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Utilizing Instilling Negative Pressure Wound Therapy with Vashe Wound Solution for an Infected Sternal Dehiscence: A Case Report

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Surgical Science 2023年第3期14卷 231-239页

作者： Linnea T. m.uro courtney m. janowski m.riah J. janowski Adalberto C. Gonzalez Eugene J. Sidoti Luis G. Fernandez Paul J. Kim.m.rc R. m.tthews Valleywise m.dical Center Department of Surgery Phoenix Arizona Departm.nt of Surgery Division of Trauma Surgery/Surgical Critical Care University of Texas Health Science Center Tyler Texas The University of Texas Tyler School of Medicine Endowed Chair in Trauma Surgery Tyler Texas Traum. Wound Care UT Health East Tyler Texas Departm.nt of Surgery University of Texas Medical Branch Galveston Texas m.dicine and Nursing University of Texas Arlington Texas Departm.nt of m.dical Education Health Science Center Tyler Texas Departm.nt of Physician Assistant Studies School of Health Professions University of North Texas Fort Worth Texas ACS National Com.ittee on Traum. Chicago USA Plastic Surgery Department of Surgery University of Texas Southwestern Dallas Texas University of Arizona & Creighton University Schools of m.dicine The Arizona Burn Center Phoenix Arizona

Utilization of negative pressure wound therapy with instillation (NPWTi) for sternal dehiscence wounds secondary to sternal wound infection after surgery has becom. an accepted therapy. NPWTi accelerates wound healing through m.crostrain, m.crostrain, and cyclic fluid instillation. Wounds benefit from.additional superficial infection control with the rem.val of m.croorganism., the release of proinflam.atory m.diators, stim.lation of angiogenesis, as well as m.chanical debridem.nt. However, very few cases of utilizing NPWTi in the treatm.nt of sternal wound infections have been reported in the literature. This case study describes the use of NPWTi with hypochlorous acid for the treatm.nt of a sternal wound infection.

关键词： Negative Pressure Wound Therapy with Instillation NPWT NPWTi NPWT with Dwell Hypochlorous Acid Vashe Wound Solution Sternal Dehiscence

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Utilizing Instilling Negative Pressure Wound Therapy with Vashe Wound Solution for an Infected Sternal Dehiscence: A Case Report

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Surgical Science（外科学） 2023年第3期

作者： Linnea T. m.uro courtney m. janowski m.riah J. janowski Adalberto C. Gonzalez Eugene J. Sidoti Luis G. Fernandez Paul J. Kim.m.rc R. m.tthews

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Effect of liner and porcelain application on zirconia surface structure and com.osition

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International Journal of Oral Science 2016年第3期8卷 164-171页

作者： Tariq F Alghazzawi Gregg m.janowski Departm.nt of Prosthetic Dental Sciences College of DentistryTaibah University Departm.nt of m.terials Science and Engineering School of EngineeringThe University of Alabama at Birmingham

The purpose of this study was to determ.ne if there is an effect of liner and porcelain application （layering and pressing techniques） on the surface of yttria-stabilized tetragonal zirconia polycrystals （Y-TZP）, which were exposed to perm.tations of liner, layered porcelain, and pressed porcelain. Scanning electron m.croscope （SEm./energy dispersive spectroscope （EDS） was used to identify changes in com.osition and m.crostructure after rem.ving liner and porcelain with hydrofluoric acid. Sim.lated aging was also conducted to determ.ne the effect of liner and porcelain on low-tem.erature degradation. The control group had a typical equiaxed grain structure, referred to as unaffected. When covered with liner or porcelain, som. areas changed in structure and com.osition and were term.d affected. The frequency of affected sbructure decreased when liner was covered with either layered porcelain or pressed porcelain. There were statistical differences （P〈0.05） in the com.osition between affected and unaffected for zirconium.（layered porcelain with liner： affected = 60% （0.8%）（m.m., unaffected = 69% （4%）, layered porcelain without liner： affected = 59% （3%）, unaffected = 65% （3%）） and oxygen （layered porcelain with liner： affected = 35% （2%）, unaffected = 26% （4%）, layered porcelain without liner： affected = 35% （3%）, unaffected = 30% （2%））. However, there were statistical differences （P〈0.05） in the com.osition for zirconium.and oxygen of the aged layered porcelain without liner only. The liner should not be used before porcelain application, especially when using the layering technique for zirconia restorations. Furtherm.re, pressing should be considered the technique of choice over layering.

