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Physico-chemical characterization of acid base disorders in patients with COVID-19:A cohort study

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World Journal of Nephrology 2024年第2期13卷 16-23页

作者： Sergio Pinto de Souza Juliana r Caldas Marcelo Barreto Lopes Marcelo Augusto Duarte Silveira Fernanda Oliveira coelho Igor Oliveira Queiroz Pedro Domingues Cury rogério da Hora Passos Department of Nephrology Hospital São RafaelSalvadorBA 41253190Brazil Department of Nephrology D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Faculty of Medicine Escola Bahiana de Medicina e Saúde Pública-EBMSPSalvadorBA 40290000Brazil Department of Intensive Care D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Hospital São rafael D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Department of Intensive Care Unit Hospital Israelita Albert EinsteinSao PauloSP 05652900Brazil

BACKgrOUND Acid-base imbalance has been poorly described in patients with coronavirus disease 2019(COVID-19).Study by the quantitative acid-base approach may be able to account for minor changes in ion distribution that may have been over-looked using traditional acid-base analysis *** a cohort of critically ill COVID-19 patients,we looked for an association between metabolic acidosis surrogates and worse clinical outcomes,such as mortality,renal dialysis,and length of hospital *** To describe the acid-base disorders of critically ill COVID-19 patients using Stewart’s approach,associating its variables with poor *** This study pertained to a retrospective cohort comprised of adult patients who experienced an intensive care unit stay exceeding 4 days and who were diagnosed with severe acute respiratory syndrome coronavirus 2 infection through a positive polymerase chain reaction analysis of a nasal swab and typical pulmonary involvement observed in chest computed tomography *** and clinical data were obtained from electronic *** variables were compared using Fisher’s exact *** data were presented as median and interquartile *** Mann-Whitney U test was used for *** In total,211 patients were *** mortality rate was 13.7%.Overall,149 patients(70.6%)presented with alkalosis,28 patients(13.3%)had acidosis,and the remaining 34 patients(16.2%)had a normal arterial pondus *** those presenting with acidosis,most had a low apparent strong ion difference(SID)(20 patients,9.5%).Within the group with alkalosis,128 patients(61.0%)had respiratory *** non-survivors were older,had more comorbidities,and had higher Charlson’s and simplified acute physiology score *** did not find severe acid-base imbalance in this *** analyzed Stewart’s variables(effective SID,apparent SID,and strong ion gap and the effect of albumin,lactate,phosphorus,and chloride)were not d

关键词： COVID-19 Physicochemical approach Acid-base status Critically ill patients Acute respiratory syndrome

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葡萄牙山火危机

财新周刊 2024年第38期 12-13页

作者： Jose coelho(图) 东方IC

当地时间2024年9月17日,葡萄牙北部,民众因山火持续肆虐紧急撤离。截至当地时间9月18日7时,该国仍有114起火灾处在活跃状态,超过5000名消防人员和1600辆消防车辆投入灭火工作,当地政府连夜疏散火场附近居民,部分高速路段被迫关闭。葡萄... 详细信息

当地时间2024年9月17日,葡萄牙北部,民众因山火持续肆虐紧急撤离。截至当地时间9月18日7时,该国仍有114起火灾处在活跃状态,超过5000名消防人员和1600辆消防车辆投入灭火工作,当地政府连夜疏散火场附近居民,部分高速路段被迫关闭。葡萄牙海洋与大气研究所的消息显示,由于天气炎热,该国9个大区的超过50个市镇面临火灾风险。截至18日,葡萄牙本轮火灾已造成7人死亡。据统计葡萄牙波尔图市以南地区的山林火灾已经烧毁1.5572万公顷土地。此前,葡萄牙政府部门呼吁欧盟国家派遣消防队增援,西班牙、意大利和希腊已提供了支援。

关键词：消防人员灭火工作消防车辆火灾风险山火消防队葡萄牙活跃状态

risk Stratification in Obstetrics: An Integrated Approach to Maternal Health

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Open Journal of Obstetrics and gynecology 2024年第6期14卷 903-910页

作者： Taina Crespo Mendonca Bianca Beatriz Soares dos reis Júlia Cruz coelho Antônio de Oliveira Battistini Pestana Vitória Carolina Barreto Negri Alvaro Augusto Trigo Department of Medicine University of Franca Franca Brazil

