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熔融纺丝制备沥青碳纤维

新型炭材料 1990年第3期6卷 32-40页

作者： d.d.edie M.G.dunham(U.S.A) 李庚平杨波

尽管采用熔融纺丝可以制备沥青基炭纤维,但由于中间相沥青具有特殊的流动性,使其生产加工十分困难。中间相沥青象许多流体一样,均为非牛顿流体,但它的粘度对温度的敏感性比其它纺丝原料强的多。本文引用了力和能量平衡来论证工艺条件的... 详细信息

尽管采用熔融纺丝可以制备沥青基炭纤维,但由于中间相沥青具有特殊的流动性,使其生产加工十分困难。中间相沥青象许多流体一样,均为非牛顿流体,但它的粘度对温度的敏感性比其它纺丝原料强的多。本文引用了力和能量平衡来论证工艺条件的变化和原料性质对中间相沥青的可纺性的影响,结果表明:在熔融纺丝过程中,中间相沥青的粘度对温度的强烈依赖性使纤维丝产生应力,其大小趋近于单丝的极限抗拉强度。因此,在沥青基炭纤维的制备过程中,温度和传热速率的控制是十分重要的。

关键词：沥青碳纤维熔融纺丝

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熔融纺制的沥青基炭纤维

炭素技术 1990年第4期9卷 17-22页

作者： d.d.edie M.G.dunham 袁经琏

虽然沥青基炭纤维可以熔融纺制,但中间相沥青的流动性使得它极难处置。同许多液体一样,中间相沥青也可以是非牛顿型的。但其粘度对温度的敏感性要比大多数熔融纺丝物料的感性高得多。在本研究中,应用能量平衡和力平衡来论证工艺参数和... 详细信息

虽然沥青基炭纤维可以熔融纺制,但中间相沥青的流动性使得它极难处置。同许多液体一样,中间相沥青也可以是非牛顿型的。但其粘度对温度的敏感性要比大多数熔融纺丝物料的感性高得多。在本研究中,应用能量平衡和力平衡来论证工艺参数和原料性质对中间相可纺性的影响。研究结果表明:在熔融纺丝期间,温度与中间相粘度的相关性会产生丝的应力,这种应力接近丝的抗拉强度极限。因此,在沥青基炭纤维形成过程中,控制温度和传热速率是极为关键的。

关键词：沥青基炭纤维熔融纺丝

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熔融纺制的沥青基炭纤维(续)

炭素技术 1990年第5期9卷 23-25页

作者： d.d.edie M.G.dunham 袁经链

4.3.4 骤冷条件由于在大多数传统的纺丝工艺中,为提高固化速度和避免射流分散,人们都采用骤冷空气,沿与挤压中的丝垂直的方向吹送的方法,所以,在中间相沥青纺丝中,骤冷空气的作用就多少有点让人感到意外。

关键词：炭纤维沥青基烷融纺丝

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熔融纺制非园形碳纤维

新型碳材料 1987年第3期 43-47页

作者： d.d.edie N.K.Fox 范晓波

工业上生产碳纤维主要是采用PAN和石油沥青为原料,PAN基碳纤维的横载面通常为园形或哑铃形的,它取决于生产过程中凝固过程的性质。沥青基纤维是熔融法纺丝的,因此象其它熔纺纤维一样,可以由挤压成形,形成各种非园形的纤锥。在本文中,用... 详细信息

工业上生产碳纤维主要是采用PAN和石油沥青为原料,PAN基碳纤维的横载面通常为园形或哑铃形的,它取决于生产过程中凝固过程的性质。沥青基纤维是熔融法纺丝的,因此象其它熔纺纤维一样,可以由挤压成形,形成各种非园形的纤锥。在本文中,用石油沥青制备的原料熔融纺制了三叶形和八叶形碳纤维。这些非园形纤维,用园形碳纤维加工中使用的典型条件下进行予氧化和碳化,然后将其模量,强度和结构与作为对照物制造的园形纤维进行比较,发现非园形碳纤维具有独特的结构,比园形纤维具有更高的强度和模量。

关键词：纤维模量纺制三叶形碳化温度微观结构熔融纺丝装置

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

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Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： danko Jeremic Lydia Jiménez-díaz Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(Ad)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in Ad,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Remaking a connection:molecular players involved in post-injury synapse formation

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Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： diogo Tomé Ramiro d.Almeida iBiMEd-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma depends not only on axon regeneration or compensatory sprouting of uninjured fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several studies have successfully promoted long-distance axonal regeneration in distinct CNS injury models,none of them have resulted in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we discuss how our understanding of the mechanisms that instruct synapse formation in the injured nervous system may contribute to the design of new strategies to promote functional restoration in traumatic CNS disorders.

关键词： viable injury instru

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report

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Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Goldschmidt-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Adriana Brooks Risset Silvera Alexander J.P.Goldschmidt damien d.Pearse W.dalton dietrich Allan d.Levi James d.Guest Miller School of Medicine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzady International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and function of motor neurons,axonal networks,and the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been *** case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles,marking,to our knowledge,the first instance of such *** 81-year-old male patient presented with a 1.5-year history of rapidly progressive amyotrophic lateral *** initial diagnosis,the patient underwent a combination of generic riluzole,sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and *** patient volunteered to participate in an FdA-approved single-patient expanded access treatment and received weekly intravenous infusions of allogeneic Schwann cell-derived exosomal vesicles to potentially restore impaired Schwann cell and motor neuron *** confirmed that cultured Schwann cells obtained from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared impaired(senescent)and that exposure of the patient’s Schwann cells to allogeneic Schwann cell-derived exosomal vesicles,cultured expanded from a cadaver donor improved their growth capacity in *** a period of observation lasting 10 weeks,during which amyotrophic lateral sclerosis Functional Rating Scale-Revised and pulmonary function were regularly monitored,the patient received weekly consecutive infusions of 1.54×1012(×2),and then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-derived exosomal vesicles diluted in 40 mL of dulbecco’s phosphate-buffered *** of the infusions were associated with adverse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

Biochemical dissection of STAT3 signaling in amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nadia d’Ambrosi department of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons,clinically marked by muscle atrophy and *** the clinical course is highly variable,the average time from the onset of symptoms to the need for respiratory support or death is 3-5 *** is the most prevalent motor neuron disease in adults,occurring at a rate of 2 per 100,000 individuals and affecting 5.4 per 100,000 individuals overall.

关键词： STAT3 dissection sclerosis

Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram d.dongale Atul C.Khot Chenjie Yao Nahyun Kim Tae Geun Kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea Computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory