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Influence of pouring temperature on solidification behavior, microstructure and mechanical properties of sand-cast mg-10Gd-3Y-0.4Zr alloy

1999年

作者： conrad Phillip Kottak

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Transactions of Nonferrous metals Society of China 2015年第2期25卷 363-374页

作者：庞松吴国华刘文才张亮张扬 Hans conrad 丁文江上海交通大学轻合金精密成型国家工程研究中心与金属基复合材料国家重点实验室上海200240 Department of materials Science and Engineering North Carolina State University

Influence of the pouring temperature ranging from 680 to 780 ℃ on the solidification behavior, the microstructure and mechanical properties of the sand-cast mg-10Gd-3Y-0.4Zr alloy w.s investigated. It w.s found that the nucleation undercooling of the a-mg phase increased from 2.3 to 6.3 ℃. The average a-mg grain size increased from 44 to 71 μm, but then decreased to 46 μm. The morphology of the eutectic compound transformed from a continuous netw.rk into a discontinuous state and then subsequently into an island-like block. The volume fraction of β-mg_24RE_5 phase increased and its morphology transformed from particle into rod-like. The increase in pouring temperature increased the solute concentration. YS increased from 138 to 151 mPa, and UTS increased from 186 to 197 mPa. The alloy poured at 750 ℃ had optimal combining strength and ductility. The fracture surface mode transformed from quasi-cleavage crack into transgranular fracture, all plus the dimple-like fracture, w.th the micro-porosity and the re-oxidation inclusion as major defects. The average a-mg grain size played a main role in the YS of sand-cast mg-10Gd-3Y-0.4Zr alloy, besides other factors, i.e. micro-porosity, morphology of eutectic compounds, re-oxidation inclusion and solute concentration.

关键词： sand-cast mg alloys solidification microstructure mechanical properties

The research group of Guoquan Liu revealed that photodynamic therapy drove a distinct ferroptosis-like cell death pathw.y in tumor cells

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Journal of Chinese Pharmaceutical Sciences 2021年第7期30卷 617-618页

作者： Shui S. Zhao Z. w.ng H. conrad m. Liu G. 北京大学药学院天然药物及仿生药物国家重点实验室

近日,北京大学药学院天然药物及仿生药物国家重点实验室的刘国全团队在国际"氧化还原生物学与医学协会(Sf RBm)"的官方期刊《Redox Biology》在线发表了题为"Non-enzymatic lipid peroxidation initiated by photodynamic therapy drive... 详细信息

近日,北京大学药学院天然药物及仿生药物国家重点实验室的刘国全团队在国际"氧化还原生物学与医学协会(Sf RBm)"的官方期刊《Redox Biology》在线发表了题为"Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathw.y"的研究工作。

关键词：光动力疗法北京大学药学院细胞死亡 death 氧化还原

Polycrystalline Si thin-film solar cells w.th absorber layers grow. at temperatures below.600℃ by ECRCVD

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Polycrystalline Si thin-film solar cells with absorber layer...

Evaluation of methods for Dissemination of Prostate Cancer Survivorship Guidelines: A Survey of Primary Care Providers

第十五届国际光伏科学与工程大会

作者： B.Rau J.Schneider E.conrad S.Gall w.Fuhs Hahn-meitner Institut Berlin Kekuléstr.5D-12489 Berlin Germany Hahn-meitner Institut Berlin Kekuléstr.5D-12489 Berlin Germany Hahn-meitner Institut Berlin Kekuléstr.5D-12489 Berlin Germany Hahn-meitner Institut Berlin Kekuléstr.5D-12489 Berlin Germany Hahn-meitner Institut Berlin Kekuléstr.5D-12489 Berlin Germany

＜正＞ Solar cells w.re prepared w.th absorber layers grow. below.600℃on both polycrystalline Si seed layers on glass and Si（100） w.fers. The seed layers w.re formed by the aluminum-induced layer exchange process （ALILE） based on the aluminum-induced crystallization of amorphous Si. To form a p-type absorber layer （～2μm） the seed layers w.re thickened by ECRCVD using silane and diborane. A thin, highly phosphorous-doped amorphous emitter layer w.s deposited. w. discuss the influence of absorber layer post-treatments on the solar cell parameters. w. achieved open-circuit voltages of up to 378mV for solar cells on seed layers by the application of defect annealing and hydrogen passivation. On highly-doped, p-type CZ-Si（100） w. obtained an open-circuit voltage of 458mV even w.thout any additional treatments of the absorber layer. These results are very encouraging for low.temperature preparation of solar cells.

