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健身游戏、认知训练与老年人跌倒

中国康复 2024年第9期39卷 566-566页

作者：苏浩(译) 中国医科大学附属盛京医院

跌倒是全世界老年人意外受伤导致死亡的第二大原因。强有力的证据表明,运动,特别是平衡训练可以防止老年人跌倒。这项研究测试了smart±step家用电脑游戏系统,其中有8个游戏可以在坐着时使用触控板(认知训练)或通过踩在踏板上的目标面板... 详细信息

跌倒是全世界老年人意外受伤导致死亡的第二大原因。强有力的证据表明,运动,特别是平衡训练可以防止老年人跌倒。这项研究测试了smart±step家用电脑游戏系统,其中有8个游戏可以在坐着时使用触控板(认知训练)或通过踩在踏板上的目标面板(健身游戏训练)来进行。研究对象为769名社区老年人,他们被随机分为三组:认知训练组(CT)、电脑垫上的运动训练组(EST)和收到一本有关健康衰老及预防跌倒的教育小册子的对照组。

关键词：认知训练平衡训练意外受伤老年人跌倒预防跌倒家用电脑训练组健身

Impact of mycotoxins and their metabolites associated with food grains

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Grain & Oil Science and Technology 2023年第1期6卷 1-9页

作者： Chennappa Gurikar d.P.Shivaprasad Luis Sabillón N.A.Nanje Gowda Kaliramesh Siliveru Ramaiah University of Applied Sciences BangaloreIndia department of Grain Science and Industry Kansas State UniversityManhattanKSUSA department of Family and Consumer Sciences New Mexico State UniversityLas CrusesNMUSA

Mycotoxins are secondary toxic metabolites synthesized by numerous filamentous fungi including members of the genus Fusarium,Penicillium,drechslera,Aspergillus,Claviceps,Monascum,Alternaria,Cephalosporium,Nigrospora,and *** them,Aspergillus and Fusarium species are major plant pathogens recognized to induce infection and produce mycotoxins in food *** than 400 mycotoxins have been documented and among them,aflatoxin,fumonisins,trichothecenes,zearalenone,ochratoxin A,citrinin,ergot alkaloids,and patulin are the most prominent compounds linked to a variety of human and animal health *** Fusarium and Aspergillus belong to a saprophytic group,which can infect and contaminate many crops at pre and post-harvest *** can have a variety of negative effects on health in both humans and *** and their metabolites can cause severe acute poisoning,which can result in death,as well as long-term negative health effects,such as cancer and immune-suppressive disorders in living beings(animals and humans).Mycotoxin contamination of agricultural goods has gained global significance,due to its toxic effects on living beings,as well as its importance to international *** objective is to provide a consolidated information on the potential mycotixs in food grains and their significant impact on the health of the human beings.

关键词： Mycotoxins Aspergillus Fusarium Penicillium Carcinogen Contamination Aflatoxins Fumonisins

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BIM技术在桥梁工程设计阶段的应用研究

北京交通大学学报 2015年第6期39卷 80-84页

作者：刘智敏王英孙静贾英杰高日北京交通大学土木建筑工程学院北京100044 中国中铁七局集团有限公司郑州450000

利用BIM技术对塞拉利昂公路中的一座桥梁在设计阶段的应用进行研究,完成了项目的建模、设计检查,工程量清算,生成二维施工图以及施工模拟等工作.项目在桥梁族建库,出图模板设置以及4d施工模拟等方面开展了研究,开发了运维测试数据接口.... 详细信息

利用BIM技术对塞拉利昂公路中的一座桥梁在设计阶段的应用进行研究,完成了项目的建模、设计检查,工程量清算,生成二维施工图以及施工模拟等工作.项目在桥梁族建库,出图模板设置以及4d施工模拟等方面开展了研究,开发了运维测试数据接口.研究结果表明BIM技术可以实现项目设计阶段的可视化展示,大幅提高施工图纸量,提升设计效率,达到控制项目成本并缩短工期的目的,项目为BIM技术在桥梁工程设计和全生命周期维护方面的应用及推广积累了经验.

