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Petroleum Science 2018年第2期15卷 421-431页

作者： claudio benevenuto de campos lima Pedro Esteves Aranha Jose Francisco Tebaldi de Castro Gilson Brito Alves lima Augusto Borella Hougaz Felipe de Souza Terra Petrobras department of Production Engineering Federal Fluminense University

In order to avoid mistakes and to save a great deal of time in analysis, an innovative methodology was developed that can analyze the well operations and rig characteristics involved to define the best emergency disconnect sequence （EDS） available. A solution was developed based on the characteristics of the rigs and blowout preventers （BOPs）, and six variables were considered that directly affect the choice of EDS. All possible combinations of 64 scenarios were analyzed, and the priority of choice of the EDS was defined empirically. This paper presents an approach to EDS risk management and examples of exposure time （time without riser safety margin and shear capability） for the same well, which can be lowered from 13% to 0.1%. The impact of this reduction is related to the ability of the BOP to cut some of the heavy casings, in addition to improved availability of EDS modes. This implementation opened up many possibilities for the performance of risk exposure analysis, enabling comparison of several BOP configurations of contracted rigs and selection of the best options. This innovative approach allowed a better management of the rig schedules, prioritizing safety aspects and making it possible to allocate the fleet in a systematic way.

关键词： Well safety Safety barriers Emergency disconnect sequence (EDS) Well control Kick Well design

Mayaro fever:A brief review on the immune profile

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Asian Pacific Journal of Tropical Biomedicine 2020年第3期10卷 95-100页

作者： Jean Moisés Ferreira Danielly Santos campos-Ferreira Elaine Virgínia Martins de Sousa Figueiredo Jose Luizde lima Filho Laboratório de Imunopatologia Keizo Asami-LIKA Centro de BiociênciasUniversidade Federal de Pernambuco(UFPE)50670-901RecifePernambucoBrazil Laboratório de Biologia Molecular e Expressao Genica-LABMEG Departamento de Ciências BiológicasUniversidade Federal de Alagoas(UFAL)Campus Arapiraca57300-970ArapiracaAlagoasBrazil

Mayaro virus is an emergent alphavirus that infects humans,leading to Mayaro *** fifty percent of infected patients develop arthritis symptoms in the recovery phase,a phase that can last up to a *** literature about Mayaro virus infection and its immune response is scarce,which may hamper the development of treatment *** summarize changes in cytokines and chemokines in the acute and recovery phase in Mayaro virus infected patients,and relate this molecular characterization with the immune *** and IL-12/p70 show pronounced changes in patients in the acute phase,suggesting the development of cellular immunity and Th1 ***-6,IL-7,CXCL8/IL-8,IL-13,IL-17,and IFN-γare elevated in patients with arthritis symptoms in the long-term recovery phase,which may be related to the continuous inflammatory process,a possible Th2 inhibiting and promoting Th17 *** few studies discuss the issue,with a small number of patients and different backgrounds,inflammatory and immune response and manifestations seem to be closely *** information may help to develop the appropriate treatment strategies in Mayaro virus ***,we analyzed and summarized data available in literature.

关键词： Emergent virus Mayaro virus Cytokines Chemokine Molecular characterization

Anthropological examination in burned body:a retrospective identification case

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Forensic Sciences Research 2022年第4期7卷 633-636页

作者： Marcos Paulo Salles Machado Andrei de Souza Santos Gabriela Graça Luciana lima Ricardo campos Barcellos Civil Police of Rio de Janeiro State Afranio Peixoto Medico-legal InstituteRio de JaneiroBrazil Anthropology department National MuseumFederal University of Rio de JaneiroRio de JaneiroBrazil

It is a well-established fact that forensic anthropology has been extremely helpful in identifying thermally altered human remains,especially in recent *** the improvement of new analytical techniques,the identification success rate has also been *** the help of statistical analysis,combined with analytical anthropological methods,the Forensic Anthropology Service of the Afranio Peixoto Medico-Legal Institute succeeded in identifying a charred body,with a margin of error of approximately 1:500 million to be obtained.