Introduction: Prenatal care is crucial for maternal and fetal health, highlighting the importance of obstetric risk stratification. This enables personalized care, avoiding unnecessary interventions and reducing costs. Conditions such as first trimester bleeding, spontaneous abortion, gestational trophoblastic disease, and ectopic pregnancy require specific approaches. Early identification of these complications is vital, especially in urgent and emergency obstetric cases, which demand immediate hospital attention. Objective: Comprehensive review of first trimester pathologies and gestational hypertension, focusing on obstetric risks and personalized prenatal management. Methods: Literature review on bleeding and gestational hypertension. results: The study provides a detailed analysis of pathologies associated with first trimester uterine bleeding and hypertensive disorders, focusing on obstetric risk stratification. The main causes of maternal and fetal mortality are hypertensive disorders, hemorrhages, infections, childbirth complications, and abortion. Spontaneous abortion is common, with different classifications, ranging from threatened to missed abortion. Infected abortion is a severe complication. Brazil has restrictive abortion laws, but many unsafe abortions occur, resulting in high public health costs. Pharmacological treatment with misoprostol is a safe option. Other pathologies include gestational trophoblastic disease, ectopic pregnancy, and placenta previa. Preeclampsia and eclampsia are severe conditions requiring immediate treatment to avoid complications. Conclusion: Early identification and management of obstetric risk factors, such as uterine bleeding, are essential for positive maternal and fetal outcomes. A multidisciplinary approach is fundamental.

关键词： Obstetrics Emergencies Hypertension Pregnancy-Induced Uterine Hemorrhage Pregnancy Trimester First

Marigold(Tagetes erecta): The Potential Value in the Phytoremediation of Chromium

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Pedosphere 2017年第3期27卷 559-568页

作者： Lívia C.coelho Ana rosa r.BASTOS Paulo J.PINHO guilherme A.SOUZA Janice g.CArVALHO Viviane A.T.coelho Luiz Carlos A.OLIVEIrA rimena r.DOMINgUES Valdemar FAQUIN Soil Science Department Federal University of Lavras Chemistry Department Federal University of Minas Gerais

Environmental pollution with chromium （Cr） is harmful to humans, animals and plants, while in plants it causes diminished growth, anatomical alterations and death. In the present study, the potential value of marigold （Tagetes erecta） in the phytoremediation of Cr has been investigated. The randomized experimental design involved the exposure of plants to nutrient solutions containing 0.00, 0.04, 0.08, 0.12, 0.16 or 0.24 mmol L-1 Cr（III）. Chromium toxicity was observed at Cr（III） concentrations ≥ 0.12 mmol L-1 as demonstrated by diminished growth of the aerial parts and reduced density of the root system. Increasing Cr（III） concentrations in the nutrient solution resulted in a higher bioaccumulation of total Cr in the tissues, although translocation from roots to aerial parts was not efficient （maximum value of 25% at 0.12 mmol L-1 Cr（III））. The Cr bioaccumulation was up to 11-fold greater in roots than in the aerial parts. Tagetes erecta exhibited leaf plasticity when exposed to Cr, indicating the existence of a tolerance mechanism to Cr in this species. Chromium caused a reduction in xilem vases, resulting in a plastic effect in T. erecta leaves that increased the metal tolerance in culture solution. Tagetes spp. are potential Cr hyperaccumulators; at Cr（III） concentrations up to 0.12 mmol L-1, the plants accumulated levels above that proposed for hyperaccumulators and still maintained a considerable growth and even flourished. However, this study was conducted in nutrient solution, and studies on species confirmation as Cr hyperaccumulator should be conducted in soils for further clarification.

关键词： anatomical alterations heavy metal hyperaccumulor leaf anatomy toxicity

Sintering effects on chemical and physical properties of bioactive ceramics

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Journal of Advanced Ceramics 2013年第3期2卷 274-284页

作者： Lukasz WITEK James SMAY Nelson r.F.A.SILVA Teja gUDA Joo L.ONg Paulo g.coelho School of Chemical Engineering Oklahoma State University423 Engineering NorthStillwaterOKUSA Department of Biomaterials and Biomimetics New York University345 East 24th Street804S New YorkNYUSA Department of Operative Dentistry Universidade Federal de Minas GeraisPampulhaBelo HorizonteMGBrazil Department of Biomedical Engineering University of Texas San AntonioOne UTSA CircleSan AntonioTXUSA Department of Periodontology and Implant Dentistry College of DentistryNew York University345 East 24th StreetNew YorkNYUSA

