检索结果-南通市图书馆

Zinc-mediated reactions on salicylaldehyde for Botrytis cinerea control

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2020年第3期31卷 706-710页

作者： Antoine Franche claire Imbs Antoine Fayeulle Franck Merlier Muriel Billamboz estelle Léonard Sorbonne University Universitéde technologie de CompiègneESCOMEA TIMR 4297Centre de recherche de RoyallieuCS 6031960203 Compiègne cedexFrance ESCOM UTCEA TIMR 42971 allée du Réseau Jean-Marie Buckmaster60200 CompiègneFrance Sorbonne Universités Universitéde Technologie de CompiègneGénie Enzymatique et Cellulaire(GEC)UMR-CNRS 7025CS 6031960203 Compiègne CedexFrance Laboratoire de chimie durable et santé Yncrea Hauts-de-FranceHEI13 rue de Toul59046 Lille CedexFrance

Botrytis cinerea is a necrotrophic fungusth at a ffects various plant *** control is an ecessity and as much as possible,eco-friendly conditions and bioresources to obtain these chemicals should be *** this context,a series of products w as obtained from salicylaldehyde using zinc as a powerful reagent and tested for antifungal activity against Botrytis cinerea.

关键词： Salicylaldehyde Zinc-mediated reactions Green solvents Alkoxymethylphenol PEG-cresol Botrytis cinerea control

Hepatocellular carcinoma with portal invasion,still a place for liver surgery in the era of immunotherapy?

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2022年第5期11卷 782-784页

作者： Héloïse Giudicelli claire Goumard Manon Allaire Service d’Hépato-Gastroentérologie Hôpital Universitaire Pitié-SalpêtrièreAP-HP Sorbonne UniversitéParisFrance Service de Chirurgie Hépatobiliopancréatique et Transplantation Hépatique Hôpital Universitaire Pitié-SalpêtrièreAP-HP Sorbonne UniversitéParisFrance

Hepatocellular carcinoma(HCC)is a leading cause of cancer death worldwide and is associated with a 5-year overall survival(OS)of 10-15%all stages ***,5-year OS reaches 50-70%when patients are in an early stage and can access curative treatments such as liver transplantation,liver resection(LR)or ***,LR is reserved to very selected patients with adequate performance status,preserved liver function,to be matched with grade of portal hypertension(PHT),sufficient volume of the future liver remnant and acceptable tumor burden(1,2).Worldwide,the definitions of“tumor burden”and vascular invasion vary as illustrated in Tables 1,2,and the impact of portal vein tumoral thrombosis(PVTT)on the choice for HCC treatment is not consensual(1,2).

关键词： treatment invasion matched

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

助人机器人如何影响人的亲社会性

商学院 2024年第1期 15-15页

作者： claire Zulkey 胡嘉琦(编译) 斯坦福商学院不详

斯坦福商学院市场营销学副教授黄祖智和澳门大学市场营销副教授陈方圆研究了助人机器人如何影响人类的亲社会性。黄祖智和陈方圆假设,派遣机器人救灾的坏处是亲社会行为的净损失。

关键词：机器人市场营销学澳门大学亲社会性亲社会行为黄祖斯坦福商学院助人

Endothelin increases the proliferation of rat olfactory mucosa cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2020年第2期15卷 352-360页

作者： Bertrand Bryche Audrey Saint-Albin claire Le Poupon Schlegel Christine Baly Patrice Congar Nicolas Meunier Neurobiologie de l'olfaction Institut National de Recherche Agronomique (INRA)Université Paris-SaclayJouy-en-JosasFrance Université de Versailles Saint-Quentin en Yvelines Département de BiologieVersaillesFrance