关键词： BIM技术桥梁设计施工模拟数据监测

长春市儿童医院1998～2001年轮状病毒哨点监测分析

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中华流行病学杂志 2003年第11期24卷 1010-1012页

作者：孙利炜童志礼李丽红章菁陈琦郑丽舒刘静谢华萍王承训张丽杰 Ivanoff B Glass ri Bresee JS Jiang XI Kilgore PE 方肇寅长春市儿童医院 130061 中国疾病预防控制中心病毒病预防控制所 department of Vaccines and Biologicals WHO Viral Gastroenteritis Section Children’s Hospital Medical Center Cincinnati International Vaccine Institute Seoul

目的　为在中国开发和应用轮状病毒疫苗提供流行病学背景资料。方法　以医院为基础的哨点监测 ,在长春市儿童医院 5岁以下腹泻患儿中进行 ,收集患儿临床资料和粪便标本 ,轮状病毒检测用聚丙烯酰胺凝胶电泳 (PAGE)和或酶联免疫吸附试验... 详细信息

目的　为在中国开发和应用轮状病毒疫苗提供流行病学背景资料。方法　以医院为基础的哨点监测 ,在长春市儿童医院 5岁以下腹泻患儿中进行 ,收集患儿临床资料和粪便标本 ,轮状病毒检测用聚丙烯酰胺凝胶电泳 (PAGE)和或酶联免疫吸附试验 (ELISA) ,毒株分型用ELISA和或逆转录聚合酶链反应 (RT PCR)。所有资料录入计算机进行数据分析。结果　 3年监测中共调查 2 3 4 3例腹泻患儿 ,收集便样 12 11份 ,轮状病毒检出率门诊患儿和住院患儿分别为 3 1.0 %和 52 .9%。轮状病毒感染 95.0 %发生于 2岁以下儿童。每年寒冷季节流行 (11月到次年 3月 )。流行的轮状病毒G血清型依次为G1(82 .4% )、G2 (5.0 % )、G3 (3 .3 % )和G 4(0 .9% ) ,P基因型以P[8]和P[4]为常见。共检出 9种P～G结合的毒株 ,其中世界常见的 4种流行株占 75.6%。结论　轮状病毒流行毒株呈现超常多样性。

关键词：长春市儿童医院 1998~2001年轮状病毒监测流行病学腹泻

α-Fe〈110〉倾斜晶界上He扩散机理的分子动力学研究

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原子能科学技术 2012年第5期46卷 513-519页

作者：贺新福 d.Terentyev 杨文中国原子能科学研究院反应堆工程研究设计所北京102413 比利时核研究中心比利时B-2400

采用分子动力学结合Juslin等最近建立的Fe-He原子间相互作用势函数研究了300～1 200K范围内α-Fe中具有不同位相差(26°～140°)的〈110〉倾斜晶界的热稳定性、He在各晶界上的结合能及其晶界扩散模式,计算了间隙He在晶界上的扩散系数。... 详细信息

采用分子动力学结合Juslin等最近建立的Fe-He原子间相互作用势函数研究了300～1 200K范围内α-Fe中具有不同位相差(26°～140°)的〈110〉倾斜晶界的热稳定性、He在各晶界上的结合能及其晶界扩散模式,计算了间隙He在晶界上的扩散系数。研究结果表明:1 200K以下各晶界均具有良好的热稳定性;He与晶界具有很强的结合能;间隙He在不同类型晶界上具有不同的扩散机制,间隙He在晶界上的扩散模式取决于晶界的原子结构及晶界上自由空间的大小。

关键词： α-Fe 〈110〉倾斜晶界热稳定性 He扩散分子动力学

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香栓菌的驯化栽培及生物学发育特征

菌物学报 2019年第2期38卷 187-194页

作者：马列包海鹰韩玉胡日瓦图力古尔李玉吉林农业大学药用菌物资源及开发利用重点研究室吉林长春130118 吉林农业大学食药用菌教育部工程研究中心吉林长春130118

为了筛选香栓菌Trametes suaveolens的最佳出菇配方,同时对子实体不同生长阶段的生物学发育特征进行研究。本文用杨树、柳树、秸秆木屑作为培养料设置了8种配比,每种分为对照A、测试组B共计16个配方进行筛选,对不同时期的菌丝发育状况... 详细信息

为了筛选香栓菌Trametes suaveolens的最佳出菇配方,同时对子实体不同生长阶段的生物学发育特征进行研究。本文用杨树、柳树、秸秆木屑作为培养料设置了8种配比,每种分为对照A、测试组B共计16个配方进行筛选,对不同时期的菌丝发育状况进行显微观察。结果柳树木屑、杨树木屑的配方均能成功栽培出香栓菌子实体,开袋后在90%–95%空气湿度、一定散射光、13–18℃的低温刺激下28d原基发育为菇蕾,继续培养28d后子实体成熟。其中配料为柳树木屑97%、蔗糖1%、石灰1%、石膏1%、含水量65%左右的配方出菇率最高,配料为柳树木屑的配方开袋后子实体长势最佳,采用边缘开袋方式最佳。子实体发育过程中,先分化出白色蜂窝状原基,原基依靠孔状结构吸收营养后,在其上层包被形成黑色菇蕾,同时基部开始形成子实层;菇蕾内部生殖菌丝不断分化和发育,体积逐渐膨大,颜色由深变浅,菌丝分化出担子并产生担孢子,最终形成子实体。