关键词： Forensic sciences forensic anthropology identification statistical analysis

Influence of physical-anatomical wood variables on charcoal physical-mechanical properties

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Journal of Forestry Research 2023年第2期34卷 531-538页

作者： Allan Motta Couto Thiago campos Monteiro Paulo Fernando Trugilho JoséTarcísio lima JoséReinaldo Moreira da Silva Alfredo Napoli Diego Pierre de Almeida department of Forestry Science State University of Mato Grosso do Sul–UEMSAv.Graziela Maciel BarrosoKm 12 Zona RuralAquidauanaMS 79200000Brazil department of Forestry Engineering and Technology Federal University of Paraná–UFPRA V.Pref.Lothário Meissner 632Jardim BotânicoCuritibaPR 80210170Brazil department of Forestry Science Federal UniversityLavras–UFLALavrasMG 37200000Brazil Département de Performance des Systèmes de Production Et de Transformation Tropicaux Centre de Coopération Internationale em Recherche Agronomique pour le Développement–CIRADMontpellierFrance

This research assessed the relationship between wood physical-anatomical variables and charcoal physical-mechanical *** trees were harvested and mechanically processed into standard pieces for laboratory *** following variables were determined:wood density,fiber length and width,fiber lumen diameter and wall thickness,fiber wall fraction,and vessel *** charcoal was produced in a laboratory and gravimetric yield,relative density,and mechanical properties ***’s correlation coefficients,multivariate statistical analysis of canonical correlation,and principal component analysis were used to evaluate the relationship between wood and charcoal *** width was not significantly correlated with charcoal *** bulk density,hardness,and strength were positively correlated with wood density,fiber length,wall thickness,and wall *** properties were negatively correlated with fiber lumen diameter and vessel *** results will help identify the best wood with adequate physical-mechanical properties for industrial charcoal proces sing.

关键词： Biomass density Energy Fiber Vessel

Intake,digestibility and nitrogen utilization in cattle fed tropical forage and supplemented with protein in the rumen,abomasum,or both

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Journal of Animal Science and Biotechnology 2016年第4期7卷 544-553页

作者： Luana Marta de Almeida Rufino Edenio detmann Daianyíris Gomes William lima Santiago dos Reis Erick Darlisson Batista Sebastiao de campos Valadares Filho Mário Fonseca Paulino department of Animal Science Universidade Federal de Viaosa department of Animal Science Universidade Federal Rural da Amaznia

Background： There is little information in the tropics with regard the comparative understanding of how an increased nitrogen supply in the rumen or in the intestines affects efficiency of nitrogen utilization in cattle. This study evaluated the effects of supplementation with nitrogenous compounds in the rumen, abomasum, or both on intake, digestibility and the characteristics of nitrogen utilization in cattle fed tropical forage. Four rumen- and abomasum-fistulated Nellore bulls （227 ± 11 kg） were used. Four treatments were evaluated： control, ruminal supplementation （230 g/d of supplemental protein in the rumen）, abomasal supplementation （230 g/d of supplemental protein in the abomasum）, and ruminal and abomasal supplementation （115 g/d protein in both the rumen and the abomasum）. The basal forage diet consisted of Tifton 85 hay with a crude protein （CP） level of 78.4 g/kg dry matter. Casein was used as a supplement. The experiment was conducted using a 4 x 4 Latin square. Results： There were no differences between the treatments （P 〉 0.10） with regard to forage intake. The intake and tota digestibility of CP increased （P 〈 0.01） with supplementation. The nitrogen balance in the body increased （P 〈 0.01） and muscle protein mobilization decreased （P 〈 0.01） with supplementation, regardless of the supplementation site. The efficiency of nitrogen utilization did not differ among the treatments （P 〉 0.10）. Conclusions： The supplementation of cattle fed tropical forage with protein in the rumen, abomasum, or both similarly increased the nitrogen accretion in animal, which reflects improvements on nitrogen status in animal body.

关键词： Casein Nitrogen balance Rumen ammonia nitrogen Supplementation 3-methylhistidine

Predictors of residual force enhancement in voluntary contractions of elbow flexors

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Journal of Sport and Health Science 2018年第3期7卷 318-325页

作者： Heiliane de Brito Fontana Daiani de campos Raphael Luiz Sakugawa Biological Sciences Center Federal University of Santa CatarinaCampus Reitor Joao David Ferreira LimaFlorianopoilsSC 88040-900Brazil Biomechanic Laboratory Federal University of Santa CatarinaCampus Reitor Joao David Ferreira LimaFlorianopolisSC 88040-900Brazil

