检索结果-南通市图书馆

Intermolecular coupling enhanced thermopower in single-molecule diketopyrrolopyrrole junctions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

national Science Open 2023年第1期2卷 13-23页

作者： Chao Fang Renad Almughathawi Qingqing Wu Wenqiang Cao Hang Chen Songjun Hou Yu Gu Hewei Zhang Yi Zhao Jueting Zheng Guopeng Li Jia Shi Junyang Liu Bing-Wei Mao Zitong Liu colin J.Lambert Wenjing Hong State Key Laboratory of physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Department of physics Lancaster UniversityLancaster LA14YBUK State Key Laboratory of Applied Organic Chemistry(SKLAOC) College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian province(IKKEM) Xiamen 361005China Beijing national Laboratory for Molecular Sciences Beijing 100190China Department of physics Faculty of ScienceTaibah UniversityMadinahSaudi Arabia

Sorting out organic molecules with high thermopower is essential for understanding molecular *** intermolecular coupling offers a unique chance to enhance the thermopower by tuning the bandgap structure of molecular devices,but the investigation of intermolecular coupling in bulk materials remains ***,we investigated the thermopower of diketopyrrolopyrrole(Dpp)cored single-molecule junctions with different coupling strengths by varying the packing density of the self-assembled monolayers(SAM)using a customized scanning tunneling microscope break junction(STM-BJ)*** found that the thermopower of Dpp molecules could be enhanced up to one order of magnitude with increasing packing density,suggesting that the thermopower increases with larger neighboring intermolecular *** combined density functional theory(DFT)calculations revealed that the closely-packed configuration brings stronger intermolecular coupling and then reduces the highest occupied molecular orbital(HOMO)-lowest unoccupied molecular orbital(LUMO)gap,leading to an enhanced *** findings offer a new strategy for developing organic thermoelectric devices with high thermopower.

关键词： single-molecule electronics single-molecule junctions thermopower thermoelectric devices intermolecular coupling

Interaction of Iron(III)-5,10,15,20-Tetrakis (4-Sulfonatophenyl) porphyrin with Chloroquine, Quinine and Quinidine

在线全文

学校读者我要写书评

暂无评论

Crystal Structure Theory and Applications 2017年第3期6卷 25-38页

作者： Dikima D. Bibelayi pitchouna I. Kilunga Albert S. Lundemba Matthieu K. Bokolo pius T. Mpiana philippe V. Tsalu Juliette pradon colin C. Groom Celine W. Kadima Luc Van Meervelt Zephyrin G. Yav Department of Chemistry University of Kinshasa Kinshasa Democratic Republic of Congo Department of Chemistry University of Ulsan Ulsan Republic of Korea The Cambridge Crystallographic Data Centre Cambridge UK Department of Chemistry State University of New York at Oswego Oswego USA Department of Chemistry Katholieke Universiteit Leuven Leuven Belgium

Iron(III)-5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrin (FeTppS) is used as non-physiological metalloporphyrin model for the natural iron (III)-protoporphyrin IX (FeppIX) resulting from hemoglobin degradation to investigate ligand binding reactions in aqueous solution. Studies were conducted on the interaction of FeTppS with Chloroquine, Quinine, and Quinidine, which are historically the most common quinoline-based drugs used to treat malaria, an infectious disease afflicting several hundred millions every year worldwide, mainly in tropical regions. Using UV-Visible spectrophotometry, the binding reaction was studied at pH 7.40 in purely aqueous solution, and in aqueous solution containing nanO3 at concentration of 0.1 M. Fitted titration curves obtained were in agreement with experimental data according to a formation scheme of 1:1 complex (1 FeTppS μ-oxo-dimer: 1 Antimalarial). Values of apparent binding constant (K) obtained were between 4.3 × 103 M-1 to 7.59 × 104 M-1, demonstrating that FeTppS and the antimalarials formed stable complexes. The stability of the complex decreased when nanO3 was added to the solution. This ionic strength dependence was ascribed to electrostatic effects. Quinine and Chloroquine interacted with FeTppS stronger than Quinidine did. Chloroquine showed the strongest affinity to FeTppS. These findings revealed the influence of steric and stereochemical factors. Molecular electrostatic potentials (MEp) calculated with Hartree-Fock theory argue in favor of π-π and electrostatic interactions between reaction partners as driving forces for the complex formation. In the case of FeTppS: Chloroquine interaction, it is suggested that an intramolecular hydrogen bond is formed between phenyl??and quinuclidine n-H+ as additional force stabilizing the complex. Analysis of crystallographic data using the Cambridge Structural Database (CSD) gave evidence of the hydrogen bond formation between phenyl??and n-H+ groups in 370 structures.