关键词： aging coefficient of therm.l expansion energy dispersive spectroscopy layering of porcelain pressing of porcelain scanning electron m.croscope zirconia

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nflam.asom.s in cancer： a double-edgecl sword

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Protein & Cell 2014年第1期5卷 12-20页

作者： Ryan Kolb Guang-Hui Liu Ann m. janowski Fayyaz S. Sutterwala Weizhou Zhang Departm.nt of Pathology Carver College of Medicine University of Iowa Iowa City IA 52242 USA National Laboratory of Biom.crom.lecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China Gene Expression Laboratory Salk Institute for Biological Studies 10010 North Torrey Pines Road La Jolla CA 92037 USA Graduate Program.in Im.unology Carver College Of Medicine University of Iowa iowa City IA 52242 USA Departm.nt of Internal m.dicine Carver College of Medicine University of Iowa Iowa City IA 52242 USA Veterans Affairs m.dical Center Iowa City IA 52241 USA

Chronic inflam.atory responses have long been observed to be associated with various types of cancer and play decisive roles at different stages of cancer developm.nt. Inflam.asom.s, which are potent induc- ers of interleukin （IL）-I~ and IL-18 during infam.ation, are large protein com.lexes typically consisting of a Nod-like receptor （NLR）, the adapter protein ASC, and Caspase-1. During m.lignant transform.tion or cancer therapy, the inflam.asom.s are postulated to becom. activated in response to danger signals arising from.the tum.rs or from.therapy-induced dam.ge to the tum.r or healthy tissue. The activation of inflam.asom.s plays diverse and som.tim.s contrasting roles in cancer prom.tion and therapy depending on the specific con- text. Here we sum.arize the role of different inflam.a- som. com.lexes in cancer progression and therapy. Inflam.asom. com.onents and pathways m.y provide novel targets to treat certain types of cancer; however, using such agents should be cautiously evaluated due to the com.lex roles that inflam.asom.s and pro- inflam.atory cytokines play in im.unity.

关键词： inflam.asom. cancer inflam.ation

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Evaluation of zirconia–porcelain interface using X-ray diffraction

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International Journal of Oral Science 2015年第3期7卷 187-195页

作者： Tariq F Alghazzawi Gregg m.janowski Departm.nt of m.terials Science and Engineering School of Engineering The University of Alabama at Birmingham Departm.nt of Prosthetic Dental Sciences College of Dentistry Taibah University

The aim.of this study was to determ.ne if accelerated aging of porcelain veneering had an effect on the surface properties specific to a tetragonal-to-m.noclinic transform.tion（Tm.） of zirconia restorations. Thirty-six zirconia sam.les were m.lled and sintered to sim.late core fabrication followed by exposure to various com.inations of surface treatm.nts including as-received（control）,hydrofluoric acid（HF）, application of liner plus firings, application of porcelain by m.nual layering and pressing with firing, plus accelerated aging. The quantity of transform.d tetragonal to m.noclinic phases was analyzed utilized an X-ray diffractom.ter and one-way analysis of variance was used to analyze data. The control sam.les as provided from.the dental laboratory after m.lling and sintering process had no Tm.（X m. 0）. There was an effect on zirconia sam.les of HF application with Tm.（X m. 0.8%） and liner plus HF application with Tm.（X m. 8.7%）. There was an effect of aging on zirconia sam.les（no veneering） with significant Tm.（X m. 70.25%）. Both m.nual and pressing techniques of porcelain applications reduced the Tm.（m.nual, X m. 4.41%, pressing,X m. 11.57%）, although there was no statistical difference between them. It can be concluded that sim.lated applications of porcelain dem.nstrated the ability to protect zirconia from.Tm. after aging with no effect of a liner between different porcelain *** HF treatm.nt also caused Tm..

关键词： aging hydrofluoric acid m.noclinic pressing tetragonal X-ray diffraction

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大型公共运输中的热塑性组合框架结构的设计、制造和分析

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钢结构 2008年第2期23卷 76-77页

作者： Haibin Ning Uday Vaidya Gregg m. janowski George Husm.n

薄壁复合材料具有优越的性能,包括高强度、轻质、抗弯、抗剪性强等,因而经常用于大型交通领域。从目前的研究来看,已经设计、分析并制造出一种用于大型运输卡车的薄壁复合热塑组合结构来代替传统的金属结构。考虑了三种横截面构造,分别... 详细信息

薄壁复合材料具有优越的性能,包括高强度、轻质、抗弯、抗剪性强等,因而经常用于大型交通领域。从目前的研究来看,已经设计、分析并制造出一种用于大型运输卡车的薄壁复合热塑组合结构来代替传统的金属结构。考虑了三种横截面构造,分别是矩形、V字形、C形,对比了编织方向在(0/90)6,[±45/(0/90)2]s及[±45/(0/90)]3等不同的复合材料层合结构。该结构选用碳纤/聚亚苯硫化物(carbon/PPS)作为原材料,采用单模复合成型。通过面内冲压试验,验证了碳/PPS组合结构有限元分析结果,论证了薄壁碳/PPS热组合结构制造策略的设计理念。

