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Prevalence of bacterial vaginosis and its risk factors in HIV/AIdS patients with abnormal vaginal discharge

Asian Pacific Journal of Tropical Medicine 2011年第2期4卷 156-158页

作者： Samuel Nwadioha d.niel egah Edmond Banwat Julie Egesie Ifeanyi Onwuezobe Medical Microbiology department College of Health SciencesBenue State UniversityMakurdi Medical Microbiology department Jos University Teaching HospitalJos Haematology department Jos University Teaching HospitalJos

Objective:To determine the prevalence of bacterial vaginosis in the HIV/AIdS patients of primary health care clinics in Jos Plateau state,***:Female genital swabs were collected from primary health care centers,Jos and analyzed by microscopy,culture,*** Jos University Teaching Hospital from december 2006 to december *** on epidemiologic indices were collected,using structured interviewer-administered ***: The incidence of bacterial vaginosis in the study was 28%(n=196/700).Among the HIV/AIdS group,the bacterial vaginosis incidence was 36%(n=126/350),while in the control(non-HIV patients) group,the rate was 20%(70/350) with a statistically significant difference at 95 percent confidence level(PdS and non-HIV(control) patients contributed 64%(n=126/196) and 36%(n=70/196),*** risks to bacterial vaginosis included vaginal douching with disinfectant/detergent constituted(60%),poor use of condom 40%,a median age of 26 years,and a median number of 3 sex partners per ***:There was a significant statistical difference in prevalence of bacterial vaginosis between the HIV/AIdS group and non-HIV(control) group of patients in the *** behaviors that promote the incidence of bacterial vaginosis should be especially paid attention.

关键词： Bacterial vaginosis HIV/AIdS Microscopy Culture Sensitivity

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Africa's 9th malaria day celebration in 2009 and its bearing on most vulnerable groups

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 294-297页

作者： Godwin T Jombo Emmanuel M Mbaawuaga Sebastin T Anongu danie Z egah Maximus N Enenebeaku Emmanuel E Okwori Chuks G Ejezie Ima Bassey Friday Odey department of Medical Microbiology and Parasitology College of Health SciencesBenue State University department of Biological Sciences Faculty of ScienceBenue State University department of Medical Microbiology College of Medical SciencesUniversity of JosNigeria department of Medical Microbiology and Parasitology College of Medical SciencesUniversity of Calarar department of Histopathology College of Medical SciencesUniversity of Calarar department of Paediatrics College of Medical SciencesUniversity of Calarar

Objective:To investigate the incidence of malaria and anaemia among children after the ninth malaria day ***:Children attending primary healthcare centres in Makurdi for routine immunization purposes were recruited between September and November 2008 into the *** and thin blood films from arterial blood were stained with Giemsa’s stain and examined microscopically;packed cell volume(PCV) was measured using haematocrit machine and body temperatures with the aid of paediatric thermometers;other anthropometric measurements were also *** relevant information on the children and their parents were obtained with the aid of a structured *** obtained was analysed using Epi Info statistical s of tware,P values≤0.05 were considered ***:The incidence of Plasmodium falciparum parasitaemia was 32.3%among the 502 children;85.9%(n=139) of children with malaria parasites were anaemic and 88.9%(8/9) of the children with fever had *** were commoneT in children aged one year and above(Pde treated bed nets(TTNs) was 24.7%(n=124) while 27.9%(n=140) used untreated bed *** was no significant difference in malaria incidence among those who used ITNs, untreated nets and other unconventional control methods(P>0.05).Educational level of mothers had no significant impact on the incidence of malaria among the children(P>0.05),while occupation had(Pd anaemia are still major health problems in Makurdi city as in several other parts of sub-Saharan *** of ITNs and massive health education at the grass root should be stepped up,and possibly supply of facilities for rapid malaria diagnosis to the community should be considered.

