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The Properties and Applications of MoS_2/Ti Composite Coatings in dry Cutting and Forming

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材料热处理学报 2004年第5B期25卷 894-898页

作者： XiaolingZhang HailinSun d.becker S.Wagner d.G.Teer TeerCoatingsLtd. WestStineHouseBerryHillIndustrialEstateDroitwichWorcestershireUK InstituteforMetalFormingTechnology stuttgartUniversityStuttgartGermany

MoSi/Ti composite coatings (MoST?), have been deposited by a closed-field unbalanced magnetron sputter ion-plating system. The high ion-current densities at low substrate bias voltage of the system ensures that the MoST? coatings are characteristic of dense coherent structures, with high adhesion (critical scratch load above 120 N), high load bearing capacity up to 5 GPa., low friction (0.02-0.1), high wear resistance (less than 4xlO"17 m3/N m) even at a relative humidity of 40%, and high temperature resistance up to 350 °C. The successful applications of MoST? coatings in large- scale productions for dry cutting and forming, with increasing lifetime and productivity are presented.

关键词： MoS2/Ti复合涂层干切割低摩擦力磁控管溅射

通过卡那霉素选择体系再生可育小麦转基因植株

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自然科学进展（国家重点实验室通讯） 2001年第5期11卷 486-491页

作者：徐子勤 d.becker H.Lrz 西北大学生物技术省重点实验室 Institut fur Allgemeine Botanik Universita HamburgHamburg D-22609Germany

使用卡那霉素作为选择剂建立起一套有效的小麦转化体系,预培养3d的未成熟胚在基因枪轰击前后进行高渗处理,轰击后于26℃、黑暗条件培养2周,然后用150mg/L硫酸卡那霉素选择培养2周,再转至含150mg/L硫酸卡那霉素的再生培养基进行光照培养... 详细信息

使用卡那霉素作为选择剂建立起一套有效的小麦转化体系,预培养3d的未成熟胚在基因枪轰击前后进行高渗处理,轰击后于26℃、黑暗条件培养2周,然后用150mg/L硫酸卡那霉素选择培养2周,再转至含150mg/L硫酸卡那霉素的再生培养基进行光照培养。再生植株在温室中长出2～3片新叶后用2.5％硫酸卡那霉素水溶液喷洒;4周内,非转化体完全白化并枯萎,而转基因植株生长正常,用水稻Actinl启动子控制nptⅡ基因,卡那霉素选择体系的平均转化频率达到2.6％,高渗处理明显促进瞬间表达效果和稳定转化频率。目前已得到23个转基因小麦株系,大多数已经产生种子。Southern分析表明这些转基因株系均整合有不同拷贝的nptⅡ基因。

关键词：卡那霉素选择预培养高渗处理可育转基因小麦基因枪

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Molecular Plant 2012年第4期5卷 951-954页

作者： Giuseppe Ortu Raffaella Balestrini Patricia A. Pereira Jorg d. becker Helge Kuste Paola Bonfante department of Life Science and Systems Biology University of Torino Italy Istituto per la Protezione delle Piante--CNR Torino Italy Instituto Gulbenkian de Ciencia 2780-156 Oeiras Portugal Institut for Pflanzengenetik Leibniz Universitat Hannover Herrenhauser Str. 2 D-30419 Hannover Germany

dear Editor, Phytohormones are essential regulators of plant develop- ment, but their role in the signaling processes between plants and fungi during arbuscular mycorrhizal （AM） establishment is far from being understood （Ludwig-M011er, 2010）. AM coloni- zation leads to extensive effects on host metabolism, as revealed by transcriptome studies of AM plants （Hogekamp et al., 2011）. Some genes have been specified as an AM core set, since they are mycorrhizal-responsive, irrespective of the identity of the plant,

关键词： AM真菌植物激素相关基因早期阶段调节过程生物合成相互作用赤霉素

质粒dNA物理形态和其它因素对获得可育转基因小麦的影响

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实验生物学报 2001年第3期34卷 183-189页

作者：徐子勤 d.becker H.Lrz 西北大学生物技术省重点实验室西安710069 德国汉堡大学普通植物学研究所汉堡d22609

本工作分析了不同形态质粒dNA和未成熟胚高渗透压处理对基因枪小麦转化体系的适用性。高渗处理对瞬间表达和转基因小麦的再生均有明显的促进作用。轰击之前对质粒dNA进行变性处理导致瞬间表达反应大幅度下降,但稳定转化频率(指从100个... 详细信息