The objective of this study was to characterize the chemical and physical properties of bioactive ceramics prepared from an aqueous paste containing hydroxyapatite(HA)and beta tri-calcium phosphate(β-TCP).Prior to formulating the paste,HA andβ-TCP were calcined at 800℃and 975℃(11 h),milled,and blended into 15%/85%HA/β-TCP volume-mixed *** cylindrical rods were subsequently sintered to 900℃,1100℃or 1250℃.The sintered specimens were characterized by helium pycnometry,X-ray diffraction(XrD),Fourier transform-infrared(FT-Ir),and inductively coupled plasma(ICP)spectroscopy for evaluation of porosity,crystalline phase,functional-groups,and Ca:P ratio,*** properties were assessed via 3-point bending and diametral *** microstructural evaluation using scanning electron microscopy(SEM)showed larger pores and a broader pore size distribution(PSD)for materials sintered at 900℃and 1100℃,whereas the 1250℃samples showed more uniform *** quantification showed significantly higher porosity for materials sintered to 900℃and 1250℃(prD indicated substantial deviations from the 15%/85%HA/β-TCP formulation following sintering where lower amounts of HA were observed when sintering temperature was *** testing demonstrated significant differences between calcination temperatures and different sintering regimes(priation in chemical composition and mechanical properties of bioactive ceramics were direct consequences of calcination and sintering.

关键词： bone graft material chemical/physical characterization sintering bi-phasic calcium phosphate(BCP)

Effect of Soybean Cultivars on the Nutrients and Consumer Acceptance of Soymilk

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Food and Nutrition Sciences 2024年第8期15卷 807-826页

作者： Ilana Felberg Mercedes Concórdia Carrão-Panizzi rosires Deliza Sidinéa Cordeiro de Freitas Manuela Cristina Pessanha de Araujo Santiago Marilia Penteado Stephan Monalisa Santana coelho de Jesus Elisabeth Borges gonçalves rosemar Antoniassi Embrapa Food Technology Rio de Janeiro Brazil Embrapa Wheat Passo Fundo Brazil

Soymilk is one of the most available beverages, an alternative to dairy milk and is recognized for its nutritional value. The nutritional quality, the presence of anti-nutritional factors, isoflavones and sensory acceptability of soymilk depended on the soybean variety as well as the processing conditions. The soymilks from conventional and specialty Brazilian soybean cultivars were compared regarding the composition and consumer acceptance. There were significant differences on the protein, oil, sugars, isoflavones, presence of anti-nutritional factors (phytate and trypsin inhibitor activity) and NSI (nitrogen solubility index) among cultivars and soymilks and for sensory acceptance of soymilks. The preference mapping and cluster analysis identified three different segments of consumers. The soymilk from the conventional cultivar BrS284 achieved higher and similar acceptance score for the three consumer’s segments while the lipoxygenase free cultivars (BrS213 and BrS257) and specialty cultivar BrS216 showed higher score for two segments of consumers. The sensory evaluation of soymilk from different soybean cultivars could improve consumer uptake.

关键词： Preference Mapping Cluster Analysis Protein Phytate

Poroelastic solid flow with double point material point method

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Journal of Hydrodynamics 2017年第3期29卷 423-430页

作者： Bruno Zuada coelho Alexander rohe Kenichi Soga Department of geo-engineering DeltaresDelftrife-Netherlands Department of Engineering University of CambridgeCambridgeUK

This paper presents the numerical modelling of one and two-dimensional poroelastic solid flows,using the material point method with double point *** double point formulation offers the convenience of allowing for transitions in the flow conditions of the liquid,between free surface flow and groundwater *** numerical model is validated by comparing the solid flow velocity with the analytical *** influence of the Young＇s modulus on the solid flow velocity is discussed for both one and two-dimensional analysis *** effect of the shape of the two-dimensional solid is *** is shown that the solid stiffness has an effect on the poroelastic flow velocity,due to swelling and bending for the one and two-dimensional cases,*** shape is found to be an important factor on the flow velocity of the poroelastic solid.

