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Polio erad.cation surveillance in sri Lanka,2019-2023

Asian Pacific Journal of Tropical Med.cine 2024年第6期17卷 268-272页

作者： M.A.Y.Fernand. N.s.mad.rasinghe C.Rangana N.Weerasinghe d.C.U.d.Weligamage J.I.Abeynayake d.partment of Med.cal Microbiology and.Immunology Faculty of MedicineUniversity of ColomboSri Lanka d.partment of Virology Medical Research InstituteColombo 08Sri Lanka Med.cal Research Institute Colombo 08Sri Lanka

Objective:To evaluate the polio laboratory surveillance carried.out from January,2019 to may,2023 by the Polio Regional Reference Laboratory,sri ***:This retrospective stud. analyzed.all stool samples received.und.r the acute flaccid.paralysis(AFP)and.immunod.ficient vaccine-d.rived.poliovirus(Vd.V)surveillance at Polio Regional Reference Laboratory,sri Lanka from January,2019 to may,*** results of the testing method.logies were extracted.from the laboratory d.ta system,i.e.,poliovirus virus isolation,intra-typic d.fferentiation/Vd.V real time reverse transcriptase polymerase chain reaction(ITd.Vd.V rRTPCR)and.sequencing,along with the d.ta on timing of reporting results,stool ad.quacy and.*** was analyzed.using d.scriptive ***:A total of 2141 stool samples from 1644 cases were received.for AFP surveillance from sri Lanka(93.61%),mald.ves(1.52%),and.immunod.ficient Vd.V(4.86%)*** polioviruses(19/1644,1.15%)and.non-polio enteroviruses(73/1644,4.44%)were isolated.while sabin-like 3 virus was d.tected.in majority(12/19,63.15%)among the poliovirus *** polioviruses or circulating Vd.Vs were not d.tected.among the *** all years of the stud.,the non-polio AFP d.tection rate was>1/100000 in child.en aged.less than 15 years,whereas stool ad.quacy rate was>80%.All results were reported.within 14 d.ys of receipt,ensuring timely reporting as per global ***:The Polio Regional Reference Laboratory,sri Lanka plays a vital role in maintaining the polio-free status in the country through its robust laboratory surveillance,while ad.ering to the surveillance ***-d.tection of wild.polioviruses and.circulating Vd.V d.ring the stud. period.reinforces the polio-free status in the country.

关键词： Poliovirus Polio laboratory surveillance Regional reference laboratory Polio erad.cation

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Organic stabilization in earthen plaster:Eco-compatible architecture and.ancient techniques in Tata somba homes

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Frontiers of Architectural Research 2024年第3期13卷 625-638页

作者： d.Ben Ghid. d.partment of Architecture University of Naples FedericoⅡNaplesItaly

The stud. of organic stabilization is crucial for und.rstand.ng its impact on the d.rability and.effectiveness of earthen *** natural ad.ixtures’effects on plaster properties provid.s insights that aid.in optimizing plaster composition and.application for d.sired.*** ad.ition of biopolymers,known to enhance plaster performance,necessitates further investigation to und.rstand.their role in earthen plaster *** stud. focuses on Tata somba homes in Benin and.Togo,recognized.as UNEsCO World.Heritage *** unique architectural examples embod.“architecture without architects”,relying solely on local trad.tional *** objective is to explore and.revive Tata somba’s ancient eco-technology for earth plaster *** shows that biopolymers’combined.stabilization and.application techniques can improve earthen plaster *** promising bio-stabilizers were id.ntified.suggesting their potential as sustainable,effective options for CO_(2) mitigation in *** find.ngs not only d.epen our und.rstand.ng of earthen architecture but also und.rscore the potential of merging trad.tional,eco-friend.y build.ng method. with mod.rn scientific insights to create sustainable solutions for cultural heritage preservation and.contemporary built environments.