本工作分析了不同形态质粒dNA和未成熟胚高渗透压处理对基因枪小麦转化体系的适用性。高渗处理对瞬间表达和转基因小麦的再生均有明显的促进作用。轰击之前对质粒dNA进行变性处理导致瞬间表达反应大幅度下降,但稳定转化频率(指从100个轰击未成熟胚得到的再生可育转基因植株数)与双链dNA相差不大。使用单链质粒dNA、线性双链质粒dNA和环状双链质粒dNA均可以得到转基因小麦植株。迄今已得到26个不同的转基因冬小麦株系和4个不同的转基因春小麦株系。这些转基因小麦大多数已产生种子,几个春小麦株系已获第二代种子。

关键词：转基因小麦质粒dNA 物理形态稳定转化育性

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组织协调成像和对比成像改善肝转移的诊断?

Oncology and Translational Medicine 2000年第6期17卷 59-60页

作者： d.becker d.Strobel E.G.Hahn 同济医科大学附属同济医院

借助传统的超声检查,对有些占位病变,特别是小的占位病变不能发现,即使能够发现病变,但是往往因为分辨率不足而不能确诊。这对检查者来说是一个难题。通过组织协调成像和对比成像可以提高对比度,改善成像质量。这种新的超声检查技术,已... 详细信息

借助传统的超声检查,对有些占位病变,特别是小的占位病变不能发现,即使能够发现病变,但是往往因为分辨率不足而不能确诊。这对检查者来说是一个难题。通过组织协调成像和对比成像可以提高对比度,改善成像质量。这种新的超声检查技术,已经应用于肝脏疾

关键词：超声技术占位病变组织协调

构词法对无意识加工的影响——中德数字启动效应的比较研究

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心理科学 1993年第1期16卷 8-14页

作者：马红骊方芸秋 G.Luer U.Laβ d.becker R.Heuermann 华东师范大学心理系 Georg August Universitat GottingenGermany

本文采用客观觉察阈值作为启动刺激呈现时间、以数字(阿拉伯数字)和数词(以中、德两种文字写出的数词)为刺激比较研究了在掩蔽刺激条件下中国与德国被试的启动效应.结果表明:1)中国被试的启动效应显著,在德国被试中未发现显著的启动效应... 详细信息

本文采用客观觉察阈值作为启动刺激呈现时间、以数字(阿拉伯数字)和数词(以中、德两种文字写出的数词)为刺激比较研究了在掩蔽刺激条件下中国与德国被试的启动效应.结果表明:1)中国被试的启动效应显著,在德国被试中未发现显著的启动效应;2)除数字—数字刺激组外,中国被试的启动效应显著地大于德国被试;3)中国被试的数词—数字刺激组比其他三个刺激组产生的启动效应大。我们从无意识加工特征、构词法的差异以及并行—连续加工理论的观点对上述结果分别进行了讨论.

关键词：构词法无意识加工启动效应

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巨大嵌壁胆囊结石的超声波碎石疗法

放射学实践 1991年第1期6卷 26-29页

作者： Christoph d.becker Robert G.Gibney J.Stephen Fache V.Allen Rowley M.G.McLoughlin Burhenne H.Joachim 武卫国胡仁昭 departments of Radiology and Urology University of British Columbia and Vancouver General Hospital Canada 同济医科大学附属同济医院

当急性胆囊炎患者手术危险性较大或解剖关系不清楚时,可以用胆囊造瘘术代替胆囊切除术,胆囊结石的取出或通过外科手术,或者以后在X线监视下由放射科医生完成,后者使急性炎症期的手术创伤降至最小。我院对36例手术高危的且伴有多种并发... 详细信息

当急性胆囊炎患者手术危险性较大或解剖关系不清楚时,可以用胆囊造瘘术代替胆囊切除术,胆囊结石的取出或通过外科手术,或者以后在X线监视下由放射科医生完成,后者使急性炎症期的手术创伤降至最小。我院对36例手术高危的且伴有多种并发症的老年患者进行了此种卓有成效的治疗。尽管放射科医生用或不伴用机械碎石法在多数病例可取出结石碎片,但是对特别巨大的嵌壁结石的取出还存在着技术上的困难。下面报道的三例此类胆囊结石均采用超声波碎石法成功取出结石。

关键词：胆结石超声波碎石

Optical probing of ultrafast laser-induced solid-to-overdense-plasma transitions

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Light(Science & Applications) 2024年第5期13卷 973-984页