关键词： FeTppS Apparent Binding Constant (K) Molecular Electrostatic potential (MEp) Cambridge Structural Database (CSD)

petawatt and exawatt class lasers worldwide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High power Laser Science and Engineering 2019年第3期7卷 168-221页

作者： colin n.Danson Constantin Haefner Jake Bromage Thomas Butcher Jean-Christophe FChanteloup Enam A.Chowdhury Almantas Galvanauskas Leonida A.Gizzi Joachim Hein David I.Hillier nicholas W.Hopps Yoshiaki Kato Efim A.Khazanov Ryosuke Kodama Georg Korn Ruxin Li Yutong Li Jens Limpert Jingui Ma Chang Hee nam David neely Dimitrios papadopoulos Rory R.penman Liejia Qian Jorge J.Rocca andrey A.Shaykin Craig W.Siders Christopher Spindloe Sándor Szatmári Raoul M.G.M.Trines Jianqiang Zhu ping Zhu Jonathan D.Zuegel AWE AldermastonReadingUK OxCHEDS Clarendon LaboratoryDepartment of PhysicsUniversity of OxfordOxfordUK CIFS Blackett LaboratoryImperial CollegeLondonUK nIF&photon Science Directorate Lawrence Livermore National LaboratoryLivermoreUSA Fraunhofer Institute for Laser Technology(ILT) AachenGermany Chair for Laser Technology LLT RWTH Aachen UniversityAachenGermany University of Rochester Laboratory for Laser EnergeticsRochesterUSA Central Laser Facility STFC Rutherford Appleton LaboratoryChiltonDidcotUK LULI CNRSCEASorbonne UniversitesEcole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance Department of physics The Ohio State UniversityColumbusUSA Centre for Ultrafast Optical Science University of MichiganAnn ArborUSA Intense Laser Irradiation Laboratory Istituto Nazionale di Ottica(INO)CNRPisaItaly Institute of Optics and Quantum Electronics Friedrich-Schiller-University Jena and Helmholtz InstituteJenaGermany The Graduate School for the Creation of new photonics Industries NishikuHamamatsuJapan Institute of Applied physics Russian Academy of SciencesNizhny NovgorodRussia Institute of Laser Engineering Osaka UniversitySuitaOsakaJapan ELI-Beamlines Institute of PhysicsCzech Academy of SciencesPragueCzech Republic State Key Laboratory of High Field Laser physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China national Laboratory for Condensed Matter physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Institute for Applied physics(IAp)at Friedrich-Schiller-University Jena JenaGermany Helmholtz Institute Jena JenaGermany Fraunhofer Institute for Applied Optics and precision Engineering(IOF) JenaGermany Key Laboratory for Laser plasma(Ministry of Education) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Centre for Relativistic Laser Science(CoReLS) Institute for Basic ScienceDepartment of Physics and Photon ScienceGwangju Institute of Science and Techno

In the 2015 review paper‘petawatt Class Lasers Worldwide’a comprehensive overview of the current status of highpower facilities of>200 TW was *** was largely based on facility specifications,with some description of their uses,for instance in fundamental ultra-high-intensity interactions,secondary source generation,and inertial confinement fusion(ICF).With the 2018 nobel prize in physics being awarded to professors Donna Strickland and Gerard Mourou for the development of the technique of chirped pulse amplification(CpA),which made these lasers possible,we celebrate by providing a comprehensive update of the current status of ultra-high-power lasers and demonstrate how the technology has *** are now in the era of multi-petawatt facilities coming online,with 100 pW lasers being proposed and even under *** addition to this there is a pull towards development of industrial and multi-disciplinary applications,which demands much higher repetition rates,delivering high-average powers with higher efficiencies and the use of alternative wavelengths:mid-IR *** apart from a comprehensive update of the current global status,we want to look at what technologies are to be deployed to get to these new regimes,and some of the critical issues facing their development.