Background:The steady-state increase in muscle force generating potential following a lengthening contraction is called residual force enhancement(RFE).In this study,we aimed to test for differences in torque,electromyographic activity(EMG),and the associated neuromuscular efficiency(NME)between isometric voluntary contractions of elbow flexors preceded and not preceded by a lengthening *** dependence of such differences on(i)stretch amplitude,(ii)the region of the force-length(FxL)relationship where contraction occurs,and(iii)the individual's ability to produce(negative)work during the stretch was ***:Sixteen healthy adults participated in the *** flexor torque,angle,and biceps brachii EMG for purely isometric contractions(reference contractions)and for isometric contractions preceded by active stretches of 20°and 40°were measured at the ascending,plateau,and descending regions of subject-specific FxL *** contractions were performed in an isokinetic ***-factor(stretch×FxL region)repeated measures analysis of variance ANOVAs was used to analyze the effect of active stretch on EMG,torque,and NME across *** relationships between mechanical work during stretch-calculated as the torque-angular displacement integral-and the changes in EMG,torque,and NME were analyzed using Pearson ***:In general,torque,EMG,and NME following active stretches differed from the values observed for the purely isometric reference *** although the detailed effects of active stretch on torque and EMG differed between regions of the FxL relationship,NME increased by about 19%for all muscle *** to 30%of the interindividual variability in torque generating potential change in response to active stretching was accounted for by differences in(negative)work capacity between ***:Our results suggest that(i)RFE contributes to"flatten"the elbow flexor torque-angle relationship,favoring

关键词： Force-length History-dependent properties Neuromuscular efficiency Upper limb Voluntary contractions

Immune thrombocytopenic purpura induced by intestinal tuberculosis in a liver transplant recipient

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World Journal of Gastroenterology 2014年第25期20卷 8304-8308页

作者： Renata dos Santos Lugao Marina Pamponet Motta Matheus Freitas Cardoso de Azevedo Roque Gabriel Rezende de lima Flávia de Azevedo Abrantes Edson Abdala Flair José Carrilho Daniel Ferraz de campos Mazo Hepatology Branch Clinical DivisionDepartment of GastroenterologyUniversity of S?o Paulo School of Medicine S?o Paulo 05403-000Brazil Liver and Gastrointestinal Transplant Division Department of GastroenterologyUniversity of S?o Paulo School of MedicineS?o Paulo 05403-000 Brazil department of Infectious and Parasitic Diseases University of S?o Paulo School of Medicine S?o Paulo 05403-000 Brazil

A variety of clinical manifestations are associated directly or indirectly with tuberculosis. Among them, haematological abnormalities can be found in both the pulmonary and extrapulmonary forms of the disease. We report a case of immune thrombocytopenic purpura(ITP) associated with intestinal tuberculosis in a liver transplant recipient. The initial management of thrombocytopenia, with steroids and intravenous immunoglobulin, was not successful, and the lack oftuberculosis symptoms hampered a proper diagnostic evaluation. After the diagnosis of intestinal tuberculosis and the initiation of specific treatment, a progressive increase in the platelet count was observed. The mechanism of ITP associated with tuberculosis has not yet been well elucidated, but this condition should be considered in cases of ITP that are unresponsive to steroids and intravenous immunoglobulin, especially in immunocompromised patients and those from endemic areas.

关键词： Immune thrombocytopenic purpura Tuberculosis Liver transplant Thrombocytopenia Intestinal tuberculosis

Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 330-335页

作者： Fabiola Rabelo Jose Tadeu Stefano Ana Mercedes Cavaleiro Rodrigo Vieira Costa lima Daniel Ferraz de campos Mazo Flair Jose Carrilho Maria Lúcia Correa-Giannellac Claudia P.Oliveiraa departamento de Gastroenterologia Faculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil Hospital das Clinicas HCFMUSP Departamento de GastroenterologiaLIM07Faculdade de MedicinaUniversidade de Sao PauloSao PauloSPBrazil Laboratório de Carboidratos e Radioimunensaio LIM18Hospital das Clinicas HCFMUSP(LIM07)Faculdade de MedicinaUniversidade de Sao PauloSao PauloBrazil Programa de Pos-Graduacao em Medicina Universidade Nove de Julho(UNINOVE)Sao PauloBrazil

Background: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease(NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for the first time two single nucleotide polymorphisms(SNPs) in the regulatory region of genes encoding NADPH oxidase 4(NOX4) and p22 phox(CYBA) in ***: A total of 207 biopsy-proven NAFLD patients [simple steatosis(n = 27); nonalcoholic steatohepatitis(NASH)(n = 180)] were evaluated. Genomic DNA was extracted from peripheral blood cells, and polymorphisms in CYBA(unregistered) and NOX4(rs3017887) were determined by direct sequencing of ***: Associations of CYBA-675 T/A with high-density lipoprotein(HDL)(TT vs TA vs AA; P des(TGL)(TT vs XA; P degrees of fibrosis occurred in patients diagnosed with type 2 diabetes mellitus(66.9% vs 37.5%, P degrees of fibrosis in NAFLD patients.