作者： Yasmina Azamoum Georg Alexander becker Sebastian Keppler Guillaume duchateau Stefan Skupin Mickael Grech Fabrice Catoire Sebastian Hell Issa Tamer Marco Hornung Marco Hellwing Alexander Kessler Franck Schorcht Malte Christoph Kaluza GSI Helmholtzzentrum für Schwerionenforschung Planckstr.164291 DarmstadtGermany. Helmholtz Institute Jena Fröbelstieg 307743 JenaGermany. Institute of Optics and Quantum Electronics Friedrich-SchillerUniversität JenaMax-Wien-Platz 107743 JenaGermany. CEA-CESTA 15 Avenue des SablièresCS6000133116 Le BarpCedexFrance Institut Lumière Matière UMR 5306-CNRSUniversitéde Lyon 169622 VilleurbanneFrance. LULI CNRSCEASorbonne UniversitéInstitut Polytechnique de ParisPalaiseauFrance. Universitéde Bordeaux-CNRS-CEA CELIAUMR 5107 TalenceFrance

Understanding the solid target dynamics resulting from the interaction with an ultrashort laser pulse is a challenging fundamental multi-physics problem involving atomic and solid-state physics,plasma physics,and laser *** of the initial interplay of the underlying processes is essential to many applications ranging from lowpower laser regimes like laser-induced ablation to high-power laser regimes like laser-driven ion *** the properties of the so-called pre-plasma formed as the laser pulse’s rising edge ionizes the target is complicated from the theoretical and experimental point of view,and many aspects of this laser-induced transition from solid to overdense plasma over picosecond timescales are still open *** the one hand,laser-driven ion acceleration requires precise control of the pre-plasma because the efficiency of the acceleration process crucially depends on the target properties at the arrival of the relativistic intensity peak of the *** the other hand,efficient laser ablation requires,for example,preventing the so-called“plasma shielding”.By capturing the dynamics of the initial stage of the interaction,we report on a detailed visualization of the pre-plasma formation and ***-thin diamond-like carbon foils are shown to transition from solid to plasma during the laser rising edge with intensitiesd probe transmission measurements evidence sub-picosecond dynamics of an expanding plasma with densities above 10^(23)cm^(−3)(about 100 times the critical plasma density).The complementarity of a solid-state interaction model and kinetic plasma description provides deep insight into the interplay of initial ionization,collisions,and expansion.

关键词： laser acceleration solid

Metabolic collaboration between cells in the tumor microenvironment has a negligible effect on tumor growth

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The Innovation 2024年第2期5卷 107-114页

作者： Johan Gustafsson Fariba Roshanzamir Anders Hagnestål Sagar M.Patel Oseeyi I.daudu donald F.becker Jonathan L.Robinson Jens Nielsen department of Life Sciences Chalmers University of TechnologySE-41296 GothenburgSweden Hagnesia AB SE-43854 HindåsSweden department of Biochemistry and Redox Biology Center University of Nebraska-LincolnLincolnNE 68588USA BioInnovation Institute DK2200 CopenhagenDenmark

The tumor microenvironment is composed of a complex mixture of different cell types interacting under conditions of nutrient deprivation,but the metabolism therein is not fully understood due to difficulties in measuring metabolic fluxes and exchange of metabolites between different cell types in ***-scale metabolic modeling enables estimation of such exchange fluxes as well as an opportunity to gain insight into the metabolic behavior of individual cell ***,we estimated the availability of nutrients and oxygen within the tumor microenvironment using concentration measurements from blood together with a metabolite diffusion *** addition,we developed an approach to efficiently apply enzyme usage constraints in a comprehensive metabolic model of human *** combined modeling reproduced severe hypoxic conditions and the Warburg effect,and we found that limitations in enzymatic capacity contribute to cancer cells’preferential use of glutamine as a substrate to the citric acid ***,we investigated the common hypothesis that some stromal cells are exploited by cancer cells to produce metabolites useful for the cancer *** identified over 200 potential metabolites that could support collaboration between cancer cells and cancer-associated fibroblasts,but when limiting to metabolites previously identified to participate in such collaboration,no growth advantage was *** work highlights the importance of enzymatic capacity limitations for cell behaviors and exemplifies the utility of enzyme-constrained models for accurate prediction of metabolism in cells and tumor microenvironments.

关键词： metabolism effect limitations