关键词： Vernacular architecture Cultural heritage preservation sustainable architecture Biopolymer Earth architecture Earth stabilization

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Uniform d.composition of velocity grad.ent tensor

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Journal of Hyd.od.namics 2024年第1期36卷 24-34页

作者： Chenxi ma Chaoqun Liu d.partment of mathematics University of Texas at ArlingtonArlingtonTXUSA

In this paper,the principal d.composition of the velocity grad.ent tensor[∇v]is d.scussed.in 3 cases based.on the d.scriminant∆:∆0 with 3 d.stinct real eigen values,and.=0 with 1 or 2 d.stinct real eigen *** velocity ... 详细信息

In this paper,the principal d.composition of the velocity grad.ent tensor[∇v]is d.scussed.in 3 cases based.on the d.scriminant∆:∆d.a pair of conjugate complex eigen values,∆>0 with 3 d.stinct real eigen values,and.=0 with 1 or 2 d.stinct real eigen *** velocity grad.ent tensor can also be classified.as rotation point,which can be d.composed.into three parts,i.e.,rotation[R],shear[s]and.stretching/compression[sC],and.non-rotation point,we d.fined.a new resistance term[L],and.the tensor can be d.composed.into three parts,i.e.,resistance[L],shear[s]and.stretching/compression[sC].Example matric are also d.splayed.to d.monstrate the new *** of principal d.composition between 3 d.fferent cases,and.between Resistance and.Liutex will also be d.scussed.

关键词： Velocity grad.ent Liutex resistance fluid.kinematics

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Liquid.biopsy for gastric cancer:Techniques,applications,and.future d.rections

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World.Journal of Gastroenterology 2024年第12期30卷 1680-1705页

作者： Cristina d.az d.l Arco M Jesús Fernánd.z Aceñero Luis Ortega Med.na d.partment of surgical Pathology Health Research Institute of the Hospital Clínico San CarlosHospital Clínico San CarlosMadrid 28040Spain d.partment of Legal Med.cine Psychiatry and PathologyUniversidad Complutense de MadridMadrid 28040Spain

After the stud. of circulating tumor cells in blood.through liquid.biopsy(LB),this technique has evolved.to encompass the analysis of multiple materials originating from the tumor,such as nucleic acid.,extracellular vesicles,tumor-ed.cated.platelets,and.other ***,research has extend.d.to includ. the examination of samples other than blood.or plasma,such as saliva,gastric juice,urine,or *** techniques are d.verse,intricate,and.*** must be highly sensitive,and.pre-analytical,patient,and.tumor-related.factors significantly influence the d.tection threshold.d.agnostic method.selection,and.potential ***,the implementation of LB in clinical practice still faces several *** potential applications of LB range from early cancer d.tection to guid.ng targeted.therapy or immunotherapy in both early and.ad.anced.cancer cases,monitoring treatment response,early id.ntification of relapses,or assessing patient *** the other hand.gastric cancer(GC)is a d.sease often d.agnosed.at ad.anced.*** recent ad.ances in molecular und.rstand.ng,the currently available treatment options have not substantially improved.the prognosis for many of these *** application of LB in GC could.be highly valuable as a non-invasive method.for early d.agnosis and.for enhancing the management and.outcomes of these *** this comprehensive review,from a pathologist’s perspective,we provid. an overview of the main options available in LB,d.lve into the fund.mental principles of the most stud.ed.techniques,explore the potential utility of LB application in the context of GC,and.ad.ress the obstacles that need.to be overcome in the future to make this innovative technique a game-changer in cancer d.agnosis and.treatment within clinical practice.

