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journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j Rivenbark Timothy d Phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and aminomethylphosphonic acid(AMPA)in contaminated water,soil,sediment and plants is a cause for concern due to potential threats to the ecosystem and human health.A major route of exposure is through contact with contaminated soil and consumption of crops containing GLP and AMPA ***,clay-based sorption strategies for mixtures of GLP and AMPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AMPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(CM)and acid processed montmorillonite(APM)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent manner without detectable *** treated with 0.5%and 1%APM inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that montmorillonite clays could be added as soil supplements to reduce hazardous mixtures of GLP and AMPA in soils and plants.

关键词： Glyphosate AMPA Adsorption Soil remediation Plant Hydroponic system

Generalized polynomial chaos expansion by reanalysis using static condensation based on substructuring

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Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 819-836页

作者： d.LEE S.CHANG j.LEE department of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea department of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method for forward uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and dependent random *** method consists of a generalized polynomial chaos expansion(GPCE)for statistical moment and reliability analyses associated with the stochastic output and a static reanalysis method to generate the input-output data *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary due to random *** allows for avoiding repeated computations of invariant substructures while generating the input-output data *** substructuring with static condensation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method can achieve significant computational saving,thus mitigating the curse of dimensionality to some degree for UQ under high-dimensional *** numerical results obtained from a simple structure indicate that the proposed method for UQ produces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also demonstrate the efficiency and scalability of the proposed method by executing UQ for a large-scale wing-box structure under ten-dimensional(all-dependent)random inputs.

关键词： forward uncertainty quantification(UQ) generalized polynomial chaos expansion(GPCE) static reanalysis method static condensation substructuring

基于影像质量的可检测CT辐射剂量最优化系统第二部分:过程控制系统

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国际医学放射学杂志 2013年第6期 585-585页

作者： d.B.Larson R.j.Malarik S.M.Hall d.j.podberesky 刘莹莹 department of Radiology Stanford University School of Medicine 300 Pasteur Dr Stanford CA 94305-5105

摘要目的评价CT在胸部、腹部和骨盆检查中,辐射剂量优化和过程控制系统对于影像噪声和体型特异性剂量估计(SSdE)一致性的效果。材料与方法这个质量改进项目不

关键词：辐射剂量噪声噪音过程控制系统 CT

儿童和青少年CT小肠成像滤过反投影重建技术和降低自适应迭代剂量3d重建技术的诊断性能和辐射剂量比较

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国际医学放射学杂志 2015年第5期 475-475页

作者： d.B.Wallihan d.j.podberesky j.Sullivan L.A.denson B.Zhang S.R.Salisbury 罗厚丽 department of Radiology Cincinnati Children ’s Hospital Medical Center

摘要目的探讨儿童和青少年CT小肠成像滤过反投影重建技术(FBP)和降低自适应迭代剂量3d重建技术(AIdR的诊断性能和辐射剂量。材料与方法本研究经伦理委员会批准,符合HIPAA并免除了知情同意。本研究收集的病例在45 d内均取得病理结果,CT... 详细信息

摘要目的探讨儿童和青少年CT小肠成像滤过反投影重建技术(FBP)和降低自适应迭代剂量3d重建技术(AIdR的诊断性能和辐射剂量。材料与方法本研究经伦理委员会批准,符合HIPAA并免除了知情同意。本研究收集的病例在45 d内均取得病理结果,CT小肠成像检查包括:2008年1月—2009年6月期间行FBP技术检查、2012年8月—201年4月期间行AIdR 3d技术检查。2名研究者独立研究活动

关键词：重建技术辐射剂量诊断性能小肠自适应迭代反投影儿童 CT 滤过

Insm1:orchestrating cellular mimicry in the thymus medulla

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Cellular & Molecular Immunology 2024年第4期21卷 414-416页

作者： K.d.james j.E.Cowan UCL Institute of Immunity and Transplantation The Pears BuildingRowland Hill StreetLondonNW32PPUK

The thymus is the primary production site for a functional and self-tolerant T-cell *** establishment of immune tolerance is mediated by the generation and presentation of tissue-restricted self-antigens(TRAs)by medullary thymic epithelial cells(mTECs),which screen T-cell receptors for self-reactivity to eliminate autoreactive T *** studies have extended our understanding of mTEC heterogeneity by examining the mechanisms by which mTECs mimic the peripheral self[1].

关键词： medullary eliminate restricted

Mucopolysaccharidosis typeⅢB:a current review and exploration of the AAV therapy landscape

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Neural Regeneration Research 2024年第2期19卷 355-359页

作者： Courtney j.Rouse Victoria N.jensen Coy d.Heldermon Lacerta Therapeutics AlachuaFLUSA University of Florida College of Medicine GainesvilleFLUSA

Mucopolysaccharidoses typeⅢB is a rare genetic disorder caused by mutations in the gene that encodes for *** results in the aggregation of heparan sulfate polysaccharides within cell lysosomes that leads to progressive and severe debilitating neurological *** treatment options are expensive,limited,and presently there are no approved cures for mucopolysaccharidoses typeⅢ***-associated virus gene therapy has significantly advanced the field forward,allowing researchers to successfully design,enhance,and improve potential *** group recently published an effective treatment using a codon-optimized triple mutant adeno-associated virus 8 vector that restores N-acetyl-alpha-glucosaminidase levels,auditory function,and lifespan in the murine model for mucopolysaccharidoses typeⅢB to that seen in healthy ***,we review the current state of the field in relation to the capsid landscape,adeno-associated virus gene therapy and its successes and challenges in the clinic,and how novel adenoassociated virus capsid designs have evolved research in the mucopolysaccharidoses typeⅢB field.