关键词： Material point method geocontainers double point formulation large deformations

Critical analysis of molluscicide application in schistosomiasis control programs in Brazil

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Infectious Diseases of Poverty 2016年第1期5卷 485-490页

作者： PMZ coelho rL Caldeira research group of Schistosoma mansoni Biology and Its Interaction with the Host RenéRachou InstituteOswaldo Cruz Foundation-Minas Gerais30190-002 Belo HorizonteMGBrazil research group of Medical Helminthology and Malacology RenéRachou InstituteOswaldo Cruz Foundation-Minas Gerais30190-002 Belo HorizonteMGBrazil

In Brazil,Biomphalaria glabrata,***,and *** are naturally infected by the trematode Schistosoma mansoni,the causative agent of *** decades of governmental efforts through official control programs,schistosomiasis remains an important public health problem in the country:thousands of people are infected with the trematode each year and millions live in endemic *** World Health Organization recommends using a combination of molluscicide(niclosamide)and mass chemotherapy to control the transmission of schistosomiasis,with this treatment successfully reducing the morbidity of the *** the past,niclosamide has been used in official schistosomiasis control programs in ***,as *** recolonizes even after molluscicide application,the use of molluscicides has gradually decreased in the country until they were discontinued in 2002,mainly due to the rising global pressure to preserve the environment and the difficulties of obtaining licenses from the Brazilian Ministry of Environment to use toxic substances in aquatic ***,the discovery of new molluscicides,which could be more selective to Biomphalaria species and less harmful to the aquatic ecosystem,is *** addition,political efforts to sensitize funders to provide grants for this field of research are *** this context,this article aims to make a critical analysis of molluscicide application in schistosomiasis control programs in Brazil.

关键词： Biomphalaria Molluscicide Schistosoma mansoni Schistosomiasis Vector control Braz

Boll weevils in dry bolls:is there a performance disadvantage?

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Journal of Cotton research 2024年第3期7卷 243-252页

作者： coelho Beatriz S. LEITE Suzany A. SANTOS Mateus P.dos MATES Eloito C.de MOrAES Beatriz M.L.de BASTOS Cristina S. gUEDES raul N.C. MOrEIrA Aldenise A. CASTELLANI Maria A. Departamento de Fitotecnia e Zootecnia Universidade Estadual do Sudoeste da BahiaVitória da ConquistaBA 45031‑900Brazil Faculdade de Agronomia e Veterinária Universidade de BrasíliaBrasíliaDF 70910‑900Brazil Departamento de Entomologia Universidade Federal de ViçosaViçosaMG 36570‑900Brazil Pós‑graduaCão em Agronomia(Fitotecnia) Universidade Estadual do Sudoeste da BahiaVitória da ConquistaBA 45031‑900Brazil

Background Anthonomus grandis grandis is the main cotton pest in the Americas,with the potential to become a pest in other *** insect uses the plant's reproductive organs for feeding,oviposition,and survival strategies in the off-season,sheltering in dry *** study aimed to know the reproductive potential,feeding,longevity,and morphometric characteristics of boll weevils from dry bolls,squares,and *** were obtained from infested squares,dry bolls,and traps installed in cotton fields and the Caatinga *** weevil pairs were maintained in the laboratory to assess the oviposition,feeding holes,longevity,and morphometric measurements of the parental and F_(1) *** In the parental generation,boll weevils from traps(the Caatinga area and cotton cultivation)showed greater reproductive *** weevils from squares and the Caatinga area showed greater feeding activity compared with those from cotton *** rostrum length,thorax+abdomen length,and abdomen width were observed in boll weevils from cotton cultivation and dry *** origin of boll weevils parental generation did not affect progeny emergence *** F_(1) generation of boll weevils showed significant differences in average longevity depending on the origin of different ***,differences in rostrum lengths were observed,with the boll weevils coming from traps installed in cotton cultivation,the Caatinga area,and dry bolls being the *** thorax+abdomen length and abdomen width,the highest values were observed in those from the Caatinga area and cotton *** It was proven that dry bolls did not affect the reproductive,feeding,and longevity performance of boll weevils,enabling better insect fitness(reproduction and size)in relation to those coming from *** use of dry bolls as off-season shelter is an important survival strategy for the boll weevil.

关键词： Anthonomus grandis grandis gossypium hirsutum Off-season Survival