关键词： exawatt lasers high-power lasers petawatt lasers ultra-high intensity

Microalgae Cultivation Using Offshore Membrane Enclosures for Growing Algae (OMEGA)

在线全文

学校读者我要写书评

暂无评论

Journal of Sustainable Bioenergy Systems 2013年第1期3卷 18-32页

作者： patrick Wiley Linden Harris Sigrid Reinsch Sasha Tozzi Tsegereda Embaye Kit Clark Brandi McKuin Zbigniew Kolber Russel Adams Hiromi Kagawa Tra-My Justine Richardson John Malinowski colin Beal Matthew A. Claxton Emil Geiger Jon Rask J. Elliot Campbell Jonathan D. Trent Advanced Organic Methods Penryn USA Department of Chemistry University of California Santa Cruz USA Department of Mechanical Engineering University of Nevada Reno USA Department of Ocean Sciences University of California Santa Cruz USA Dynamac Corporation NASA Ames Research Center Moffett Field USA nASA Ames Research Center Moffett Field USA School of Engineering University of California Merced USA SETI Institute Mountain View USA Universities Space Research Association Columbia USA

OMEGA is a system for cultivating microalgae using wastewater contained in floating photobioreactors (pBRs) deployed in marine environments and thereby eliminating competition with agriculture for water, fertilizer, and land. The offshore placement in protected bays near coastal cities co-locates OMEGA with wastewater outfalls and sources of CO2-rich flue gas on shore. To evaluate the feasibility of OMEGA, microalgae were grown on secondary-treated wastewater supplemented with simulated flue gas (8.5% CO2 V/V) in a 110-liter prototype system tested using a seawater tank. The flow-through system consisted of tubular pBRs made of transparent linear low-density polyethylene, a gas exchange and harvesting column (GEHC), two pumps, and an instrumentation and control (I&C) system. The pBRs contained regularly spaced swirl vanes to create helical flow and mixing for the circulating culture. About 5% of the culture volume was continuously diverted through the GEHC to manage dissolved oxygen concentrations, provide supplemental CO2, harvest microalgae from a settling chamber, and add fresh wastewater to replenish nutrients. The I&C system controlled CO2 injection and recorded dissolved oxygen levels, totalized CO2 flow, temperature, circulation rates, photosynthetic active radiation (pAR), and the photosynthetic efficiency as determined by fast repetition rate fluorometry. In two experimental trials, totaling 23 days in April and May 2012, microalgae productivity averaged 14.1 ± 1.3 grams of dry biomass per square meter of pBR surface area per day (n = 16), supplemental CO2 was converted to biomass with >50% efficiency, and >90% of the ammonia-nitrogen was recovered from secondary effluent. If OMEGA can be optimized for energy efficiency and scaled up economically, it has the potential to contribute significantly to biofuels production and wastewater treatment.