关键词： Silicon Thin-film Solar Cells Seed Layer Low.temperature Epitaxy ECRCVD

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Open Journal of Urology 2013年第3期3卷 165-172页

作者： Shaw. J. mendonca manijeh Berenji conrad m. Tobert Heather Stetler Deb Bisel Brian R. Lane Cancer Program Spectrum Health Hospital System Grand Rapids USA Department of Epidemiology University of Michigan Ann Arbor USA Department of Surgery Michigan State University College of Human Medicine Grand Rapids USA

Objectives: To assess potential know.edge gaps betw.en primary care providers (PCPs) and cancer specialists, michigan Cancer Consortium guidelines w.re developed and disseminated statew.de. w. evaluated the impact of dissemination of these guidelines on PCP attitudes and beliefs regarding management of prostate cancer (PC) post-treatment sequelae. methods: Guidelines w.re disseminated via hard-copy and w.b-link mailed to 12,000 michigan PCPs in 2009, and via 5 CmE presentations to 181 PCPs in 2010-2011. 132 initial surveys w.re collected from CmE attendees and 549 follow.up surveys w.re received 20 months after the initial mailing. Results: Surveyed PCPs indicated erectile dysfunction (88%), incontinence (84%), anxiety (54%) and fear of the unknow. (50%) as frequent post-treatment sequelae. A minority of PCPs (≤41%) felt “very comfortable” assessing PC patients for ten post-treatment sequelae at the initial survey, w.ich increased by up to 27% on follow.up survey. 93% of PCPs that received guidelines by mail and CmE presentation had incorporated them into practice, compared w.th 72% of PCPs that received guidelines solely by mailing. Similarly, a greater proportion reported practice pattern changes (65% vs. 34%, p = 0.0003). A higher proportion felt CmE events (69% vs. 57%) and expert presentations (64% vs. 44%) w.re “very effective”, w.en comparing attendees and non-attendees. Conclusions: Guideline distribution resulted in increased comfort w.th survivorship issues and incorporation into the practices of the majority of PCPs surveyed. A greater impact w.s observed in PCPs that attended a CmE presentation than in those that received guidelines only by mailing.

关键词： Prostate Cancer Survivorship Survey Primary Care Physicians Guidelines

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固态恒流调制器的更新

现代雷达 1991年第2期13卷 81-86页

作者： George m.conrad 李文龙

两年前召开的第17届功率调制会议上,曾介绍过一个正交场放大管(CFA)调制器的革新方案,此方案现正在进行性能实验为生产作准备。本文介绍的内容是对上述设计方案的一种更新。为了提高效率并增强调制器的工作能力,需要对过去的方案作几处... 详细信息

两年前召开的第17届功率调制会议上,曾介绍过一个正交场放大管(CFA)调制器的革新方案,此方案现正在进行性能实验为生产作准备。本文介绍的内容是对上述设计方案的一种更新。为了提高效率并增强调制器的工作能力,需要对过去的方案作几处改进。本文简单地介绍了过去的论文内容,阐明了为便于生产对设计所作的改进,同时提供能表征其性能的测试结果。

关键词：固态恒流调制器

The push-pull principle:an electrostatic actuator concept for low.distortion acoustic transducers

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microsystems & Nanoengineering 2022年第6期8卷 181-194页

作者： Bert Kaiser Hermann A.G.Schenk Lutz Ehrig Franziska w.ll Jorge m.monsalve Sergiu Langa michael Stolz Anton melnikov Holger conrad David Schuffenhauer Harald Schenk Fraunhofer Institute for Photonic microsystems IPmS DresdenGermany Arioso Systems GmbH since Sep.1st 2022:BOSCH Sensortec GmbHDresdenGermany Chair of micro and Nano Systems Brandenburg University of Technology Cottbus-SenftenbergCottbusGermany

Electrostatic actuators are of particular interest for microsystems(mEmS),and in particular for mEmS audio transducers for use in advanced true w.reless *** are attractive because of their typically low.electrical capacitance and because they can be fabricated from materials that are compatible w.th standard complementary metal-oxide semiconductor(CmOS)*** high audio performance and in particular low.harmonic distortion(THD)the implementation of the push-pull principle provides strong *** an arrangement of three electrodes in a conjunct moving configuration on a beam,w. demonstrate here for the first time a balanced bending actuator incarnating the push-pull principle operating at low.*** first design already exhibits a harmonic distortion as low.as 1.2%at 79 dB using a signal voltage of only 6 V_(p) and a constant voltage of only±10 V_(dc) in a standard acoustic measurement ***,exceeding our previously reported approach in all three key performance indications at the same *** expect that our novel electrode configurations w.ll stimulate innovative electrostatic actuator developments for a broad range of *** this paper w. report the basic theory,the fabrication and the performance of our novel actuator design acting as an audio transducer.