关键词：香栓菌驯化栽培显微结构子实体

Visualization and selection of dynamic Mode decomposition components for unsteady flow

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Visual Informatics 2021年第3期5卷 15-27页

作者： T.Krake S.Reinhardt M.Hlawatsch B.Eberhardt d.Weiskopf Visualization Research Center(VISUS) Allmandring 1970569 StuttgartGermany Hochschule der Medien Nobelstraße 1070569 StuttgartGermany

dynamic Mode decomposition(dMd)is a data-driven and model-free decomposition *** is suitable for revealing spatio-temporal features of both numerically and experimentally acquired ***,dMd performs a low-dimensional spectral decomposition of the data into the following components:the modes,called dMd modes,encode the spatial contribution of the decomposition,whereas the dMd amplitudes specify their *** associated eigenvalue,referred to as dMd eigenvalue,characterizes the frequency and growth rate of the dMd *** this paper,we demonstrate how the components of dMd can be utilized to obtain temporal and spatial information from time-dependent flow *** begin with the theoretical background of dMd and its application to unsteady ***,we examine the conventional process with dMd mathematically and put it in relationship to the discrete Fourier *** analysis shows that the current use of dMd components has several *** resolve these problems we adjust the components and provide new and meaningful insights into the decomposition:we show that our improved components capture the spatio-temporal patterns of the flow ***,we remove redundancies in the decomposition and clarify the interplay between components,allowing users to understand the impact of *** new representations,which respect the spatio-temporal character of dMd,enable two clustering methods that segment the flow into physically relevant sections and can therefore be used for the selection of dMd *** a number of typical examples,we demonstrate that the combination of these techniques allows new insights with dMd for unsteady flow.

关键词： dynamic Mode decomposition Spectral decomposition

drugs for Non-alcoholic Steatohepatitis (NASH): Quest for the Holy Grail

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Journal of Clinical and Translational Hepatology 2021年第1期9卷 40-50页

作者： Mithun Sharma Madhumita Premkumar Anand V Kulkarni Pramod Kumar d Nageshwar Reddy Nagaraja Padaki Rao department of Hepatology Asian Institute of GastroenterologyHyderabadIndia department of Hepatology PGIMERChandigarhIndia department of Gastroenterology Asian Institute of GastroenterologyHyderabadIndia

Nonalcoholic fatty liver disease (NAFLd) is a global epidemic that is likely to become the most common cause of chronic liver disease in the next decade, worldwide. Though numerous drugs have been evaluated in clinical trials, most of them have returned inconclusive results and shown poorly-tolerated adverse effects. None of the drugs have been approved by the Food and drug Administration for treating biopsy-proven non-alcoholic steatohepatitis (NASH). Vitamin E and pioglitazone have been extensively used in treatment of biopsy-proven nondiabetic NASH patients. Although some amelioration of inflammation has been seen, these drugs did not improve the fibrosis component of NASH. Therefore, dietary modification and weight reduction have remained the cornerstone of treatment of NASH;moreover, they have shown to improve histological activity as well as fibrosis. The search for an ideal drug or ‘Holy Grail’ within this landscape of possible agents continues, as weight reduction is achieved only in less than 10% of patients. In this current review, we summarize the drugs for NASH which are under investigation, and we provide a critical analysis of their up-to-date results and outcomes.

关键词： Fatty liver NAFLd NASH Obeticholic acid Saroglitazar

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Pleosporales

Fungal diversity 2012年第2期53卷 1-221页

作者： Ying Zhang Pedro W.Crous Conrad L.Schoch Kevin d.Hyde division of Microbiology School of Biological SciencesThe University of Hong KongPokfulam RoadHong KongSARPeople’s Republic of China CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD UtrechtThe Netherlands National Center for Biotechnology Information National Library of MedicineNational Institutes of Health45 Center DriveMSC 6510BethesdaMD 20892-6510USA School of Science Mae Fah Luang UniversityTasudMuangChiang Rai 57100Thailand Botany and Microbiology department College of ScienceKing Saud UniversityRiyadh 11442Saudi Arabia

One hundred and five generic types of Pleosporales are described and illustrated.A brief introduction and detailed history with short notes on morphology,molecular phylogeny as well as a general conclusion of each genus are *** those genera where the type or a representative specimen is unavailable,a brief note is *** 174 genera of Pleosporales are *** as well as Kriegeriella,Zeuctomorpha and Muroia are excluded from *** on the multigene phylogenetic analysis,the suborder Massarineae is emended to accommodate five families,***,Massarinaceae,Montagnulaceae,Morosphaeriaceae and Trematosphaeriaceae.

关键词： Generic type Massarineae Molecular phylogeny Morphology Pleosporales Taxonomy