关键词： Biofuels Wastewater Treatment Microalgae photobioreactor CO2 Mass Transfer Fast Repetition Rate Fluorometry Instrumentation and Control

主题建模辅助哲学研究的方法论探究——以《论语》《孟子》《荀子》的计算分析为例

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

数字人文研究 2021年第2期1卷 36-50页

作者：高元昊王小红科林·艾伦杨钊西安交通大学人文社会科学学院匹兹堡大学科学哲学科学史系西安交通大学计算机科学与技术学院

近年来被广泛运用于史学、文学研究的LDA主题建模不仅仅可以用于发现庞大语料库的整体意义结构,将LDA运用于哲学语料库,再聚焦于具体文本,还可以揭示小文本意义特征和文本间意义关系,从而进行哲学发现,并为一些哲学命题提供实证论据.作... 详细信息

近年来被广泛运用于史学、文学研究的LDA主题建模不仅仅可以用于发现庞大语料库的整体意义结构,将LDA运用于哲学语料库,再聚焦于具体文本,还可以揭示小文本意义特征和文本间意义关系,从而进行哲学发现,并为一些哲学命题提供实证论据.作为一种新方法,LDA的有效性与客观性需要被检验.首先,基于新汉典语料库,以《论语》《孟子》《荀子》的LDA建模研究为例,展示该研究从建模到得出推论的全过程.其次,将模型数据和哲学推论与Sn关于上述三部典籍的数字人文研究进行对比,分析不同推论的原因,论述运用LDA发现小文本的意义特征和文本间关系的有效性.最后,使用控制变量法对Ctext语料库进行建模,对比不同参数下模型所呈现的《论语》主题分布,论述该方法的客观性条件仅与k值设置有关,当k取值于收敛向"理想状态"的一段区间时,LDA能最大程度避免主观性因素的干扰,保证该研究方法的客观性.

关键词： LDA主题建模计算哲学研究数字人文《论语》《孟子》《荀子》

Identification of new genetic risk factors for prostate cancer

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2009年第1期11卷 49-55页

作者： Michelle Guy Zsofia Kote-Jarai Graham G. Giles Ali Amin Al Olama Sarah K. Jugurnauth Shani Mulholland Daniel A. Leongamomlert Stephen M. Edwards Jonathan Morrison Helen I. Field Melissa C. Southey Gianluca Severi Jenny L. Donovan Freddie C. Hamdy David R Dearnaley Kenneth R. Muir Charmaine Smith Melisa Bagnato Audrey T. Ardern-Jones Amanda L. Hall Lynne T. O＇Brien Beatrice n. Gehr-Swain Rosemary A. Wilkinson Angela Cox Sarah Lewis paul M. Brown Sameer G. Jhavar Malgorzata Tymrakiewicz Artitaya Lophatananon Sarah L. Bryant The UK Genetic prostate Cancer Study Collaborators British Association of Urological Surgeons＇ Section of Oncology and The UK protecT Study Collaborators Alan Horwich Robert A. Huddart Vincent S. Khoo Christopher C. parker Christopher J. Woodhouse Alan Thompson Tim Christmas Chris Ogden Cyril Fisher Charles Jameson colin S. Cooper Dallas R. English John L. Hopper David E. neal Douglas E Easton Rosalind A. Eeles Section of Cancer Genetics The Institute of Cancer Research Sutton Surrey SM2 5NG UK Cancer Epidemiology Centre The Cancer Council Victoria Carlton VIC 3053 Australia Centre for Molecular Environmental Genetic and Analytic Epidemiology The University of Melbourne Carlton VIC 3053 Australia Cancer Research UK Genetic Epidemiology Unit University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Department of Oncology University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Genetic Epidemiology Laboratory Department of Pathology The University of Melbourne Parkville VIC 3052 Australia Department of Social Medicine University of Bristol Bristol BS8 2PR UK Academic Urology Unit University of Sheffield Sheffield SIO 2JF UK The Royal Marsden nHS Foundation Trust Sutton Surrey SM2 5PT and London SW3 6JJ UK University of nottingham Medical School Queens Medical Centre Nottingham NG7 2UH UK Institute for Cancer Studies University of Sheffield Sheffield SIO 2RX UK Surgical Oncology （Uro-Oncology S4） Departments of Oncology and Surgery University of Cambridge Addenbrooke＇s Hospital Cambridge CB2 2QQ UK A full list of authors is provided in the Supplementary note online Ka Shing Centre Cambridge CB2 ORE UK Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Cambridge CB2 ORE UK.

