Department of Medical Microbiology Tianjin Medical University Tianjin 300070 China Research Center of Molecular Medicine Fujian Medical University Fuzhou 350004 China Department of Medical Microbiology Faculty of Medicine University of Manitoba Winnipeg Manitoba R3E OW3 Canada

Uropathogenic Escherichia coli(UPEC) is the most common causative organism of human urinary tract infection(UTI).Several UPEC virulence factors have been identified,but more are yet to be *** previously identified a novel 789-bp-long DNA fragment(named R049) in UPEC strain 132 using a suppressive subtractive hybridization *** the present study,we used genome walking to elongate the sequence of this fragment to obtain the whole gene sequence and examined the role of this gene product in generating protective *** bioinformatic analysis,we predicted that this gene is a 1311-bp open reading frame(ORF),which we designated ORFR049(GenBank accession No.:EF488001).We further constructed a prokaryotic expression system to express full recombinant R049 protein and isolated and purified the protein through IPTG induction and nickel affinity *** mouse immunosera generated by the purified protein,we confirmed the natural expression and outer membrane localization of the protein in wild-type strain UPEC132 by Western *** test the potential of this protein as a vaccine candidate,we immunized mice with the recombinant protein before challenging them with UPEC132 through the urinary *** results showed significantly reduced bacterial colonization in the urine and kidneys of the immunization group compared with the control ***,the degree of renal pathological damage was not significantly improved in the immunized *** study has identified a novel gene of UPEC which can generate protective immunity against *** novel gene provides a promising new vaccine candidate.

关键词：保护性免疫免疫小鼠大肠杆菌基因组肾炎定植抑制消减杂交技术 GenBank

U-shaped Vision Transformer and Its Application in Gear Pitting Measurement

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Journal of Dynamics, Monitoring and Diagnostics 2022年第4期1卷 223-228页

作者： Sijun Wang Yi Qin Dejun xi Chen Liang College of Mechanical and Vehicle Engineering Chongqing UniversityChongqingChina

Although convolutional neural networks have become the mainstream segmentation model,the locality of convolution makes them cannot well learn global and long-range semantic *** further improve the performance of segmentation models,we propose U-shaped vision Transformer(UsViT),a model based on Transformer and ***,residual Transformer blocks are designed in the encoder of UsViT,which take advantages of residual network and Transformer backbone at the same *** is more,transpositions in each Transformer layer achieve the information interaction between spatial locations and feature channels,enhancing the capability of feature *** the decoder,for enhancing receptive field,different dilation rates are introduced to each convolutional *** addition,residual connections are applied to make the information propagation smoother when training the *** first verify the superiority of UsViT on automatic portrait matting public dataset,which achieves 90.43%accuracy(Acc),95.56%Dice similarity coefficient,and 94.66%Intersection over Union with relatively fewer ***,UsViT is applied to gear pitting measurement in gear contact fatigue test,and the comparative results indicate that UsViT can improve the Acc of pitting detection.

关键词： vision Transformer residual connection dilation rate information interaction pitting measurement

Effect of Powder Particle Size on Microstructure and Mechanical Property of Ni-Based P/M Superalloy Product

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Journal of Iron and Steel Research International 2003年第3期10卷 71-74页

作者： ZHANG Ying ZHANG Yi-wen ZHANG Feng-ge TAO Yu CHEN xi-chun Central Iron and Steel Research Institute

The solid sintering behavior and mechanical properties of Fe Ni powders prepared by mechanical alloying of elemental powders and hot pressing sintering in vacuum atmospheres were investigated. It was observed that the microstructure of the powder particles evolves in three stages. The alloy powder with average grain size of 20-30 nm was obtained. The sinter densification depends crucially on the particle rearrangement and the large amount of internal strain introduced during milling. The theoretical density of over 95 % was obtained after hot pressing sintering at 800 ℃ for 30 min with pressure of 50 MPa. No significant grain growth was observed during sintering. And also relatively high hardness was obtained.

关键词： mechanical alloying nanostructured material mechanical property hot pressing sintering