The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the whole animal life. Among several factors regulating this renewal, endothelin acts as an anti-apoptotic factor in the rat olfactory epithelium. In the present study, we explored whether endothelin could also act as a proliferative factor. Using primary culture of the olfactory mucosa, we found that an early treatment with endothelin increased its growth. Consistently, a treatment with a mixture of BQ123 and BQ788(endothelin receptor antagonists) decreased the primary culture growth without affecting the cellular death level. We then used combined approaches of calcium imaging, reverse transcriptase-quantitative polymerase chain reaction and protein level measurements to show that endothelin was locally synthetized by the primary culture until it reached confluency. Furthermore, in vivo intranasal instillation of endothelin receptor antagonists led to a decrease of olfactory mucosa cell expressing proliferating cell nuclear antigen(PCNA), a marker of proliferation. Only short-term treatment reduced the PCNA level in the olfactory mucosa cells. When the treatment was prolonged, the PCNA level was not statistically affected but the expression level of endothelin was increased. Overall, our results show that endothelin plays a proliferative role in the olfactory mucosa and that its level is dynamically regulated. This study was approved by the Comité d’éthique en expérimentation animale COMETHEA(COMETHEA C2 EA-45;protocol approval #12-058) on November 28, 2012.

关键词： autocrine factor cell culture cellular dynamics endothelin olfaction olfactory basal cells olfactory epithelium olfactory mucosa primary culture

Liver transplantation for hepatocellular carcinoma： is zero recurrence theoretically possible？

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic diseases International 2016年第2期15卷 147-151页

作者： Sabine Irtan Louise Barbier claire Francoz Federica dondéro Francois durand Jacques Belghiti department of Hepato-Pancreato-Biliary Surgery Beaujon HospitalAssistance Publique Hopitaux de ParisUniversity Denis Diderot-ParisⅦClichyFrance department of Hepatology Beaujon HospitalAssistance Publique Hopitaux de ParisUniversity Denis Diderot-ParisⅦClichyFrance

BACKGROUNd： Hepatocellular carcinoma（HCC） recurrence remains a key issue after liver transplantation. This study aimed to determine a subgroup of HCC patients within the Milan criteria who could achieve a theoretical goal of zero recurrence rates after liver ***： Between 1999 and 2009, 179 patients who received liver transplantation for HCC within the Milan criteria were retrospectively included. Analysis of the factors associated with HCC recurrence was performed to determine the subgroup of patients at the lowest risk of ***： Seventy-two percent of the patients received a bridging therapy, including 54 liver resections. Eleven（6.1%） patients recurred within a delay of 19±22 months and ultimately died. Factors associated with recurrence were serum alpha-fetoprotein level 〉400 ng/m L, satellite nodules, poor differentiation, microvascular invasion and cholangiocarcinoma component. Recurrence rates decreased from 6.1% to 3.1% in patients without any of these ***： Among HCC patients within the Milan criteria, selecting patients with factors based on histology would allow tending towards zero recurrence, and prior histological assessment by liver biopsy or resection may be essential to rule out poorly differentiated tumors, microvascular invasion,and cholangiocarcinoma component.

关键词： hepatocellular carcinoma liver transplantation neoplasm recurrence survival rate

The Extended Superomedial Pedicle: Advancing Mammaplasty Techniques

在线全文

学校读者我要写书评

暂无评论

Modern Plastic Surgery 2013年第1期3卷 20-27页

作者： Albert Losken Christopher d. Funderburk claire duggal division of Plastic and Reconstructive Surgery Emory Unversity Atlanta USA

Many variations can be applied to traditional mammoplasty techniques to improve outcomes in certain situations. The purpose of this report was to demonstrate the indications and benefits of mammoplasty autoaugmentation using an extended superomedial pedicle. All patients who underwent transfer of an extended superopedicleto other parts of the breast for autoaugmentation were included. Indications were determined and outcomes were assessed. Forty-eight patients were included in the series. The average follow-up was 2.1 years. Indications were categorized into reconstruction of a partial mastectomy defect (oncoplastic group, n = 18), upper pole volume in the contralateral mastopexy (implant reconstruction group, n = 9), and volume improvement and suspension (massive weight loss group, n = 21). The overall complication rate was 15% (n = 7/48), with a revision rate of 10% (5/48). The extended superomedial pedicle is a reliable and versatile adjunct to regular mastopexy techniques for various indications. It gives us the ability to transfer vascularized tissue from the lower pole to areas that require autoaugmentation.