There is evidence that a substantial part of genetic predisposition to prostate cancer （pCa） may be due to lower penetrance genes which are found by genome-wide association studies. We have recently conducted such a study and seven new regions of the genome linked to pCa risk have been identified. Three of these loci contain candidate susceptibility genes： MSMB, LMTK2 and KLK2/3. The MSMB and KLK2/3 genes may be useful for pCa screening, and the LMTK2 gene might provide a potential therapeutic target. Together with results from other groups, there are now 23 germline genetic variants which have been reported. These results have the potential to be developed into a genetic test. However, we consider that marketing of tests to the public is premature, as pCa risk can not be evaluated fully at this stage and the appropriate screening protocols need to be developed. Follow-up validation studies, as well as studies to explore the psychological implications of genetic profile testing, will be vital prior to roll out into healthcare.

关键词： prostate cancer genetics susceptibility loci Snps relative risks

2％哌仑西平眼胶用于近视儿童的安全性与有效性——一项为期一年的多中心双盲并设有安慰剂对照的平行研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

美国医学会眼科杂志（中文版） 2005年第4期17卷 195-201页

作者： R. Michael Siatkowski Susan Cotter Joseph M. Miller colin A. Scher R. Stephens Crockett Gary D. novack 乔荣华（译）王为群（译）任泽钦（校） the US pirenzepine Study Group 不详

目的：评估相对选择性M1受体拮抗剂盐酸哌仑西平对延缓学龄儿童近视进展的安全性与有效性。方法：本研究在8～12岁的健康儿童中进行。平行分组，设安慰剂对照并采用双盲法。受试者的等效球镜度数为-0．75～-4．00屈光度（D），散光度数... 详细信息

目的：评估相对选择性M1受体拮抗剂盐酸哌仑西平对延缓学龄儿童近视进展的安全性与有效性。方法：本研究在8～12岁的健康儿童中进行。平行分组，设安慰剂对照并采用双盲法。受试者的等效球镜度数为-0．75～-4．00屈光度（D），散光度数小于或等于1．00D。患者受试之前都接受过全面的眼科检查作为基线标准并在1年的时间内定期检查。共有13家美国的医疗机构和私人诊所参与。患者按2：1的比例随机分组，分别给予2％哌仑西平眼胶或安慰剂对照，每日两次，历时1年。结果：在刚纳入研究时，哌仑西平组的等效球镜度数为-2．098±0．903D（均值±标准差，n=117），安慰剂组为-1．933±0．825D（n=57，p=0．22）。1年后哌仑西平组的近视程度平均增加了0．26D而安慰剂组则增加了0．53D（p〈0．001）。安慰剂组无人中途退出，哌仑西平组的117人中却有13名（11％）因为不良反应而终止试验[117人中的5人（4％）是由于过度的抗毒蕈碱反应]。结论：在为期1年的治疗中哌仑西平对延缓近视进展有效并相对安全。

关键词：安慰剂对照哌仑西平近视进展学龄儿童安全性中心双盲平行等效球镜度数 M1受体拮抗剂不良反应

preserving cognitive function in patients with Alzheimer's disease:The Alzheimer's disease neuroprotection research initiative(ADnRI)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

