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祛痘方提取物抗炎祛痘体外功效评价

上海医药 2024年第11期45卷 7-11,22页

作者：朱迎全朱聪聪董怡彤朱全刚上海市静安区中医医院药剂科上海200072 上海市皮肤病医院药剂科上海200443 上海中药外用制剂创新工程技术研究中心上海200443 上海修之泉生物科技有限公司上海200040

目的:体外评价祛痘方提取物的表皮屏障修复、抗炎、控油和抗菌功效。方法:分别通过检测对十二烷基硫酸钠(sodium dodecyl sulfate,SDS)诱导的HaCaT细胞损伤模型增殖的影响、对脂多糖诱导的RAW 264.7细胞一氧化氮生成的影响、对SZ95细胞... 详细信息

目的:体外评价祛痘方提取物的表皮屏障修复、抗炎、控油和抗菌功效。方法:分别通过检测对十二烷基硫酸钠(sodium dodecyl sulfate,SDS)诱导的HaCaT细胞损伤模型增殖的影响、对脂多糖诱导的RAW 264.7细胞一氧化氮生成的影响、对SZ95细胞增殖及其中性脂质合成的影响、对金黄色葡萄球菌和痤疮丙酸杆菌的抑制作用来评价祛痘方提取物的表皮屏障修复、抗炎、控油和抗菌功效。结果:祛痘方提取物能够提高SDS诱导的HaCaT细胞的存活率,抑制经脂多糖处理的RAW 264.7细胞分泌一氧化氮,促进SZ95细胞生长并抑制其中性脂质合成,抑制金黄色葡萄球菌和痤疮丙酸杆菌的活性。结论:祛痘方提取物具有显著的表皮屏障修复、抗炎、控油和抑菌功效,有望成为一种新的中药祛痘护肤品原料。

关键词：祛痘方提取物表皮屏障修复抗炎控油抑菌

Hot deformation characterization of as-homogenized Al-Cu-Li X2A66 alloy through processing maps and microstructural evolution

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Journal of Materials Science & Technology 2019年第10期35卷 2409-2421页

作者： Liwei Zhong Wenli Gao Zhaohui Feng Zheng Lu congcong zhu College of Materials Science and Engineering Hunan UniversityChangsha 410082China Institute of Aluminum Alloy Beijing Institute of Aeronautical MaterialsBeijing 100095China Beijing Engineering Research Center of Advanced Aluminum Alloys and Applications Beijing Institute of Aeronautical MaterialsBeijing 100095China

Uniaxial compression tests were carried out on an Al-Cu-Li alloy at a temperature range of 300–500℃ and a strain rate range of 0.001–10 s^-1. Four representative instability maps based on Gegel, AlexanderMalas(A-M), Kumar-Prasad(K-P) and Murty-Rao(M-R) criteria were constructed. Through formula deduction and microstructural observation, it can be concluded that M-R criterion is more accurate than K-P criterion, and the first two criteria are better than Gegel and A-M criteria. From a power dissipation map and a M-R instability map, the optimized processing parameters are 480–500℃/0.001–0.1 s^-1 and 420–480℃/0.1-1 s^-1. The corresponding microstructural analysis shows that dynamic recovery and partial dynamic recrystallization are main dynamic softening mechanisms. Transmission electron microscopy observation indicated that a large number of primary coarse T1(Al2 Cu Li) particles precipitated in the homogenized specimen. After deformation at 500℃, most of the primary T1 particles dissolved back into the matrix, and secondary fine T1 particles precipitated at deformation-induced dislocations, high angle grain boundaries and other dispersed particles.

关键词： Al-Cu-Li alloy Hot deformation Processing map Dynamic recrystallization Precipitate

Temperature sensing behavior of Tm^3+:1G4(a),1G4(b) in oxyfluoride glass ceramics containing BaYbxY1-xF5 nanocrystals

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Journal of Rare Earths 2020年第4期38卷 356-361页

作者： Rui zhu Ke Zhang congcong zhu Zhencai Li Qiuhong Min Dacheng Zhou Jianbei Qiu College of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China

Tm3+-doped transparent oxyfluoride glass ceramics containing BaYbxY((1-x))F5 nanocrystals were prepared via high temperature solid phase melting method,of which up-conversion emission is achieved by the Yb3+-mediated energy transfer *** required photon number of Tm3+ions emissions in BaYbxY(1-x)F5 nanocrystals was calculated through the luminescence spectra,revealing the strong dependence of energy transfer mechanism on Yb3+ions ***,based on the fluore scence intensity ratio technology,the effect of different energy transfer mechanism on the temperature sensitivity was investigated by the temperature-dependent luminescence intensity of thermally coupled energy levels of Tm3+:1G4(a),1G4(b).The obtained sensitivity decreases with the increase of Yb3+ions content,which is mainly attributed to the changes in photon absorption process of Tm^3+:1G4(b).