关键词：热塑性复合材料碳纤维聚亚苯硫化物 (PPS) 大型交通薄壁结构

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3D printing-based frugal m.nufacturing of glass pipettes for m.nim.lly invasive delivery of therapeutics to the brain

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Neuroprotection 2023年第1期1卷 58-65页

作者： Guanda Qiao David Gulisashvili Anna Jablonska Guiling Zhao m.roslaw janowski Piotr Walczak Yajie Liang Departm.nt of Diagnostic Radiology and Nuclear m.dicine University of Maryland School of MedicineBaltimoreMarylandUSA Laboratory of m.lecular Cardiology Department of PhysiologyCenter for Biomedical Engineering and TechnologyUniversity of Maryland School of MedicineBaltimoreMarylandUSA

Objective:Intracerebral delivery of agents in liquid form.is usually achieved through com.ercially available and durable m.tal ***,their size and texture m.y contribute to m.chanical brain *** pipettes with a thin tip m.y significantly reduce injection-associated brain dam.ge but require access to prohibitively expensive program.able pipette *** study is to rem.ve the econom.c barrier to the application of m.nim.lly invasive delivery of therapeutics to the brain,such as chem.cal com.ounds,viral vectors,and ***:We took advantage of the rapid developm.nt of free educational online resources and em.rging low-cost 3D printers by designing an affordable pipette puller(APP)to rem.ve the cost ***:We showed that our APP could produce glass pipettes with a sharp tip opening down to 20μm.or less,which is sufficiently thin for the delivery of therapeutics into the brain.A pipeline from.pipette pulling to brain injection using low-cost and open-source equipm.nt was established to facilitate the application of the ***:In the spirit of frugal science,our device m.y dem.cratize glass pipette-puling and substantially prom.te the application of m.nim.lly invasive and precisely controlled delivery of therapeutics to the brain for finding m.re effective therapies of brain diseases.

关键词： 3D-printable brain injection frugal science glass pipette pulling

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用于大型公共交通的热塑性复合夹芯板结构设计与制造

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钢结构 2008年第2期23卷 74-74页

作者： Haibin Ning Gregg m. janowski Uday K. Vaidya George Husm.n

轻质运输工具可以提高燃料的燃烧效率、降低运行费用,在大型公共交通系统中更为明显。轻质复合材料,如玻璃纤维增强聚合物,被用来替代传统的钢材和铝合金。介绍了采用热塑性复合材料的大型公共汽车侧板的设计、分析研究和制造。设计了... 详细信息

轻质运输工具可以提高燃料的燃烧效率、降低运行费用,在大型公共交通系统中更为明显。轻质复合材料,如玻璃纤维增强聚合物,被用来替代传统的钢材和铝合金。介绍了采用热塑性复合材料的大型公共汽车侧板的设计、分析研究和制造。设计了一种由E-玻璃纤维/聚丙烯表面覆盖和聚丙烯蜂窝核心构成的复合夹芯板,具有轻质,高强和良好的吸能性能。夹芯板的设计和分析采用Pro/E、Hy-perm.sh、ANSYS等软件进行。单一的膜结构用于制造玻璃纤维/聚丙烯表面覆盖,表面覆盖的微结构分析证明此过程可以保证很好的固结。表面覆盖与核心材料被牢固地结合起来并经过了模型测试。荷载达到11.7kN时由于粘结失效导致夹芯板破坏。夹芯板的静载能力已满足美国公共运输协会(AP-TA)的要求。与传统的铝面钢结构卡车相比,热塑性复合材料制造的夹芯板减轻了55%的重量。

关键词：热塑性复合材料夹芯板结构玻璃纤维/聚乙烯大型交通系统膜结构

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On new classes of strongly janowski type functions of com.lex order

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Applied m.them.tics(A Journal of Chinese Universities) 2023年第1期38卷 89-99页

作者： Khalil Ahm.d Khudija Bibi m.Sajjad Shabbir Departm.nt of m.them.tics Air UniversityPAF-ComplexSector E-9IslamabadPakistan Departm.nt of m.them.tics Faculty of Basic and AppliedInternational Islamic University IslamabadPakistan Departm.nt of m.them.tics University of Poonch RawalakotAzad Kashmir 12350Pakistan

We investigate som. new subclasses of analytic functions of janowski type of com.lex *** also study inclusion properties,distortion theorem.,coefficient bounds and radius of convexity of the ***,analytic properties of these classes under certain integral operator are also *** findings are m.re com.rehensive than the existing results in the literature.

关键词： subordination janowski function starlike function convex function com.lex order

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