关键词： Autoaugmentation Mastopexy Massive Weight Loss Oncoplastic

Effect of non-enzymatic glycation on collagen nanoscale mechanisms in diabetic and age-related bone fragility

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIOCELL 2023年第7期47卷 1651-1659页

作者： JAMES LROSENBERG WILLIAM WOOLLEY IHSAN ELNUNU JULIA KAMML dAVId SKAMMER claire ACEVEdO department of Mechanical Engineering University of UtahSalt Lake City84112USA Institute for Building Materials ETH ZurichZurichSwitzerland department of Biomedical Engineering University of UtahSalt Lake City84112USA

Age and diabetes have long been known to induce an oxidative reaction between glucose and collagen,leading to the accumulation of advanced glycation end-products(AGEs)cross-links in collagenous *** recently,AGEs content has been related to loss of bone quality,independent of bone mass,and increased fracture risk with aging and *** of bone quality is mostly attributed to changes in material properties,structural organization,or cellular *** all these factors play a role in bone fragility disease,some common recurring patterns can be found between diabetic and age-related bone *** main pattern we will discuss in this viewpoint is the increase of fibrillar collagen stiffness and loss of collagen-induced plasticity with AGE *** study focused on recent related experimental studies and discusses the correlation between fluorescent AGEs content at the molecular and fibrillar scales,collagen deformation mechanisms at the nanoscale,and resistance to bone fracture at the macroscale.

关键词： Bone fragility Advanced glycation end-products Collagen diabetes Aging

Managing dyslexia at university : a resource for students, academic and support staff /

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Managing dyslexia at university : a resource for students, a...

dairy sheep production research at the University of Wisconsin-Madison,USA-a review

2008年

作者： Jamieson claire.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Journal of Animal Science and Biotechnology 2014年第2期5卷 127-138页

作者： david L Thomas Yves M Berger Brett C McKusick claire M Mikolayunas University of Wisconsin-Madison Department of Animal Sciences Spooner Agricultural Research Station Current address:Merial Ltd Midwest Organic Services Association ViroquaWisconsinUSA

Commercial milking of sheep is a new agricultural industry in the United States starting approximately 30 yr ago. The industry is still small, but it is growing. The majority of the sheep milk is used in the production of specialty cheeses. The United States is the major importer of sheep milk cheeses with 50 to 60% of annual world exports coming to the United States during the past 20 yr. Therefore, there is considerable growth potential for the industry in the United States. The only dairy sheep research flock in North America is located at the Spooner Agricultural Research Station of the University of Wisconsin-Madison. The research program started in 1993 and has been multifaceted; dealing with several areas important to commercial dairy sheep farmers. The East Friesian and Lacaune dairy breeds were compared and introduced to the industry through the research program. Both dairy breeds produced significantly more milk than traditional meat-wool breeds found in the U.S., but the two breeds differed in their production traits. East Friesian-cross ewes produced more lambs and slightly more milk than Lacaune-cross ewes whereas Lacaune-cross ewes produced milk with a higher percentage of fat and protein than East Friesian-cross ewes. Lactation physiology studies have shown that ewes with active corpora lutea have increased milk yields, oxytocin release during milking is required to obtain normal fat percentages in the milk, large udder cisterns of dairy ewes can allow for increased milking intervals, and short daylengths during late pregnancy results in increased milk yield. In the nutrition area, legume-grass pastures and forages with a higher percentage of legume will result in increased milk production. Grazing ewes respond to additional supplementation with increased milk yield, but it is important to match the supplement to the quality of the grazing. Ewes on high quality legume-grass pastures that are high in rumen degradable protein respond with increased milk

关键词： dairy sheep East Friesian Grazing Lacaune Lactation physiology Nitrogen efficiency RdP RUP Supplementation