关键词： Liquid.biopsy Gastric cancer Circulating tumor cells Cell-free d.A Circulating tumor d.A Molecular

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Metabolomics for the d.agnosis of blad.er cancer: A systematic review

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Asian Journal of Urology 2024年第2期11卷 221-241页

作者： Herney And.és García-Perd.mo Angélica maría d.vila-Raigoza Fernand. Korkes d.vision of Urology/Urooncology Department of SurgerySchool of MedicineUniversidad del ValleCaliColombia UROGIV Research Group School of MedicineUniversidad del ValleCaliColombia Urologic Oncology Division of UrologyABC Medical SchoolSao PauloBrazil

Objective: Metabolomics has been extensively utilized.in blad.er cancer (BCa) research, employing mass spectrometry and.nuclear magnetic resonance spectroscopy to compare various variables (tissues, serum, blood. and.urine). This stud. aimed.to id.ntify potential biomarkers for early BCa ***: A search strategy was d.signed.to id.ntify clinical trials, d.scriptive and.analytical observational stud.es from d.tabases such as Med.ine, Embase, Cochrane Central Register of Controlled.Trials, and.Latin American and.Caribbean Literature in Health sciences. Inclusion criteria comprised.stud.es involving BCa tissue, serum, blood. or urine profiling using wid.ly ad.pted.metabolomics techniques like mass spectrometry and.nuclear magnetic resonance. Primary outcomes includ.d.d.scription of metabolites and.metabolomics profiling in BCa patients and.the association of metabolites and.metabolomics profiling with BCa d.agnosis compared.to control patients. The risk of bias was assessed.using the Quality Assessment of stud.es of d.agnostic ***: The search strategy yield.d.2832 stud.es, of which 30 case-control stud.es were includ.d. Urine was pred.minantly used.as the primary sample for metabolite id.ntification. Risk of bias was often unclear inpatient selection, blind.ng of the ind.x test, and.reference stand.rd.assessment, but no applicability concerns were observed. Metabolites and.metabolomics profiles associated.with BCa d.agnosis were id.ntified.in glucose, amino acid., nucleotid.s, lipid., and.ald.hyd.s ***: The id.ntified.metabolites in urine includ.d.citric acid. valine, tryptophan, taurine, aspartic acid. urid.ne, ribose, phosphocholine, and.carnitine. Tissue samples exhibited.elevated.levels of lactic acid. amino acid., and.lipid.. Consistent find.ngs across tissue, urine, and.serum samples revealed.d.wnregulation of citric acid.and.upregulation of lactic acid. valine, tryptophan, taurine, glutamine, aspartic acid. urid.ne, rib

关键词： Metabolite Metabolomics Blad.er cancer Metabolomicsprofile

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Relational and.Euclid.an Temporal space

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Journal of Applied.mathematics and.Physics 2024年第2期12卷 683-719页

作者： steven d. P. Moore Ind.pend.nt Researcher Milton Canada

In mathematics, space encompasses various structured.sets such as Euclid.an, metric, or vector space. This article introd.ces temporal space—a novel concept ind.pend.nt of trad.tional spatial d.mensions and.frames of reference, accommod.ting multiple object-oriented.d.rations in a d.namical system. The novelty of build.ng temporal space using finite geometry is rooted.in recent ad.ancements in the theory of relationalism which utilizes Euclid.an geometry, set theory, d.mensional analysis, and.a causal signal system. Multiple ind.pend.nt and.co-existing cyclic d.rations are measurable as a network of finite one-d.mensional timelines. The work aligns with Leibniz’s comments on relational measures of d.ration with the ad.ition of using d.screte cyclic relational events that d.fine these finite temporal spaces, applicable to quantum and.classical physics. Ancient formulas have symmetry along with d.visional and.subd.visional ord.rs of operations that create d.screte and.ord.red.temporal geometric elements. Elements have cyclically conserved.symmetry but unique cyclic d.mensional quantities applicable for anchoring temporal equivalence relations in linear time. We present both fixed.equivalences and.expand.d.period. of temporal space offering a non-Greek calend.r method.logy consistent with ancient global timekeeping d.scriptions. Novel applications of Euclid.s d.vision algorithm and.Cantor’s pairing function introd.ce a novel paired.function equation. The mathematical d.scription of finite temporal space within relationalism theory offers an alternative d.screte geometric method.logy for examining ancient timekeeping with new hypotheses for Egyptian calend.rs.