neuroprotection 2023年第2期1卷 84-98页

作者： Jie Liu Heleen van Beusekom Xian-Le Bu Gong Chen paulo Henrique Rosado de Castro Xiaochun Chen Xiaowei Chen Andrew n.Clarkson Tracy D.Farr Yuhong Fu Jianping Jia Jukka Jolkkonen Woojin Scott Kim paula Korhonen Shen Li Yajie Liang Guang-Hui Liu Guiyou Liu Yu-Hui Liu Tarja Malm Xiaobo Mao Joaquim Miguel Oliveira Mike M.Modo pedro Ramos-Cabrer Karsten Ruscher Weihong Song Jun Wang Xuanyue Wang Yun Wang Haitao Wu Lize Xiong Yi Yang Keqiang Ye Jin-Tai Yu Xin-Fu Zhou Marietta Zille colin L.Masters piotr Walczak Boltze Johannes Xunming Ji Yan-Jiang Wang Department of neurology Daping HospitalThird Military Medical UniversityChongqingChina Chongqing Key Laboratory of Ageing and Brain Diseases ChongqingChina Division of Experimental Cardiology Department of CardiologyErasmus MCUniversity Medical CenterRotterdamThe Netherlands Institute of Brain and Intelligence Third Military Medical UniversityChongqingChina Guangdong-HongKong-Macao Institute of CnS Regeneration(GHMICR) Jinan UniversityGuangzhouGuangdongChina Institute of Biomedical Sciences Federal University of Rio de JaneiroRio de JaneiroRio de JaneiroBrazil Fujian Key Laboratory of Molecular neurology Department of Neurology and GeriatricsFujian Institute of GeriatricsFujian Medical University Union HospitalInstitute of NeuroscienceFujian Medical UniversityFuzhouFujianChina Guangyang Bay Laboratory Chongqing Institute for Brain and IntelligenceChongqingChina Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghaiChina Department of Anatomy Brain Health Research Centre and Brain Research New ZealandUniversity of OtagoDunedinNew Zealand School of Life Sciences University of NottinghamNottinghamUK Brain and Mind Centre&School of Medical Sciences The University of SydneySydneyNew South WalesAustralia Innovation Center for neurological Disorders and Department of neurology Xuanwu HospitalNational Clinical Research Center for Geriatric DiseasesCapital Medical UniversityBeijingChina A.I.Virtanen Institute for Molecular Sciences University of Eastern FinlandKuopioFinland Department of neurology and psychiatry Beijing Shijitan HospitalCapital Medical UniversityBeijingChina Department of Diagnostic Radiology and nuclear Medicine University of Maryland School of MedicineBaltimoreMarylandUSA University of Chinese Academy of Sciences BeijingChina State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Sci

The global trend toward aging populations has resulted in an increase in the occurrence of Alzheimer's disease(AD)and associated socioeconomic *** metabolism of amyloid-β(Aβ)has been proposed as a significant pathomechanism in AD,supported by results of recent clinical trials using anti-Aβ***,the cognitive benefits of the current treatments are *** etiology of AD is multifactorial,encompassing Aβand tau accumulation,neuroinflammation,demyelination,vascular dysfunction,and comorbidities,which collectively lead to widespread neurodegeneration in the brain and cognitive ***,solely removing Aβfrom the brain may be insufficient to combat neurodegeneration and preserve *** attain effective treatment for AD,it is necessary to(1)conduct extensive research on various mechanisms that cause neurodegeneration,including advances in neuroimaging techniques for earlier detection and a more precise characterization of molecular events at scales ranging from cellular to the full system level;(2)identify neuroprotective intervention targets against different neurodegeneration mechanisms;and(3)discover novel and optimal combinations of neuroprotective intervention strategies to maintain cognitive function in AD *** Alzheimer's Disease neuroprotection Research Initiative's objective is to facilitate coordinated,multidisciplinary efforts to develop systemic neuroprotective strategies to combat *** aim is to achieve mitigation of the full spectrum of pathological processes underlying AD,with the goal of halting or even reversing cognitive decline.

关键词： Alzheimer's disease early intervention neural regeneration neuroprotection systematic perspective

多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国呼吸与危重监护杂志 2021年第2期20卷 77-84页

作者：王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki noble Laurent Zieleskiewicz pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano peiman nazerian Bret p.nelson Aleksandar n.neskovic Ramon nogue Adi Osman Josépazeli Elmo pereira-Junior Tomislav petrovic Emanuele pivetta Jan poelaert Susanna price Gregor prosen Shalim Rodriguez philippe Rola colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi 中国人民解放军空军军医大学航空航天医学系陕西西安710032 Department of Cardiac Sciences King Abdulaziz Medical City and King Abdullah International Medical Research Center 不详

新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征... 详细信息

新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。

关键词：体征和症状肺炎公共卫生体系呼吸系统首次报道专家共识疫情