关键词： Tm^3+ BaYbxY(1-x)F5 Glass ceramics Up-conversion luminescence Temperature sensing Rare earths

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传统钩编花样设计与工艺虚拟仿真实验

纺织科技进展 2024年第2期46卷 56-58,66页

作者：郑攀朱聪聪丰瑞芳河南科技学院河南新乡453003 郑州工业应用技术学院郑州451100

针对钩编花样设计与工艺实验教学中存在的制作周期长、打样成本高、成品产出效率低、学生参与度低的问题,探索应用现代信息化技术和虚拟现实技术,构建以学生为主体、问题为导向、以虚促实为原则的钩编花样设计与工艺虚拟仿真实验。设计... 详细信息

针对钩编花样设计与工艺实验教学中存在的制作周期长、打样成本高、成品产出效率低、学生参与度低的问题,探索应用现代信息化技术和虚拟现实技术,构建以学生为主体、问题为导向、以虚促实为原则的钩编花样设计与工艺虚拟仿真实验。设计3个实验阶段、4个实验模块和13个主要交互性实验操作步骤,以期打破时空限制,提高实验效率和质量,激发学生学习和创作热情,提升学生实验操作能力、自主学习能力和创新能力,推动高校教学改革和发展,培养应用型专业人才。

关键词：传统钩编技艺花样设计与工艺虚拟仿真实验

Microstructure characteristics and mechanical properties of Al/Mg joints manufactured by magnetic pulse welding

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镁合金学报(英文) 2023年第7期11卷 2366-2375页

作者： congcong zhu Shiwei Xu Wenli Gao Yifan Meng Sen Lin Lu Dai College of Materials Science and Engineering Hunan UniversityChangsha 410082China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China Beijing Spacecrafts Beijing 100094China

The effective connection of 1050 Al and AZ31 Mg was realized by magnetic pulse *** maximum tensile-shear force of the dissimilar Al/Mg metal lap joint reached 97%of that of the 1050 Al alloy base material by optimizing the process *** microstructure of dissimilar Al/Mg welded joints was analysed by Scanning Electron Microscope(SEM),Energy Dispersive Spectrometer(EDS)and Electron Backscattered Diffraction(EBSD).The results show that the key to obtaining high shear strength of Al/Mg dissimilar metal joints is mainly due to the following two *** the one hand,grain refinement and element interdiffusion occur at the *** the other hand,no intermetallic compounds are formed at the interface.

关键词： Al/Mg dissimilarmaterials Magneticpulsewelding Mechanicalproperties Interface EBSD

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紫归润唇膏体内外抗炎功效评价

上海医药 2024年第11期45卷 3-6,22页

作者：朱聪聪罗楹黄梽楠朱全刚上海市皮肤病医院药剂科上海200443 上海中药外用制剂创新工程技术研究中心上海200443 上海中医药大学附属岳阳中西医结合医院皮肤科上海200437 上海市中医药研究院皮肤病研究所上海201203 中国药科大学中药学院南京211100

目的:体内外评价紫归润唇膏的抗炎功效。方法:建立脂多糖诱导的RAW 264.7细胞炎症模型,检测紫归醇提物对一氧化氮生成的影响。建立卡泊三醇诱导的特应性皮炎样小鼠模型,研究紫归润唇膏对小鼠耳皮肤厚度、耳皮肤炎症的严重程度、组织病... 详细信息

目的:体内外评价紫归润唇膏的抗炎功效。方法:建立脂多糖诱导的RAW 264.7细胞炎症模型,检测紫归醇提物对一氧化氮生成的影响。建立卡泊三醇诱导的特应性皮炎样小鼠模型,研究紫归润唇膏对小鼠耳皮肤厚度、耳皮肤炎症的严重程度、组织病理及安全性的影响。结果:25~200μg/mL紫归醇提物能够促进RAW 264.7细胞生长且显著降低一氧化氮水平。同时紫归润唇膏能够显著降低特应性皮炎样小鼠耳部厚度,降低湿疹面积及严重度指数(eczema area and severity index,EASI)评分,减少炎症细胞浸润,降低棘层增厚,改善小鼠耳廓皮损炎症情况,且对卡泊三醇诱导的特应性皮炎样小鼠肝脾肾无影响。结论:紫归润唇膏具有显著抗炎功效且具有安全性。

关键词：紫归润唇膏抗炎功效评价

Dynamic microstructure evolution and mechanical properties of dilute Mg-Al-Ca-Mn alloy during hot rolling

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Journal of Materials Science & Technology 2022年第34期129卷 1-14页