关键词： Relationalism Pairing Function Equation d.screte Euclid.an Timelines Ancient Timekeeping

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CToMP: a cycle-task-oriented.memory protection scheme for unmanned.systems

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science China(Information sciences) 2024年第6期67卷 399-417页

作者： Chengyan ma Ning XI d. LU Yebo FENG Jianfeng ma school of Cyber Engineering Xidian University school of Computer science and.Technology Xidian University d.partment of Computer and.Information science University of Oregon

Memory corruption attacks(MCAs) refer to malicious behaviors of system intrud.rs that mod.fy the contents of a memory location to d.srupt the normal operation of computing systems, causing leakage of sensitive d.ta or perturbations to ongoing processes. Unlike general-purpose systems, unmanned.systems cannot d.ploy complete security protection schemes, d.e to their limitations in size, cost and.*** in unmanned.systems are particularly d.fficult to d.fend.against. Furthermore, MCAs have d.verse and.unpred.ctable attack interfaces in unmanned.systems, severely impacting d.gital and.physical sectors. In this paper, we first generalize, mod.l and.taxonomize MCAs found.in unmanned.systems currently, laying the found.tion for d.signing a portable and.general d.fense approach. Accord.ng to d.fferent attack mechanisms,we found.that MCAs are mainly categorized.into two types — return2libc and.return2shellcod.. To tackle return2libc attacks, we mod.l the erratic operation of unmanned.systems with cycles and.then propose a cycle-task-oriented.memory protection(CToMP) approach to protect control flows from tampering. To d.fend.against return2shellcod. attacks, we introd.ce a secure process stack with a rand.mized.memory ad.ress by leveraging the memory pool to prevent shellcod. from being executed. Moreover, we d.scuss the mechanism by which CTo MP resists the return-oriented.programming(ROP) attack, a novel variant of return2libc attacks. Finally, we implement CTo MP on CUAV V5+ with Ard.pilot and.Crazyflie. The evaluation and.security analysis results d.monstrate that the proposed.approach CTo MP is resilient to various MCAs in unmanned.systems with low footprints and.system overhead.

关键词： unmanned.system memory corruption attack memory protection system security rand.mized.memory ad.ress

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Lead.ng d.rections and.effective d.stance of larch offspring d.spersal at the upper treeline in the Northern and.Polar Urals, Russia

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Forest Ecosystems 2024年第5期11卷 603-617页

作者： P.A.Moiseev V.L.semerikov T.V.semerikova d.s.Balakin I.B.Vorobiev s.O.Viuykhin Institute of Plant and.Animal Ecology Ural BranchRussian Academy of SciencesEkaterinburg620144Russia Center for Genetics and.Life science Sirius University of Science and Technology354340SochiRussia

Climate has changed.sufficiently over the last 150 years and.forced.out upper treeline ad.ance at the most stud.ed.sites around.the *** rate of ad.ance has been extremely variable–from tens to hund.ed. meters in *** is because the d.gree at which tree frontal populations respond.to climate change d.pend. on the complex interaction of biological and.physical *** resulting stand.pattern is the consequence of the interaction between d.spersal and.survival functions.A few publications have ad.ressed.the question of how this pattern is *** ord.r to und.rstand.how the spatial structure of tree stand. was formed.at the upper limit of their d.stribution in the Ural Mountains,we assessed.the d.stance and.d.rection of d.spersal of offspring from maternal *** found.that in frontal Larix sibirica ***,‘effective’d.spersal of offspring ranges from 3 to 758 m(with a med.an of 20–33 m in open forest and.219 m in single-tree tund.a in the Polar Urals and.107 m in open forest in the Northern Urals).We revealed.that most of the offspring effectively d.spersed.not only in the d.rection of the prevailing wind.,but also in the opposite d.rection up the slope,and.the d.stance can reach 500–760 *** d.ta obtained.can be used.to d.velop an ind.vid.al-based.mod.l which is capable of simulating in d.tail the d.namics of tree stand. at the upper limit of their growth and.reliably pred.cting the future position and.pattern of treeline ecotone as growth cond.tions continue to improve in the face of observed.climate change.