关键词： Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Genetic polymorphism Metabolic syndrome

Biomass-glycerol briquettes are not necessarily mechanically stable and energetically effective

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Waste Disposal and Sustainable Energy 2020年第4期2卷 291-303页

作者： Bruno Rafael de Almeida Moreira Ronaldo da Silva Viana Samuel Dias Moreira Monique dos Santos lima Anderson Chagas Magalhães Celso Tadao Miasaki Joséclaudio Caraschi department of Phytosanitary Rural Engineering and SoilsSchool of EngineeringSão Paulo State University(Unesp)Ilha SolteiraSão PauloBrazil department of Plant Production College of Agricultural and Technological SciencesSão Paulo State University(Unesp)DracenaBrazil São Paulo State University(Unesp) ItapevaSão PauloBrazil

The re-use of glycerol from biodiesel industry as an alternative lubricant for making high-performance briquettes is ***,the technical performance of this agro-industrial residue is not *** study outlines,accordingly,the real risk of introducing glycerol into the co-briquetting of highly caloric by-products of *** production of hybrid briquettes consisted of pressing mixtures of residues of sugarcane and sorghum with the liquid additive at 10,20,and 30 wt.%in bench-scale hydraulic piston presser *** of the blend,briquettes containing the supplement at the highest level as part of their composition ended up being much more hygroscopic(20.10%)and less energetic(3.15 GJ m^(−3)).The explanation for the negative impact of glycerol on the thermomechanical behavior of briquettes would be overconcen-tration of additive capable of effectively defying compacting *** degree of compaction during co-briquetting has likely gone down quickly with a maximizing level of *** long as the additive is not able to lubricate the feedstock suitably,improbability of biomass particles to successfully bond together to form themselves into mechanically stable and energetically effective briquettes is *** lower density(273.80 kg m^(−3))and higher relaxation(22.75%),briquettes with glycerol at 30 wt.%generally were aesthetically ***,these products resisted no longer to handling,transportation,and *** lost their shape easily during emptying and shifting them,thus,releasing larger quanti-ties of biomass to the *** evidence of high-viscosity glycerol capable of limiting safe and effective production of high-performance briquettes for heating and power exists.

关键词： Additive Agro-residues densification Biosolids Waste-to-energy

Experimental Acoustic determination of the Void Fraction in Two-Phase Flow in Horizontal Pipelines

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Journal of Mechanics Engineering and Automation 2014年第8期4卷 625-631页

作者： Fernando Augusto de Noronha Castro Pinto Thiago de campos Negrelly Alexandre Silva de lima Mechanical Engineering department UFRJ (Universidade Federal do Rio de Janeiro) Rio de Janeiro 21941-972 Brasil Mechanical Engineering department CEFET/RJ (Centro Federal de Educag6o Tecnologica Celso Suckow da Fonseca) Rio deJaneiro 20271-110 Brasil

In multi-phase flows, the phases can flow and arranged in different spatial configurations in the pipe, which called flow patterns. This type of flow is found in the oil, chemical and nuclear industries. For example, in the production and transport of oil and gas, the identification of the flow patterns are essential for answering those questions which are related to the economic return of the field, such as, measuring the volumetric flow, determining the pressure drop along the flow lines, production management and supervision. In offshore production, these factors are very important. This paper presents a new method for measuring the void fraction in horizontal pipelines, taking the air as gas in water-air two-phase flow. Through acoustic analysis of the frequency response of the pipe, the method gets the parameters to changes in runoff regime, in an experimental arrangement constructed on a small scale. The main advantages are the non-intrusive characteristic and easy to implement. The paper is composed of a qualitative experimental evaluation and transducers （microphone） which are used to analyze variations in the response accompanying variations in void and flow pattern changes. Changes are imposed and controlled by a two-phase flow experimental simulation rig, including a measurement cell constituted of an external casing that can isolate the measurement from the environmental background noise fitted with acoustic pressure transducers radially arranged, and the impact of a monitored excitation mechanism. The signals which captured by the microphones are processed and analyzed by checking their frequency contents changes according to the amount of air in the mixture.

关键词： Experimental method two-phase flow determination of void fraction horizontal pipelines.