关键词： adeno-associated virus central nervous system gene therapy heparan sulfate immune response mucopolysaccharidoses type IIIB N-acetyl-alpha-glucosaminidase newborn screening

同行反馈、学习和改进:回应美国国家医学院关于诊断错误的报告

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国际医学放射学杂志 2017年第3期 350-350页

作者： d.B.Larson L.F.donnelly d.j.podberesky A.C.Merrow R.E.Sharpe j.B.Kruskal 程亚丽张艳秋 department of Radiology Stanford University School of Medicine

摘要 2015年9月美国国家医学院发表了一篇题为"改善卫生保健诊断"的报告,它建议"卫生保健机构应该采用非惩罚性的文化政策和措施,对医生的诊断效能进行公开讨论和反馈"。有些不可思议的是,报告将高度专业性技能例如医疗诊断聚焦在组织... 详细信息

摘要 2015年9月美国国家医学院发表了一篇题为"改善卫生保健诊断"的报告,它建议"卫生保健机构应该采用非惩罚性的文化政策和措施,对医生的诊断效能进行公开讨论和反馈"。有些不可思议的是,报告将高度专业性技能例如医疗诊断聚焦在组织文化上。然而对人们专业领域里犯的错误以及个人和组织绩效方面的最新研究已使有关认识更加清晰。目前放射科医生业务能力提升的主导模式是基于同行评议的评分,这种模式反映了传统的质量保证方法,其起源于20世纪中期的制造行业。现已建立了基于同行评议的评分系统,

关键词：同行医学院医学院校美国美利坚合众国北美洲

Generalized time-dependent generator coordinate method for induced fission dynamics

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Frontiers of physics 2024年第4期19卷 1-12页

作者： B.Li d.Vretenar T.Nikšić j.Zhao P.W.Zhao j.Meng State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Physics department Faculty of ScienceUniversity of Zagreb10000 ZagrebCroatia Center for Circuits and Systems Peng Cheng LaboratoryShenzhen 518055China

The generalized time-dependent generator coordinate method(Td-GCM)is extended to include pairing *** correlated GCM nuclear wave function is expressed in terms of time-dependent generator states and weight *** particle–hole channel of the effective interaction is determined by a Hamiltonian derived from an energy density functional,while pairing is treated dynamically in the standard BCS approximation with time-dependent pairing tensor and single-particle occupation *** the inclusion of pairing correlations,various time-dependent phenomena in open-shell nuclei can be described more *** model is applied to the description of saddle-to-scission dynamics of induced *** generalized Td-GCM charge yields and total kinetic energy distribution for the fission of 240Pu,are compared to those obtained using the standard time-dependent density functional theory(Td-dFT)approach,and with available data.

关键词： nuclear density functional theory generator coordinate method fission dynamics

Malargüe Site Remediation: A Successful Solution for Uranium Mill Tailings

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原子能科学技术 2024年

作者： BARARI E díAZ j G GIOMIA KEMPF R A National Atomic Energy Commission Av.Del Libertador 8250 Ciudad Autónoma de Buenos AiresC1429BNP Argentina

Comisión Nacional de Energía Atómica(CNEA) has the responsibility for restoring uranium mining facilities once the operations have finished. CNEA, within its Environmental Program and in compliance with its legal responsibilities, decides to implement a restoration project for all sites related to the mining and processing of uranium ores. The Malargüe Site is located within the Province of Mendoza in the city of Malargüe. It is the first site to successfully complete its remediation. The activities consist of relocation of tailings to an engineering repository. The tailings management(encapsulation) and rehabilitation of the area was finished in june 2017. The remediation alternative for the ore tailings was selected after conducting comparative studies and submitted the project to the society for consideration. The objective of the encapsulation of the mineral tails is to isolate them from the environment, also proceeding with the decontamination and rehabilitation of the area(landscaping,post-closure monitoring and 20 years monitoring period). Encapsulation consisted of the construction of a containment cell for the mine tailings, to isolate them and prevent pollutants from entering the environment through the transfer routes. To clean the impacted areas, the soil was removed, it was incorporated into the encapsulation, and the filling was carried out with natural soils from the *** prevents radon transfer to the environment, as 222Ra is an alpha emitter with a half-life of four days, which produces its own radioactive progeny. Radon progeny are solids, and when a 222Ra nucleus emits an alpha particle into the air, the resulting 218Po nucleus, momentarily electrically charged, adheres to any dust particle. Remediation prevents the discharge into the air containing radon and also containing dust particles charged with intensely radioactive radon progeny. The tasks mentioned make it possible to decrease radon emanation, reduce radiological risks to the

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Greatly enhanced corrosion/wear resistances of epoxy coating for Mg alloy through a synergistic effect between functionalized graphene and insulated blocking layer

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journal of Magnesium and Alloys 2024年第1期12卷 332-344页

作者： Z.Y.Xue X.j.Li j.H.Chu M.M.Li d.N.Zou L.B.Tong School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an 710055China State Key Laboratory of Advanced design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

The poor corrosion and wear resistances of Mg alloys seriously limit their potential applications in various *** conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient *** the current study,we design a double-layer epoxy composite coating on Mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly *** outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)and the inner layer is Ce-based conversion(Ce)*** FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects and improve the barrier *** Ce film connects the outer layer with the substrate,showing the transition *** corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare Mg alloy,and the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)and the obstruction of galvanic coupling *** synergistic effect derived from the FG sheet and blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of Mg alloys.

关键词： Mg alloy Functionalized graphene Epoxy coating Corrosion/wear resistance Blocking layer