关键词： distortion push electrostatic

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富有魅力的分子计算机

系统工程与电子技术 1987年第7期 60-68页

作者： m.conrad 叶信安蔡文廷

(生物)分子计算机是计算机发展的一个令人神往的方向。七十年代产生了生物工程,近年来在基因重组技术、蛋白质工程、生物敏感器等方面有了飞跃发展。八十年代兴起了生物电子学。前沿科学之间的撞击迸发出分子计算机这一明亮耀眼的火花,... 详细信息

(生物)分子计算机是计算机发展的一个令人神往的方向。七十年代产生了生物工程,近年来在基因重组技术、蛋白质工程、生物敏感器等方面有了飞跃发展。八十年代兴起了生物电子学。前沿科学之间的撞击迸发出分子计算机这一明亮耀眼的火花,引起了全世界的注意。为了让广大科技人员了解分子计算机技术的发展概况,特将这篇深入浅出的专题报告翻译发表。

关键词：分子计算机敏感器可编程系统传感器计算机程序

Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review

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w.rld Journal of Clinical Cases 2014年第6期2卷 172-193页

作者： Robbie SR w.ods Esther m O'Regan Susan Kennedy Cara martin John J O'Leary conrad Timon Department of Otolaryn-gology Royal Victoria Eye and Ear Hospital Department of Histopa-thology St. James’s Hospital Department of Histopathology Royal Victoria Eye and Ear Hospital molecular Pathology Research Coombe Women and Infants University Hospital

Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, how.ver many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma w.s performed and information on the topic w.s gathered. In this article, w. present an extensive review.of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator w.th better overall survival than HPV-negative tumours. A distinct group of younger patients w.th limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. How.ver, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities.

关键词： Human papillomavirus Human papillomavirus Oropharynx Oropharyngeal Squamous cell carcinoma Head and neck Oncology

^(123)Ⅰ和^(99)Tc^m标记的吲哚类σ_2受体放射性示踪剂的设计、稳定化合物的合成及体外生物评价

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核化学与放射化学 2010年第2期32卷 99-105页

作者：李艳贾红梅 Deuther-conrad w.nnie Brust Peter Steinbach Joerg 刘伯里放射性药物教育部重点实验室北京师范大学化学学院北京100875 Forschungszentrum Dresden-Rossendorf Institute of Radiopharmacy/Neuroradiopharmaceutical Division04318 LeipzigGermany

设计了123Ⅰ和99Tcm标记的吲哚类σ2受体肿瘤放射性示踪剂,合成了其稳定化合物(Indole-Ⅰ和Indole-mAmA-Re)和标记前体(Indole-mAmA)。体外受体结合分析结果表明,化合物Indole-Ⅰ对σ1和σ2受体的抑制常数Ki值分别为(0.574±0.355)μmo... 详细信息

设计了123Ⅰ和99Tcm标记的吲哚类σ2受体肿瘤放射性示踪剂,合成了其稳定化合物(Indole-Ⅰ和Indole-mAmA-Re)和标记前体(Indole-mAmA)。体外受体结合分析结果表明,化合物Indole-Ⅰ对σ1和σ2受体的抑制常数Ki值分别为(0.574±0.355)μmol/L和(0.162±0.030)μmol/L(n=3),Indole-mAmA-Re对σ1和σ2受体的抑制常数Ki值分别为(3.75±2.22)μmol/L和(7.83±4.87)μmol/L(n=3)。成功制备了99Tcm-Indole-mAmA,纯化后经高效液相色谱法(HPLC)分析其放化纯大于90%。今后可在本文化合物的基础上通过结构优化,设计合成对σ2受体具有高亲和力和选择性的吲哚类SPECT肿瘤显像剂。

关键词：吲哚类配体 σ受体 99Tcm 123Ⅰ