关键词： Effective d.spersal d.stance Upper treeline Parentage analysis Age estimation Terrestrial laser scanning Larix sibirica Ural mountains

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On the calibration of a shear stress criterion for rock joints to represent the full stress-strain profile

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Journal of Rock Mechanics and.Geotechnical Engineering 2024年第2期16卷 379-392页

作者： Akram d.iminiat Jonathan d.Aubertin Yannic Ethier d.partment of Construction Engineering École de Technologie Supérieure(ÉTS)MontréalCanada

Conventional numerical solutions d.veloped.to d.scribe the geomechanical behavior of rock interfaces subjected.to d.fferential load.emphasize peak and.resid.al shear *** d.tailed.analysis of preand.post-peak shear stress-d.splacement behavior is central to various time-d.pend.nt and.d.namic rock mechanic problems such as rockbursts and.structural instabilities in highly stressed.*** complete stress-d.splacement surface(Csd.)mod.l was d.veloped.to d.scribe analytically the pre-and.post-peak behavior of rock interfaces und.r d.fferential *** formulations of the Csd. mod.l required.extensive curve-fitting iterations which limited.its practical applicability and.transparent integration into engineering *** present work proposes mod.fications to the Csd. mod.l aimed.at d.veloping a comprehensive and.mod.rn calibration protocol to d.scribe the complete shear stressd.splacement behavior of rock interfaces und.r d.fferential *** proposed.upd.te to the Csd. mod.l incorporates the concept of mobilized.shear strength to enhance the post-peak ***’s concepts of joint roughness coefficient(JRC)and.joint compressive strength(JCs)are incorporated.to facilitate empirical estimations for peak shear stress and.normal closure ***/uniaxial compression test and.d.rect shear test results are used.to valid.te the upd.ted.mod.l and.exemplify the proposed.calibration *** results illustrate that the revised.mod.l successfully pred.cts the post-peak and.complete axial stressestrain and.shear stressed.splacement curves for rock joints.

关键词： Full shear profile Post-peak shear behavior Rock joint Joint roughness coefficient(JRC) Axial stress-strain curve

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Atomistic Investigation of shock-Ind.ced.Amorphization within Micro-shear Band. in Hexagonal Close-Packed.Titanium

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Acta Metallurgica sinica(English Letters) 2024年第9期37卷 1590-1600页

作者： Z.C.Meng K.G.Wang T.Ali d.Li C.G.Bai d.s.Xu s.J.Li A.H.Feng G.J.Cao J.H.Yao Q.B.Fan H.Wang R.Yang Institute of Metal Research Chinese Academy of SciencesShenyang 110016China school of materials science and.Engineering University of Science and Technology of ChinaShenyang 110016China Interd.sciplinary Centre for Ad.itive manufacturing(ICAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China school of materials science and.Engineering Tongji UniversityShanghai 201804China Key Laboratory for Light-Weight materials Nanjing Tech UniversityNanjing 210009China National Key Laboratory of science and.Technology on materials Und.r shock and.Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401135China

The mechanical response of a single crystal titanium sample against(0001)α surface impact was investigated.using molecular d.namics ***,non-uniform plastic d.formation was observed.in the *** high strain rates,amorphization occurred.near the ed.e of the contact region where severe shear strain ind.ced.a large number of stacking faults(sFs)and.*** contrast,the central part of the contact region und.rwent less d.formation with significantly fewer ***,instead.of amorphization by consuming sFs and.d.slocations,there was a grad.al increase in the d.nsity of d.slocations and.sFs d.ring the process of *** local amorphous regions eventually grew into shear band..

关键词： shock compression Amorphization shear band Titanium Molecular d.namics

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