作者： Shiwei Xu congcong zhu Zhanhong Lin Chen Jin S.Kamado K.Oh-ishi Yun Qin College of Materials Science and Engineering Hunan UniversityChangsha 410082China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China Qinghai Salt Lake Teli Magnesium Co.Ltd. Xining 810000China Department of Mechanical Engineering Nagaoka University of TechnologyNagaoka 940-2188Japan Toyota Central R&D Labs. Inc.41-1 YokomichiNagakuteAichi 480-1192Japan Research Institute(R&D Centre) Baowu Steel Group CorporationShanghai 201900China

The dynamic microstructure and texture of dilute Mg-0.50Al-0.71Ca-0.33Mn(wt.%) during hot rolling at two slab temperatures were investigated by electron backscattered diffraction(EBSD) and high resolution transmission electron microscopy(HRTEM). The results show that the development of the rolling microstructures is to first form {10–12} extension twins in the original grains, thereby forming the extension-twinned regions, and then to further form {10–11}-{10–12} double twins and kinks in the extension-twinned regions, and finally to form continuous dynamic recrystallized(continuous DRXed)grains in the double twins and the cross parts of the shear-deformed coarse extension-twinned *** extension twins, double twins and kinks show a decisive effect on the formation of rolling *** number of {10–11}-{10–12} double twins and resultant the continuous DRX process are strongly affected by the rolling slab temperature and the reduction thickness per pass. By optimizing the rolling conditions, texture and microstructures of the multi-pass rolled Mg-Al-Ca-Mn alloy sheets are successfully modified. Although the total alloy content is only 1.5 wt.%, these Mg-Al-Ca-Mn alloy sheets show much higher strength than the commercial Mg-3Al-1 Zn(wt.%)(AZ31B) sheet.

关键词： Mg-Al-Ca-Mn alloy Hot rolling Dynamic recrystallization Texture control Mechanical properties

多场景下新型储能项目盈利模式分析及成本补偿机制建议

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中外能源 2024年第2期29卷 13-22页

作者：周楠潘炜祝聪聪岳芬李晨飞张兴中国华能集团有限公司北京100011 中关村储能产业技术联盟北京100190

新型储能是构建以新能源为主体的新型电力系统的重要支撑。新型储能的盈利模式与政策、市场机制息息相关,是决定储能能否大规模商业应用的关键。通过调研国内外典型地区新型储能项目的发展背景、配套政策和运营模式,开展多场景下新型储... 详细信息

新型储能是构建以新能源为主体的新型电力系统的重要支撑。新型储能的盈利模式与政策、市场机制息息相关,是决定储能能否大规模商业应用的关键。通过调研国内外典型地区新型储能项目的发展背景、配套政策和运营模式,开展多场景下新型储能盈利模式分析和对比研究。国外新能源配储在长期购电协议和税收抵免机制的共同作用下,已有较好的收益;国外现货市场、辅助服务市场比较完善,电网侧独立储能收益来源较丰富,加上一系列补贴政策,电网侧独立储能经济性较好。与国外相比,国内新能源配储、电网侧独立储能都存在收益来源少、收益不稳定、经济性差的问题;国内部分省份用户侧储能短期内收益较好。鉴于此,关于我国新型储能成本补偿机制,建议对电源侧储能准入条件、保障利用小时数、放电量补偿及可参与品种给予政策倾斜;在电网侧独立储能发展初期,出台容量租赁、电价补贴或容量补贴等政策,以促进其成本回收;加快完善需求侧响应电价机制以及虚拟电厂等聚合资源的商业模式,增加用户侧储能收益来源;加快完善电力市场建设,丰富各侧储能可参与的交易品种。

关键词：新型储能盈利模式新能源配储独立储能用户侧储能成本补偿机制

Ion transport regulation through triblock copolymer/PET asymmetric nanochannel membrane:Model system establishment and rectification mapping

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Chinese Chemical Letters 2021年第2期32卷 822-825页

作者： Linsen Yang Pei Liu congcong zhu Yuanyuan Zhao Miaomiao Yuan Xiang-Yu Kong Liping Wen Lei Jiang Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Future Technology University of Chinese Academy of ScienceBeijing 100049China The Eighth Affiliated Hospital Sun Yat-sen UniversityShenzhen 518033China

Controlling ions transport across the membrane at different pH environments is essential for the physiological process and artificial *** efforts have been devoted to pH-responsive ion gating,while rarely systems can maintain the rectification in pH-changing ***,a composite nanochannel system is fabricated,which shows unidirectional rectification with high performance in a wide pH *** the system,block copolymer(BCP) and polyethylene te rephthalate(PET) are employed for the amphoteric nanochannels *** on the composite system,a model is built for the theoretical ***,rectification mapping is conducted on the system,which can provide abundant info rmation about the relations between charge distribution and ions transport prope *** proposed rectification mapping can definitely help to design new materials with special ion transport properties,such as high-performance membranes used in the salinity gradient power generation field.

关键词： Nanochannel Unidirectional rectification Composited membrane Ion transport Rectification mapping