关键词： Malaria Anaemia Children Incidence

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Prevalence, Clinical Features and Outcome of Neonatal Malaria in Two Major Hospitals in Jos, North-Central Nigeria

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Advances in Infectious diseases 2017年第3期7卷 55-69页

作者： Udochukwu M. diala Kenneth I. Onyedibe Akinyemi O. d. Ofakunrin Olubunmi O. diala Bose Toma d.niel egah Stephen Oguche department of Paediatrics University of Jos Jos Plateau State Nigeria department of Medical Microbiology University of Jos Plateau State Nigeria department of Family Medicine Jos University Teaching Hospital Jos Plateau State Nigeria

Malaria was thought to be rare in neonates. However, recent studies report increasing prevalence in neonates. Clinical features of neonatal malaria have also not been adequately reported. This study was undertaken to assess the prevalence, clinical features and outcome of malaria in neonates admitted into two tertiary hospitals in Jos, Plateau State. All consecutive neonates aged 0 - 28 days admitted into the neonatal units of Jos University Teaching Hospital and Bingham University Teaching Hospital, Jos were recruited into the study. Giemsa stained blood films of the neonates were examined by trained microscopists. Neonates with malaria had presenting clinical features recorded and treated with amodiaquine (1st line) and quinine (2nd line). Clinical features and parasitaemia were monitored for 14 days for outcome. Of the 301 neonates enrolled, 16 had malaria parasitaemia giving a prevalence of 5.3%. Congenital malaria accounted for 87.5% of cases of neonatal malaria. Plasmodium falciparum mono-infection was responsible for all the cases of malaria. ITN use in pregnancy offered some protection against neonatal malaria (CI=0.2 - 0.7). The median parasite density was 255 (72, 385) parasites/μl. Fever was significantly present in 10 (66.7%) of the cases (p=0.03). Fifteen of the 16 neonates had clinical and parasitological cure on treatment with amodiaquine. One treatment failure had cure after retreatment with quinine. There was no mortality in all 16 neonates treated for malaria. Malaria is not rare in neonates on admission in Jos. Fever is the commonest clinical feature of neonatal malaria. Amodiaquine provided effective treatment of malaria in neonates in Jos.

关键词： Neonatal Malaria Prevalence Amodiaquine Bed Nets

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Low Prevalence of Carbapenem Resistance in Clinical Isolates of Extended Spectrum Beta Lactamase (ESBL) Producing <i>Escherichia coli</i>in North Central, Nigeria

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Advances in Infectious diseases 2018年第3期8卷 109-120页

作者： Kenneth I. Onyedibe Emmanuel O. Shobowale Mark O. Okolo Michael O. Iroezindu Tolulope O. Afolaranmi Francisca O. Nwaokorie Solomon O. Opajobi Samson E. Isa d.niel Z. egah department of Medical Microbiology University of Jos Jos Nigeria department of Medical Microbiology Babcock University Ilishan-Remo Nigeria department of Medicine University of Nigeria Nsukka Nigeria department of Epidemiology & Community Health University of Jos Jos Nigeria division of Molecular Biology Nigerian Institute of Medical Research Lagos Nigeria department of Medicine University of Jos Jos Nigeria

Extended Spectrum Beta Lactamase (ESBL) producing Escherichia coli is a global cause of life threatening infections. We determined the presence of ESBL and carbapenemase production in clinical isolates of E. coli and their antibiotic susceptibility. Clinical isolates of community and hospital acquired E. coli from 220 patients seen at a tertiary hospital were evaluated. Antibiotic susceptibility testing was by the modified Kirby-Bauer protocol while ESBL production was determined by the double disk Synergy Test (ddST). Carbapenem resistance was confirmed by the Modified Hodge Test. Of the 220 isolates, 122 (55.5%) were from females;41 (18.6%) were ESBL positive. About 90% of the ESBL producing isolates were resistant to nine of the 15 antimicrobial agents tested. However, only one (2.4%) of the 41 ESBL producing isolates exhibited carbapenem resistance. The ESBL negative isolates were susceptible to Meropenem (100%), Cefepime (97.8%), Ceftriaxone (96.6%) and Cefotaxime (96.6%). All the ESBL producing isolates harbored detectable plasmids with sizes ranging from 2322 to 23,130 base pairs. Our findings show that although multidrug resistant ESBL producing E. coli are prevalent in both the hospital and the community in this environment, carbapenem resistance is still low. We recommend that institutions develop guidelines for the early phenotypic detection of ESBLs and carbapenem resistance.

关键词： E. coli ESBL Plasmids Carbapenem Resistance Nigeria

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